Differential metabolism of benzo[a]pyrene and benzo[a]pyrene-7,8-dihydrodiol by human CYP1A1 variants

Carcinogenesis

Volumn 22, Issue 3, 2001, Pages 453-459

  Schwarz, Dieter ^a   Kisselev, Pyotr ^b   Cascorbi, Ingolf ^a   Schunck, Wolf Hagen ^c   Roots, Ivar ^a  

^a CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^b INSTITUTE OF BIOORGANIC CHEMISTRY   (Belarus)

^c MAX DELBRÜCK CENTER FOR MOLECULAR MEDICINE   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

7,8 DIHYDRO 7,8 DIHYDROXYBENZO[A]PYRENE; BENZO[A]PYRENE; CARCINOGEN; CYTOCHROME P450 1A1; CYTOCHROME P450 REDUCTASE; DIHYDROXYBENZO[A]PYRENE OXIDE; ENZYME VARIANT; EPOXIDE HYDROLASE; MEMBRANE ENZYME; RECOMBINANT ENZYME; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE;

ALLELE; ARTICLE; BACULOVIRUS; CANCER SUSCEPTIBILITY; CHEMICAL CARCINOGENESIS; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME KINETICS; ENZYME MECHANISM; ENZYME METABOLISM; ENZYME POLYMORPHISM; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HYDROLYSIS; INSECT; METABOLIC REGULATION; METABOLITE; MICROSOME MEMBRANE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; TOXICITY TESTING;

EID: 0035090669     PISSN: 01433334     EISSN: None     Source Type: Journal    
DOI: 10.1093/carcin/22.3.453     Document Type: Article

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