CXCL16 Signals via Gi, Phosphatidylinositol 3-Kinase, Akt, IκB Kinase, and Nuclear Factor-κB and Induces Cell-Cell Adhesion and Aortic Smooth Muscle Cell Proliferation

Journal of Biological Chemistry

Volumn 279, Issue 5, 2004, Pages 3188-3196

  Chandrasekar, Bysani ^a,b   Bysani, Sailaja ^a   Mummidi, Srinivas ^a  

^a Mays Cancer Center at UT Health San Antonio   (United States)

^b UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIODEGRADATION; DISEASES; DNA; ENZYME KINETICS; GENES; MUSCLE; PROTEINS;

CELLULAR PROLIFERATION;

BIOCHEMISTRY;

ALPHA CHEMOKINE; CELL ADHESION MOLECULE; CHEMOKINE; CXCL16 CHEMOKINE; CXCL16 PROTEIN, HUMAN; DACTINOMYCIN; ENZYME INHIBITOR; I KAPPA B KINASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INHIBITORY GUANINE NUCLEOTIDE BINDING PROTEIN; LOW DENSITY LIPOPROTEIN; MEMBRANE PROTEIN; NUCLEIC ACID SYNTHESIS INHIBITOR; ONCOPROTEIN; PERTUSSIS TOXIN; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; PROTEIN SERINE THREONINE KINASE; PROTO ONCOGENE PROTEIN AKT; PROTO-ONCOGENE PROTEIN AKT; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

AORTA; AORTA MEDIA; ARTERIOSCLEROSIS; ARTICLE; ATHEROSCLEROSIS; CELL ADHESION; CELL CULTURE; CELL DEATH; CELL DIVISION; CELL PROLIFERATION; CELL SEPARATION; CYTOLOGY; DISEASE COURSE; DNA BINDING; DOSE RESPONSE; ENZYME ACTIVATION; FLOW CYTOMETRY; FOAM CELL; HUMAN; HUMAN CELL; MACROPHAGE; MACROPHAGE ACTIVATION; METABOLISM; NUCLEOTIDE SEQUENCE; PATHOLOGY; PHOSPHORYLATION; PLASMA CELL; PRIORITY JOURNAL; RECEPTOR UPREGULATION; SIGNAL TRANSDUCTION; SMOOTH MUSCLE FIBER; TIME; VASCULAR DISEASE;

1-PHOSPHATIDYLINOSITOL 3-KINASE; AORTA; ARTERIOSCLEROSIS; CELL ADHESION; CELL DEATH; CELL DIVISION; CELL SEPARATION; CELLS, CULTURED; CHEMOKINES, CXC; DACTINOMYCIN; DISEASE PROGRESSION; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME ACTIVATION; ENZYME INHIBITORS; FLOW CYTOMETRY; GTP-BINDING PROTEIN ALPHA SUBUNITS, GI-GO; HUMANS; I-KAPPA B KINASE; MACROPHAGES; MEMBRANE PROTEINS; MYOCYTES, SMOOTH MUSCLE; NF-KAPPA B; NUCLEIC ACID SYNTHESIS INHIBITORS; PERTUSSIS TOXIN; PHOSPHORYLATION; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-AKT; RECEPTORS, IMMUNOLOGIC; RECEPTORS, SCAVENGER; SIGNAL TRANSDUCTION; TIME FACTORS;

EID: 0942276399     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M311660200     Document Type: Article

References (29)

1. Wilbanks, A., Zondlo, S. C., Murphy, K., Mak, S., Soler, D., Langdon, P., Andrew, D. P., Wu, L., and Briskin, M. (2001) J. Immunol. 166, 5145-5154
2. Matloubian, M., David, A., Engel, S., Ryan, J. E., and Cyster, J. G. (2000) Nat. Immunol. 1, 298-304
3. Bazan, J. F., Bacon, K. B., Hardiman, G., Wang, W., Soo, K., Rossi, D., Greaves, D. R., Zlotnik, A., and Schall, T. J. (1997) Nature 385, 640-644
4. Shashkin, P., Simpson, D., Mishin, V., Chesnutt, B., and Ley, K. (2003) Arterioscler. Thromb. Vasc. Biol. 23, 148-149
5. Heydtmann, M., and Adams, D. H. (2002) Gut 50, 150-152
6. Unutmaz, D., Xiang, W., Sunshine, M. J., Campbell, J., Butcher, E., and Littman, D. R. (2000) J. Immunol. 165, 3284-3292
7. Kim, C. H., Kunkel, E. J., Boisvert, J., Johnston, B., Campbell, J. J., Genovese, M. C., Greenberg, H. B., and Butcher, E. C. (2001) J. Clin. Invest. 107, 595-601
8. Kim, C. H., Johnston, B., and Butcher, E. C. (2002) Blood 100, 11-16
9. Nakayama, T., Hieshima, K., Izawa, D., Tatsumi, Y., Kanamaru, A., and Yoshie, O. (2003) J. Immunol. 170, 1136-1140
10. Shimaoka, T., Nakayama, T., Kume, N., Takahashi, S., Yamaguchi, J., Minami, M., Hayashida, K., Kita, T., Ohsumi, J., Yoshie, O., and Yonehara, S. (2003) J. Immunol. 171, 1647-1651
11. Shimaoka, T., Kume, N., Minami, M., Hayashida, K., Kataoka, H., Kita, T., and Yonehara, S. (2000) J. Biol. Chem. 275, 40663-40666
12. Minami, M., Kume, N., Shimaoka, T., Kataoka, H., Hayashida, K., Akiyama, Y., Nagata, I., Ando, K., Nobuyoshi, M., Hanyuu, M., Komeda, M., Yonehara, S., and Kita, T. (2001) Arterioscler. Thromb. Vasc. Biol. 21, 1796-1800
13. Hofnagel, O., Luechtenborg, B., Plenz, G., and Robenek, H. (2002) Arterioscler. Thromb. Vasc. Biol. 22, 710-711
14. Chandrasekar, B., Mummidi, S., Perla, R. P., Bysani, S., Dulin, N. O., Liu, F., and Melby, P. C. (2003) Biochem. J. 373, 547-558
15. Chandrasekar, B., Melby, P. C., Sarau, H. M., Raveendran, M., Perla, R. P., Marelli-Berg, F. M., Dulin, N. O., and Singh, I. S. (2003) J. Biol. Chem. 278, 4675-4686
16. Gschwind, A., Hart, S., Fischer, O. M., and Ullrich, A. (2003) EMBO J. 22, 2411-2421
17. Troyer, D. A., Chandrasekar, B., Barnes, J. L., and Fernandes, G. (1997) Clin. Exp. Immunol. 108, 58-62
18. Datta, S. R., Brunet, A., and Greenberg, M. E. (1999) Genes Dev. 13, 2905-2927
19. Mercurio, F., Zhu, H., Murray, B. W., Shevchenko, A., Bennett, B. L., Li, J., Young, D. B., Barbosa, M., Mann, M., Manning, A., and Rao, A. (1997) Science 278, 860-866
20. Black, R. A. (2002) Int. J. Biochem. Cell Biol. 34, 1-5
21. Han, Y., He, T., Huang, D. R., Pardo, C. A., and Ransohoff, R. M. (2001) J. Clin. Invest. 108, 425-435
22. Kane, L. P., Shapiro, V. S., Stokoe, D., and Weiss, A. (1999) Curr. Biol. 9, 601-604
23. Romashkova, J. A., and Makarov, S. S. (1999) Nature 401, 86-90
24. Tsou, C. L., Haskell, C. A., and Charo, I. F. (2001) J. Biol. Chem. 276, 44622-44626
25. Garton, K. J., Gough, P. J., Blobel, C. P., Murphy, G., Greaves, D. R., Dempsey, P. J., and Raines, E. W. (2001) J. Biol. Chem. 276, 37993-38001
26. Brunet, A., Bonni, A., Zigmond, M. J., Lin, M. Z., Juo, P., Hu, L. S., Anderson, M. J., Arden, K. C., Blenis, J., and Greenberg, M. E. (1999) Cell 96, 857-868
27. Onuffer, J. J., and Horuk, R. (2002) Trends Pharmacol. Sci. 23, 459-467
28. Rossi, D., and Zlotnik, A. (2000) Annu. Rev. Immunol. 18, 217-242
29. Terkeltaub, R., Boisvert, W. A., and Curtiss, L. K. (1998) Curr. Opin. Lipidol. 9, 397-405