Ca2+ sensitization and the regulation of contractility in rat anococcygeus and retractor penis muscle

Biochemical Pharmacology

Volumn 69, Issue 10, 2005, Pages 1483-1492

  Teixeira, Cleber E ^a   Jin, Liming ^a   Ying, Zhekang ^a   Palmer, Trenis ^a   Webb, R Clinton ^a  

^a MEDICAL COLLEGE OF GEORGIA   (United States)

Author keywords

Anococcygeus muscle; Ca 2+ sensitization; Retractor penis muscle; Rho kinase; RhoA; RhoGEFs

Indexed keywords

(5 ISOQUINOLINESULFONYL)HOMOPIPERAZINE; 2 METHYL 1 [(4 METHYL 5 ISOQUINOLINYL)SULFONYL]HOMOPIPERAZINE; BRETYLIUM TOSYLATE; CALCIUM SENSITIZER; CARBACHOL; CYCLOHEXANE DERIVATIVE; N (4 PYRIDYL) 4 (1 AMINOETHYL)CYCLOHEXANECARBOXAMIDE; NORADRENALIN; PHENTOLAMINE; PHENYLEPHRINE; PIPERAZINE DERIVATIVE; POTASSIUM CHLORIDE; RHO KINASE; RHO KINASE A; RHO KINASE ALPHA; RHO KINASE BETA; RHO KINASE INHIBITOR; TETRODOTOXIN; UNCLASSIFIED DRUG; CALCIUM; GUANINE NUCLEOTIDE EXCHANGE FACTOR; PROTEIN SERINE THREONINE KINASE; RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR P115; RHO-ASSOCIATED KINASE; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; SIGNAL PEPTIDE;

ANIMAL TISSUE; ANOCOCCYGEUS MUSCLE; ARTICLE; BIOACCUMULATION; CONTROLLED STUDY; DEPOLARIZATION; DRUG ANTAGONISM; ELECTROSTIMULATION; ENZYME SUBUNIT; EVOKED RESPONSE; MALE; MUSCLE TISSUE; NONHUMAN; PENIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SENSITIZATION; SMOOTH MUSCLE CONTRACTILITY; SMOOTH MUSCLE RELAXATION; STATISTICAL SIGNIFICANCE; ANIMAL; METABOLISM; MUSCLE CONTRACTION; PHYSIOLOGY; SIGNAL TRANSDUCTION; SPRAGUE DAWLEY RAT;

ANIMALS; CALCIUM; ELECTRIC STIMULATION; GUANINE NUCLEOTIDE EXCHANGE FACTORS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MALE; MUSCLE CONTRACTION; PENIS; PROTEIN-SERINE-THREONINE KINASES; RATS; RATS, SPRAGUE-DAWLEY; RHOA GTP-BINDING PROTEIN; SIGNAL TRANSDUCTION;

EID: 18044366013     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bcp.2005.02.018     Document Type: Article

References (40)

1. A.P. Somlyo, and A.V. Somlyo Signal transduction and regulation in smooth muscle Nature 372 1994 231 236
2. R.C. Webb Smooth muscle contraction and relaxation Adv Physiol Educ 27 2003 201 206
3. O. Ogut, and F.V. Brozovich Regulation of force in vascular smooth muscle J Mol Cell Cardiol 35 2003 347 355
4. 2+ sensitivity of smooth muscle and nonmuscle myosin II: modulated by G proteins, kinases, and myosin phosphatase Physiol Rev 83 2003 1325 1358
5. K. Chitaley, C.J. Wingard, R.C. Webb, H. Branan, V.S. Stopper, and R.W. Lewis Antagonism of Rho-kinase stimulates rat penile erection via a nitric oxide-independent pathway Nat Med 7 2001 119 122
6. R.W. Rees, D.J. Ralph, M. Royle, S. Moncada, and S. Cellek Y-27632, an inhibitor of Rho-kinase, antagonizes noradrenergic contractions in the rabbit and human penile corpus cavernosum Br J Pharmacol 133 2001 455 458
7. 2+ sensitization in erectile function J Biol Chem 277 2002 30614 30621
8. A. Wibberley, Z. Chen, E. Hu, J.P. Hieble, and T.D. Westfall Expression and functional role of Rho-kinase in rat urinary bladder smooth muscle Br J Pharmacol 138 2003 757 766
9. P.H. Ratz, J.T. Meehl, and T.J. Eddinger RhoA kinase and protein kinase C participate in regulation of rabbit stomach fundus smooth muscle contraction Br J Pharmacol 137 2002 983 992
10. K. Swärd, M. Mita, D.P. Wilson, J.T. Deng, M. Susnjar, and M.P. Walsh The role of RhoA and Rho-associated kinase in vascular smooth muscle contraction Curr Hypertens Rep 5 2003 66 72
11. S. Kupittayanant, T. Burdyga, and S. Wray The effects of inhibiting Rho-associated kinase with Y-27632 on force and intracellular calcium in human myometrium Pflügers Arch 443 2001 112 114
12. 2+ sensitization Am J Respir Cell Mol Biol 20 1999 1190 1200
13. N. Wettschureck, and S. Offermanns Rho/Rho-kinase mediated signaling in physiology and pathophysiology J Mol Med 80 2002 629 638
14. K. Riento, and A.J. Ridley Rocks: multifunctional kinases in cell behaviour Nat Rev Mol Cell Biol 4 2003 446 456
15. E.M. Ross, and T.M. Wilkie GTPase-activating proteins for heterotrimeric G proteins: regulators of G protein signaling (RGS) and RGS-like proteins Annu Rev Biochem 69 2000 795 827
16. S. Fukuhara, H. Chikumi, and J.S. Gutkind RGS-containing Rho-GEFs: the missing link between transforming G proteins and Rho? Oncogene 20 2001 1661 1668
17. K. Longenecker, M.E. Lewis, H. Chikumi, J.S. Gutkind, and Z.S. Derewenda Structure of the RGS-like domain from PDZ-RhoGEF: linking heterotrimeric G protein-coupled signaling to Rho GTPases Structure 9 2001 559 569
18. A. Schmidt, and A. Hall Guanine nucleotide exchange factors for Rho GTPases: turning on the switch Genes Dev 16 2002 1587 1609
19. K. Kimura, M. Ito, M. Amano, K. Chihara, Y. Fukata, and M. Nakafuku Regulation of myosin phosphatase by Rho and Rho-associated kinase (Rho-kinase) Science 273 1996 245 248
20. Y. Kureishi, S. Kobayashi, M. Amano, K. Kimura, H. Kanaide, and T. Nakano Rho-associated kinase directly induces smooth muscle contraction through myosin light chain phosphorylation J Biol Chem 272 1997 12257 12260
21. M. Uehata, T. Ishizaki, H. Satoh, T. Ono, T. Kawahara, and T. Morishita Calcium sensitization of smooth muscle mediated by a Rho-associated protein kinase in hypertension Nature 389 1997 990 994
22. S.P. Davies, H. Reddy, M. Caivano, and P. Cohen Specificity and mechanism of action of some commonly used protein kinase inhibitors Biochem J 351 2000 95 105
23. Y. Sasaki, M. Suzuki, and H. Hidaka The novel and specific Rho-kinase inhibitor (S)-(+)-2-methyl-1-[(4-methyl-5-isoquinoline)sulfonyl]-homopiperazine as a probing molecule for Rho-kinase-involved pathway Pharmacol Ther 93 2002 225 232
24. J.S. Gillespie The rat anococcygeus muscle and its response to nerve stimulation and to some drugs Br J Pharmacol 45 1972 404 416
25. W.G. Dail, Y. Carrillo, and G. Walton Innervation of the anococcygeus muscle of the rat Cell Tissue Res 259 1990 139 146
26. E. Klinge, P. Pohto, and E. Solatunturi Adrenergic innervation and structure of bull retractor penis muscle Acta Physiol Scand 78 1970 110 116
27. E. Klinge, and N.O. Sjöstrand Contraction and relaxation of the retractor penis muscle and the penile artery of the bull Acta Physiol Scand 420 1974 1 88
28. H. Sheng, H.H. Schmidt, M. Nakane, J.A. Mitchell, J.S. Pollock, and U. Föstermann Characterization and localization of nitric oxide synthase in non-adrenergic non-cholinergic nerves from bovine retractor penis muscles Br J Pharmacol 106 1992 768 773
29. C.G. Li, and M.J. Rand Effects of hydroxocobalamin and carboxy-PTIO on nitrergic transmission in porcine anococcygeus and retractor penis muscles Br J Pharmacol 127 1999 172 176
30. S. Ayman, P. Wallace, C.P. Wayman, A. Gibson, and I. McFadzean Receptor-independent activation of Rho-kinase-mediated calcium sensitisation in smooth muscle Br J Pharmacol 139 2003 1532 1538
31. Z. Ying, L. Jin, A.M. Dorrance, and R.C. Webb Increased expression of mRNA for regulator of G protein signaling domain-containing Rho guanine nucleotide exchange factors in aorta from stroke-prone spontaneously hypertensive rats Am J Hypertens 17 2004 981 985
32. T. Leung, E. Manser, L. Tan, and L. Lim A novel serine/threonine kinase binding the Ras-related RhoA GTPase which translocates the kinase to peripheral membranes J Biol Chem 270 1995 29051 29054
33. T. Ishizaki, M. Maekawa, K. Fujisawa, K. Okawa, A. Iwamatsu, and A. Fujita The small GTP-binding protein Rho binds to and activates a 160 kDa Ser/Thr protein kinase homologous to myotonic dystrophy kinase EMBO J 15 1996 1885 1893
34. M.J. Hart, S. Sharma, N. elMasry, R.G. Qiu, P. McCabe, and P. Polakis Identification of a novel guanine nucleotide exchange factor for the Rho GTPase J Biol Chem 271 1996 25452 25458
35. S. Fukuhara, C. Murga, M. Zohar, T. Igishi, and J.S. Gutkind A novel PDZ domain containing guanine nucleotide exchange factor links heterotrimeric G proteins to Rho J Biol Chem 274 1999 5868 5879
36. P.J. Kourlas, M.P. Strout, B. Becknell, M.L. Veronese, C.M. Croce, and K.S. Theil Identification of a gene at 11q23 encoding a guanine nucleotide exchange factor: evidence for its fusion with MLL in acute myeloid leukaemia Proc Natl Acad Sci USA 97 2000 2145 2150
37. αq/11 in the contractile signal transduction pathway of muscarinic M3 receptors in caecal smooth muscle Eur J Pharmacol 315 1996 213 219
38. 1-adrenoceptor subtype-mediated responses in Fischer 344 rat aorta Mol Pharmacol 52 1997 1064 1070
39. M. Mita, H. Yanagihara, S. Hishinuma, M. Saito, and M.P. Walsh Membrane depolarization-induced contraction of rat caudal arterial smooth muscle involves Rho-associated kinase Biochem J 364 2002 431 440
40. P. Ghisdal, G. Vandenberg, and N. Morel Rho-dependent kinase is involved in agonist-activated calcium entry in rat arteries J Physiol 551 2003 855 867