CXCR6 within T-helper (Th) and T-cytotoxic (Tc) type 1 lymphocytes in Graves' disease (GD)

European Journal of Endocrinology

Volumn 152, Issue 4, 2005, Pages 635-643

  Aust, G ^a   Kamprad, M ^a   Lamesch, P ^a   Schmucking E ^a  

^a UNIVERSITY OF LEIPZIG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ANTITHYROID AGENT; CD4 ANTIGEN; CD8 ANTIGEN; CHEMOKINE RECEPTOR; CHEMOKINE RECEPTOR CXCR6; COMPLEMENTARY DNA; GAMMA INTERFERON; GRANZYME A; MESSENGER RNA; THYROID PEROXIDASE ANTIBODY; UNCLASSIFIED DRUG;

ADULT; ANTIBODY BLOOD LEVEL; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOTOXIC T LYMPHOCYTE; EFFECTOR CELL; FEMALE; FIBROBLAST; FLOW CYTOMETRY; GRAVES DISEASE; HASHIMOTO DISEASE; HELPER CELL; HUMAN; HUMAN CELL; HUMAN TISSUE; LYMPHOCYTE MIGRATION; MALE; NATURAL KILLER CELL; PATHOGENESIS; PERIPHERAL LYMPHOCYTE; PRIORITY JOURNAL; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; T LYMPHOCYTE SUBPOPULATION; TH1 CELL; THYROID CELL; THYROID GLAND; THYROID NODULE;

ADOLESCENT; ADULT; DNA, COMPLEMENTARY; FEMALE; FLOW CYTOMETRY; GRAVES DISEASE; HUMANS; KILLER CELLS, NATURAL; MALE; MIDDLE AGED; POLYMERASE CHAIN REACTION; RECEPTORS, CHEMOKINE; RECEPTORS, CYTOKINE; RECEPTORS, G-PROTEIN-COUPLED; RECEPTORS, VIRUS; RNA, MESSENGER; T-LYMPHOCYTES; T-LYMPHOCYTES, CYTOTOXIC; TH1 CELLS; THYROID GLAND;

EID: 17744376406     PISSN: 08044643     EISSN: None     Source Type: Journal    
DOI: 10.1530/eje.1.01892     Document Type: Article

References (44)

1. Mosmann TR, Li L & Sad S. Functions of CD8 T-cell subsets secreting different cytokine patterns. Seminars in Immunology 1997 9 87-92.
2. Rotondi M, Lazzeri E, Romagnani P & Serio M. Role for interferon-gamma inducible chemokines in endocrine autoimmunity: an expanding field. Journal of Endocrinological Investigation 2003 26 177-180.
3. Dogan RN, Vasu C, Holterman MJ & Prabhakar BS. Absence of IL-4, and not suppression of the Th2 response, prevents development of experimental autoimmune Graves' disease. Journal of Immunology 2003 170 2195-2204.
4. Nagayama Y, Mizuguchi H, Hayakawa T, Niwa M, McLachlan SM & Rapoport B. Prevention of autoantibody-mediated Graves'-like hyperthyroidism in mice with IL-4, a Th2 cytokine. Journal of Immunology 2003 170 3522-3527.
5. Nagayama Y, McLachlan SM, Rapoport B & Oishi K. Graves' hyperthyroidism and the hygiene hypothesis in a mouse model. Endocrinology 2004 145 5075-5079.
6. Nagayama Y, Watanabe K, Niwa M, McLachlan SM & Rapoport B. Schistosoma mansoni and alpha-galactosylceramide: prophylactic effect of Th1 Immune suppression in a mouse model of Graves' hyperthyroidism. Journal of Immunology 2004 173 2167-2173.
7. Nagayama Y, Saitoh O, McLachlan SM, Rapoport B, Kano H & Kumazawa Y. TSH receptor-adenovirus-induced Graves' hyperthyroidism is attenuated in both interferon-gamma and interleukin-4 knockout mice; implications for the Th1/Th2 paradigm. Clinical and Experimental Immunology 2004 138 417-422.
8. Sallusto F, Lenig D, Mackay CR & Lanzavecchia A. Flexible programs of chemokine receptor expression on human polarized T helper 1 and 2 lymphocytes. Journal of Experimental Medicine 1998 187 875-883.
9. Annunziato F, Cosmi L, Galli G, Beltrame C, Romagnani P, Manetti R, Romagnani S & Maggi E. Assessment of chemokine receptor expression by human Th1 and Th2 cells in vitro and in vivo. Journal of Leukocyte Biology 1999 65 691-699.
10. Unutmaz D, Xiang W, Sunshine MJ, Campbell J, Butcher E & Littman DR. The primate lentiviral receptor Bonzo/STRL33 is coordinately regulated with CCR5 and its expression pattern is conserved between human and mouse. Journal of Immunology 2000 165 3284-3292.
11. Deng HK, Unutmaz D, KewalRamani VN & Littman DR. Expression cloning of new receptors used by simian and human immunodeficiency viruses. Nature 1997 388 296-300.
12. Liao F, Alkhatib G, Peden KW, Sharma G, Berger EA & Farber JM. STRL33, A novel chemokine receptor-like protein, functions as a fusion cofactor for both macrophage-tropic and T cell line-tropic HIV-1. Journal of Experimental Medicine 1997 185 2015-2023.
13. Wilbanks A, Zondlo SC, Murphy K, Mak S, Soler D, Langdon P, Andrew DP, Wu L & Briskin M. Expression cloning of the STRL33/BONZO/TYMSTRligand reveals elements of CC, CXC, and CX3C chemokines. Journal of Immunology 2001 166 5145-5154.
14. Shimaoka T, Kume N, Minami M, Hayashida K, Kataoka H, Kita T & Yonehara S. Molecular cloning of a novel scavenger receptor for oxidized low density lipoprotein, SR-PSOX, on macrophages. Journal of Biological Chemistry 2000 275 40663-40666.
15. Matloubian M, David A, Engel S, Ryan JE & Cyster JG. A transmembrane CXC chemokine is a ligand for HIV-coreceptor Bonzo. Nature Immunology 2000 1 298-304.
16. Shimaoka T, Nakayama T, Fukumoto N, Kume N, Takahashi S, Yamaguchi J, Minami M, Hayashida K, Kita T, Ohsumi J et al. Cell surface-anchored SR-PSOX/CXC chemokine ligand 16 mediates firm adhesion of CXC chemokine receptor 6-expressing cells. Journal of Leukocyte Biology 2004 75 267-274.
17. Abel S, Hundhausen C, Mentlein R, Schulte A, Berkhout TA, Broadway N, Hartmann D, Sedlacek R, Dietrich S, Muetze B et al. The transmembrane CXC-chemokine ligand 16 is induced by IFN-gamma and TNF-alpha and shed by the activity of the dis-integrin-like metalloproteinase ADAM10. Journal of Immunology 2004 172 6362-6372.
18. Wang J, Holmes TH, Cheung R, Greenberg HB & He XS. Expression of chemokine receptors on intrahepatic and peripheral lymphocytes in chronic hepatitis C infection: its relationship to liver inflammation. Journal of Infectious Diseases 2004 190 989-997.
19. Chandrasekar B, Bysani S & Mummidi S. CXCL16 Signals via Gi, Phosphatidylinositol 3-Kinase, Akt, IκB Kinase, and Nuclear Factor-κB and Induces Cell-Cell Adhesion and Aortic Smooth Muscle Cell Proliferation. Journal of Biological Chemistry 2004 279 3188-3196.
20. Kim CH, Kunkel EJ, Boisvert J, Johnston B, Campbell JJ, Genovese MC, Greenberg HB & Butcher EC. Bonzo/CXCR6 expression defines type 1-polarized T-cell subsets with extralymphoid tissue homing potential. Journal of Clinical Investigation 2001 107 595-601.
21. Aust G, Sittig D, Becherer L, Anderegg U, Schütz A, Lamesch P & Schmücking E. The role of CXCR5 and its ligand CXCL13 in the compartimentalization of lymphocytes in thyroids affected by Graves' disease. European Journal of Endocrinology 2004 150 225-234.
22. Hamann J, Eichler W, Vogel B, Stortelers C, Hamann D, Horejsi V & van Lier RA. CD97 workshop panel report. In Leucocyte Typing VI. White Cell Differentiation Antigens, pp 527-529. Eds T Kishimoto, H Kikutani & AEGKr von dem Borne et al. New York: Garland Publishing, 1997.
23. Aust G, Heuer M, Laue S, Lehmann I, Hofmann A, Heldin N-E & Scherbaum WA. Expression of TNF-alpha mRNA and protein in pathological thyroid tissue and carcinoma cell lines. Clinical and Experimental Immunology 1996 105 148-154.
24. Koprak S, Matheravidathu S, Springer M, Gould S & Dumont FJ. Down-regulation of cell surface CXCR6 expression during T cell activation is predominantly mediated by calcineurin. Cell Immunology 2003 223 1-12.
25. Aust G, Steinert M, Kiessling S, Kamprad M & Simchen C. Reduced expression of Stromal-derived factor 1 in autonomous thyroid adenomas and its regulation in thyroid-derived cells. Journal of Clinical Endocrinology and Metabolism 2001 86 3368-3376.
26. Köhler T, Schill C, Deininger MW, Krahl R, Borchert S, Hasenclever D, Leiblein S, Wagner O & Niederwieser D. High Bad and Bax mRNA expression correlate with negative outcome in acute myeloid leukemia (AML). Leukemia 2002 16 22-29.
27. Köhler T, Rost AK & Remke H. Calibration and storage of DNA competitors used for contamination-protected competitive PCR. Biotechniques 1997 23 722-726.
28. Aust G, Steinert M, Boltze C, Kiessling S & Simchen C. GRO-alpha in normal and pathological thyroid tissues and its regulation in thyroid-derived cells. Journal of Endocrinology 2001 170 513-520.
29. Aust G, Sittig D, Steinert M, Lamesch P & Lohmann T. Graves' disease is associated with an altered CXCR3 and CCR5 expression in thyroid-derived compared with peripheral blood lymphocytes. Clinical and Experimental Immunology 2002 127 479-485.
30. Qin S, Rottman JB, Myers P, Kassam N, Weinblatt M, Loetscher M, Koch AE, Moser B & Mackay CR. The chemokine receptors CXCR3 and CCR5 mark subsets of T cells associated with certain inflammatory reactions. Journal of Clinical Investigation 1998 101 746-754.
31. Bonecchi R, Bianchi G, Bordignon PP, D'Ambrosio D, Lang R, Borsatti A, Sozzani S, Allavena P, Gray PA, Mantovani A & Sinigaglia F. Differential expression of chemokine receptors and chemotactic responsiveness of type 1 T helper cells (Th1s) and Th2s. Journal of Experimental Medicine 1998 187 129-134.
32. Kahn J, Ingraham RH, Shirley F, Migaki GI & Kishimoto TK. Membrane proximal cleavage of L-selectin: identification of the cleavage site and a 6-kD transmembrane peptide fragment of L-selectin. Journal of Cell Biology 1994 125 461-470.
33. Armengol MP, Juan M, Lucas-Martin A, Fernandez-Figueras MT, Jaraquemada D, Gallart T & Pujol-Borrell R. Thyroid autoimmune disease: demonstration of thyroid antigen-specific B cells and recombination-activating gene expression in chemokine-containing active intrathyroidal germinal centers. American Journal of Pathology 2001 159 861-873.
34. Stassi G & De Maria R. Autoimmune thyroid disease: new models of cell death in autoimmunity. Nature Reviews Immunology 2002 2 195-204.
35. Kemp EH, Metcalfe RA, Smith KA, Woodroofe MN, Watson PF & Weetman AP. Detection and localization of chemokine gene expression in autoimmune thyroid disease. Clinical Endocrinology 2003 59 207-213.
36. Garcia-Lopez MA, Sancho D, Sanchez-Madrid F & Marazuela M. Thyrocytes from autoimmune thyroid disorders produce the chemokines IP-10 and Mig and attract CXCR3 + lymphocytes. Journal of Clinical Endocrinology and Metabolism 2001 86 5008-5016.
37. Romagnani P, Rotondi M, Lazzeri E, Lasagni L, Francalanci M, Buonamano A, Milani S, Vitti P, Chiovato L, Tonacchera M, Bellastella A & Serio M. Expression of IP-10/CXCL10 and MIG/CXCL9 in the thyroid and increased levels of IP-10/CXCL10 in the serum of patients with recent-onset Graves' disease. American Journal of Pathology 2002 161 195-206.
38. Paschke R, Vogg M, Swillens S & Usadel KH. Correlation of microsomal antibodies with the intensity of the intrathyroidal autoimmune process in Graves' disease. Journal of Clinical Endocrinology and Metabolism 1993 77 939-943.
39. Weetman AP, McGregor AM, Wheeler MH & Hall R. Extrathyroidal sites of autoantibody synthesis in Graves' disease. Clinical and Experimental Immunology 1984 56 330-336.
40. McLachlan SM, Fawcett J, Atherton MC, Thompson P, Baylis P & Smith BR. Thyroid autoantibody synthesis by cultures of thyroid and peripheral blood lymphocytes. II. Effect of thyroglobulin on thyroglobulin antibody synthesis. Clinical and Experimental Immunology 1983 52 620-628.
41. Voorby HA, Kabel PJ, de Haan M, Jeucken PH, van der Gaag RD, de Baets MH & Drexhage HA. Dendritic cells and class II MHC expression on thyrocytes during the autoimmune thyroid disease of the BB rat. Clinical Immunology and Immunopathology 1990 55 9-22.
42. Minami M, Kume N, Shimaoka T, Kataoka H, Hayashida K, Akiyama Y, Nagata I, Ando K, Nobuyoshi M, Hanyuu M et al. Expression of SR-PSOX, a novel cell-surface scavenger receptor for phosphatidylserine and oxidized LDL in human atherosclerotic lesions. Arteriosclerosis Thrombosis and Vascular Biology 2001 21 1796-1800.
43. Aust G & Scherbaum WA. Expression of cytokines in the thyroid: thyrocytes as potential cytokine producers. Experimental and Clinical Endocrinology & Diabetes 1996 104 64-67.
44. Kasai K, Banba N, Motohashi S, Hattori Y, Manaka K & Shimoda SI. Expression of monocyte chemoattractant protein-1 mRNA and protein in cultured human thyrocytes. FEBS Letters 1996 394 137-140.