FK506 sensitizes mammalian cells to high osmolarity by modulating p38 MAP kinase activation

Cellular and Molecular Life Sciences

Volumn 61, Issue 6, 2004, Pages 700-708

  Sanchez Perez, I ^a,c   Rodriguez Hernandez, C J ^b   Manguan Garci C ^a   Torres, A ^b   Perona, R ^a   Murguia J R ^b  

^a INSTITUTO DE INVESTIGACIONES BIOMÉDICAS ALBERTO SOLS   (Spain)

^b HOSPITAL UNIVERSITARIO DE CANARIAS   (Spain)

^c NATIONAL INSTITUTE FOR MEDICAL RESEARCH   (United Kingdom)

Author keywords

Amino acid availability; Immunosuppressant; MAP kinase; Osmotic stress; Translational control

Indexed keywords

4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; CALCINEURIN; CISPLATIN; CYCLOSPORIN A; INITIATION FACTOR 2; INITIATION FACTOR 2ALPHA; MITOGEN ACTIVATED PROTEIN KINASE P38; PHOSPHOPROTEIN PHOSPHATASE; SORBITOL; TACROLIMUS; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; DIABETES MELLITUS; ENZYME ACTIVATION; HUMAN; HUMAN CELL; MAMMAL CELL; ORGAN TRANSPLANTATION; OSMOLARITY; OSMOTIC STRESS; PROTEIN PHOSPHORYLATION; T LYMPHOCYTE; T LYMPHOCYTE ACTIVATION;

CALCINEURIN; CELL DEATH; CELLS, CULTURED; CYCLOSPORINE; ENZYME ACTIVATION; EUKARYOTIC INITIATION FACTOR-2; HUMANS; IMMUNOSUPPRESSIVE AGENTS; KIDNEY; MITOGEN-ACTIVATED PROTEIN KINASES; OSMOLAR CONCENTRATION; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; SIGNAL TRANSDUCTION; SORBITOL; TACROLIMUS; TRYPTOPHAN;

EUKARYOTA; MAMMALIA;

EID: 1842558594     PISSN: 1420682X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00018-003-3388-x     Document Type: Article

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