Nuclear import of the histone acetyltransferase complex SAS-I in Saccharomyces cerevisiae

Journal of Cell Science

Volumn 118, Issue 7, 2005, Pages 1473-1484

  Schaper, Sigrid ^a   Franke, Jacqueline ^a   Meijsing, Sebastiaan H ^a,b   Ehrenhofer Murray, Ann E ^a  

^a MAX PLANCK INSTITUTE FOR MOLECULAR GENETICS   (Germany)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Importin karyopherin; KAP123; SAS2; Silencing

Indexed keywords

HISTONE ACETYLTRANSFERASE; KARYOPHERIN;

ACETYLATION; AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; CHROMATIN; CONSENSUS SEQUENCE; CONTROLLED STUDY; DATA BASE; ENZYME ACTIVITY; ENZYME SUBSTRATE; ENZYME SUBUNIT; GENE DELETION; IN VIVO STUDY; NONHUMAN; NUCLEAR IMPORT; NUCLEAR LOCALIZATION SIGNAL; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN DOMAIN; SACCHAROMYCES CEREVISIAE; SEQUENCE ALIGNMENT; SIGNAL TRANSDUCTION;

ACETYLTRANSFERASES; ACTIVE TRANSPORT, CELL NUCLEUS; CARRIER PROTEINS; CELL NUCLEUS; GREEN FLUORESCENT PROTEINS; HISTONE ACETYLTRANSFERASES; MEMBRANE TRANSPORT PROTEINS; MULTIENZYME COMPLEXES; RECEPTORS, CYTOPLASMIC AND NUCLEAR; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; SIGNAL TRANSDUCTION;

EID: 17844387387     PISSN: 00219533     EISSN: None     Source Type: Journal    
DOI: 10.1242/jcs.01739     Document Type: Article

References (38)

1. Adams, A., Gottsching, D. E., Kaiser, C. A. and Stearns, T. (1997). Methods in Yeast Genetics: a Laboratory Course Manual Cold Spring Harbor Laboratory Press, Cold Spring Harbor, New York.
2. Baudin-Baillieu, A., Guillemet, E., Cullin, C. and Lacroute, F. (1997). Construction of a yeast strain deleted for the TRP1 promoter and coding region that enhances the efficiency of the polymerase chain reaction-disruption method. Yeast 13, 353-356.
3. Chook, Y. M. and Blobel, G. (2001). Karyopherins and nuclear import. Curr. Opin. Struct. Biol. 11, 703-715.
4. Ehrenhofer-Murray, A. E., Rivier, D. H. and Rine, J. (1997). The role of Sas2, an acetyltransferase homolog of Saccharomyces cerevisiae, in silencing and ORC function. Genetics 145, 923-934.
5. Enenkel, C., Blobel, G. and Rexach, M. (1995). Identification of a yeast karyopherin heterodimer that targets import substrate to mammalian nuclear pore complexes. J. Biol. Chem. 270, 16499-16502.
6. Falquet, L., Pagni, M., Bucher, P., Hulo, N., Sigrist, C. J., Hofmann, K. and Bairoch, A. (2002). The PROSITE database, its status in 2002. Nucleic Acids Res. 30, 235-238.
7. Franke, J., Reimann, B., Hartmann, E., Kohlerl, M. and Wiedmann, B. (2001). Evidence for a nuclear passage of nascent polypeptide-associated complex subunits in yeast. J. Cell Sci. 114, 2641-2648.
8. Fromont-Racine, M., Rain, J.-C. and Legrain, P. (1997). Toward a functional analysis of the yeast genome through exhaustive two-hybrid screens. Nat. Genet. 16, 277-282.
9. Giaever, G., Chu, A. M., Ni, L., Connelly, C., Riles, L., Veronneau, S., Dow,S., Lucau-Danila, A., Anderson, K., Andre, B. et al. (2002). Functional profiling of the Saccharomyces cerevisiae genome. Nature 418, 387-391.
10. Gölich, D., Vogel, F., Mills, A. D., Hartmann, E. and Laskey, R. A. (1995). Distinct functions for the two importin subunits in nuclear protein import. Nature 377, 246-248.
11. Jäkel, S. and Görlich, D. (1998). Importin, transportin, RanBP5 and RanBP7 mediate nuclear import of ribosomal proteins in mammalian cells. EMBO J. 17, 4491-4502.
12. Jäkel, S., Albig, W., Kutay, U., Bischoff, F. R., Schwamborn, K., Doenecke, D. and Gölich, D. (1999). The importinβ/importin 7 heterodimer is a functional nuclear import receptor for histone H1. EMBO J. 18, 2411-2423.
13. Kalderon, D., Roberts, B. L., Richardson, W. D. and Smith, A. E. (1984). A short aniino acid sequence able to specify nuclear location. Cell 39, 499-509.
14. Kobor, M. S., Venkatasubrahmanyam, S., Meneghini, M. D., Gin, J. W., Jennings, J. L., Link, A. J., Madhani, H. D. and Rine, J. (2004). A protein complex containing the conserved Swi2/Snf2-related ATPase Swr1p deposits histone variant H2A.Z into euchromatin. PLoS Biol. 2, e131.
15. Kuersten, S., Ohno, M. and Mattaj, I. W. (2001). Nucleocytoplasmic transport: Ran, beta and beyond. Trends Cell Biol. 11, 497-503.
16. Letunic, I., Copley, R. P-, Schmidt, S., Ciecarelli, F. D., Doerks, T., Schultz,J., Ponting, C. P. and Bork, P. (2004). SMART 4.0: towards genomic data integration. Nucleic Acids Res. 32, D142-D144.
17. Meijsing, S. H. and Ehrenhofer-Murray, A. E. (2001). The silencing complex SAS-I links histone acetylation to the assembly of repressed chromatin by CAF-I and Asf1 in Saccharomyces cerevisiae. Genes Dev. 15, 3169-3182.
18. Mosammaparast, N., Jackson, K. R., Guo, Y., Brame, C. J., Shabanowitz,J., Hunt, D. F. and Pemberton, L. F. (2001). Nuclear import of histones H2A and H2B is mediated by a network of karyopherins. J. Cell Biol. 153, 251-262.
19. Mosammaparast, N., Guo, Y., Shabanowitz, J., Hunt, D. F. and Pemberton, L. F. (2002a). Pathways mediating the nuclear import of histones H3 and H4 in yeast. J. Biol. Chem. 277, 862-868.
20. Mosammaparast, N., Ewart, C.S. and Pemberton, L. F. (2002b). A role for nucleosome assembly protein I in the nuclear transport of histones H2A and H2B. EMBO J. 21, 6527-6538.
21. Niedenthal, R. K., Riles, L., Johnston, M. and Hegemann, J. H. (1996). Green fluorescent protein as a marker for gene expression and subcellular localization in budding yeast. Yeast 12, 773-786.
22. Osada, S., Sutton, A., Muster, N., Brown, C. E., Yates, J. R., III, Sternglanz, R. and Workman, J. L. (2001). The yeast SAS (something about silencing) protein complex contains a MYST-type putative acetyltransferase and functions with chromatin assembly factor ASF1. Genes Dev. 15, 3155-3168.
23. Pemberton, L. F., Blobel, G. and Rosenblum, J. S. (1998). Transport routes through the nuclear pore complex. Curr. Opin. Cell Biol. 10, 392-399.
24. Reifsnyder, C., Lowell, J., Clarke, A. and Pillus, L. (1996). Yeast silencing genes and human genes associated with AML and HIV-1 Tat interactions are homologous with acetyltransferases. Nat. Genetics 14, 42-49.
25. Rigaut, G., Shevchenko, A., Rutz, B., Wilm, M., Mann, M. and Séraphin, B. (1999). A generic protein purification method for protein complex characterization and proteome exploration. Nat. Biotech. 17, 1030-1032.
26. Robbins, J., Dilworth, S. M., Laskey, R. A. and Dingwall, C. (1991). Two interdependent basic domains in nucleoplasmin nuclear targeting sequence: identification of a class of bipartite nuclear targeting sequence. Cell 64, 615-623.
27. Rout, M. P. and Aitchison, J. D. (2001). The nuclear pore complex as a transport machine. J. Biol. Chem. 276, 16593-16596.
28. Rout, M. P., Blobel, G. and Aitchison, J. D. (1997). A distinct nuclear import pathway used by ribosomal proteins. Cell 89, 715-725.
29. Rout, M. P., Aitchison, J. D., Suprapto, A., Hjertaas, K., Zhao, Y. and Chait, B. T. (2000). The yeast nuclear pore complex: composition, architecture and transport mechanism. J Cell Biol. 148, 635-651.
30. Rusche, L. N., Kirchmaier, A. L. and Rine, J. (2003). The establishment, inheritance, and function of silenced chromatin in Saccharomyces cerevisiae. Annu. Rev. Biochem. 72, 481-516.
31. Schaper, S., Fromont-Racine, M., Linder, P., de la Cruz, J., Namane, A., and Yaniv, M. (2001). A yeast homolog of chromatin assembly factor 1 is involved in early ribosome assembly. Curr. Biol. 11, 1885-1890.
32. Seedorf, M. and Silver P. A. (1997). Importin/karyopherin protein family members required for mRNA export from the nucleus. Proc. Natl. Acad. Sci. USA 94, 8590-8595.
33. Stage-Zimmermann, T., Schmidt, U. and Silver, P. A. (2000). Factors affecting nuclear export of the 60S ribosomal subunit in vivo. Mol Biol Cell 11, 3777-3789.
34. Strahl, B. D. and Allis, C. D. (2000). The language of covalent histone modifications. Nature 403, 41-45.
35. Sutton, A., Shia, W. J., Band, D., Kaufman, P. D., Osada, S., Workman, J. L. and Sternglanz, R. (2003). Sas4 and Sas5 are required for the histone acetyltransferase activity of Sas2 in the SAS complex. J. Biol. Chem. 273, 16887-16892.
36. Titov, A. A. and Blobel, G. (1999). The karyopherin Kap122p/Pdr6p imports both subunits of the transcription factor IIA into the nucleus. J. Cell Biol. 147, 235-246,
37. Xu, E. Y., Kim, S. and Rivier, D. (1999). SAS4 and SAS5 are locus-specific regulators of silencing in Saccharomyces cerevisiae. Genetics 153, 25-33.
38. Yong, J., Wan, L. and Dreyfuss, G. (2004). Why do cells need an assembly machine for RNA-protein complexes? Trends Cell Biol. 14, 226-232.