-
1
-
-
8344227006
-
Adenosine diphosphate (ADP) does not induce thromboxane A2 generation in human platelets
-
Cattaneo M, Gachet C, Cazenave JP, Packham MA. Adenosine diphosphate (ADP) does not induce thromboxane A2 generation in human platelets. Blood 2002;99:3868-3869
-
(2002)
Blood
, vol.99
, pp. 3868-3869
-
-
Cattaneo, M.1
Gachet, C.2
Cazenave, J.P.3
Packham, M.A.4
-
3
-
-
0032493295
-
Coactivation of two different G protein-coupled receptors is essential for ADP-induced platelet aggregation
-
Jin J, Kunapuli SP. Coactivation of two different G protein-coupled receptors is essential for ADP-induced platelet aggregation. Proc Natl Acad Sci U S A 1998;95:8070-8074
-
(1998)
Proc Natl Acad Sci U S A
, vol.95
, pp. 8070-8074
-
-
Jin, J.1
Kunapuli, S.P.2
-
4
-
-
0031754497
-
Receptors for purines and pyrimidines
-
Ralevic V, Burnstock G. Receptors for purines and pyrimidines. Pharmacol Rev 1998;50:413-492
-
(1998)
Pharmacol Rev
, vol.50
, pp. 413-492
-
-
Ralevic, V.1
Burnstock, G.2
-
5
-
-
0030222204
-
Families of ion channels with two hydrophobic segments
-
North RA. Families of ion channels with two hydrophobic segments. Curr Opin Cell Biol 1996;8:474-483
-
(1996)
Curr Opin Cell Biol
, vol.8
, pp. 474-483
-
-
North, R.A.1
-
6
-
-
0028025001
-
New structural motif for ligand-gated ion channels defined by an ionotropic ATP receptor
-
Brake AJ, Wagenbach MJ, Julius D. New structural motif for ligand-gated ion channels defined by an ionotropic ATP receptor. Nature 1994;371:519-523
-
(1994)
Nature
, vol.371
, pp. 519-523
-
-
Brake, A.J.1
Wagenbach, M.J.2
Julius, D.3
-
7
-
-
0028030797
-
A new class of ligand-gated ion channel defined by P2x receptor for extracellular ATP
-
Valera S, Hussy N, Evans RJ, et al. A new class of ligand-gated ion channel defined by P2x receptor for extracellular ATP. Nature 1994;371:516-519
-
(1994)
Nature
, vol.371
, pp. 516-519
-
-
Valera, S.1
Hussy, N.2
Evans, R.J.3
-
8
-
-
0030614527
-
The P2Y1 receptor is an ADP receptor antagonized by ATP and expressed in platelets and megakaryoblastic cells
-
Leon C, Hechler B, Vial C, et al. The P2Y1 receptor is an ADP receptor antagonized by ATP and expressed in platelets and megakaryoblastic cells. FEBS Lett 1997;403:26-30
-
(1997)
FEBS Lett
, vol.403
, pp. 26-30
-
-
Leon, C.1
Hechler, B.2
Vial, C.3
-
9
-
-
0035843178
-
Identification of the platelet ADP receptor targeted by antithrombotic drugs
-
Hollopeter G, Jantzen HM, Vincent D, et al. Identification of the platelet ADP receptor targeted by antithrombotic drugs. Nature 2001;409:202-207
-
(2001)
Nature
, vol.409
, pp. 202-207
-
-
Hollopeter, G.1
Jantzen, H.M.2
Vincent, D.3
-
10
-
-
0035896562
-
ADP is the cognate ligand for the orphan G protein-coupled receptor SP1999
-
Zhang FL, Luo L, Gustafson E, et al. ADP is the cognate ligand for the orphan G protein-coupled receptor SP1999. J Biol Chem 2001;276:8608-8615
-
(2001)
J Biol Chem
, vol.276
, pp. 8608-8615
-
-
Zhang, F.L.1
Luo, L.2
Gustafson, E.3
-
11
-
-
0032495873
-
P2X1 purinoceptor in human platelets. Molecular cloning and functional characterization after heterologous expression
-
Sun B, Li J, Okahara K, Kambayashi J. P2X1 purinoceptor in human platelets. Molecular cloning and functional characterization after heterologous expression. J Biol Chem 1998;273: 11544-11547
-
(1998)
J Biol Chem
, vol.273
, pp. 11544-11547
-
-
Sun, B.1
Li, J.2
Okahara, K.3
Kambayashi, J.4
-
12
-
-
0032056369
-
The P2X1 receptor, an adenosine triphosphate-gated cation channel, is expressed in human platelets but not in human blood leukocytes
-
Clifford EE, Parker K, Humphreys BD, Kertesy SB, Dubyak GR. The P2X1 receptor, an adenosine triphosphate-gated cation channel, is expressed in human platelets but not in human blood leukocytes. Blood 1998;91:3172-3181
-
(1998)
Blood
, vol.91
, pp. 3172-3181
-
-
Clifford, E.E.1
Parker, K.2
Humphreys, B.D.3
Kertesy, S.B.4
Dubyak, G.R.5
-
13
-
-
0030608644
-
Presence of P2X1 purinoceptors in human platelets and megakaryoblastic cell lines
-
Vial C, Hechler B, Leon C, Cazenave JP, Cachet C. Presence of P2X1 purinoceptors in human platelets and megakaryoblastic cell lines. Thromb Haemost 1997;78:1500-1504
-
(1997)
Thromb Haemost
, vol.78
, pp. 1500-1504
-
-
Vial, C.1
Hechler, B.2
Leon, C.3
Cazenave, J.P.4
Cachet, C.5
-
14
-
-
0032567546
-
Identification of a P2X1 purinoceptor expressed on human platelets
-
Scase TJ, Heath MF, Allen JM, Sage SO, Evans RJ. Identification of a P2X1 purinoceptor expressed on human platelets. Biochem Biophys Res Commun 1998;242:525-528
-
(1998)
Biochem Biophys Res Commun
, vol.242
, pp. 525-528
-
-
Scase, T.J.1
Heath, M.F.2
Allen, J.M.3
Sage, S.O.4
Evans, R.J.5
-
15
-
-
0033821625
-
ADP is not an agonist at P2X(1) receptors: Evidence for separate receptors stimulated by ATP and ADP on human platelets
-
Mahaut-Smith MP, Ennion SJ, Rolf MG, Evans RJ. ADP is not an agonist at P2X(1) receptors: evidence for separate receptors stimulated by ATP and ADP on human platelets. Br J Pharmacol 2000;131:108-114
-
(2000)
Br J Pharmacol
, vol.131
, pp. 108-114
-
-
Mahaut-Smith, M.P.1
Ennion, S.J.2
Rolf, M.G.3
Evans, R.J.4
-
16
-
-
0032105512
-
The P2Y1 receptor is necessary for adenosine 5′-diphosphate-induced platelet aggregation
-
Hechler B, Leon C, Vial C, et al. The P2Y1 receptor is necessary for adenosine 5′-diphosphate-induced platelet aggregation. Blood 1998;92:152-159
-
(1998)
Blood
, vol.92
, pp. 152-159
-
-
Hechler, B.1
Leon, C.2
Vial, C.3
-
17
-
-
0032488890
-
Role of P2Y1 purinoceptor in ADP-induced platelet activation
-
Savi P, Beauverger P, Labouret C, et al. Role of P2Y1 purinoceptor in ADP-induced platelet activation. FEBS Lett 1998;422:291-295
-
(1998)
FEBS Lett
, vol.422
, pp. 291-295
-
-
Savi, P.1
Beauverger, P.2
Labouret, C.3
-
18
-
-
0031916728
-
Molecular basis for ADP-induced platelet activation. II. The P2Y1 receptor mediates ADP-induced intracellular calcium mobilization and shape change in platelets
-
Jin J, Daniel JL, Kunapuli SP. Molecular basis for ADP-induced platelet activation. II. The P2Y1 receptor mediates ADP-induced intracellular calcium mobilization and shape change in platelets. J Biol Chem 1998;273:2030-2034
-
(1998)
J Biol Chem
, vol.273
, pp. 2030-2034
-
-
Jin, J.1
Daniel, J.L.2
Kunapuli, S.P.3
-
19
-
-
0033955027
-
ADP can induce aggregation of human platelets via both P2Y(1) and P(2T) receptors
-
Jarvis GE, Humphries RG, Robertson MJ, Leff P. ADP can induce aggregation of human platelets via both P2Y(1) and P(2T) receptors. Br J Pharmacol 2000;129:275-282
-
(2000)
Br J Pharmacol
, vol.129
, pp. 275-282
-
-
Jarvis, G.E.1
Humphries, R.G.2
Robertson, M.J.3
Leff, P.4
-
20
-
-
0345368067
-
Ligand specificity and ticlopidine effects distinguish three human platelet ADP receptors
-
Geiger J, Honig-Liedl P, Schanzenbacher P, Walter U. Ligand specificity and ticlopidine effects distinguish three human platelet ADP receptors. Eur J Pharmacol 1998;351: 235-246
-
(1998)
Eur J Pharmacol
, vol.351
, pp. 235-246
-
-
Geiger, J.1
Honig-Liedl, P.2
Schanzenbacher, P.3
Walter, U.4
-
21
-
-
0031596463
-
P2Y1-receptors in human platelets which are pharmacologically distinct from P2Y(ADP)-receptors
-
Fagura MS, Dainty IA, McKay GD, et al. P2Y1-receptors in human platelets which are pharmacologically distinct from P2Y(ADP)-receptors. Br J Pharmacol 1998;124:157-164
-
(1998)
Br J Pharmacol
, vol.124
, pp. 157-164
-
-
Fagura, M.S.1
Dainty, I.A.2
McKay, G.D.3
-
22
-
-
0031914973
-
Molecular basis for ADP-induced platelet activation. I. Evidence for three distinct ADP receptors on human platelets
-
Daniel JL, Dangelmaier C, Jin J, et al. Molecular basis for ADP-induced platelet activation. I. Evidence for three distinct ADP receptors on human platelets. J Biol Chem 1998;273:2024-2029
-
(1998)
J Biol Chem
, vol.273
, pp. 2024-2029
-
-
Daniel, J.L.1
Dangelmaier, C.2
Jin, J.3
-
23
-
-
0032921133
-
Evidence for two distinct G-protein-coupled ADP receptors mediating platelet activation
-
Jantzen HM, Gousset L, Bhaskar V, et al. Evidence for two distinct G-protein-coupled ADP receptors mediating platelet activation. Thromb Haemost 1999;81:111-117
-
(1999)
Thromb Haemost
, vol.81
, pp. 111-117
-
-
Jantzen, H.M.1
Gousset, L.2
Bhaskar, V.3
-
24
-
-
0342723744
-
Defective platelet aggregation and increased resistance to thrombosis in purinergic P2Y(1) receptor-null mice
-
Leon C, Hechler B, Freund M, et al. Defective platelet aggregation and increased resistance to thrombosis in purinergic P2Y(1) receptor-null mice. J Clin Invest 1999; 104:1731-1737
-
(1999)
J Clin Invest
, vol.104
, pp. 1731-1737
-
-
Leon, C.1
Hechler, B.2
Freund, M.3
-
25
-
-
0032826036
-
Decreased platelet aggregation, increased bleeding time and resistance to thromboembolism in P2Y1-deficient mice
-
Fabre JE, Nguyen M, Latour A, et al. Decreased platelet aggregation, increased bleeding time and resistance to thromboembolism in P2Y1-deficient mice. Nat Med 1999; 5:1199-1202
-
(1999)
Nat Med
, vol.5
, pp. 1199-1202
-
-
Fabre, J.E.1
Nguyen, M.2
Latour, A.3
-
26
-
-
0026486964
-
Identification of a new congenital defect of platelet function characterized by severe impairment of platelet responses to adenosine diphosphate
-
Cattaneo M, Lecchi A, Randi AM, McGregor JL, Mannucci PM. Identification of a new congenital defect of platelet function characterized by severe impairment of platelet responses to adenosine diphosphate. Blood 1992;80:2787-2796
-
(1992)
Blood
, vol.80
, pp. 2787-2796
-
-
Cattaneo, M.1
Lecchi, A.2
Randi, A.M.3
McGregor, J.L.4
Mannucci, P.M.5
-
27
-
-
0033128384
-
The P2Y1 receptor is normal in a patient presenting a severe deficiency of ADP-induced platelet aggregation
-
Leon C, Vial C, Gachet C, et al. The P2Y1 receptor is normal in a patient presenting a severe deficiency of ADP-induced platelet aggregation. Thromb Haemost 1999;81:775-781
-
(1999)
Thromb Haemost
, vol.81
, pp. 775-781
-
-
Leon, C.1
Vial, C.2
Gachet, C.3
-
28
-
-
0034323126
-
Platelets from a patient heterozygous for the defect of P2CYC receptors for ADP have a secretion defect despite normal thromboxane A2 production and normal granule stores: Further evidence that some cases of platelet 'primary secretion defect' are heterozygous for a defect of P2CYC receptors
-
Cattaneo M, Lecchi A, Lombardi R, Gachet C, Zighetti ML. Platelets from a patient heterozygous for the defect of P2CYC receptors for ADP have a secretion defect despite normal thromboxane A2 production and normal granule stores: further evidence that some cases of platelet 'primary secretion defect' are heterozygous for a defect of P2CYC receptors. Arterioscler Thromb Vasc Biol 2000;20:E101-E106
-
(2000)
Arterioscler Thromb Vasc Biol
, vol.20
-
-
Cattaneo, M.1
Lecchi, A.2
Lombardi, R.3
Gachet, C.4
Zighetti, M.L.5
-
29
-
-
0030610096
-
Deficiency of (33P)2MeS-ADP binding sites on platelets with secretion defect, normal granule stores and normal thromboxane A2 production. Evidence that ADP potentiates platelet secretion independently of the formation of large platelet aggregates and thromboxane A2 production
-
Cattaneo M, Lombardi R, Zighetti ML, et al. Deficiency of (33P)2MeS-ADP binding sites on platelets with secretion defect, normal granule stores and normal thromboxane A2 production. Evidence that ADP potentiates platelet secretion independently of the formation of large platelet aggregates and thromboxane A2 production. Thromb Haemost 1997;77: 986-990
-
(1997)
Thromb Haemost
, vol.77
, pp. 986-990
-
-
Cattaneo, M.1
Lombardi, R.2
Zighetti, M.L.3
-
30
-
-
13044263119
-
A key role of adenosine diphosphate in the irreversible platelet aggregation induced by the PAR1-activating peptide through the late activation of phosphoinositide 3-kinase
-
Trumel C, Payrastre B, Plantavid M, et al. A key role of adenosine diphosphate in the irreversible platelet aggregation induced by the PAR1-activating peptide through the late activation of phosphoinositide 3-kinase. Blood 1999;94: 4156-4165
-
(1999)
Blood
, vol.94
, pp. 4156-4165
-
-
Trumel, C.1
Payrastre, B.2
Plantavid, M.3
-
31
-
-
0025264322
-
Released adenosine diphosphate stabilizes thrombin-induced human platelet aggregates
-
Cattaneo M, Canciani MT, Lecchi A, et al. Released adenosine diphosphate stabilizes thrombin-induced human platelet aggregates. Blood 1990;75:1081-1086
-
(1990)
Blood
, vol.75
, pp. 1081-1086
-
-
Cattaneo, M.1
Canciani, M.T.2
Lecchi, A.3
-
32
-
-
0002899125
-
Pharmacology of ticlopidine and clopidogrel
-
Savi P, Herbert JM. Pharmacology of ticlopidine and clopidogrel. Haematologica 2000;85:73-77
-
(2000)
Haematologica
, vol.85
, pp. 73-77
-
-
Savi, P.1
Herbert, J.M.2
-
33
-
-
0002494462
-
Pharmacology of AR-C69931MX and related compounds: From pharmacological tools to clinical trials
-
Humphries RG. Pharmacology of AR-C69931MX and related compounds: from pharmacological tools to clinical trials. Haematologica 2000;85:66-72
-
(2000)
Haematologica
, vol.85
, pp. 66-72
-
-
Humphries, R.G.1
-
34
-
-
0036713665
-
Effects of enhanced P2X1 receptor Ca2+ influx on functional responses in human platelets
-
Rolf MG, Mahaut-Smith MP. Effects of enhanced P2X1 receptor Ca2+ influx on functional responses in human platelets. Thromb Haemost 2002;88:495-502
-
(2002)
Thromb Haemost
, vol.88
, pp. 495-502
-
-
Rolf, M.G.1
Mahaut-Smith, M.P.2
-
35
-
-
0035164358
-
The ATP-gated P2X1 ion channel acts as a positive regulator of platelet responses to collagen
-
Oury C, Toth-Zsamboki E, Thys C, et al. The ATP-gated P2X1 ion channel acts as a positive regulator of platelet responses to collagen. Thromb Haemost 2001;86:1264-1271
-
(2001)
Thromb Haemost
, vol.86
, pp. 1264-1271
-
-
Oury, C.1
Toth-Zsamboki, E.2
Thys, C.3
-
36
-
-
4043133496
-
The P2X1 receptor for ATP plays an essential role in platelet aggregation at high shear
-
abst
-
Cattaneo M, Marchese P, Jacobson KA, Ruggeri ZM. The P2X1 receptor for ATP plays an essential role in platelet aggregation at high shear. Haematology J. 2003;4(suppl 2): 150 (abst)
-
(2003)
Haematology J.
, vol.4
, Issue.SUPPL. 2
, pp. 150
-
-
Cattaneo, M.1
Marchese, P.2
Jacobson, K.A.3
Ruggeri, Z.M.4
-
37
-
-
0042422021
-
A role of the fast ATP-gated P2X1 cation channel in thrombosis of small arteries in vivo
-
Hechler B, Lenain N, Marchese P, et al. A role of the fast ATP-gated P2X1 cation channel in thrombosis of small arteries in vivo. J Exp Med 2003;198:661-667
-
(2003)
J Exp Med
, vol.198
, pp. 661-667
-
-
Hechler, B.1
Lenain, N.2
Marchese, P.3
-
38
-
-
0028819883
-
Purinoceptors on blood platelets: Further pharmacological and clinical evidence to suggest the presence of two ADP receptors
-
Gachet C, Cattaneo M, Ohlmann P, et al. Purinoceptors on blood platelets: further pharmacological and clinical evidence to suggest the presence of two ADP receptors. Br J Haematol 1995;91:434-444
-
(1995)
Br J Haematol
, vol.91
, pp. 434-444
-
-
Gachet, C.1
Cattaneo, M.2
Ohlmann, P.3
-
39
-
-
79960971649
-
Unique mutations in the P2Y12 locus of patients with previously described defects in ADP-dependent aggregation
-
Conley PB, Jurek MM, Vincent D, Lecchi A, Cattaneo M. Unique mutations in the P2Y12 locus of patients with previously described defects in ADP-dependent aggregation. Blood 2001;98:43b (abst)
-
(2001)
Blood
, vol.98
-
-
Conley, P.B.1
Jurek, M.M.2
Vincent, D.3
Lecchi, A.4
Cattaneo, M.5
-
40
-
-
0028942659
-
An inherited bleeding disorder linked to a defective interaction between ADP and its receptor on platelets. Its influence on glycoprotein IIb-IIIa complex function
-
Nurden P, Savi P, Heilmann E, et al. An inherited bleeding disorder linked to a defective interaction between ADP and its receptor on platelets. Its influence on glycoprotein IIb-IIIa complex function. J Clin Invest 1995;95:1612-1622
-
(1995)
J Clin Invest
, vol.95
, pp. 1612-1622
-
-
Nurden, P.1
Savi, P.2
Heilmann, E.3
-
41
-
-
79960971724
-
Phenotypic and genotypic characterization of a congenital bleeding disorder caused by a dysfunctional P2Y12 ADP receptor
-
abst
-
Cattaneo M, Zighetti ML, Lombardi R, et al. Phenotypic and genotypic characterization of a congenital bleeding disorder caused by a dysfunctional P2Y12 ADP receptor. Blood 2001; 98:443a (abst)
-
(2001)
Blood
, vol.98
-
-
Cattaneo, M.1
Zighetti, M.L.2
Lombardi, R.3
-
42
-
-
0033596870
-
Role of the extracellular loops of G protein-coupled receptors in ligand recognition: A molecular modeling study of the human P2Y1 receptor
-
Moro S, Hoffmann C, Jacobson KA. Role of the extracellular loops of G protein-coupled receptors in ligand recognition: a molecular modeling study of the human P2Y1 receptor. Biochemistry 1999;38:3498-3507
-
(1999)
Biochemistry
, vol.38
, pp. 3498-3507
-
-
Moro, S.1
Hoffmann, C.2
Jacobson, K.A.3
-
43
-
-
0032559887
-
Human P2Y1 receptor: Molecular modeling and site-directed mutagenesis as tools to identify agonist and antagonist recognition sites
-
Moro S, Guo D, Camaioni E, et al. Human P2Y1 receptor: molecular modeling and site-directed mutagenesis as tools to identify agonist and antagonist recognition sites. J Med Chem 1998;41:1456-1466
-
(1998)
J Med Chem
, vol.41
, pp. 1456-1466
-
-
Moro, S.1
Guo, D.2
Camaioni, E.3
-
44
-
-
0035724598
-
Patients with congenital abnormality of platelet aggregation induced by Ca(2+) ionophores may have a defect of the platelet P2Y(12) receptor for ADP
-
Cattaneo M, Lecchi A. Patients with congenital abnormality of platelet aggregation induced by Ca(2+) ionophores may have a defect of the platelet P2Y(12) receptor for ADP. Br J Haematol 2001;115:485-487
-
(2001)
Br J Haematol
, vol.115
, pp. 485-487
-
-
Cattaneo, M.1
Lecchi, A.2
-
45
-
-
0028090198
-
Role of ADP in platelet aggregation at high shear: Studies in a patient with congenital defect of platelet responses to ADP
-
Cattaneo M, Zighetti ML, Lombardi R, Mannucci PM. Role of ADP in platelet aggregation at high shear: studies in a patient with congenital defect of platelet responses to ADP. Br J Haematol 1994;88:826-829
-
(1994)
Br J Haematol
, vol.88
, pp. 826-829
-
-
Cattaneo, M.1
Zighetti, M.L.2
Lombardi, R.3
Mannucci, P.M.4
-
46
-
-
0002251640
-
Congenital deficiency of the phospholipase mC coupled platelet P2Y1 receptor leads to a mild bleeding disorder
-
abst
-
Oury C, Lenaerts T, Peerlinck K, Vermylen J, Hoylaerts MF. Congenital deficiency of the phospholipase mC coupled platelet P2Y1 receptor leads to a mild bleeding disorder. Thromb Haemost 1999;85(suppl):20 (abst)
-
(1999)
Thromb Haemost
, vol.85
, Issue.SUPPL.
, pp. 20
-
-
Oury, C.1
Lenaerts, T.2
Peerlinck, K.3
Vermylen, J.4
Hoylaerts, M.F.5
-
47
-
-
0034725571
-
A natural dominant negative P2X1 receptor due to deletion of a single amino acid residue
-
Oury C, Toth-Zsamboki E, Van Geet C, et al. A natural dominant negative P2X1 receptor due to deletion of a single amino acid residue. J Biol Chem 2000;275:22611-22614
-
(2000)
J Biol Chem
, vol.275
, pp. 22611-22614
-
-
Oury, C.1
Toth-Zsamboki, E.2
Van Geet, C.3
|