-
1
-
-
17744375048
-
Polycystic kidney disease
-
In: Avner ED, Harmon WE, Niaudet P, Williams & Wilkins, Philadelphia
-
Dell KM, Avner ED 2003 Polycystic kidney disease. In: Avner ED, Harmon WE, Niaudet P (eds) Pediatric Nephrology. Lippincott, Williams & Wilkins, Philadelphia, pp 675-699.
-
(2003)
Pediatric Nephrology. Lippincott
, pp. 675-699
-
-
Dell, K.M.1
Avner, E.D.2
-
2
-
-
0034799491
-
A novel inhibitor of tumor necrosis factor-alpha converting enzyme ameliorates polycystic kidney disease
-
Dell KM, Nemo R, Sweeney WE Jr, Levin JI, Frost P, Avner ED 2001 A novel inhibitor of tumor necrosis factor-alpha converting enzyme ameliorates polycystic kidney disease. Kidney Int 60:1240-1248.
-
(2001)
Kidney Int
, vol.60
, pp. 1240-1248
-
-
Dell, K.M.1
Nemo, R.2
Sweeney, W.E.3
Levin, J.I.4
Frost, P.5
Avner, E.D.6
-
3
-
-
0031986343
-
Expression of transforming growth factor alpha and epidermal growth factor receptor in adult polycystic kidney disease
-
Lee DC, Chan KW, Chan SY 1998 Expression of transforming growth factor alpha and epidermal growth factor receptor in adult polycystic kidney disease. J Urol 159:291-296.
-
(1998)
J Urol
, vol.159
, pp. 291-296
-
-
Lee, D.C.1
Chan, K.W.2
Chan, S.Y.3
-
4
-
-
0026537284
-
Expression of differentiation antigens and growth-related genes in normal kidney, autosomal dominant polycystic kidney disease, and renal cell carcinoma
-
Klingel R, Dippold W, Storkel S, Meyerzum Buschenfelde KH, Kohler H 1992 Expression of differentiation antigens and growth-related genes in normal kidney, autosomal dominant polycystic kidney disease, and renal cell carcinoma. Am J Kidney Dis 19:22-30.
-
(1992)
Am J Kidney Dis
, vol.19
, pp. 22-30
-
-
Klingel, R.1
Dippold, W.2
Storkel, S.3
Meyerzum Buschenfelde, K.H.4
Kohler, H.5
-
5
-
-
0028501443
-
Renal cysts in transgenic mice expressing transforming growth factor-alpha
-
Lowden DA, Lindemann GW, Merlino G, Barash BD, Calvet JP, Gattone VH II 1994 Renal cysts in transgenic mice expressing transforming growth factor-alpha. J Lab Clin Med 124:386-394.
-
(1994)
J Lab Clin Med
, vol.124
, pp. 386-394
-
-
Lowden, D.A.1
Lindemann, G.W.2
Merlino, G.3
Barash, B.D.4
Calvet, J.P.5
Gattone, V.H.6
-
6
-
-
0030075246
-
Renal expression of a transforming growth factor-alpha transgene accelerates the progression of inherited, slowly progressive polycystic kidney disease in the mouse
-
Gattone VH II, Kuenstler KA, Lindemann GW, Lu X, Cowley BD Jr, Rankin CA, Calvet JP 1996 Renal expression of a transforming growth factor-alpha transgene accelerates the progression of inherited, slowly progressive polycystic kidney disease in the mouse. J Lab Clin Med 127:214-222.
-
(1996)
J Lab Clin Med
, vol.127
, pp. 214-222
-
-
Gattone, V.H.1
Kuenstler, K.A.2
Lindemann, G.W.3
Lu, X.4
Cowley, B.D.5
Rankin, C.A.6
Calvet, J.P.7
-
7
-
-
0033995015
-
Treatment of polycystic kidney disease with a novel tyrosine kinase inhibitor
-
Sweeney WE, Chen Y, Nakanishi K, Frost P, Avner ED 2000 Treatment of polycystic kidney disease with a novel tyrosine kinase inhibitor. Kidney Int 57:33-40.
-
(2000)
Kidney Int
, vol.57
, pp. 33-40
-
-
Sweeney, W.E.1
Chen, Y.2
Nakanishi, K.3
Frost, P.4
Avner, E.D.5
-
8
-
-
0142249413
-
EGF receptor tyrosine kinase inhibition attenuates the development of PKD in Han:SPRD rats
-
Torres VE, Sweeney WE Jr, Wang X, Qian Q, Harris PC, Frost P, Avner ED 2003 EGF receptor tyrosine kinase inhibition attenuates the development of PKD in Han:SPRD rats. Kidney Int 64:1573-1579.
-
(2003)
Kidney Int
, vol.64
, pp. 1573-1579
-
-
Torres, V.E.1
Sweeney, W.E.2
Wang, X.3
Qian, Q.4
Harris, P.C.5
Frost, P.6
Avner, E.D.7
-
9
-
-
0141451943
-
Combination treatment of PKD utilizing dual inhibition of EGF-receptor activity and ligand bioavailability
-
Sweeney WE Jr, Hamahira K, Sweeney J, Garcia-Gatrell M, Frost P, Avner ED 2003 Combination treatment of PKD utilizing dual inhibition of EGF-receptor activity and ligand bioavailability. Kidney Int 64:1310-1319.
-
(2003)
Kidney Int
, vol.64
, pp. 1310-1319
-
-
Sweeney, W.E.1
Hamahira, K.2
Sweeney, J.3
Garcia-Gatrell, M.4
Frost, P.5
Avner, E.D.6
-
10
-
-
0037385521
-
Positional cloning of jcpk/bpk locus of the mouse
-
Cogswell C, Price SJ, Hou X, Guay-Woodford LM, Flaherty L, Bryda EC 2003 Positional cloning of jcpk/bpk locus of the mouse. Mamm Genome 14:242-249.
-
(2003)
Mamm Genome
, vol.14
, pp. 242-249
-
-
Cogswell, C.1
Price, S.J.2
Hou, X.3
Guay-Woodford, L.M.4
Flaherty, L.5
Bryda, E.C.6
-
11
-
-
0027315183
-
Mice with a null mutation of the TGF alpha gene have abnormal skin architecture, wavy hair, and curly whiskers and often develop corneal inflammation
-
Mann GB, Fowler KJ, Gabriel A, Nice EC, Williams RL, Dunn AR 1993 Mice with a null mutation of the TGF alpha gene have abnormal skin architecture, wavy hair, and curly whiskers and often develop corneal inflammation. Cell 73:249-261.
-
(1993)
Cell
, vol.73
, pp. 249-261
-
-
Mann, G.B.1
Fowler, K.J.2
Gabriel, A.3
Nice, E.C.4
Williams, R.L.5
Dunn, A.R.6
-
12
-
-
0027297643
-
TGF-α deficiency results in hair follicle and eye abnormalities in targeted and waved-1 mice
-
Luetteke NC, Qiu TH, Peiffer RL, Oliver P, Smithies O, Lee DC 1993 TGF-α deficiency results in hair follicle and eye abnormalities in targeted and waved-1 mice. Cell 73:263-278.
-
(1993)
Cell
, vol.73
, pp. 263-278
-
-
Luetteke, N.C.1
Qiu, T.H.2
Peiffer, R.L.3
Oliver, P.4
Smithies, O.5
Lee, D.C.6
-
13
-
-
0027406817
-
Renal and biliary abnormalities in a new murine model of autosomal recessive polycystic kidney disease
-
Nauta J, Ozawa Y, Sweeney WE Jr, Rutledge JC, Avner ED 1993 Renal and biliary abnormalities in a new murine model of autosomal recessive polycystic kidney disease. Pediatr Nephrol 7:163-172.
-
(1993)
Pediatr Nephrol
, vol.7
, pp. 163-172
-
-
Nauta, J.1
Ozawa, Y.2
Sweeney, W.E.3
Rutledge, J.C.4
Avner, E.D.5
-
14
-
-
0034121514
-
Proximal tubular cysts in fetal human autosomal recessive polycystic kidney disease
-
Nakanishi K, Sweeney WE Jr, Zerres K, Guay-Woodford LM, Avner ED 2000 Proximal tubular cysts in fetal human autosomal recessive polycystic kidney disease. J Am Soc Nephrol 11:760-763.
-
(2000)
J am Soc Nephrol
, vol.11
, pp. 760-763
-
-
Nakanishi, K.1
Sweeney, W.E.2
Zerres, K.3
Guay-Woodford, L.M.4
Avner, E.D.5
-
15
-
-
2442683969
-
EGF-related growth factors in the pathogenesis of murine ARPKD
-
MacRae Dell K, Nemo R, Sweeney WE Jr, Avner ED 2004 EGF-related growth factors in the pathogenesis of murine ARPKD. Kidney Int 65:2018-2029.
-
(2004)
Kidney Int
, vol.65
, pp. 2018-2029
-
-
Macrae Dell, K.1
Nemo, R.2
Sweeney, W.E.3
Avner, E.D.4
-
16
-
-
0027715057
-
Hereditary error in epidermal growth factor prohormone metabolism in a rat model of autosomal dominant polycystic kidney disease
-
Lakshmanan J, Eysselein V 1993 Hereditary error in epidermal growth factor prohormone metabolism in a rat model of autosomal dominant polycystic kidney disease. Biochem Biophys Res Commun 197:1083-1093.
-
(1993)
Biochem Biophys Res Commun
, vol.197
, pp. 1083-1093
-
-
Lakshmanan, J.1
Eysselein, V.2
-
17
-
-
0027370022
-
An inborn error in epidermal growth factor prohormone metabolism in a mouse model of autosomal recessive polycystic kidney disease
-
Lakshmanan J, Fisher DA 1993 An inborn error in epidermal growth factor prohormone metabolism in a mouse model of autosomal recessive polycystic kidney disease. Biochem Biophys Res Commun 196:892-901.
-
(1993)
Biochem Biophys Res Commun
, vol.196
, pp. 892-901
-
-
Lakshmanan, J.1
Fisher, D.A.2
-
18
-
-
0028797993
-
Epidermal growth factor precursor is present in a variety of human renal cyst fluids
-
Moskowitz DW, Bonar SL, Liu W, Sirgi CF, Marcus MD, Clayman RV 1995 Epidermal growth factor precursor is present in a variety of human renal cyst fluids. J Urol 153:578-583.
-
(1995)
J Urol
, vol.153
, pp. 578-583
-
-
Moskowitz, D.W.1
Bonar, S.L.2
Liu, W.3
Sirgi, C.F.4
Marcus, M.D.5
Clayman, R.V.6
-
19
-
-
0027999935
-
Epidermal growth factor and endothelin in cyst fluid from autosomal dominant polycystic kidney disease cases: Possible evidence of heterogeneity in cystogenesis
-
Munemura C, Uemasu J, Kawasaki H 1994 Epidermal growth factor and endothelin in cyst fluid from autosomal dominant polycystic kidney disease cases: possible evidence of heterogeneity in cystogenesis. Am J Kidney Dis 24:561-568.
-
(1994)
Am J Kidney Dis
, vol.24
, pp. 561-568
-
-
Munemura, C.1
Uemasu, J.2
Kawasaki, H.3
-
20
-
-
0025240839
-
Defective epidermal growth factor gene expression in mice with polycystic kidney disease
-
Gattone VH Jr, Andrews GK, Niu FW, Chadwick LJ, Klein RM, Calvet JP 1990 Defective epidermal growth factor gene expression in mice with polycystic kidney disease. Dev Biol 138:225-230.
-
(1990)
Dev Biol
, vol.138
, pp. 225-230
-
-
Gattone, V.H.1
Rews, G.K.2
Niu, F.W.3
Chadwick, L.J.4
Klein, R.M.5
Calvet, J.P.6
-
21
-
-
0028909692
-
Epidermal growth factor receptor expression is abnormal in murine polycystic kidney
-
Orellana SA, Sweeney WE, Neff CD, Avner ED 1995 Epidermal growth factor receptor expression is abnormal in murine polycystic kidney. Kidney Int 47:490-499.
-
(1995)
Kidney Int
, vol.47
, pp. 490-499
-
-
Orellana, S.A.1
Sweeney, W.E.2
Neff, C.D.3
Avner, E.D.4
-
22
-
-
0030444935
-
The cytosolic 47-kilodalton protein that binds to the 3′ untranslated region of epidermal growth factor transcripts responds to orchiectomy in a tissue-specific fashion
-
Sheflin LG, Brooks EM, Keegan BP, Spaulding SW 1996 The cytosolic 47-kilodalton protein that binds to the 3′ untranslated region of epidermal growth factor transcripts responds to orchiectomy in a tissue-specific fashion. Endocrinology 137:5616-5623.
-
(1996)
Endocrinology
, vol.137
, pp. 5616-5623
-
-
Sheflin, L.G.1
Brooks, E.M.2
Keegan, B.P.3
Spaulding, S.W.4
-
23
-
-
0024316391
-
Recombinant human epidermal growth factor precursor is a glycosylated membrane protein with biological activity
-
Mroczkowski B, Reich M, Chen K, Bell GI, Cohen S 1989 Recombinant human epidermal growth factor precursor is a glycosylated membrane protein with biological activity. Mol Cell Biol 9:2771-2778.
-
(1989)
Mol Cell Biol
, vol.9
, pp. 2771-2778
-
-
Mroczkowski, B.1
Reich, M.2
Chen, K.3
Bell, G.I.4
Cohen, S.5
-
24
-
-
0032795261
-
Targeted inactivation of the EGF and amphiregulin genes reveals distinct roles for EGF receptor ligands in mouse mammary gland development
-
Luetteke NC, Qui TH, Fenton SE, Troyer KL, Riedel RF, Chang A, Lee DC 1999 Targeted inactivation of the EGF and amphiregulin genes reveals distinct roles for EGF receptor ligands in mouse mammary gland development. Development 126:2739-2750.
-
(1999)
Development
, vol.126
, pp. 2739-2750
-
-
Luetteke, N.C.1
Qui, T.H.2
Fenton, S.E.3
Troyer, K.L.4
Riedel, R.F.5
Chang, A.6
Lee, D.C.7
-
25
-
-
0037382091
-
Overexpression of heparin-binding EGF-like growth factor in mouse pancreas results in fibrosis and epithelial metaplasia
-
Means AL, Ray KC, Singh AB, Washington MK, Whitehead RH, Harris RC Jr, Wright CV, Coffey RJ Jr, Leach SD 2003 Overexpression of heparin-binding EGF-like growth factor in mouse pancreas results in fibrosis and epithelial metaplasia. Gastroenterology 124:1020-1036.
-
(2003)
Gastroenterology
, vol.124
, pp. 1020-1036
-
-
Means, A.L.1
Ray, K.C.2
Singh, A.B.3
Washington, M.K.4
Whitehead, R.H.5
Harris, R.C.6
Wright, C.V.7
Coffey, R.J.8
Leach, S.D.9
-
26
-
-
0036079914
-
Transgenic overexpression of amphiregulin induces a mitogenic response selectively in pancreatic duct cells
-
Wagner M, Weber CK, Bressau F, Greten FR, Stagge V, Ebert M, Leach SD, Adler G, Schmid RM 2002 Transgenic overexpression of amphiregulin induces a mitogenic response selectively in pancreatic duct cells. Gastroenterology 122:1898-1912.
-
(2002)
Gastroenterology
, vol.122
, pp. 1898-1912
-
-
Wagner, M.1
Weber, C.K.2
Bressau, F.3
Greten, F.R.4
Stagge, V.5
Ebert, M.6
Leach, S.D.7
Adler, G.8
Schmid, R.M.9
-
27
-
-
0034690033
-
Mammary gland specific hEGF receptor transgene expression induces neoplasia and inhibits differentiation
-
Brandt R, Eisenbrandt R, Leenders F, Zschiesche W, Binas B, Juergensen C, Theuring F 2000 Mammary gland specific hEGF receptor transgene expression induces neoplasia and inhibits differentiation. Oncogene 19:2129-2137.
-
(2000)
Oncogene
, vol.19
, pp. 2129-2137
-
-
Brandt, R.1
Eisenbrandt, R.2
Leenders, F.3
Zschiesche, W.4
Binas, B.5
Juergensen, C.6
Theuring, F.7
-
28
-
-
0034674581
-
Overexpression of epidermal growth factor induced hypospermatogenesis in transgenic mice
-
Wong RW, Kwan RW, Mak PH, Mak KK, Sham MH, Chan SY 2000 Overexpression of epidermal growth factor induced hypospermatogenesis in transgenic mice. J Biol Chem 275:18297-18301.
-
(2000)
J Biol Chem
, vol.275
, pp. 18297-18301
-
-
Wong, R.W.1
Kwan, R.W.2
Mak, P.H.3
Mak, K.K.4
Sham, M.H.5
Chan, S.Y.6
-
29
-
-
0033127103
-
Transforming growth factor-alpha deficiency reduces pulmonary fibrosis in transgenic mice
-
Madtes DK, Elston AL, Hackman RC, Dunn AR, Clark JG 1999 Transforming growth factor-alpha deficiency reduces pulmonary fibrosis in transgenic mice. Am J Respir Cell Mol Biol 20:924-934.
-
(1999)
Am J Respir Cell Mol Biol
, vol.20
, pp. 924-934
-
-
Madtes, D.K.1
Elston, A.L.2
Hackman, R.C.3
Dunn, A.R.4
Clark, J.G.5
-
30
-
-
0030838652
-
Temporal expression of trefoil peptides in the TGF-alpha knockout mouse after gastric ulceration
-
Cook GA, Yeomans ND, Giraud AS 1997 Temporal expression of trefoil peptides in the TGF-alpha knockout mouse after gastric ulceration. Am J Physiol 272:G1540-G1549.
-
(1997)
Am J Physiol
, vol.272
-
-
Cook, G.A.1
Yeomans, N.D.2
Giraud, A.S.3
-
31
-
-
0035214648
-
Lack of effects of transforming growth factor-alpha gene knockout on peripheral nerve regeneration may result from compensatory mechanisms
-
Xian CJ, Li L, Deng YS, Zhao SP, Zhou XF 2001 Lack of effects of transforming growth factor-alpha gene knockout on peripheral nerve regeneration may result from compensatory mechanisms. Exp Neurol 172:182-188.
-
(2001)
Exp Neurol
, vol.172
, pp. 182-188
-
-
Xian, C.J.1
Li, L.2
Deng, Y.S.3
Zhao, S.P.4
Zhou, X.F.5
-
32
-
-
0042093746
-
Mutations in a novel gene, NPHP3, cause adolescent nephronophthisis, tapato-retinal degeneration and hepatic fibrosis
-
Olbrich H, Fliegauf M, Hoefele J, Kispert A, Otto E, Volz A, Wolf MT, Sasmaz G, Trauer U, Reinhardt R, Sudbrak R, Antignac C, Gretz N, Walz G, Schermer B, Benzing T, Hildebrandt F, Omran H 2003 Mutations in a novel gene, NPHP3, cause adolescent nephronophthisis, tapato-retinal degeneration and hepatic fibrosis. Nat Genet 34:455-459.
-
(2003)
Nat Genet
, vol.34
, pp. 455-459
-
-
Olbrich, H.1
Fliegauf, M.2
Hoefele, J.3
Kispert, A.4
Otto, E.5
Volz, A.6
Wolf, M.T.7
Sasmaz, G.8
Trauer, U.9
Reinhardt, R.10
Sudbrak, R.11
Antignac, C.12
Gretz, N.13
Walz, G.14
Schermer, B.15
Benzing, T.16
Hildebrandt, F.17
Omran, H.18
-
33
-
-
0035137357
-
Renal dysfunction but not cystic change is ameliorated by neonatal epidermal growth factor in bpk mice
-
Nakanishi K, Gattone VH II, Sweeney WE, Avner ED 2001 Renal dysfunction but not cystic change is ameliorated by neonatal epidermal growth factor in bpk mice. Pediatr Nephrol 16:45-50.
-
(2001)
Pediatr Nephrol
, vol.16
, pp. 45-50
-
-
Nakanishi, K.1
Gattone, V.2
Sweeney, W.E.3
Avner, E.D.4
-
34
-
-
0032515018
-
An essential role for ectodomain shedding in mammalian development
-
Peschon JJ, Slack JL, Reddy P, Stocking KL, Sunnarborg SW, Lee DC, Russell WE, Castner BJ, Johnson RS, Fitzner JN, Boyce RW, Nelson N, Kozlosky CJ, Wolfson MF, Rauch CT, Cerretti DP, Paxton RJ, March CJ, Black RA 1998 An essential role for ectodomain shedding in mammalian development. Science 282:1281-1284.
-
(1998)
Science
, vol.282
, pp. 1281-1284
-
-
Peschon, J.J.1
Slack, J.L.2
Reddy, P.3
Stocking, K.L.4
Sunnarborg, S.W.5
Lee, D.C.6
Russell, W.E.7
Castner, B.J.8
Johnson, R.S.9
Fitzner, J.N.10
Boyce, R.W.11
Nelson, N.12
Kozlosky, C.J.13
Wolfson, M.F.14
Rauch, C.T.15
Cerretti, D.P.16
Paxton, R.J.17
March, C.J.18
Black, R.A.19
-
36
-
-
0026520472
-
The physiology of transforming growth factor-α
-
Derynck R 1992 The physiology of transforming growth factor-α. Adv Cancer Res 58:27-52.
-
(1992)
Adv Cancer Res
, vol.58
, pp. 27-52
-
-
Derynck, R.1
-
37
-
-
0038581051
-
TACE cleavage of proamphiregulin regulates GPCR-induced proliferation and motility of cancer cells
-
Gschwind A, Hart S, Fischer OM, Ullrich A 2003 TACE cleavage of proamphiregulin regulates GPCR-induced proliferation and motility of cancer cells. EMBO J 22:2411-2421.
-
(2003)
EMBO J
, vol.22
, pp. 2411-2421
-
-
Gschwind, A.1
Hart, S.2
Fischer, O.M.3
Ullrich, A.4
-
38
-
-
2642541715
-
Selective roles for tumor necrosis factor alpha-converting enzyme/ADAM17 in the shedding of the epidermal growth factor receptor ligand family: The juxtamembrane stalk determines cleavage efficiency
-
Hinkle CL, Sunnarborg SW, Loiselle D, Parker CE, Stevenson M, Russell WE, Lee DC 2004 Selective roles for tumor necrosis factor alpha-converting enzyme/ADAM17 in the shedding of the epidermal growth factor receptor ligand family: the juxtamembrane stalk determines cleavage efficiency. J Biol Chem 279:24179-24188.
-
(2004)
J Biol Chem
, vol.279
, pp. 24179-24188
-
-
Hinkle, C.L.1
Sunnarborg, S.W.2
Loiselle, D.3
Parker, C.E.4
Stevenson, M.5
Russell, W.E.6
Lee, D.C.7
-
39
-
-
0034616385
-
Tumor necrosis factor-alpha-converting enzyme is required for cleavage of erbB4/HER4
-
Rio C, Buxbaum JD, Peschon JJ, Corfas G 2000 Tumor necrosis factor-alpha-converting enzyme is required for cleavage of erbB4/HER4. J Biol Chem 275:10379-10387.
-
(2000)
J Biol Chem
, vol.275
, pp. 10379-10387
-
-
Rio, C.1
Buxbaum, J.D.2
Peschon, J.J.3
Corfas, G.4
-
40
-
-
0029744471
-
Matrix metalloproteinases and TIMPS in cultured C57BL/6J-cpk kidney tubules
-
Rankin CA, Suzuki K, Itoh Y, Ziemer DM, Grantham JJ, Calvet JP, Nagase H 1996 Matrix metalloproteinases and TIMPS in cultured C57BL/6J-cpk kidney tubules. Kidney Int 50:835-844.
-
(1996)
Kidney Int
, vol.50
, pp. 835-844
-
-
Rankin, C.A.1
Suzuki, K.2
Itoh, Y.3
Ziemer, D.M.4
Grantham, J.J.5
Calvet, J.P.6
Nagase, H.7
-
41
-
-
0035203705
-
Phenotypic analysis of conditionally immortalized cells isolated from the BPK model of ARPKD
-
Sweeney WE Jr, Kusner L, Carlin CR, Chang S, Futey L, Cotton CU, Dell KM, Avner ED 2001 Phenotypic analysis of conditionally immortalized cells isolated from the BPK model of ARPKD. Am J Physiol Cell Physiol 281:C1695-C1705.
-
(2001)
Am J Physiol Cell Physiol
, vol.281
-
-
Sweeney, W.E.1
Kusner, L.2
Carlin, C.R.3
Chang, S.4
Futey, L.5
Cotton, C.U.6
Dell, K.M.7
Avner, E.D.8
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