Temporal expression of trefoil peptides in the TGF-α knockout mouse after gastric ulceration

American Journal of Physiology - Gastrointestinal and Liver Physiology

Volumn 272, Issue 6 35-6, 1997, Pages

  Cook, G A ^a   Yeomans, N D ^a   Giraud, A S ^a  

^a UNIVERSITY OF MELBOURNE   (Australia)

Author keywords

Gastric mucosal injury; Intestinal trefoil factor; Spasmolytic polypeptide; Transforming growth factor

Indexed keywords

TRANSFORMING GROWTH FACTOR ALPHA;

AMINO ACID SEQUENCE; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL DAMAGE; CELL MIGRATION; CELL MOTILITY; CELL PROLIFERATION; CONTROLLED STUDY; GENE EXPRESSION REGULATION; LAMINA PROPRIA; LIGAND BINDING; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; STOMACH ULCER; ULCER HEALING;

EID: 0030838652     PISSN: 01931857     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpgi.1997.272.6.g1540     Document Type: Article

References (47)

1. Alison, M. R., R. Chinery, R. Poulsom, P. Ashwood, J. M. Longcroft, and N. A. Wright. Experimental ulceration leads to sequential expression of spasmolytic polypeptide, intestinal trefoil factor, epidermal growth factor and transforming growth factor-α mRNAs in rat stomach. J. Pathol. 175: 405-414, 1995.
2. Babyatsky, M. W., M. De Beaumont, L. Thim, and D. K. Podolsky. Oral trefoil peptides protect against ethanol and indomethacin induced gastric injury in rats. Gastroenterology 110: 489-497, 1996.
3. Barnard, J. A., R. D. Beauchamp, W. E. Russell, R. N. Dubois, and R. J. Coffey. Epidermal growth factor-related peptides and their relevance to gastrointestinal pathophysiology. Gastroenterology 108: 564-580, 1995.
4. Barrandon, Y., and H. Green. Cell migration is essential for sustained growth of keratinocyte colonies: the roles of transforming growth factor-α and epidermal growth factor. Cell 50: 1131-1137, 1987.
5. Chinery, R., and R. J. Playford. Combined intestinal trefoil factor and epidemal growth factor is prophylactic against indomethacin induced gastric damage in the rat. Clin. Sci. (Lond.) 88: 401-403, 1995.
6. Chinery, R., R. Poulsom, L. A. Rogers, R. E. Jeffrey, J. M. Longcroft, A. M. Hanby, and N. A. Wright. Localization of intestinal-trefoil factor mRNA in rat stomach and intestine by hybridisation in situ. Biochem. J. 285: 5-8, 1992.
7. Cohen, S. Isolation of a mouse submaxillary gland protein accelerating incisor eruption and eyelid opening of new-born animals. J. Biol. Chem. 237: 1155-1162, 1962.
8. De Larco, J. E., and G. J. Todaro. Growth factors from murine sarcoma virus-transformed cells. Proc. Natl. Acad. Sci. USA 75: 4001-4005, 1978.
9. Derynck, R. Transforming growth factor-α: structure and biological activities. J. Cell. Biochem. 32: 293-304, 1986.
10. Dignass, A., K. Lynch-Devaney, H. Kindon, L. Thim, and D. K. Podolsky. Trefoil peptides promote epithelial migration through a transforming growth factor beta-independent pathway. J. Clin. Invest. 94: 376-383, 1994.
11. Hanby, A. M., R. Poulsom, S. Singh, G. Elia, R. E. Jeffrey, and N. A. Wright. Spasmolytic polypeptide is a major antral peptide: distribution of the trefoil peptides human spasmolytic polypeptide and pS2 in the stomach. Gastroenterology 105: 1110-1116, 1993.
12. Henry, J. A., M. K. Bennett, N. H. Piggott, D. L. Levett, F. E. May, and B. R. Westley. Expression of the pNR-2/pS2 protein in diverse human epithelial tumours. Br. J. Cancer 64: 677-682, 1991.
13. Hoosein, N. M., L. Thim, K. H. Jorgensen, and M. G. Brattain. Growth stimulatory effect of pancreatic spasmolytic polypeptide on cultured colon and breast tumor cells. FEBS Lett. 247: 303-306, 1989.
14. Jeffrey, G. P., P. S. Oates, T. C. Wang, M. W. Babyatsky, and S. J. Brand. Spasmolytic polypeptide: a trefoil peptide secreted by rat gastric mucous cells. Gastroenterology 106: 336-345, 1994.
15. Jorgensen, K. D., B. Diamant, K. H. Jorgensen, and L. Thim. Pancreatic spamolytic polypeptide (PSP). III. Pharmacology of a new porcine pancreatic polypeptide with spasmolytic and gastric acid secretion inhibitory effects. Regul. Pept. 3: 231-243, 1982.
16. Jorgensen, K. H., L. Thim, and H. E. Jacobsen. Pancreatic spasmolytic polypeptide (PSP). I. Preparation and initial chemical characterization of a new polypeptide from porcine pancreas. Regul. Pept. 3: 207-219, 1982.
17. Karam, S. M. Dynamics of epithelial cells in the corpus of the mouse stomach. IV. Bidirectional migration of parietal cells ending in their gradual degeneration and loss. Anat. Rec. 236: 314-332, 1993.
18. Karam, S. M., and C. P. Leblond. Dynamics of epithelial cells in the corpus of the mouse stomach. III. Inward migration of neck cells followed by progressive transformation into zymogenic cells. Anat. Rec. 236: 297-313, 1993.
19. Karam, S. M., and C. P. Leblond. Dynamics of epithelial cells in the corpus of.the mouse stomach. V. Behaviour of enteroendocrine and caveolated cells: general conclusions on cell kinetics in the oxyntic epithelium. Anat. Rec. 236: 333-340, 1993.
20. Kelley, S. M., and J. O. Hunter. Epidermal growth factor stimulates synthesis and secretion of mucus glycoproteins in human gastric mucosa. Clin. Sci. (Lond.) 79: 425-427, 1990.
21. Kindon, H., C. Pothoulakis, L. Thim, K. Lynch-Devaney, and D. K. Podolsky. Trefoil peptide protection of intestinal epithelial barrier function: cooperative interaction with mucin glycoprotein. Gastroenterology 109: 516-523, 1995.
22. Konturek, S. J., M. Cieszkowski, J. Jaworek, T. Brzozowski, and H. Gregory. Effects of epidermal growth factor on gastrointestinal secretions. Am. J. Physiol. 246 (Gastrointest. Liver Physiol. 9): G580-G586, 1984.
23. Mann, G. B., K. J. Fowler, A. Gabriel, E. C. Nice, R. L. Williams, and A. R. Dunn. Mice with a null mutation of the TGF-α gene have abnormal skin architecture, wavy hair, and curly whiskers and often develop corneal inflammation. Cell 73: 249-261, 1993.
24. Martin, P., J. Hopkinson-Woolley, and J. McCluskey. Growth factors and cutaneous wound repair. Prog. Growth Factor Res. 4: 25-44, 1992.
25. Mashimo, H., D. K. Podolsky, and M. C. Fishman. Structure and expression of murine intestinal trefoil factor: high evolutionary conservation and postnatal expression. Biochem. Biophys. Res. Comm. 210: 31-37, 1995.
26. Masiakowski, P., R., Breathnach, J. Bloch, F. Gannon, A. Krust, and P. Chambon. Cloning of cDNA sequences of hormone regulated genes from the MCF-7 human breast cancer cell line. Nucleic Acids Res. 10: 7895-7903, 1982.
27. Playford, R. J., T. Marchbank, R. Chinery, R. Evison, M. Pignatelli, R. A. Boulton, L. Thim, and A. M. Hanby. Human spasmolytic polypeptide is a cytoprotective agent that stimulates cell migration. Gastroenterology 108: 108-116, 1995.
28. Podolsky, D. K., K. Lynch-Devaney, J. L. Stow, P. Oates, B. Murgue, M. De Beaumont, B. E. Sands, and Y. R. Mahida. Identification of human intestinal trefoil factor. Goblet cell-specific expression of a peptide targeted for apical secretion. J. Biol. Chem. 268: 6694-6702, 1993.
29. Polk, W. H., Jr., P. J. Dempsey, W. E. Russell, P. I. Brown, R. D. Beauchamp, J. A. Barnard, and R. J. Coffey. Increased production of transforming growth factor α following acute gastric injury. Gastroenterology 102: 1467-1474, 1992.
30. Poulsom, R., R. Chinery, C. Sarraf, E.-N. Lalani, G. Stamp, G. Elia, and N. A. Wright. Trefoil peptide expression in intestinal adaptation and renewal. Scand. J. Gastroenterol. 27: 17-28, 1992.
31. Poulsom, R., and N. A. Wright. Trefoil peptides: a newly recognized family of epithelial mucin-associated molecules. Am. J. Physiol 265 (Gastrointest. Liver Physiol. 28): G205-G213, 1993.
32. Rhodes, J. A., J. P. Tam, U. Finke, M. Sanders, J. Bernanke, W. Silen, and R. A. Murphy. Transforming growth factor α inhibits secretion of gastric acid. Proc. Natl. Acad. Sci. USA 83: 3844-3846, 1986.
33. Rio, M. C., J. P. Ballocq, J.Y. Daniel, C. Tomasetto, R. Lathe, M. P. Chenard, A. Batzenschlager, and P. Chambon. Breast cancer-associated pS2 protein: synthesis and secretion by normal stomach mucosa. Science 241: 705-708, 1988.
34. Rio, M. C., M. P. Chenard, C. Wolf, L. Marcellin, C. Tomasetto, R. Lathe, J. P. Bellocq, and P. Chambon. Induction of pS2 and hSP genes as markers of mucosal ulceration of the digestive tract. Gastroenterology 100: 375-379, 1991.
35. Romano, M., W. H. Polk, J. A. Awad, C. L. Arteaga, L. B. Nanney, M. J. Wargovich, R. Krause, C. R. Boland, and R. J. Coffey. Transforming growth factor-α protection against drug-induced injury to the rat gastric mucosa in vivo. J. Clin. Invest. 90: 2409-2421, 1992.
36. Suemori, S., K. Lynch-Devaney, and D. K. Podolsky. Identification and characterization of rat intestinal factor: tissue- and cell-specific member of the trefoil protein family. Proc. Natl. Acad. Sci. USA 88: 11017-11021, 1991.
37. Tarnawski, A., D. Hollander, J. Stachura, W. J. Krause, M. Eltorai, W. Dabros, and H. Gergely. Vascular and microvascular changes - key factors in the development of acetic acid-induced ulcers in rats. J. Clin. Gastroenterol. 12: S148-S157, 1990.
38. Tarnawski, A., J. Stachura, T. Durbin, and H. Gergely. Expression of epidermal growth factor receptor in the rat gastric oxyntic mucosa. J. Clin. Gastroenterol. 13, Suppl. 1: S109-S113, 1991.
39. Tarnawski, A., J. Stachura, T. Durbin, I. J. Sarfeh, and H. Gergely. Increased expression of epidermal growth factor receptor during gastric ulcer healing in rats. Gastroenterology 102: 695-698, 1992.
40. Taupin, D. R., G. A. Cook, N. D. Yeomans, and A. S. Giraud. Increased trefoil peptide expression occurs late in the healing phase in a model of gastric ulceration in the rat (Abstract). Gastroenterology 106: A195, 1994.
41. Taupin, D. R., A. Shulkes, and A. S. Giraud. Developmental expression of trefoil peptides in the rat gastrointestinal tract (Abstract). Gastroenterology 108: A756, 1995.
42. Thim, L. A new family of growth factor-like peptides. FEBS Lett. 250: 85-90, 1989.
43. Thomas, D. M., M. M. Nasim, W. J. Gullik, and M. R. Alison. Immuno-reactivity of transforming growth factor-α in the normal adult gastrointestinal tract. Gut 33: 628-631, 1992.
44. Tomita, M., H. Itoh, N. Ishikawa, A. Higa, H. Ide, Y. Murakoma, H. Maruyama, Y. Koga, and Y. Nawa. Molecular cloning of mouse intestinal trefoil factor and its expression during goblet cell changes. Biochem. J. 311: 293-297, 1995.
45. Wright, N. A., C. Pike, and G. Elia. Induction of a novel epidermal growth factor-secreting cell lineage by mucosal ulceration in gastrointestinal stem cells. Nature 343: 82-85, 1990.
46. Wright, N. A., R. Poulsom, G. W. H. Stamp, P. A. Hall, R. E. Jeffrey, J. M. Longcroft, M. C. Rio, C. Tomasetto, and P. Chambon. Epidermal growth factor (EGF/URO) induces expression of regulatory peptides in damaged human gastrointestinal tissues. J. Pathol. 162: 279-284, 1990.
47. Wright, N. A., R. Poulsom, G. Stamp, S. Van Noorden, C. Sarraf, G. Elia, D. Ahnen, R. Jeffrey, J. Longcroft, C. Pike, M.-C. Rio, and P. Chambon. Trefoil peptide gene expression in gastrointestinal epithelial cells in inflammatory bowel disease. Gastroenterology 104: 12-20, 1993.