A novel inhibitor of tumor necrosis factor-α converting enzyme ameliorates polycystic kidney disease

Kidney International

Volumn 60, Issue 4, 2001, Pages 1240-1248

  MacRae Dell, Katherine ^a,b   Nemo, Raghad ^a,b   Sweeney, William E ^a,b   Levin, Jeremy I ^a,b   Frost, Philip ^a,b   Avner, Ellis D ^a,b  

^a CASE WESTERN RESERVE UNIVERSITY   (United States)

^b PFIZER INC   (United States)

Author keywords

Autosomal recessive PKD; Collecting tubule cysts; Epidermal growth factor receptor ligand; Proximal tubule cysts; Transforming growth factor

Indexed keywords

CREATININE; ENZYME INHIBITOR; EPIDERMAL GROWTH FACTOR RECEPTOR; LIGAND; MEMBRANE ENZYME; METALLOPROTEINASE; METALLOPROTEINASE INHIBITOR; NITROGEN; TUMOR NECROSIS FACTOR ALPHA CONVERTING ENZYME; UREA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BODY WEIGHT; CONCENTRATION RESPONSE; CONTROLLED STUDY; CREATININE BLOOD LEVEL; DISEASE COURSE; DOSE RESPONSE; DRUG EFFECT; ENZYME DEGRADATION; ENZYME INHIBITION; ENZYME RELEASE; IMMUNOHISTOCHEMISTRY; KIDNEY COLLECTING TUBULE; KIDNEY FUNCTION; KIDNEY MASS; KIDNEY POLYCYSTIC DISEASE; KIDNEY PROXIMAL TUBULE; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN SECRETION; TREATMENT OUTCOME; UREA NITROGEN BLOOD LEVEL;

EID: 0034799491     PISSN: 00852538     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1523-1755.2001.00963.x     Document Type: Article

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