-
1
-
-
0034847378
-
The Physics of Molecular Motors
-
Bustamante, C., Keller, D., and Oster, G. (2001) The Physics of Molecular Motors, Acc. Chem. Res. 34, 412-420.
-
(2001)
Acc. Chem. Res.
, vol.34
, pp. 412-420
-
-
Bustamante, C.1
Keller, D.2
Oster, G.3
-
2
-
-
0037333239
-
Rotary Protein Motors
-
Oster, G., and Wang, H. Y. (2003) Rotary Protein Motors, Trends Cell Biol. 13, 114-121.
-
(2003)
Trends Cell Biol.
, vol.13
, pp. 114-121
-
-
Oster, G.1
Wang, H.Y.2
-
3
-
-
0034111877
-
The Mechanochemistry of Molecular Motors
-
Keller, D., and Bustamante, C. (2000) The Mechanochemistry of Molecular Motors, Biophys. J. 78, 541-556.
-
(2000)
Biophys. J.
, vol.78
, pp. 541-556
-
-
Keller, D.1
Bustamante, C.2
-
4
-
-
0032518398
-
Crystal structure of a bacteriophage T7 DNA replication complex at 2.2 Å resolution
-
Doublie, S., Tabor, S., Long, A. M., Richardson, C. C., and Ellenberger, T. (1998) Crystal structure of a bacteriophage T7 DNA replication complex at 2.2 Å resolution, Nature 391, 251-258.
-
(1998)
Nature
, vol.391
, pp. 251-258
-
-
Doublie, S.1
Tabor, S.2
Long, A.M.3
Richardson, C.C.4
Ellenberger, T.5
-
5
-
-
0033578332
-
Structure-based Design of Taq DNA Polymerase with Improved Properties of Dideoxynucleotide Incorporation
-
Li, Y., Mitaxov, V., and Waksman, G. (1999) Structure-based Design of Taq DNA Polymerase with Improved Properties of Dideoxynucleotide Incorporation, Proc. Natl. Acad. Sci. U.S.A. 96, 9491-9496.
-
(1999)
Proc. Natl. Acad. Sci. U.S.A.
, vol.96
, pp. 9491-9496
-
-
Li, Y.1
Mitaxov, V.2
Waksman, G.3
-
6
-
-
0028983795
-
Crystal structure of Thermits aquaticus DNA polymerase
-
Kim, Y., Eom, S. H., Wang, J., Lee, D. S., Suh, S. W., and Steitz, T. A. (1995) Crystal structure of Thermits aquaticus DNA polymerase, Nature 376, 612-616.
-
(1995)
Nature
, vol.376
, pp. 612-616
-
-
Kim, Y.1
Eom, S.H.2
Wang, J.3
Lee, D.S.4
Suh, S.W.5
Steitz, T.A.6
-
7
-
-
0032518524
-
Visualizing DNA replication in a catalytically active Bacillus DNA polymerase crystal
-
Kiefer, J. R., Mao, C., Braman, J. C., and Beese, L. S. (1998) Visualizing DNA replication in a catalytically active Bacillus DNA polymerase crystal, Nature 391, 304-307.
-
(1998)
Nature
, vol.391
, pp. 304-307
-
-
Kiefer, J.R.1
Mao, C.2
Braman, J.C.3
Beese, L.S.4
-
8
-
-
0032573488
-
Structure of a covalently trapped catalytic complex of HIV-1 reverse transcriptase: Implications for drug resistance
-
Huang, H., Chopra, R., Vereine, G. L., and Harrison, S. C. (1998) Structure of a covalently trapped catalytic complex of HIV-1 reverse transcriptase: Implications for drug resistance, Science 282, 1669-1675.
-
(1998)
Science
, vol.282
, pp. 1669-1675
-
-
Huang, H.1
Chopra, R.2
Vereine, G.L.3
Harrison, S.C.4
-
9
-
-
0033621167
-
Lamivudine (3TC) Resistance in HIV-1 reverse transcriptase involves steric hindrance with β-branched amino acids
-
Sarafianos, S. G., Das, K., Clark, A. D., Jr., Ding, J., Boyer, P. L., Hughes, S. H., and Arnold, E. (1999) Lamivudine (3TC) Resistance in HIV-1 reverse transcriptase involves steric hindrance with β-branched amino acids, Proc. Natl. Acad. Sci. U.S.A. 96, 10027-10032.
-
(1999)
Proc. Natl. Acad. Sci. U.S.A.
, vol.96
, pp. 10027-10032
-
-
Sarafianos, S.G.1
Das, K.2
Clark Jr., A.D.3
Ding, J.4
Boyer, P.L.5
Hughes, S.H.6
Arnold, E.7
-
10
-
-
0035868713
-
Crystal structure of HIV-1 reverse transcriptase in complex with a polypurine tract, RNA:DNA
-
Sarafianos, S. G., Das, K., Tantillo, C., Clark, A. D., Jr., Ding, J., Whitcomb, J., Boyer, P. L., Hughes, S. H., and Arnold, E. (2001) Crystal structure of HIV-1 reverse transcriptase in complex with a polypurine tract, RNA:DNA, EMBO J. 20, 1449-1461.
-
(2001)
EMBO J.
, vol.20
, pp. 1449-1461
-
-
Sarafianos, S.G.1
Das, K.2
Tantillo, C.3
Clark Jr., A.D.4
Ding, J.5
Whitcomb, J.6
Boyer, P.L.7
Hughes, S.H.8
Arnold, E.9
-
11
-
-
0032509101
-
Structure and functional implications of the polymerase active site region in a complex of HIV-1 RT with a double stranded DNA template primer and an antibody fAb fragment at 2.8 Å resolution
-
Ding, J., Das, K., Hsiou, Y., Sarafianos, S. G., Clark, A. D., Jr., Jacobo-Molina, A., Tantillo, C., Hughes, S. H., and Arnold, E. (1998) Structure and functional implications of the polymerase active site region in a complex of HIV-1 RT with a double stranded DNA template primer and an antibody fAb fragment at 2.8 Å resolution, J. Mol. Biol. 284, 1095-1111.
-
(1998)
J. Mol. Biol.
, vol.284
, pp. 1095-1111
-
-
Ding, J.1
Das, K.2
Hsiou, Y.3
Sarafianos, S.G.4
Clark Jr., A.D.5
Jacobo-Molina, A.6
Tantillo, C.7
Hughes, S.H.8
Arnold, E.9
-
12
-
-
0035369086
-
Structure of the replicating complex of a pol α family DNA polymerase
-
Franklin, M. C., Wang, J., and Steitz, T. A. (2001) Structure of the replicating complex of a pol α family DNA polymerase, Cell 105, 657-667.
-
(2001)
Cell
, vol.105
, pp. 657-667
-
-
Franklin, M.C.1
Wang, J.2
Steitz, T.A.3
-
13
-
-
0030930760
-
Crystal structures of human DNA polymerase β complexed with gapped and nicked DNA: Evidence for an induced fit mechanism
-
Sawaya, M. R., Prasad, R., Wilson, S. H., Kraut, J., and Pelletier, H. (1997) Crystal structures of human DNA polymerase β complexed with gapped and nicked DNA: Evidence for an induced fit mechanism, Biochemistry 36, 11205-11215.
-
(1997)
Biochemistry
, vol.36
, pp. 11205-11215
-
-
Sawaya, M.R.1
Prasad, R.2
Wilson, S.H.3
Kraut, J.4
Pelletier, H.5
-
14
-
-
0035826622
-
Insight into the catalytic mechanism of DNA polymerase β: Structures of intermediate complexes
-
Arndt, J. W., Gong, W., Zhong, X., Showalter, A. K., Liu, J., Dunlap, C. A., Lin, Z., Paxson, C., Tsai, M.-D., and Chan, M. K. (2001) Insight into the catalytic mechanism of DNA polymerase β: Structures of intermediate complexes, Biochemistry 40, 5368-5375.
-
(2001)
Biochemistry
, vol.40
, pp. 5368-5375
-
-
Arndt, J.W.1
Gong, W.2
Zhong, X.3
Showalter, A.K.4
Liu, J.5
Dunlap, C.A.6
Lin, Z.7
Paxson, C.8
Tsai, M.-D.9
Chan, M.K.10
-
15
-
-
0027220197
-
Conformational Coupling in DNA Polymerase Fidelity
-
Johnson, K. A. (1993) Conformational Coupling in DNA Polymerase Fidelity, Annu. Rev. Biochem. 62, 685-713.
-
(1993)
Annu. Rev. Biochem.
, vol.62
, pp. 685-713
-
-
Johnson, K.A.1
-
16
-
-
0027365750
-
Kinetic Mechanism of the DNA-dependent DNA Polymerase Activity of Human Immunodeficiency Virus Reverse Transcriptase
-
Hseih, J.-C., Zinnen, S., and Modrich, P. (1993) Kinetic Mechanism of the DNA-dependent DNA Polymerase Activity of Human Immunodeficiency Virus Reverse Transcriptase, J. Biol. Chem. 268, 24607-24613.
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 24607-24613
-
-
Hseih, J.-C.1
Zinnen, S.2
Modrich, P.3
-
17
-
-
0030918969
-
Analysis of Nucleotide Insertion and Extension at 8-Oxo-7,8- dihydroguanine by Replicative T7 Polymerase exo- and Human Immunodeficiency Virus-1 Reverse Transcriptase Using Steady-State and Pre-Steady-State Kinetics
-
Furge, L. L., and Guengerich, F. P. (1997) Analysis of Nucleotide Insertion and Extension at 8-Oxo-7,8-dihydroguanine by Replicative T7 Polymerase exo- and Human Immunodeficiency Virus-1 Reverse Transcriptase Using Steady-State and Pre-Steady-State Kinetics, Biochemistry 36, 6475-6487.
-
(1997)
Biochemistry
, vol.36
, pp. 6475-6487
-
-
Furge, L.L.1
Guengerich, F.P.2
-
18
-
-
0037154082
-
Effect of the O6 Substituent on Misincorporation Kinetics Catalyzed by DNA Polymerases at O6-Methylguanine and O6-Benzylguanine
-
Woodside, A. M., and Guengerich, F. P. (2002) Effect of the O6 Substituent on Misincorporation Kinetics Catalyzed by DNA Polymerases at O6-Methylguanine and O6-Benzylguanine, Biochemistry 41, 1027-1038.
-
(2002)
Biochemistry
, vol.41
, pp. 1027-1038
-
-
Woodside, A.M.1
Guengerich, F.P.2
-
19
-
-
0037154103
-
Misincorporation and Stalling at O6-Methylguanine and O6-Benzylguanine: Evidence for Inactive Polymerase Complexes
-
Woodside, A. M., and Guengerich, F. P. (2002) Misincorporation and Stalling at O6-Methylguanine and O6-Benzylguanine: Evidence for Inactive Polymerase Complexes, Biochemistry 41, 1039-1050.
-
(2002)
Biochemistry
, vol.41
, pp. 1039-1050
-
-
Woodside, A.M.1
Guengerich, F.P.2
-
20
-
-
0029883809
-
Kinetic Analysis of Pausing and Fidelity of Human Immunodeficiency Virus Type 1 Reverse Transcription
-
Pop, M. P., and Biebricher, C. K. (1996) Kinetic Analysis of Pausing and Fidelity of Human Immunodeficiency Virus Type 1 Reverse Transcription, Biochemistry 35, 5054-5062.
-
(1996)
Biochemistry
, vol.35
, pp. 5054-5062
-
-
Pop, M.P.1
Biebricher, C.K.2
-
21
-
-
0027092323
-
Mechanism and Fidelity of HIV Reverse Transcriptase
-
Kati, W. M., Johnson, K. A., Jerva, L. F., and Anderson, K. S. (1992) Mechanism and Fidelity of HIV Reverse Transcriptase, J. Biol. Chem. 267, 25988-25997.
-
(1992)
J. Biol. Chem.
, vol.267
, pp. 25988-25997
-
-
Kati, W.M.1
Johnson, K.A.2
Jerva, L.F.3
Anderson, K.S.4
-
22
-
-
0034594940
-
Single-Molecule Studies of the Effect of Template Tension on T7 DNA Polymerase Activity
-
Wuite, G. J. L., Smith, S. B., Young, M., Keller, D., and Bustamante, C. (2000) Single-Molecule Studies of the Effect of Template Tension on T7 DNA Polymerase Activity, Nature 404, 103-106.
-
(2000)
Nature
, vol.404
, pp. 103-106
-
-
Wuite, G.J.L.1
Smith, S.B.2
Young, M.3
Keller, D.4
Bustamante, C.5
-
23
-
-
0343811737
-
Single-Step Kinetics of HIV-1 Reverse Transcriptase Mutants Responsible for Virus Resistance to Nucleoside Inhibitors Zidovudine and 3-TC
-
Krebs, R., Immendorfer, U., Thrall, S. H., Wohrl, B. M., and Goody, R. S. (1997) Single-Step Kinetics of HIV-1 Reverse Transcriptase Mutants Responsible for Virus Resistance to Nucleoside Inhibitors Zidovudine and 3-TC, Biochemistry 36, 10292-10300.
-
(1997)
Biochemistry
, vol.36
, pp. 10292-10300
-
-
Krebs, R.1
Immendorfer, U.2
Thrall, S.H.3
Wohrl, B.M.4
Goody, R.S.5
-
24
-
-
0030703245
-
Pre-Steady-State Kinetic Characterization of Wild-Type and 3′-Azido-3′-deoxythymidine (AZT) Resistant Human Immunodeficiency Virus Type 1 Reverse Transcriptase: Implication of RNA Directed DNA Polymerization in the Mechanism of AZT Resistance
-
Kerr, S. G., and Anderson, K. S. (1997) Pre-Steady-State Kinetic Characterization of Wild-Type and 3′-Azido-3′-deoxythymidine (AZT) Resistant Human Immunodeficiency Virus Type 1 Reverse Transcriptase: Implication of RNA Directed DNA Polymerization in the Mechanism of AZT Resistance, Biochemistry 36, 14064-14070.
-
(1997)
Biochemistry
, vol.36
, pp. 14064-14070
-
-
Kerr, S.G.1
Anderson, K.S.2
-
25
-
-
0038143190
-
Dioxolane Guanosine 5′-Triphosphate, an Alternative Substrate Inhibitor of Wild-type and Mutant HTV-1 Reverse Transcriptase
-
Jeffrey, J. L., Feng, J. Y., Qi, C. C. R., Anderson, K. S., and Furman, P. A. (2003) Dioxolane Guanosine 5′-Triphosphate, an Alternative Substrate Inhibitor of Wild-type and Mutant HTV-1 Reverse Transcriptase, J. Biol. Chem. 278, 18971-18979.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 18971-18979
-
-
Jeffrey, J.L.1
Feng, J.Y.2
Qi, C.C.R.3
Anderson, K.S.4
Furman, P.A.5
-
26
-
-
0030859022
-
Kinetic Analysis of Four HIV-1 Reverse Transcriptase Enzymes Mutated in the Primer Grip Region of p66
-
Wohrl, B. M., Krebs, R., Thralli, S. H., Le Grice, S. F. J., Scheidig, A. J., and Goody, R. S. (1997) Kinetic Analysis of Four HIV-1 Reverse Transcriptase Enzymes Mutated in the Primer Grip Region of p66, J. Biol. Chem. 272, 17581-17587.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 17581-17587
-
-
Wohrl, B.M.1
Krebs, R.2
Thralli, S.H.3
Le Grice, S.F.J.4
Scheidig, A.J.5
Goody, R.S.6
-
27
-
-
0028033532
-
Misincorporation and Mispaired Primer Extension by Human Immunodeficiency Virus Reverse Transcriptase
-
Zinnen, S., Hsieh, J.-C., and Modrich, P. (1994) Misincorporation and Mispaired Primer Extension by Human Immunodeficiency Virus Reverse Transcriptase, J. Biol. Chem. 269, 24195-24202.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 24195-24202
-
-
Zinnen, S.1
Hsieh, J.-C.2
Modrich, P.3
-
28
-
-
0029670612
-
HIV-1 Reverse Transcriptase Resistance to Nonnucleoside Inhibitors
-
Spence, R. A., Anderson, K. S., and Johnson, K. A. (1996) HIV-1 Reverse Transcriptase Resistance to Nonnucleoside Inhibitors, Biochemistry 35, 1054-1063.
-
(1996)
Biochemistry
, vol.35
, pp. 1054-1063
-
-
Spence, R.A.1
Anderson, K.S.2
Johnson, K.A.3
-
29
-
-
0036829992
-
The Molecular Mechanism of Multidrug Resistance by the Q151M Human Immunodeficiency Virus Type 1 Reverse Transcriptase and Its Suppression Using Boranophosphate Nucleotide Analogues
-
Deval, J., Selmi, B., Boretto, J., Egloff, M. P., Guerreiro, C., Sarfati, S., and Canard, B. (2002) The Molecular Mechanism of Multidrug Resistance by the Q151M Human Immunodeficiency Virus Type 1 Reverse Transcriptase and Its Suppression Using Boranophosphate Nucleotide Analogues, J. Biol. Chem. 277, 42097-42104.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 42097-42104
-
-
Deval, J.1
Selmi, B.2
Boretto, J.3
Egloff, M.P.4
Guerreiro, C.5
Sarfati, S.6
Canard, B.7
-
30
-
-
11144227942
-
Closing of the Fingers Domain Generates Motor Forces in the HIV Reverse Transcriptase
-
Lu, H., Macosko, J., Habel-Rodriquez, D., Keller, R. W., Brozik, J. A., and Keller, D. J. (2004) Closing of the Fingers Domain Generates Motor Forces in the HIV Reverse Transcriptase, J. Biol. Chem. 279, 54529-54532.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 54529-54532
-
-
Lu, H.1
Macosko, J.2
Habel-Rodriquez, D.3
Keller, R.W.4
Brozik, J.A.5
Keller, D.J.6
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