In Vivo RNA Interference Analysis Reveals an Unexpected Role for GNBP1 in the Defense against Gram-positive Bacterial Infection in Drosophila Adults

Journal of Biological Chemistry

Volumn 279, Issue 13, 2004, Pages 12848-12853

  Pili Floury, Sebastien ^a,d   Leulier, François ^a   Takahashi, Kuniaki ^b   Saigo, Kaoru ^c   Samain, Emmanuel ^d   Ueda, Ryu ^b   Lemaitre, Bruno ^a  

^a CNRS   (France)

^b NATIONAL INSTITUTE OF GENETICS   (Japan)

^c UNIVERSITY OF TOKYO   (Japan)

^d UNIVERSITY HOSPITAL OF BESANÇON   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATION ANALYSIS; BACTERIA; BIOCHEMISTRY; GENES; IMMUNOLOGY; PATHOLOGY; RNA;

DROSOPHILA; IMMUNE DEFICIENCY (IMD);

PROTEINS;

DROSOMYCIN; GRAM NEGATIVE BINDING PROTEIN; PEPTIDOGLYCAN; PEPTIDOGLYCAN RECOGNITION PROTEIN; PROTEIN; PROTEIN GNBP1; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BACTERIAL INFECTION; BACTERIAL MEMBRANE; CELL KILLING; CONTROLLED STUDY; DROSOPHILA; GENE INDUCTION; GENE SILENCING; GENETIC ANALYSIS; GENETIC MODEL; GRAM POSITIVE BACTERIUM; HOST RESISTANCE; IMMUNE RESPONSE; IMMUNE SYSTEM; MOLECULAR RECOGNITION; NONHUMAN; PATTERN RECOGNITION; PRIORITY JOURNAL; RNA ANALYSIS; RNA INTERFERENCE; TRANSCRIPTION REGULATION;

ANIMALS; CARRIER PROTEINS; DROSOPHILA; DROSOPHILA PROTEINS; GENE SILENCING; GENETIC PREDISPOSITION TO DISEASE; GRAM-POSITIVE BACTERIAL INFECTIONS; PEPTIDES; PHENOTYPE; RECEPTORS, CELL SURFACE; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA INTERFERENCE; RNA, DOUBLE-STRANDED; SIGNAL TRANSDUCTION; TIME FACTORS; TOLL-LIKE RECEPTORS;

ANIMALIA; BACTERIA (MICROORGANISMS); BOMBYX; BOMBYX MORI; FUNGI; NEGIBACTERIA; POSIBACTERIA;

EID: 1842529395     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M313324200     Document Type: Article

References (38)

1. Girardin, S. E., Philpott, D. J., and Lemaitre, B. (2003) EMBO Rep. 4, 932-936
2. Tzou, P., De Gregorio, E., and Lemaitre, B. (2002) Curr. Opin. Microbiol. 5, 102-110
3. Hoffmann, J. A., and Reichhart, J. M. (2002) Nat. Immunol. 3, 121-126
4. Hultmark, D. (2003) Curr. Opin. Immunol. 15, 12-19
5. De Gregorio, E., Spellman, P. T., Tzou, P., Rubin, G. M., and Lemaitre, B. (2002) EMBO J. 21, 2568-2579
6. Boutros, M., Agaisse, H., and Perrimon, N. (2002) Dev. Cell 3, 711-722
7. Lemaitre, B., Reichhart, J., and Hoffmann, J. (1997) Proc. Natl. Acad. Sci. U. S. A. 94, 14614-14619
8. Leulier, F., Rodriguez, A., Khush, R. S., Abrams, J. M., and Lemaitre, B. (2000) EMBO Rep. 1, 353-358
9. Rutschmann, S., Jung, A. C., Hetru, C., Reichhart, J. M., Hoffmann, J. A., and Ferrandon, D. (2000) Immunity 12, 569-580
10. Rutschmann, S., Kilinc, A., and Ferrandon, D. (2002) J. Immunol. 168, 1542-1546
11. Hedengren, M., Asling, B., Dushay, M. S., Ando, I., Ekengren, S., Wihlborg, M., and Hultmark, D. (1999) Mol. Cell 4, 827-837
12. Vidal, S., Khush, R. S., Leulier, F., Tzou, P., Nakamura, M., and Lemaitre, B. (2001) Genes Dev. 15, 1900-1912
13. Kurata, S. (2004) Dev. Comp. Immunol. 28, 89-95
14. Yoshida, H., Kinoshita, K., and Ashida, M. (1996) J. Biol. Chem. 271, 13854-13860
15. Kang, D., Liu, G., Lundstrom, A., Gelius, E., and Steiner, H. (1998) Proc. Natl. Acad. Sci. U. S. A. 95, 10078-10082
16. Werner, T., Liu, G., Kang, D., Ekengren, S., Steiner, H., and Hultmark, D. (2000) Proc. Natl. Acad. Sci. U. S. A. 97, 13772-13777
17. Michel, T., Reichhart, J. M., Hoffmann, J. A., and Royet, J. (2001) Nature 414, 756-759
18. Choe, K. M., Werner, T., Stoven, S., Hultmark, D., and Anderson, K. V. (2002) Science 296, 359-362
19. Gottar, M., Gobert, V., Michel, T., Belvin, M., Duyk, G., Hoffmann, J. A., Ferrandon, D., and Royet, J. (2002) Nature 416, 640-644
20. Ramet, M., Manfruelli, P., Pearson, A., Mathey-Prevot, B., and Ezekowitz, R. A. (2002) Nature 416, 644-648
21. Takehana, A., Katsuyama, T., Yano, T., Oshima, Y., Takada, H., Aigaki, T., and Kurata, S. (2002) Proc. Natl. Acad. Sci. U. S. A. 99, 13705-13710
22. Leulier, F., Parquet, C., Pili-Floury, S., Ryu, J. H., Caroff, M., Lee, W. J., Mengin-Lecreulx, D., and Lemaitre, B. (2003) Nat. Immunol. 4, 478-484
23. Lee, W., Lee, J., Kravchenko, V., Ulevitch, R., and Brey, P. (1996) Proc. Natl. Acad. Sci. U. S. A. 93, 7888-7893
24. Beschin, A., Bilej, M., Hanssens, F., Raymakers, J., Van Dyck, E., Revets, H., Brys, L., Gomez, J., De Baetselier, P., and Timmermans, M. (1998) J. Biol. Chem. 273, 24948-24954
25. Lee, S. Y., Wang, R., and Soderhall, K. (2000) J. Biol. Chem. 275, 1337-1343
26. Ochiai, M., and Ashida, M. (2000) J. Biol. Chem. 275, 4995-5002
27. Ma, C., and Kanost, M. R. (2000) J. Biol. Chem. 275, 7505-7514
28. Kim, Y. S., Ryu, J. H., Han, S. J., Choi, K. H., Nam, K. B., Jang, I. H., Lemaitre, B., Brey, P. T., and Lee, W. J. (2000) J. Biol. Chem. 275, 32721-32727
29. Kalidas, S., and Smith, D. P. (2002) Neuron 33, 177-184
30. Leulier, F., Vidal, S., Saigo, K., Ueda, R., and Lemaitre, B. (2002) Curr. Biol. 12, 996-1000
31. Manfruelli, P., Reichhart, J. M., Steward, R., Hoffmann, J. A., and Lemaitre, B. (1999) EMBO J. 18, 3380-3391
32. Rutschmann, S., Jung, A. C., Zhou, R., Silverman, N., Hoffmann, J. A., and Ferrandon, D. (2000) Nat. Immunol. 1, 342-347
33. Tzou, P., Meister, M., and Lemaitre, B. (2002) Methods Microbiol. 31, 507-529
34. Reichhart, J. M., Ligoxygakis, P., Naitza, S., Woerfel, G., Imler, J. L., and Gubb, D. (2002) Genesis 34, 160-164
35. Ligoxygakis, P., Pelte, N., Hoffmann, J. A., and Reichhart, J. M. (2002) Science 297, 114-116
36. Lee, M. H., Osaki, T., Lee, J. Y., Baek, M. J., Zhang, R., Park, J. W., Kawabata, S. I., Soderhall, K., and Lee, B. L. (2003) J. Biol. Chem.
37. Akashi, S., Saitoh, S., Wakabayashi, Y., Kikuchi, T., Takamura, N., Nagai, Y., Kusumoto, Y., Fukase, K, Kusumoto, S., Adachi, Y., Kosugi, A., and Miyake, K. (2003) J. Exp. Med. 198, 1035-1042
38. Kim, M. S., Byun, M., and Oh, B. H. (2003) Nat. Immunol. 4, 787-793