Stabilization of the MDM2 Oncoprotein by Mutant p53

Journal of Biological Chemistry

Volumn 276, Issue 9, 2001, Pages 6874-6878

  Peng, Yanhua ^a   Chen, Lihong ^a   Li, Changgong ^a   Lu, Wenge ^a   Agrawal, Sudhir ^b   Chen, Jiandong ^a  

^a H LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE   (United States)

^b HYBRIDON INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DEGRADATION; PROTEINS; STABILIZATION; TUMORS; VIRUSES;

INDEPENDENT TRANSFORMING FUNCTIONS;

BIOCHEMISTRY;

COMPLEMENTARY DNA; MUTANT PROTEIN; ONCOPROTEIN; PROTEIN MDM2; PROTEIN P53; MDM2 PROTEIN, HUMAN; NUCLEAR PROTEIN;

ARTICLE; CANCER CELL CULTURE; CARCINOGENESIS; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; NONHUMAN; PRIORITY JOURNAL; TUMOR SUPPRESSOR GENE; VIRUS INFECTION; VIRUS RECOMBINANT; WESTERN BLOTTING; CELL CULTURE; CHEMISTRY; METABOLISM; MUTATION; NEOPLASM; PHYSIOLOGY;

ADENOVIRIDAE;

HUMANS; MUTATION; NEOPLASMS; NUCLEAR PROTEINS; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-MDM2; TUMOR CELLS, CULTURED; TUMOR SUPPRESSOR PROTEIN P53;

EID: 0035794143     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.C000781200     Document Type: Article

References (36)

1. Hollstein, M., Rice, K., Greenblatt, M. S., Soussi, T., Fuchs, R., Sorlie, T., Hovig, E., Smith-Sorensen, B., Montesano, R., and Harris, C. C. (1994) Nucleic Acids Res. 22, 3551-3555
2. Wu, X., Bayle, J. H., Olson, D., and Levine, A. J. (1993) Genes Dev. 7, 1126-1132
3. Barak, Y., Juven, T., Haffner, R., and Oren, M. (1993) EMBO J. 12, 461-468
4. Haupt, Y., Maya, R., Kazaz, A., and Oren, M. (1997) Nature 387, 296-299
5. Kubbutat, M. H. G., Jones, S. N., and Vousden, K. H. (1997) Nature 387, 299-303
6. Honda, R., Tanaka, H., and Yasuda, H. (1997) FEBS Lett. 420, 25-27
7. Oca Luna, R. M., Wagner, D. S., and Lozano, G. (1995) Nature 378, 203-206
8. Jones, S. N., Roe, A. E., Donehower, L. A., and Bradley, A. (1995) Nature 378, 206-208
9. Soong, R., Robbins, P. D., Dix, B. R., Grieu, F., Lim, B., Knowles, S., Williams, K. E., Turbett, G. R., House, A. K., and Iacopetta, B. J. (1996) Hum. Pathol. 27, 1050-1055
10. Cripps, K. J., Purdie, C. A., Carder, P. J., White, S., Komine, K., Bird, C. C., and Wyllie, A. H. (1994) Oncogene 9, 2739-2743
11. Dittmer, D., Pati, S., Zambetti, G., Chu, S., Teresky, A. K., Moore, M., Finlay, C., and Levine, A. J. (1993) Nat. Genet. 4, 42-46
12. Blandino, G., Levine, A. J., and Oren, M. (1999) Oncogene. 18, 477-485
13. Hsiao, M., Low, J., Dorn, E., Ku, D., Pattengale, P., Yeargin, J., and Haas, M. (1994) Am. J. Pathol. 145, 702-714
14. Frazier, M. W., He, X., Wang, J., Gu, Z., Cleveland, J. L., and Zambetti, G. P. (1998) Mol. Cell. Biol. 18, 3735-3743
15. Gualberto, A., Aldape, K., Kozakiewicz, K., and Tlsty, T. D. (1998) Proc. Natl. Acad. Sci. U. S. A. 95, 5166-5171
16. Lin, J., Teresky, A. K., and Levine, A. J. (1995) Oncogene. 10, 2387-2390
17. Juven-Gershon, T., and Oren, M. (1999) Mol. Med. 5, 71-83
18. Lundgren, K., Montes de Oca, Luna, R., McNeill, Y. B., Emerick, E. P., Spencer, B., Barfield, C. R., Lozano, G., Rosenberg, M. P., and Finlay, CA. (1997) Genes Dev. 11, 714-725
19. Jones, S. N., Hancock, A. R., Vogel, H., Donehower, L. A., and Bradley, A. (1998) Proc. Natl. Acad. Sci. U. S. A. 95, 15608-15612
20. Xiao, Z., Chen, J., Levine, A. J., Modjtahedi, N., Xing, J., Sellers, W. R., and Livingston, D. M. (1995) Nature 375, 694-698
21. Martin, K., Trouche, D., Hagemeier, C., Sorensen, T. S., La Thangue, N. B., and Kouzarides, T. (1995) Nature 375, 691-694
22. Loughran, O., and La, Thangue, N. B. (2000) Mol. Cell. Biol. 20, 2186-2197
23. Blattner, C., Sparks, A., and Lane, D. (1999) Mol. Cell. Biol. 19, 3704-3713
24. Sun, P., Dong, P., Dai, K., Hannon, G. J., and Beach, D. (1998) Science 282, 2270-2272
25. Landers, J. E., Haines, D. S., Strauss, J. F., and George, D. L. (1994) Oncogene 9, 2745-2750
26. Oliner, J. D., Kinzler, K. W., Meltzer, P. S., George, D. L., and Vogelstein, B. (1992) Nature 358, 80-83
27. Cordon Cardo, C., Latres, E., Drobnjak, M., Oliva, M. R., Pollack, D., Woodruff, J. M., Marechal, V., Chen, J., Brennan, M. F., and Levine, A. J. (1994) Cancer Res. 54, 794-799
28. Olson, D. C., Marechal, V., Momand, J., Chen, J., Romocki, C., and Levine, A. J. (1993) Oncogene 8, 2353-2360
29. Chen, J., Marechal, V., and Levine, A. J. (1993) Mol. Cell. Biol. 13, 4107-4114
30. Shaulian, E., Resnitzky, D., Shifman, O., Blandino, G., Amsterdam, A., Yayon, A., and Oren, M. (1997) Oncogene 15, 2717-2725
31. Ries, S., Biederer, C., Woods, D., Shifman, O., Shirasawa, S., Sasazuki, T., McMahon, M., Oren, M., and McCormick, F. (2000) Cell 103, 321-330
32. Pan, Y., and Haines, D. S. (1999) Cancer Res. 59, 2064-2067
33. Ende, K., Ueda, T., Ohta, T., and Terada, T. (2000) Liver 20, 209-215
34. Fang, S., Jensen, J. P., Ludwig, R. L., Vousden, K. H., and Weissman, A. M. (2000) J. Biol. Chem. 275, 8945-8951
35. Nagata, Y., Anan, T., Yoshida, T., Mizukami, T., Taya, Y., Fujiwara, T., Kato, H., Saya, H., and Nakao, M. (1999) Oncogene 18, 6037-6049
36. Midgley, C. A., and Lane, D. P. (1997) Oncogene 15, 1179-1189