Involvement of G(αq/11) in the contractile signal transduction pathway of muscarinic M3 receptors in caecal smooth muscle

European Journal of Pharmacology

Volumn 315, Issue 2, 1996, Pages 213-219

  Cuq, Pierre ^a   Zumbihl, Robert ^b   Fischer, Thierry ^b   Rouot, Bruno ^b   Bali, Jean Pierre ^a   Magous, Richard ^a  

^a UNIV MONTPELLIER   (France)

^b INSERM   (France)

Author keywords

Antibody; Contraction; G protein; Muscarinic; Phospholipase C; Smooth muscle

Indexed keywords

CARBACHOL; GUANINE NUCLEOTIDE BINDING PROTEIN; MEMBRANE PROTEIN; MUSCARINIC M3 RECEPTOR;

ANIMAL TISSUE; ARTICLE; CECUM; CONTROLLED STUDY; IMMUNOBLOTTING; IMMUNOCYTOCHEMISTRY; IN VITRO STUDY; MALE; NONHUMAN; PRIORITY JOURNAL; RABBIT; SIGNAL TRANSDUCTION; SMOOTH MUSCLE CONTRACTION;

ANIMALS; ANTIBODIES; CARBACHOL; CECUM; ENZYME ACTIVATION; GTP-BINDING PROTEINS; MALE; MUSCARINIC AGONISTS; MUSCLE CONTRACTION; MUSCLE, SMOOTH; PHOSPHOLIPASE C; RABBITS; RECEPTORS, MUSCARINIC; SIGNAL TRANSDUCTION;

EID: 0030583726     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-2999(96)00605-X     Document Type: Article

References (41)

1. Ashkenazi, A., E.G. Peralta, J.W. Winslow, J. Ramachandran and D.J. Capon, 1989, Functionally distinct G proteins selectively couple different receptors to PI hydrolysis in the same cell, Cell 56, 487.
2. Barocelli, M., M. Chiavarini, V. Ballabeni, F. Bordi and M. Impicciatore, 1993, Interaction of selective compounds with muscarinic receptors at dispersed intestinal smooth muscle cells, Br. J. Pharmacol. 108, 393.
3. q/11, and phospholipase C-β1, J. Biol. Chem. 267, 8081.
4. Birnbaumer, L., J. Abramowitz and A.M. Brown, 1990, Receptor-effector coupling by G proteins, Biochim. Biophys. Acta 1031, 163.
5. 2+ mobilization in isolated guinea-pig and human gastric smooth muscle cells, J. Biol. Chem. 261, 16591.
6. Bonner, T.I., 1989, The molecular basis of muscarinic receptor diversity, Trends Neurosci. 12, 148.
7. Boyer, J.L., A. Paterson and T.K. Harden, 1994, G-protein-mediated regulation of phospholipase C: involvement of βγ subunits, Trends Cardiovasc. Med. 4, 88.
8. Buckley, N.J., T.I. Bonner and M.R. Brann, 1989, Antagonist binding properties of five cloned muscarinic receptors expressed in CHO-K1 cells, Mol. Pharmacol. 35, 469.
9. Bursten, S.L., W.E. Harris, K. Bomszty and D. Lovett, 1991, Interleukin-1 rapidly stimulates lysophosphatidate acyltransferase and phosphatidate phosphohydrolase activities in human mesanglial cells, J. Biol. Chem. 266, 20732.
10. Candell, L.M., S.H. Yun, L.L.P. Tran and F.J. Ehlert, 1990, Differential coupling of subtypes of the muscarinic receptors to adenylate cyclase and phosphoinositide hydrolysis in the longitudinal muscle of the rat ileum, Mol. Pharmacol. 38, 689.
11. Cuq, P., R. Magous and J.P. Bali, 1994a, Pharmacological coupling and functional role for the muscarinic receptor subtypes in isolated cells from the circular smooth muscle of the rabbit cecum, J. Pharmacol. Exp. Ther. 271, 149.
12. Cuq, P., R. Magous and J.P. Bali, 1994b, Signal transduction pathways of muscarinic receptors in circular smooth muscle from the rabbit caecum, Mol. Cell. Biochem. 140, 65.
13. αi3 in chinese hamster ovary cells. Activation and desensitization of the phospholipase C signaling pathways, J. Biol. Chem. 268, 5676.
14. Dörje, F., T. Friebe, R. Tacke, E. Mutschler and G. Lambrecht, 1990, Novel pharmacological profile of muscarinic receptors mediating contraction of the guinea-pig uterus, Naunyn-Schmiedeberg's Arch. Pharmacol. 342, 284-289.
15. Eglen, R.M., H. Reddy, N. Watson and R.A.J. Challiss, 1994, Muscarinic acetylcholine receptor subtypes in smooth muscle, Trends Pharmacol. Sci. 15, 114.
16. Felder, C.C., 1995, Muscarinic acetylcholine receptors: signal transduction through multiple effectors, FASEB J. 9, 619.
17. Felder, C.C., A.L. Ma and B.R. Conklin, 1989, Carbachol-induced reverse transformation of Chinese hamster ovary cells transfected with and expressing the m5 muscarinic acetylcholine receptor, FEBS Lett. 245, 75.
18. Gomez, A., F. Martos, I. Bellido, E. Marquez, A.J. Garcia, J. Pavia and F. Sanchez De La Cuesta, 1992, Muscarinic receptor subtypes in human and rat colon smooth muscle, Biochem. Pharmacol. 43, 2413.
19. 2 muscarinic receptors in rat intestinal smooth muscle, J. Pharmacol. Exp. Ther. 263, 221.
20. Hulme, E.C., N.J.M. Birdsall and N.J. Buckley, 1990, Muscarinic receptor subtypes, Annu. Rev. Pharmacol. Toxicol. 30, 633.
21. 11 G proteins with actin filaments in WRK1 cells: relation to G protein-mediated phospholipase C activation, Proc. Natl. Acad. Sci. USA 92, 8413.
22. Lazareno, S., T. Farries and N.J.M. Birdsall, 1993, Pharmacological characterization of guanine nucleotide exchange reactions in membranes from CHO cells stably transacted with human muscarinic receptor M1-M4, Life Sci. 52, 449.
23. Maeda, A., T. Kubo, M. Mishima and S. Numa, 1988, Tissue distribution of mRNAs encoding muscarinic acetylcholine receptor subtypes, FEBS Lett. 239, 339.
24. Makhlouf, G.M, 1987, Isolated smooth muscle cells of the gut, in: Physiology of the Gastrointestinal Tract. 2nd Ed., ed. L.R. Johnson (Raven, New York) p. 555.
25. Milligan, G, 1994, Specificity and functional applications of antipeptide antisera which identify G-protein α subunits, in: Methods in Enzymology, 237, ed. R. Iyengar (Academic Press) p. 268.
26. Mousli, M., C. Bronner, J. Bockaert, B. Rouot and Y. Landry, 1990, Interaction of substance P, compound 48/80 and mastoparan with the α-subunit C-terminus of G-protein, Immunol. Lett. 25, 355.
27. 2+ mobilization in circular but not longitudinal muscle cells of intestine, Am. J. Physiol. 261, G937.
28. Nathanson, N.M., 1987, Molecular properties of the muscarinic acetylcholine receptor, Annu. Rev. Neurosci. 10, 195.
29. Padrell, E., D.J. Carty, T.M. Moriarty, J.D. Hildebrandt, E.M. Landau and R. Iyengar, 1991, Two forms of the bovine brain Go that stimulate the inositol trisphosphate-mediated C1-currents in Xenopus oocytes. Distinct guanine nucleotides binding properties, J. Biol. Chem. 266, 9771.
30. Parker, E.M., K. Kameyama, T. Higashijima and E.M. Ross, 1991, Reconstitutively active G protein-coupled receptors purified from baculovirus-infected insect cell, J. Biol. Chem. 266, 519.
31. Peralta, E.G., A. Ashkenazi, J.W. Winslow, J. Ramachandran and D.J. Capon, 1988, Differential regulation of PI hydrolysis and adenylyl cyclase by muscarinic receptor subtypes, Nature (London) 334, 434.
32. αq/11 in m3-muscarinic receptor stimulation of phosphatidylinositol 4,5 bisphosphate-specific phospholipase C in rat parotid gland membranes, Arch. Biochem. Biophys. 305, 546.
33. Sternweis, P.C. and A.V. Smrcka, 1992, Regulation of phospholipase C by G proteins, Trends Biochem. Sci. 17, 502.
34. 2 muscarinic receptor in smooth muscle of guinea-pig ileum, Mol. Pharmacol. 44, 102.
35. 3-mediated contractions and phosphoinositides hydrolysis, J. Pharmacol. Exp. Ther. 271, 1042.
36. oα immunoreactivity in both plasma and granule membranes of chromaffin cells, FEBS Lett. 215, 339.
37. Wilkie, T.M., D.J. Gilbert, A.S. Olsen, X.N. Chen, T.T. Amatruda, J.R. Korenberg, B.J. Trask, P. De Jong, R.R. Reed, M.I. Simon, N.A. Jenkins and N.G. Copeland, 1992, Evolution of the mammalian G protein α subunit multigene family, Nat. Genet. 1, 85.
38. Zhang, L. and I.L.O. Buxton, 1991, Muscarinic receptors in canine colonic circular smooth muscle. II. Signal transduction pathways, Mol. Pharmacol. 40, 352.
39. 3 subtypes, Mol. Pharmacol. 40, 343.
40. qα, in bovine iris sphincter membranes: characteristics of the phospholipase and its coupling to cholinergic muscarinic receptors, Exp. Eye Res. 59, 377.
41. o2α isoforms in human myometrium, Eur. J. Pharmacol. Mol. Pharmacol. Sect. 288, 9.