Binding of the initiation factor σ70 to core RNA polymerase is a multistep process

Molecular Cell

Volumn 8, Issue 1, 2001, Pages 21-31

  Gruber, Tanja M ^a   Markov, Dmitriy ^c   Sharp, Meghan M ^b   Young, Brian A ^b   Lu, Chi Zen ^a   Zhong, Hong Ji ^a   Artsimovitch, Irina ^d   Geszvain, Katherine M ^d   Arthur, Terrance M ^d   Burgess, Richard R ^d   Landick, Robert ^d   Severinov, Konstantin ^c   Gross, Carol A ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c RUTGERS UNIVERSITY   (United States)

^d UNIVERSITY OF WISCONSIN MADISON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

INITIATION FACTOR; INITIATION FACTOR SIGMA; RNA POLYMERASE; UNCLASSIFIED DRUG;

ARTICLE; ESCHERICHIA COLI; MUTATION; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION; TRANSCRIPTION INITIATION;

ESCHERICHIA COLI;

EID: 17944375388     PISSN: 10972765     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1097-2765(01)00292-1     Document Type: Article

References (43)

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2. Mutational analysis of beta′ 260-309, a sigma 70 binding site located on Escherichia coli core RNA polymerase
3. Protein-DNA assemblies controlling lytic development of bacteriophage Mu
4. A mutation in region 1.1 of sigma70 affects promoter DNA binding by Escherichia coli RNA polymerase holoenzyme
5. Conformational changes of Escherichia coli RNA polymerase sigma70 factor induced by binding to the core enzyme
6. Core RNA polymerase from E. coli induces a major change in the domain arrangement of the sigma 70 subunit
7. DNA footprints of the two kinetically significant intermediates in formation of an RNA polymerase-promoter open complex: Evidence that interactions with start site and downstream DNA induce sequential conformational changes in polymerase and DNA
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14. Yeast RNA polymerase II at 5 A resolution
15. 70 subunit of RNA polymerase with altered promoter specificity
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21. Use of in vitro protein synthesis from polymerase chain reaction-generated templates to study interaction of Escherichia coli transcription factors with core RNA polymerase and for epitope mapping of monoclonal antibodies
22. 70 family: Sequence conservation and evolutionary relationships
23. Crystal structure of a sigma 70 subunit fragment from E. coli RNA polymerase
24. Promoter recognition as measured by binding of polymerase to nontemplate strand oligonucleotide
25. RNA polymerase unveiled
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32. The σ subunit conserved region 3 is part of the "5′-face" of active center of Escherichia coli RNA polymerase
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34. Domain organization of the Escherichia coli RNA polymerase sigma 70 subunit
35. The interface of sigma with core RNA polymerase is extensive, conserved, and functionally specialized
36. Mutations in rpoD, the gene encoding the sigma 70 subunit of Escherichia coli RNA polymerase, that increase expression of the lac operon in the absence of CAP-cAMP
37. Single-step purification of polypeptides expressed in Escherichia coli as fusions with glutathione S-transferase
38. Allosteric control of RNA polymerase by a site that contacts nascent RNA hairpins
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42. 70
43. Crystal structure of Thermus aquaticus core RNA polymerase at 3.3 A resolution