Signal processing in migrating T24 human bladder carcinoma cells: Role of the autocrine interleukin-8 loop

International Journal of Cancer

Volumn 99, Issue 5, 2002, Pages 673-680

  Lang, Kerstin ^a   Niggemann, Bernd ^a   Zanker, Kurt S ^a   Entschladen, Frank ^a  

^a UNIVERSITY OF WITTEN HERDECKE   (Germany)

Author keywords

Bladder carcinoma; Calcium; Cell migration; Interleukin 8; Signal transduction

Indexed keywords

BETA ARRESTIN; DIACYLGLYCEROL; INOSITOL 1,4,5 TRISPHOSPHATE; INTERLEUKIN 8; INTERLEUKIN 8 RECEPTOR; PHOSPHOLIPASE C; PROTEIN KINASE C; PROTEIN TYROSINE KINASE; SERPENTINE;

ARTICLE; AUTOCRINE EFFECT; BLADDER CARCINOMA; CALCIUM TRANSPORT; CANCER CELL CULTURE; CELL MIGRATION; CELL MOTION; CONTROLLED STUDY; ENDOPLASMIC RETICULUM; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; SECOND MESSENGER; SIGNAL PROCESSING; SIGNAL TRANSDUCTION;

ANTIBODIES; ARRESTINS; CALCIUM; CELL MOVEMENT; DIGLYCERIDES; ENZYME ACTIVATION; HUMANS; INOSITOL 1,4,5-TRISPHOSPHATE; INTERLEUKIN-8; IONOMYCIN; ISOENZYMES; KINETICS; MICROSCOPY, CONFOCAL; PHOSPHOLIPASE C; PHOSPHOLIPASE C GAMMA; PROTEIN KINASE C; PROTEIN-TYROSINE KINASES; RECEPTORS, INTERLEUKIN-8A; SECOND MESSENGER SYSTEMS; SIGNAL TRANSDUCTION; TETRADECANOYLPHORBOL ACETATE; TUMOR CELLS, CULTURED; URINARY BLADDER NEOPLASMS;

EID: 0036102570     PISSN: 00207136     EISSN: None     Source Type: Journal    
DOI: 10.1002/ijc.10424     Document Type: Article

References (36)

1. Chemokines - Chemotactic cytokines that mediate inflammation
2. T lymphocytes and neutrophil granulocytes differ in regulatory signaling and migratory dynamics with regard to spontaneous locomotion and chemotaxis
3. Inflammation and cancer: Back to Virchow?
4. The origin and function of tumor-associated macrophages
5. The detection and localization of monocyte chemoattractant protein-1 (MCP-1) in human ovarian cancer
6. Elevated expression of the CC chemokine regulated on activation, normal T cell expressed and secreted (RANTES) in advanced breast carcinoma
7. Chemokine receptor expression by human intestinal epithelial cells
8. Cytokine repertoire of epithelial cells lining the urinary tract
9. The tumorigenic and angiogenic effects of MGSA/GRO proteins in melanoma
10. IL-8 produced by human malignant melanoma cells in vitro is an essential autocrine growth factor
11. Expression of interleukin-8 correlates with the metastatic potential of human melanoma cells in nude mice
12. Norepinephrine-induced migration of SW 480 colon carcinoma cells is inhibited by β-blockers
13. High PKCα and low E-cadherin expression contribute to high migratory activity of colon carcinoma cells
14. Lessons from tumor and immunocompetent cells. The quantitative engagement of ligand-receptor interactions modulates stop-and-go behavior as well as proliferation
15. Locomotory phenotypes of human tumor cell lines and T lymphocytes in a three-dimensional collagen lattice
16. Phospholipases C and D in mitogenic signal transduction
17. Src tyrosine kinase is a novel direct effector of G proteins
18. Transepithelial neutrophil migration is CXCR1 dependent in vitro and is defective in IL-8 receptor knockout mice
19. Beta-arrestin-dependent formation of β2 adrenergic receptor-src protein kinase complexes
20. Regulation of tyrosine kinase activation and granule release through beta-arrestin by CXCR1
21. Beta-arrestin1 interacts with the catalytic domain of the tyrosine kinase c-SRC. Role of beta-arrestin1-dependent targeting of c-SRC in receptor endocytosis
22. Calcium signaling
23. Protein kinase C isozymes and substrates
24. Phosphorylation of cardiac junctional and free sarcoplasmatic reticulum by PKC alpha, PKC beta, PKA and the Ca2+/calmodulin-dependent protein kinase
25. The role of phospholamban and SERCA3 in regulation of smooth muscle-endothelial cell signalling mechanisms: Evidence from gene-ablated mice
26. Thapsigargin, a tumor promoter, discharges intracellular Ca2+ stores by specific inhibition of the endoplasmic reticulum Ca2(+)-ATPase
27. Elementary and global aspects of calcium signalling
28. The MARCKS brothers: A family of protein kinase C substrates
29. Gelsolin binding to phosphatidylinositol 4,5-bisphosphate is modulated by calcium and pH
30. The molecular architecture of focal adhesions
31. Dependence of fibroblast migration on actin severing activity of gelsolin
32. Control of actin dynamics in cell motility. Role of ADF/cofilin
33. C-erbB-2/EGFR as dominant heterodimerization partners determine a motogenic phenotype in human breast cancer cells
34. Calcium is a key signaling molecule in the migration of tumor cells and leukocytes
35. The machinery of blood cell movement
36. Cell migration: A physically integrated molecular process