Overexpression of β 1-adrenoceptors in adult rat ventricular myocytes enhances CGP 12177A cardiostimulation: Implications for 'putative' β 4-adrenoceptor pharmacology

British Journal of Pharmacology

Volumn 141, Issue 5, 2004, Pages 813-824

  Lewis, Clive J ^a   Gong, Haibin ^b   Brown, Morris J ^a   Harding, Sian E ^b  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b NATIONAL HEART AND LUNG INSTITUTE   (United Kingdom)

Author keywords

1 adrenoceptors; 'Putative' 4 adrenoceptor; Cardiomyocytes; CGP 12177A; Nonconventional partial agonists

Indexed keywords

4 (3 TERT BUTYLAMINO 2 HYDROXYPROPOXY) 2 BENZIMIDAZOLONE; ADENOSINE 3',5' PHOSPHOROTHIOATE; ADENOVIRUS VECTOR; BETA 1 ADRENERGIC RECEPTOR; BETA 4 ADRENERGIC RECEPTOR; BETA ADRENERGIC RECEPTOR; BUPRANOLOL; CYANOPINDOLOL; CYCLIC AMP; GREEN FLUORESCENT PROTEIN; INOTROPIC AGENT; IODINE 125; ISOBUTYLMETHYLXANTHINE; ISOPRENALINE; PHOSPHODIESTERASE INHIBITOR; PROPRANOLOL; TRITIUM; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; CELL ISOLATION; DRUG EFFECT; DRUG MECHANISM; DRUG RECEPTOR BINDING; GENE OVEREXPRESSION; HEART ARRHYTHMIA; HEART MUSCLE CELL; HEART STIMULATION; HEART VENTRICLE; INOTROPISM; ISOLATED HEART; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; RAT STRAIN; SIGNAL TRANSDUCTION;

ANIMALS; CARDIOTONIC AGENTS; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; GENE EXPRESSION REGULATION; HEART VENTRICLES; HUMANS; MALE; MYOCYTES, CARDIAC; PROPANOLAMINES; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, ADRENERGIC, BETA; RECEPTORS, ADRENERGIC, BETA-1;

EID: 1842507477     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0705668     Document Type: Article

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