Thioredoxin System in Premature and Newborn Biology

Antioxidants and Redox Signaling

Volumn 6, Issue 1, 2004, Pages 177-184

  Das, Kumuda C ^a  

^a UNIVERSITY OF TEXAS HEALTH CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIOXIDANT; GLUTATHIONE; PEROXIREDOXIN; THIOREDOXIN; THIOREDOXIN REDUCTASE;

CELL PROLIFERATION; EMBRYO DEVELOPMENT; HUMAN; HYPEROXIA; NEWBORN DISEASE; OXIDATION REDUCTION REACTION; PATHOGENESIS; PREMATURITY; PRIORITY JOURNAL; REVIEW; SIGNAL TRANSDUCTION;

EID: 0346340021     PISSN: 15230864     EISSN: None     Source Type: Journal    
DOI: 10.1089/152308604771978480     Document Type: Review

References (83)

1. Abman SH, Chatfield BA, Hall SL, and McMurtry IF. Role of endothelium-derived relaxing factor during transition of pulmonary circulation at birth. Am J Physiol 259: H1921-H1927, 1990.
2. Arner ES and Holmgren A. Physiological functions of thioredoxin and thioredoxin reductase. Eur J Biochem 267: 6102-6109, 2000.
3. Bing YZ, Hirao Y, Takenouchi N, Che LM, Nakamura H, Yodoi J, and Nagai T. Effects of thioredoxin on the preimplantation development of bovine embryos. Theriogenology 59: 863-873, 2003.
4. Bjornstedt M, Xue J, Huang W, Akesson B, and Holmgren A. The thioredoxin and glutaredoxin systems are efficient electron donors to human plasma glutathione peroxidase. J Biol Chem 269: 29382-29384, 1994.
5. Bjornstedt M, Hamberg M, Kumar S, Xue J, and Holmgren A. Human thioredoxin reductase directly reduces lipid hydroperoxides by NADPH and selenocystine strongly stimulates the reaction via catalytically generated selenols. J Biol Chem 270: 11761-11764, 1995.
6. Black SM, Johengen MJ, Ma ZD, Bristow J, and Soifer SJ. Ventilation and oxygenation induce endothelial nitric oxide synthase gene expression in the lungs of fetal lambs. J Clin Invest 100: 1448-1458, 1997.
7. Buchanan BB, Schurmann P, Decottignies P, and Lozano RM. Thioredoxin: a multifunctional regulatory protein with a bright future in technology and medicine. Arch Biochem Biophys 314: 257-260, 1994.
8. Chae HZ, Chung SJ, and Rhee SG. Thioredoxin-dependent peroxide reductase from yeast. J Biol Chem 269: 27670-27678, 1994.
9. Chang WH, Reddy SP, Di YP, Yoneda K, Harper R, and Wu R. Regulation of thioredoxin gene expression by vitamin A in human airway epithelial cells. Am J Respir Cell Mol Biol 26: 627-635, 2002.
10. Clarke FM. Identification of molecules and mechanisms involved in the 'early pregnancy factor' system. Reprod Fertil Dev 4: 423-433, 1992.
11. Coalson JJ, Winter VT, Gerstmann DR, Idell S, King RJ, and Delemos RA. Pathophysiologic, morphometric, and biochemical studies of the premature baboon with bronchopulmonary dysplasia. Am Rev Respir Dis 145: 872-881, 1992.
12. Coalson JJ, Winter VT, Siler-Khodr T, and Yoder BA. Neonatal chronic lung disease in extremely immature baboons. Am J Respir Crit Care Med 160: 1333-1346, 1999.
13. Damdimopoulos AE, Miranda-Vizuete A, Pelto-Huikko M, Gustafsson JA, and Spyrou G. Human mitochondrial thioredoxin. Involvement in mitochondrial membrane potential and cell death. J Biol Chem 277: 33249-33257, 2002.
14. 2-terminal kinase-mediated redox-dependent degradation of IkappaB: role of thioredoxin in NF-kappaB activation. J Biol Chem 276: 4662-4670, 2001.
15. Das KC and Das CK. Thioredoxin, a singlet oxygen quencher and hydroxyl radical scavenger: redox independent functions. Biochem Biophys Res Commun 277: 443-447, 2000.
16. Das KC, Lewis-Molock Y, and White CW. Elevation of manganese superoxide dismutase gene expression by thioredoxin. Am J Respir Cell Mol Biol 17: 713-726, 1997.
17. Das KC, Guo XL, and White CW. Hyperoxia induces thioredoxin and thioredoxin reductase gene expression in lungs of premature baboons with respiratory distress and bronchopulmonary dysplasia. Chest 116 (1 Suppl): 101S, 1999.
18. Das KC, Guo XL, and White CW. Induction of thioredoxin and thioredoxin reductase gene expression in lungs of new-born primates by oxygen. Am J Physiol 276: L530-L539, 1999.
19. Das KC, Pahl PM, Guo XL, and White CW. Induction of peroxiredoxin gene expression by oxygen in lungs of new-born primates. Am J Respir Cell Mol Biol 25: 226-232, 2001.
20. Ejima K, Koji T, Nanri H, Kashimura M, and Ikeda M. Expression of thioredoxin and thioredoxin reductase in placentae of pregnant mice exposed to lipopolysaccharide. Placenta 20: 561-566, 1999.
21. Ejima K, Nanri H, Toki N, Kashimura M, and Ikeda M. Localization of thioredoxin reductase and thioredoxin in normal human placenta and their protective effect against oxidative stress. Placenta 20: 95-101, 1999.
22. Fernando MR, Nanri H, Yoshitake S, Nagata-Kuno K, and Minakami S. Thioredoxin regenerates proteins inactivated by oxidative stress in endothelial cells. Eur J Biochem 209: 917-922, 1992.
23. Fisher AB, Dodia C, Manevich Y, Chen JW, and Feinstein SI. Phospholipid hydroperoxides are substrates for non-selenium glutathione peroxidase. J Biol Chem 274: 21326-21334, 1999.
24. Frank L and Sosenko IR. Prenatal development of lung antioxidant enzymes in four species. J Pediatr 110: 106-110, 1987.
25. Gasdaska JR, Kirkpatrick DL, Montfort W, Kuperus M, Hill SR, Berggren M, and Powis G. Oxidative inactivation of thioredoxin as a cellular growth factor and protection by a Cys73→Ser mutation. Biochem Pharmacol 52: 1741-1747, 1996.
26. Goto Y, Noda Y, Narimoto K, Umaoka Y, and Mori T. Oxidative stress on mouse embryo development in vitro. Free Radic Biol Med 13: 47-53, 1992.
27. Goto Y, Noda Y, Mori T, and Nakano M. Increased generation of reactive oxygen species in embryos cultured in vitro. Free Radic Biol Med 15: 69-75, 1993.
28. Gratacos E. Lipid-mediated endothelial dysfunction: a common factor to preeclampsia and chronic vascular disease. Eur J Obstet Gynecol Reprod Biol 92: 63-66, 2000.
29. Gratacos E, Casals E, Deulofeu R, Gomez O, Cararach V, Alonso PL, and Fortuny A. Serum antibodies to oxidized low-density lipoprotein in pregnant women with preeclampsia and chronic hypertension: lack of correlation with lipid peroxides. Hypertens Pregnancy 20: 177-183, 2001.
30. Gratacos E, Casals E, Gomez O, Llurba E, Mercader I, Cararach V, and Cabero L. Increased susceptibility to low density lipoprotein oxidation in women with a history of pre-eclampsia. BJOG 110: 400-404, 2003.
31. Haddad JJ. Oxygen-sensing mechanisms and the regulation of redox-responsive transcription factors in development and pathophysiology. Respir Res 3: 26, 2002.
32. Haendeler J, Hoffmann J, Tischler V, Berk BC, Zeiher AM, and Dimmeler S. Redox regulatory and anti-apoptotic functions of thioredoxin depend on S-nitrosylation at cysteine 69. Nat Cell Biol 4: 743-749, 2002.
33. Hayashi T, Ueno Y, and Okamoto T. Oxidoreductive regulation of nuclear factor kappa B. Involvement of a cellular reducing catalyst thioredoxin. J Biol Chem 268: 11380-11388, 1993.
34. Hirota K, Murata M, Sachi Y, Nakamura H, Takeuchi J, Mori K, and Yodoi J. Distinct roles of thioredoxin in the cytoplasm and in the nucleus. A two-step mechanism of redox regulation of transcription factor NF-kappaB. J Biol Chem 274: 27891-27897, 1999.
35. Holmgren A. Thioredoxin. Annu Rev Biochem 54: 237-271, 1985.
36. Holmgren A. Antioxidant function of thioredoxin and glutaredoxin systems. Antioxid Redox Signal 2: 811-820, 2000.
37. Holmgren A. Redox regulation by thioredoxin and thioredoxin reductase. Biofactors 11: 63-64, 2000.
38. Huang LE, Arany Z, Livingston DM, and Bunn HF. Activation of hypoxia-inducible transcription factor depends primarily upon redox-sensitive stabilization of its alpha subunit. J Biol Chem 271: 32253-32259, 1996.
39. Joyce-Brady M, Oakes SM, Wuthrich D, and Laperche Y. Three alternative promoters of the rat gamma-glutamyl transferase gene are active in developing lung and are differentially regulated by oxygen after birth. J Clin Invest 97: 1774-1779, 1996.
40. Kang SW, Baines IC, and Rhee SG. Characterization of a mammalian peroxiredoxin that contains one conserved cysteine. J Biol Chem 273: 6303-6311, 1998.
41. 2 mixed-function oxidation system. J Biol Chem 263: 4704-4711, 1988.
42. Kobayashi M, Nakamura H, Yodoi J, and Shiota K. Immunohistochemical localization of thioredoxin and glutaredoxin in mouse embryos and fetuses. Antioxid Redox Signal 2: 653-663, 2000.
43. Kobayashi M, Nakamura H, Yodoi J, and Shiota K. Ontogenesis of anti-oxidative enzymes in mouse embryos and fetuses: an immunohistochemical study. Ital J Anat Embryol 106: 137-142, 2001.
44. Kobayashi-Miura M, Nakamura H, Yodoi J, and Shiota K. Thioredoxin, an anti-oxidant protein, protects mouse embryos from oxidative stress-induced developmental anomalies. Free Radic Res 36: 949-956, 2002.
45. Kraayenbrink AA, Dekker GA, van Kamp GJ, and van Geijn HP. Endothelial vasoactive mediators in preeclampsia. Am J Obstet Gynecol 169: 160-165, 1993.
46. Lee SR, Bar-Noy S, Kwon J, Levine RL, Stadtman TC, and Rhee SG. Mammalian thioredoxin reductase: oxidation of the C-terminal cysteine/selenocysteine active site forms a thioselenide, and replacement of selenium with sulfur markedly reduces catalytic activity. Proc Natl Acad Sci US A 97: 2521-2526, 2000.
47. Lim YS, Cha MK, Yun CH, Kim HK, Kim K, and Kim IH. Purification and characterization of thiol-specific antioxidant protein from human red blood cell: a new type of antioxidant protein. Biochem Biophys Res Commun 199: 199-206, 1994.
48. Lundstrom J and Holmgren A. Protein disulfide-isomerase is a substrate for thioredoxin reductase and has thioredoxin-like activity. J Biol Chem 265: 9114-9120, 1990.
49. Matsui M, Oshima M, Oshima H, Takaku K, Maruyama T, Yodoi J, and Taketo MM. Early embryonic lethality caused by targeted disruption of the mouse thioredoxin gene. Dev Biol 178: 179-185, 1996.
50. Matthews JR, Wakasugi N, Virelizier JL, Yodoi J, and Hay RT. Thioredoxin regulates the DNA binding activity of NF-kappa B by reduction of a disulphide bond involving cysteine 62. Nucleic Acids Res 20: 3821-3830, 1992.
51. McCarthy AL, Woolfson RG, Raju SK, and Poston L. Abnormal endothelial cell function of resistance arteries from women with preeclampsia. Am J Obstet Gynecol 168: 1323-1330, 1993.
52. Miranda-Vizuete A, Damdimopoulos AE, and Spyrou G. The mitochondrial thioredoxin system. Antioxid Redox Signal 2: 801-810, 2000.
53. Nakamura H, Matsuda M, Furuke K, Kitaoka Y, Iwata S, Toda K, Inamoto T, Yamaoka Y, Ozawa K, and Yodoi J. Adult T cell leukemia-derived factor/human thioredoxin protects endothelial F-2 cell injury caused by activated neutrophils or hydrogen peroxide. Immunol Lett 42: 75-80, 1994.
54. Nonn L, Williams RR, Erickson RP, and Powis G. The absence of mitochondrial thioredoxin 2 causes massive apoptosis, exencephaly, and early embryonic lethality in homozygous mice. Mol Cell Biol 23: 916-922, 2003.
55. Ohira A, Honda O, Gauntt CD, Yamamoto M, Hori K, Masutani H, Yodoi J, and Honda Y. Oxidative stress induces adult T cell leukemia derived factor/thioredoxin in the rat retina. Lab Invest 70: 279-285, 1994.
56. Okado-Matsumoto A, Matsumoto A, Fujii J, and Taniguchi N. Peroxiredoxin IV is a secretable protein with heparin-binding properties under reduced conditions. J Biochem (Tokyo) 127: 493-501, 2000.
57. Patel JM and Block ER. Sulfhydryl-disulfide modulation and the role of disulfide oxidoreductases in regulation of the catalytic activity of nitric oxide synthase in pulmonary artery endothelial cells. Am J Respir Cell Mol Biol 13: 352-359, 1995.
58. Patel JM, Zhang J, and Block ER. Nitric oxide-induced inhibition of lung endothelial cell nitric oxide synthase via interaction with allosteric thiols: role of thioredoxin in regulation of catalytic activity. Am J Respir Cell Mol Biol 15: 410-419, 1996.
59. Perkins AV, Di Trapani G, McKay MS, and Clarke FM. Immunocytochemical localization of thioredoxin in human trophoblast and decidua. Placenta 16: 635-642, 1995.
60. Powis G and Montfort WR. Properties and biological activities of thioredoxins. Annu Rev Biophys Biomol Struct 30: 421-455, 2001.
61. Powis G, Oblong JE, Gasdaska PY, Berggren M, Hill SR, and Kirkpatrick DL. The thioredoxin/thioredoxin reductase redox system and control of cell growth. Oncol Res 6: 539-544, 1994.
62. Powis G, Kirkpatrick DL, Angulo M, and Baker A. Thioredoxin redox control of cell growth and death and the effects of inhibitors. Chem Biol Interact 111-112: 23-34, 1998.
63. Powis G, Mustacich D, and Coon A. The role of the redox protein thioredoxin in cell growth and cancer. Free Radic Biol Med 29: 312-322, 2000.
64. Redman CW, Sacks GP, and Sargent IL. Preeclampsia: an excessive maternal inflammatory response to pregnancy. Am J Obstet Gynecol 180: 499-506, 1999.
65. Roberts JM and Hubel CA. Is oxidative stress the link in the two-stage model of preeclampsia? Lancet 354: 788-789, 1999.
66. Roberts JM, Taylor RN, Musci TJ, Rodgers GM, Hubel CA, and McLaughlin MK. Preeclampsia: an endothelial cell disorder. Am J Obstet Gynecol 161: 1200-1204, 1989.
67. Rubartelli A, Bajetto A, Allavena G, Wollman E, and Sitia R. Secretion of thioredoxin by normal and neoplastic cells through a leaderless secretory pathway. J Biol Chem 267: 24161-24164, 1992.
68. Sachi Y, Hirota K, Masutani H, Toda K, Okamoto T, Takigawa M, and Yodoi J. Induction of ADF/TRX by oxidative stress in keratinocytes and lymphoid cells. Immunol Lett 44: 189-193, 1995.
69. Sacks GP, Studena K, Sargent K, and Redman CW. Normal pregnancy and preeclampsia both produce inflammatory changes in peripheral blood leukocytes akin to those of sepsis. Am J Obstet Gynecol 179: 80-86, 1998.
70. Saitoh M, Nishitoh H, Fujii M, Takeda K, Tobiume K, Sawada Y, Kawabata M, Miyazono K, and Ichijo H. Mammalian thioredoxin is a direct inhibitor of apoptosis signal-regulating kinase (ASK) 1. EMBO J 17: 2596-2606, 1998.
71. Sandalova T, Zhong L, Lindqvist Y, Holmgren A, and Schneider G. Three-dimensional structure of a mammalian thioredoxin reductase: implications for mechanism and evolution of a selenocysteine-dependent enzyme. Proc Natl Acad Sci U S A 98: 9533-9538, 2001.
72. Singh AK and Shichi H. A novel glutathione peroxidase in bovine eye. Sequence analysis, mRNA level, and translation. J Biol Chem 273: 26171-26178, 1998.
73. Sosenko IR, Chen Y, Price LT, and Frank L. Failure of premature rabbits to increase lung antioxidant enzyme activities after hyperoxic exposure: antioxidant enzyme gene expression and pharmacologic intervention with endotoxin and dexamethasone. Pediatr Res 37: 469-475, 1995.
74. 2 upon thioredoxin-enriched lens epithelial cells. J Biol Chem 263: 4984-4990, 1988.
75. Stark JM. Inadequate reducing systems in pre-eclampsia: a complementary role for vitamins C and E with thioredoxin-related activities. BJOG 108: 339-343, 2001.
76. Sueoka K. [Comprehensive study on the expression mechanism of the early pregnancy associated substances and the implication for embryo development-structural determination of early pregnancy factor molecule and analysis of its homologous peptides]. Nippon Sanka Fujinka Gakkai Zasshi 44: 930-938, 1992.
77. Tanaka T, Nakamura H, Nishiyama A, Hosoi F, Masutani H, Wada H, and Yodoi J. Redox regulation by thioredoxin superfamily; protection against oxidative stress and aging. Free Radic Res 33: 851-855, 2000.
78. Tanaka T, Hosoi F, Yamaguchi-Iwai Y, Nakamura H, Masutani H, Ueda S, Nishiyama A, Takeda S, Wada H, Spyrou G, and Yodoi J. Thioredoxin-2 (TRX-2) is an essential gene regulating mitochondria-dependent apoptosis. EMBO J 21: 1695-1703, 2002.
79. Tanswell AK and Freeman BA. Pulmonary antioxidant enzyme maturation in the fetal and neonatal rat. I. Developmental profiles. Pediatr Res 18: 584-587, 1984.
80. Taylor RN, Crombleholme WR, Friedman SA, Jones LA, Casal DC, and Roberts JM. High plasma cellular fibronectin levels correlate with biochemical and clinical features of preeclampsia but cannot be attributed to hypertension alone. Am J Obstet Gynecol 165: 895-901, 1991.
81. Wollman EE, d'Auriol L, Rimsky L, Shaw A, Jacquot JP, Wingfield P, Graber P, Dessarps F, Robin P, Galibert F, et al. Cloning and expression of a cDNA for human thioredoxin. J Biol Chem 263: 15506-15512, 1988.
82. Zhong L and Holmgren A. Essential role of selenium in the catalytic activities of mammalian thioredoxin reductase revealed by characterization of recombinant enzymes with selenocysteine mutations. J Biol Chem 275: 18121-18128, 2000.
83. Zhong L, Arner ES, and Holmgren A. Structure and mechanism of mammalian thioredoxin reductase: the active site is a redox-active selenolthiol/selenenylsulfide formed from the conserved cysteine-selenocysteine sequence. Proc Natl Acad Sci U S A 97: 5854-5859, 2000.