메뉴 건너뛰기




Volumn 93, Issue 3, 2005, Pages 715-723

Allosteric modulation of adenosine A1 receptor coupling to G-proteins in brain

Author keywords

35S GTP S; Adenosine A1 receptor; Allosteric; Autoradiography; G proteins; Modulator

Indexed keywords

2 AMINO 4,5,6 TETRAHYDROBENZO(BETA)THIOPHEN 3 YL 4 CHLOROPHENYLMETHANONE; ADENOSINE A1 RECEPTOR; G PROTEIN COUPLED RECEPTOR; GUANOSINE 5' O (3 THIOTRIPHOSPHATE); PHENYLISOPROPYLADENOSINE; UNCLASSIFIED DRUG;

EID: 18144408044     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2005.03044.x     Document Type: Article
Times cited : (40)

References (34)
  • 1
    • 0033922489 scopus 로고    scopus 로고
    • Differential a (1)-adenosine receptor reserve for inhibition of cyclic AMP accumulation and G-protein activation in DDT (1) MF-2 cells
    • Baker S. P., Scammells P. J. and Belardinelli L. (2000) Differential A (1)-adenosine receptor reserve for inhibition of cyclic AMP accumulation and G-protein activation in DDT (1) MF-2 cells. Br. J. Pharmacol. 130, 1156-1164.
    • (2000) Br. J. Pharmacol. , vol.130 , pp. 1156-1164
    • Baker, S.P.1    Scammells, P.J.2    Belardinelli, L.3
  • 4
    • 0017184389 scopus 로고
    • A rapid and sensitive method for the quantification of microgram quantities of protein utilizing the principle of protein-dye binding
    • Bradford M. M. (1976) A rapid and sensitive method for the quantification of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72, 248-254.
    • (1976) Anal. Biochem. , vol.72 , pp. 248-254
    • Bradford, M.M.1
  • 5
    • 0025603686 scopus 로고
    • 1 receptor binding and function by 2-amino-3-benzoylthiophenes
    • 1 receptor binding and function by 2-amino-3-benzoylthiophenes. Mol. Pharmacol. 38, 939-949.
    • (1990) Mol. Pharmacol. , vol.38 , pp. 939-949
    • Bruns, R.F.1    Fergus, J.H.2
  • 7
    • 0032959061 scopus 로고    scopus 로고
    • Intrathecal adenosine: Interactions with spinal clonidine and neostigmine in rat models of acute nociception and postoperative surgery
    • Chiari A. I. and Eisenach J. C. (1999) Intrathecal adenosine: Interactions with spinal clonidine and neostigmine in rat models of acute nociception and postoperative surgery. Anesthesiology 90, 1413-1421.
    • (1999) Anesthesiology , vol.90 , pp. 1413-1421
    • Chiari, A.I.1    Eisenach, J.C.2
  • 8
    • 2342446466 scopus 로고    scopus 로고
    • Pharmacological characterization of the chronic constriction injury model of neuropathic pain
    • De Vry J., Kuhl E., Franken-Kunkel P. and Eckel G. (2004) Pharmacological characterization of the chronic constriction injury model of neuropathic pain. Eur. J. Pharmacol. 491, 137-148.
    • (2004) Eur. J. Pharmacol. , vol.491 , pp. 137-148
    • De Vry, J.1    Kuhl, E.2    Franken-Kunkel, P.3    Eckel, G.4
  • 10
    • 0141738786 scopus 로고    scopus 로고
    • Intrathecal, but not intravenous adenosine reduces allodynia in patients with neuropathic pain
    • Eisenach J. C., Rauck R. L. and Curry R. (2003) Intrathecal, but not intravenous adenosine reduces allodynia in patients with neuropathic pain. Pain 105, 65-70.
    • (2003) Pain , vol.105 , pp. 65-70
    • Eisenach, J.C.1    Rauck, R.L.2    Curry, R.3
  • 11
    • 0025219160 scopus 로고
    • 1 receptors in rat brain, as revealed by autoradiography
    • 1 receptors in rat brain, as revealed by autoradiography. Neuroscience 34, 759-769.
    • (1990) Neuroscience , vol.34 , pp. 759-769
    • Fastbom, J.1    Fredholm, B.B.2
  • 12
    • 0346996805 scopus 로고    scopus 로고
    • 1 adenosine receptors increase receptor-G-protein coupling and counteract guanine nucleotide effects on agonist binding
    • 1 adenosine receptors increase receptor-G-protein coupling and counteract guanine nucleotide effects on agonist binding. Mol. Pharmacol. 64, 1557-1564.
    • (2003) Mol. Pharmacol. , vol.64 , pp. 1557-1564
    • Figler, H.1    Olsson, R.A.2    Linden, J.3
  • 13
    • 1842662390 scopus 로고    scopus 로고
    • Effects of the allosteric modulator SCH-202676 on adenosine and P2Y receptors
    • Gao Z.-G., Gross A. S. and Jacobson K. A. (2004) Effects of the allosteric modulator SCH-202676 on adenosine and P2Y receptors. Life Sci. 74, 3173-3180.
    • (2004) Life Sci. , vol.74 , pp. 3173-3180
    • Gao, Z.-G.1    Gross, A.S.2    Jacobson, K.A.3
  • 14
    • 0025829817 scopus 로고
    • Signal amplification in HL-60 granulocytes: Evidence that the chemotactic peptide receptor catalytically activates guanine-nucleotide-binding regulatory proteins in native plasma membranes
    • Gierschik P., Moghtader R., Straub C., Dieterich K. and Jakobs K. H. (1991) Signal amplification in HL-60 granulocytes: Evidence that the chemotactic peptide receptor catalytically activates guanine-nucleotide-binding regulatory proteins in native plasma membranes. Eur. J. Biochem. 197, 725-732.
    • (1991) Eur. J. Biochem. , vol.197 , pp. 725-732
    • Gierschik, P.1    Moghtader, R.2    Straub, C.3    Dieterich, K.4    Jakobs, K.H.5
  • 15
    • 0032877675 scopus 로고    scopus 로고
    • Intrathecal adenosine interacts with a spinal noradrenergic system to produce antinociception in nerve-injured rats
    • Gomes J. A., Li X. H., Pan H. L. and Eisenach J. C. (1999) Intrathecal adenosine interacts with a spinal noradrenergic system to produce antinociception in nerve-injured rats. Anesthesiology 91, 1072-1079.
    • (1999) Anesthesiology , vol.91 , pp. 1072-1079
    • Gomes, J.A.1    Li, X.H.2    Pan, H.L.3    Eisenach, J.C.4
  • 17
    • 0032995813 scopus 로고    scopus 로고
    • Exogenous and endogenous adenosine enhance the spinal antiallodynic effects of morphine in a rat model of neuropathic pain
    • Lavand'homme P. M. and Eisenach J. C. (1999) Exogenous and endogenous adenosine enhance the spinal antiallodynic effects of morphine in a rat model of neuropathic pain. Pain 80, 31-36.
    • (1999) Pain , vol.80 , pp. 31-36
    • Lavand'homme, P.M.1    Eisenach, J.C.2
  • 18
    • 0038814252 scopus 로고    scopus 로고
    • Allosteric adenosine receptor modulation reduces hypersensitivity following peripheral inflammation by a central mechanism
    • Li X., Conklin D., Pan H. L. and Eisenach J. C. (2003) Allosteric adenosine receptor modulation reduces hypersensitivity following peripheral inflammation by a central mechanism. J. Pharmacol. Exp. Ther. 305, 950-955.
    • (2003) J. Pharmacol. Exp. Ther. , vol.305 , pp. 950-955
    • Li, X.1    Conklin, D.2    Pan, H.L.3    Eisenach, J.C.4
  • 21
    • 0029915945 scopus 로고    scopus 로고
    • Interaction of full and partial agonists of the A1 adenosine receptor with receptor/ G protein complexes in rat brain membranes
    • Lorenzen A., Guerra L., Vogt H. and Schwabe U. (1996) Interaction of full and partial agonists of the A1 adenosine receptor with receptor/ G protein complexes in rat brain membranes. Mol. Pharmacol. 49, 915-926.
    • (1996) Mol. Pharmacol. , vol.49 , pp. 915-926
    • Lorenzen, A.1    Guerra, L.2    Vogt, H.3    Schwabe, U.4
  • 25
    • 1642499664 scopus 로고    scopus 로고
    • Synthesis and biological evaluation of 2,3,5-substituted [1,2,4]thiodiazoles as allosteric modulators of adenosine receptors
    • van dem Nieuwendijk A. M. C. H., Pietra D., Heitman L., Goblyos A. and Ijzerman A. P. (2004) Synthesis and biological evaluation of 2,3,5-substituted [1,2,4]thiodiazoles as allosteric modulators of adenosine receptors. J. Med. Chem. 47, 663-672.
    • (2004) J. Med. Chem. , vol.47 , pp. 663-672
    • Van Dem Nieuwendijk, A.M.C.H.1    Pietra, D.2    Heitman, L.3    Goblyos, A.4    Ijzerman, A.P.5
  • 26
    • 2142658682 scopus 로고    scopus 로고
    • Spinal adenosine receptor activation reduces hypersensitivity after surgery by a different mechanism than after nerve injury
    • Obata H., Li X. and Eisenach J. C. (2004) Spinal adenosine receptor activation reduces hypersensitivity after surgery by a different mechanism than after nerve injury. Anesthesiology 100, 1258-1262.
    • (2004) Anesthesiology , vol.100 , pp. 1258-1262
    • Obata, H.1    Li, X.2    Eisenach, J.C.3
  • 27
    • 0034899555 scopus 로고    scopus 로고
    • Allosteric adenosine modulation to reduce allodynia
    • Pan H. L., Zemin X., Leung E. and Eisenach J. C. (2001) Allosteric adenosine modulation to reduce allodynia. Anesthesiology 95, 416-420.
    • (2001) Anesthesiology , vol.95 , pp. 416-420
    • Pan, H.L.1    Zemin, X.2    Leung, E.3    Eisenach, J.C.4
  • 28
    • 0031017050 scopus 로고    scopus 로고
    • 35S]GTPγS binding in rat thalamus and cultured cell lines: Signal transduction mechanisms underlying agonist efficacy
    • 35S]GTPγS binding in rat thalamus and cultured cell lines: Signal transduction mechanisms underlying agonist efficacy. Mol. Pharmacol. 51, 87-96.
    • (1997) Mol. Pharmacol. , vol.51 , pp. 87-96
    • Selley, D.E.1    Sim, L.J.2    Xiao, R.3    Liu, Q.4    Childers, S.R.5
  • 32
    • 0030594567 scopus 로고    scopus 로고
    • Differences in G-protein activation by mu and delta-opioid, cannabinoid receptors in rat striatum
    • Sim L. J., Selley D. E., Xiao R. and Childers S. R. (1996b) Differences in G-protein activation by mu and delta-opioid, cannabinoid receptors in rat striatum. Eur. J. Pharmacol. 307, 97-105.
    • (1996) Eur. J. Pharmacol. , vol.307 , pp. 97-105
    • Sim, L.J.1    Selley, D.E.2    Xiao, R.3    Childers, S.R.4
  • 33
    • 0031594351 scopus 로고    scopus 로고
    • 35S]GTPγS binding in rat brain: Evidence for partial agonistactivity at mu opioid receptors
    • 35S]GTPγS binding in rat brain: Evidence for partial agonistactivity at mu opioid receptors. J. Neurochem. 70, 1567-1576.
    • (1998) J. Neurochem. , vol.70 , pp. 1567-1576
    • Sim, L.J.1    Liu, Q.X.2    Childers, S.R.3    Selley, D.E.4
  • 34
    • 0028986870 scopus 로고
    • 35S]thio) triphosphate binding to membranes from human neuroblastoma SH-SY5Y cells
    • 35S]thio) triphosphate binding to membranes from human neuroblastoma SH-SY5Y cells. Mol. Pharmacol. 47, 848-854.
    • (1995) Mol. Pharmacol. , vol.47 , pp. 848-854
    • Traynor, J.R.1    Nahorski, S.R.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.