-
1
-
-
0030021968
-
Intracellular inactivation of the hepatitis B virus by cytotoxic T lymphocytes
-
Guidotti LG et al. Intracellular inactivation of the hepatitis B virus by cytotoxic T lymphocytes. Immunity 1996; 4: 25-36.
-
(1996)
Immunity
, vol.4
, pp. 25-36
-
-
Guidotti, L.G.1
-
2
-
-
0030997139
-
Interleukin-12 inhibits hepatitis B virus replication in transgenic mice
-
Cavanaugh VJ, Guidotti LG, Chisari FV. Interleukin-12 inhibits hepatitis B virus replication in transgenic mice. J Virol 1997; 71: 3236-3243.
-
(1997)
J. Virol.
, vol.71
, pp. 3236-3243
-
-
Cavanaugh, V.J.1
Guidotti, L.G.2
Chisari, F.V.3
-
3
-
-
0036839079
-
Interleukin-18 inhibits hepatitis B virus replication in the livers of transgenic mice
-
Kimura K et al. Interleukin-18 inhibits hepatitis B virus replication in the livers of transgenic mice. J Virol 2002; 76: 10702-10707.
-
(2002)
J. Virol.
, vol.76
, pp. 10702-10707
-
-
Kimura, K.1
-
4
-
-
0036191172
-
Interferon-gamma inhibits replication of sub-genomic and genomic hepatitis C virus RNAs
-
Frese M et al. Interferon-gamma inhibits replication of sub-genomic and genomic hepatitis C virus RNAs. Hepatology 2002; 35: 694-703.
-
(2002)
Hepatology
, vol.35
, pp. 694-703
-
-
Frese, M.1
-
5
-
-
0032825042
-
Interferon gene transfer by a hepatitis B virus vector efficiently suppresses wild-type virus infection
-
Protzer U et al. Interferon gene transfer by a hepatitis B virus vector efficiently suppresses wild-type virus infection. Proc Natl Acad Sci USA 1999; 96: 10818-10823.
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 10818-10823
-
-
Protzer, U.1
-
6
-
-
0026720075
-
Tight control of gene expression in mammalian cells by tetracycline-responsive promoters
-
Gossen M, Bujard H. Tight control of gene expression in mammalian cells by tetracycline-responsive promoters. Proc Natl Acad Sci USA 1992; 89: 5547-5551.
-
(1992)
Proc. Natl. Acad. Sci. USA
, vol.89
, pp. 5547-5551
-
-
Gossen, M.1
Bujard, H.2
-
7
-
-
0029022369
-
Transcriptional activation by tetracyclines in mammalian cells
-
Gossen M et al. Transcriptional activation by tetracyclines in mammalian cells. Science 1995; 268: 1766-1769.
-
(1995)
Science
, vol.268
, pp. 1766-1769
-
-
Gossen, M.1
-
8
-
-
0029075822
-
Co-regulation of two gene activities by tetracycline via a bidirectional promoter
-
Baron U, Freundlieb S, Gossen M, Bujard H. Co-regulation of two gene activities by tetracycline via a bidirectional promoter. Nucleic Acids Res 1995; 23: 3605-3606.
-
(1995)
Nucleic Acids Res.
, vol.23
, pp. 3605-3606
-
-
Baron, U.1
Freundlieb, S.2
Gossen, M.3
Bujard, H.4
-
9
-
-
0029763587
-
Doxycycline-mediated quantitative and tissue-specific control of gene expression in transgenic mice
-
Kistner A et al. Doxycycline-mediated quantitative and tissue-specific control of gene expression in transgenic mice. Proc Natl Acad Sci USA 1996; 93: 10933-10938.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 10933-10938
-
-
Kistner, A.1
-
10
-
-
0035089060
-
Long-term, noninvasive imaging of regulated gene expression in living mice
-
Hasan MT et al. Long-term, noninvasive imaging of regulated gene expression in living mice. Genesis 2001; 29: 116-122.
-
(2001)
Genesis
, vol.29
, pp. 116-122
-
-
Hasan, M.T.1
-
11
-
-
0034608802
-
Exploring the sequence space for tetracycline-dependent transcriptional activators: Novel mutations yield expanded range and sensitivity
-
Urlinger S et al. Exploring the sequence space for tetracycline-dependent transcriptional activators: novel mutations yield expanded range and sensitivity. Proc Natl Acad Sci USA 2000; 97: 7963-7968.
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 7963-7968
-
-
Urlinger, S.1
-
12
-
-
0034581163
-
Tet repressor-based system for regulated gene expression in eukaryotic cells: Principles and advances
-
Baron U, Bujard H. Tet repressor-based system for regulated gene expression in eukaryotic cells: principles and advances. Methods Enzymol 2000; 327: 401-421.
-
(2000)
Methods Enzymol.
, vol.327
, pp. 401-421
-
-
Baron, U.1
Bujard, H.2
-
13
-
-
0036956875
-
Studying gene function in eukaryotes by conditional gene inactivation
-
Gossen M, Bujard H. Studying gene function in eukaryotes by conditional gene inactivation. Annu Rev Genet 2002; 36: 153-173.
-
(2002)
Annu. Rev. Genet.
, vol.36
, pp. 153-173
-
-
Gossen, M.1
Bujard, H.2
-
14
-
-
0031660671
-
Two novel adenovirus vector systems permitting regulated protein expression in gene transfer experiments
-
Molin M et al. Two novel adenovirus vector systems permitting regulated protein expression in gene transfer experiments. J Virol 1998; 72: 8358-8361.
-
(1998)
J. Virol.
, vol.72
, pp. 8358-8361
-
-
Molin, M.1
-
15
-
-
0032893035
-
A single adenovirus vector mediates doxycycline-controlled expression of tyrosine hydroxylase in brain grafts of human neural progenitors
-
Corti O et al. A single adenovirus vector mediates doxycycline-controlled expression of tyrosine hydroxylase in brain grafts of human neural progenitors. Nat Biotechnol 1999; 17: 349-354.
-
(1999)
Nat. Biotechnol.
, vol.17
, pp. 349-354
-
-
Corti, O.1
-
16
-
-
0034124055
-
Adenoviral vector which delivers FasL-GFP fusion protein regulated by the tet-inducible expression system
-
Rubinchik S et al. Adenoviral vector which delivers FasL-GFP fusion protein regulated by the tet-inducible expression system. Gene Therapy 2000; 7: 875-885.
-
(2000)
Gene Therapy
, vol.7
, pp. 875-885
-
-
Rubinchik, S.1
-
17
-
-
0035709608
-
Regulated and prolonged expression of mIFN(alpha) in immunocompetent mice mediated by a helper-dependent adenovirus vector
-
Aurisicchio L et al. Regulated and prolonged expression of mIFN(alpha) in immunocompetent mice mediated by a helper-dependent adenovirus vector. Gene Therapy 2001; 8: 1817-1825.
-
(2001)
Gene Therapy
, vol.8
, pp. 1817-1825
-
-
Aurisicchio, L.1
-
18
-
-
0032415073
-
Inducible long-term gene expression in brain with adeno-associated virus gene transfer
-
Haberman RP, McCown TJ, Samulski RJ. Inducible long-term gene expression in brain with adeno-associated virus gene transfer. Gene Therapy 1998; 5: 1604-1611.
-
(1998)
Gene Therapy
, vol.5
, pp. 1604-1611
-
-
Haberman, R.P.1
McCown, T.J.2
Samulski, R.J.3
-
19
-
-
0035666134
-
Insulators coupled to a minimal bidirectional tet cassette for tight regulation of rAAV-mediated gene transfer in the mammalian brain
-
Fitzsimons HL, McKenzie JM, During MJ. Insulators coupled to a minimal bidirectional tet cassette for tight regulation of rAAV-mediated gene transfer in the mammalian brain. Gene Therapy 2001; 8: 1675-1681.
-
(2001)
Gene Therapy
, vol.8
, pp. 1675-1681
-
-
Fitzsimons, H.L.1
McKenzie, J.M.2
During, M.J.3
-
20
-
-
0036171329
-
Tightly regulated long-term erythropoietin expression in vivo using tet-inducible recombinant adeno-associated viral vectors
-
Rendahl KG et al. Tightly regulated long-term erythropoietin expression in vivo using tet-inducible recombinant adeno-associated viral vectors. Hum Gene Ther 2002; 13: 335-342.
-
(2002)
Hum. Gene Ther.
, vol.13
, pp. 335-342
-
-
Rendahl, K.G.1
-
21
-
-
0029656105
-
Self-contained, tetracycline-regulated retroviral vector system for gene delivery to mammalian cells
-
Paulus W et al. Self-contained, tetracycline-regulated retroviral vector system for gene delivery to mammalian cells. J Virol 1996; 70: 62-67.
-
(1996)
J. Virol.
, vol.70
, pp. 62-67
-
-
Paulus, W.1
-
22
-
-
0030001394
-
Rapid retroviral delivery of tetracycline-inducible genes in a single autoregulatory cassette
-
Hofmann A, Nolan GP, Blau HM. Rapid retroviral delivery of tetracycline-inducible genes in a single autoregulatory cassette. Proc Natl Acad Sci USA 1996; 93: 5185-5190.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 5185-5190
-
-
Hofmann, A.1
Nolan, G.P.2
Blau, H.M.3
-
23
-
-
0033759915
-
Development of multigene and regulated lentivirus vectors
-
Reiser J, Lai Z, Zhang XY, Brady RO. Development of multigene and regulated lentivirus vectors. J Virol 2000; 74: 10589-10599.
-
(2000)
J. Virol.
, vol.74
, pp. 10589-10599
-
-
Reiser, J.1
Lai, Z.2
Zhang, X.Y.3
Brady, R.O.4
-
25
-
-
0030571056
-
Inducible gene expression from defective herpes simplex virus vectors using the tetracycline-responsive promoter system
-
Ho DY, McLaughlin JR, Sapolsky RM. Inducible gene expression from defective herpes simplex virus vectors using the tetracycline-responsive promoter system. Brain Res Mol Brain Res 1996; 41: 200-209.
-
(1996)
Brain Res. Mol. Brain Res.
, vol.41
, pp. 200-209
-
-
Ho, D.Y.1
McLaughlin, J.R.2
Sapolsky, R.M.3
-
26
-
-
0032478271
-
A simplified system for generating recombinant adenoviruses
-
He TC et al. A simplified system for generating recombinant adenoviruses. Proc Natl Acad Sci USA 1998; 95: 2509-2514.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 2509-2514
-
-
He, T.C.1
-
27
-
-
0034068781
-
Insulation from viral transcriptional regulatory elements improves inducible transgene expression from adenovirus vectors in vitro and in vivo
-
Steinwaerder DS, Lieber A. Insulation from viral transcriptional regulatory elements improves inducible transgene expression from adenovirus vectors in vitro and in vivo. Gene Therapy 2000; 7: 556-567.
-
(2000)
Gene Therapy
, vol.7
, pp. 556-567
-
-
Steinwaerder, D.S.1
Lieber, A.2
-
28
-
-
0035114101
-
Creation of a new transgene cloning site near the right ITR of Ad5 results in reduced enhancer interference with tissue-specific and regulatable promoters
-
Rubinchik S et al. Creation of a new transgene cloning site near the right ITR of Ad5 results in reduced enhancer interference with tissue-specific and regulatable promoters. Gene Therapy 2001; 8: 247-253.
-
(2001)
Gene Therapy
, vol.8
, pp. 247-253
-
-
Rubinchik, S.1
-
29
-
-
0028217613
-
The 5′ flanking region of the rat LAP (C/EBP beta) gene can direct high-level, position-independent, copy number-dependent expression in multiple tissues in transgenic mice
-
Talbot D, Descombes P, Schibler U. The 5′ flanking region of the rat LAP (C/EBP beta) gene can direct high-level, position-independent, copy number-dependent expression in multiple tissues in transgenic mice. Nucleic Acids Res 1994; 22: 756-766.
-
(1994)
Nucleic Acids Res.
, vol.22
, pp. 756-766
-
-
Talbot, D.1
Descombes, P.2
Schibler, U.3
-
31
-
-
0025800127
-
Site-directed mutagenesis of hepatocyte nuclear factor (HNF) binding sites in the mouse transthyretin (TTR) promoter reveal synergistic interactions with its enhancer region
-
Costa RH, Grayson DR. Site-directed mutagenesis of hepatocyte nuclear factor (HNF) binding sites in the mouse transthyretin (TTR) promoter reveal synergistic interactions with its enhancer region. Nucleic Acids Res 1991; 19: 4139-4145.
-
(1991)
Nucleic Acids Res.
, vol.19
, pp. 4139-4145
-
-
Costa, R.H.1
Grayson, D.R.2
-
32
-
-
0037564287
-
Primary human hepatocytes - A valuable tool for investigation of apoptosis and hepatitis B virus infection
-
Schulze-Bergkamen H et al. Primary human hepatocytes - a valuable tool for investigation of apoptosis and hepatitis B virus infection. J Hepatol 2003; 38: 736-744.
-
(2003)
J. Hepatol.
, vol.38
, pp. 736-744
-
-
Schulze-Bergkamen, H.1
-
33
-
-
0041842623
-
Use of the tetracycline system for inducible protein synthesis in the kidney
-
Gallagher AR et al. Use of the tetracycline system for inducible protein synthesis in the kidney. J Am Soc Nephrol 2003; 14: 2042-2051.
-
(2003)
J. Am. Soc. Nephrol.
, vol.14
, pp. 2042-2051
-
-
Gallagher, A.R.1
-
34
-
-
0031252491
-
Visualizing gene expression in living mammals using a bioluminescent reporter
-
Contag CH et al. Visualizing gene expression in living mammals using a bioluminescent reporter. Photochem Photobiol 1997; 66: 523-531.
-
(1997)
Photochem. Photobiol.
, vol.66
, pp. 523-531
-
-
Contag, C.H.1
-
35
-
-
0034019281
-
Regulatable systems: Applications in gene therapy and replicating viruses
-
Agha-Mohammadi S, Lotze MT. Regulatable systems: applications in gene therapy and replicating viruses. J Clin Invest 2000; 105: 1177-1183.
-
(2000)
J. Clin. Invest.
, vol.105
, pp. 1177-1183
-
-
Agha-Mohammadi, S.1
Lotze, M.T.2
-
36
-
-
0033981631
-
Regulated gene expression systems
-
Clackson T. Regulated gene expression systems. Gene Therapy 2000; 7: 120-125.
-
(2000)
Gene Therapy
, vol.7
, pp. 120-125
-
-
Clackson, T.1
-
38
-
-
0035401096
-
Adenoviral vector-mediated gene transfer for human gene therapy
-
Breyer B et al. Adenoviral vector-mediated gene transfer for human gene therapy. Curr Gene Ther 2001; 1: 149-162.
-
(2001)
Curr. Gene Ther.
, vol.1
, pp. 149-162
-
-
Breyer, B.1
-
39
-
-
0031838298
-
Switching transgene expression in the brain using an adenoviral tetracycline-regulatable system
-
Harding TC et al. Switching transgene expression in the brain using an adenoviral tetracycline-regulatable system. Nat Biotechnol 1998; 16: 553-555.
-
(1998)
Nat. Biotechnol.
, vol.16
, pp. 553-555
-
-
Harding, T.C.1
-
40
-
-
0036792499
-
Evaluation of Tet-on system to avoid transgene down-regulation in ex vivo gene transfer to the CNS
-
Johansen J et al. Evaluation of Tet-on system to avoid transgene down-regulation in ex vivo gene transfer to the CNS. Gene Therapy 2002; 9: 1291-1301.
-
(2002)
Gene Therapy
, vol.9
, pp. 1291-1301
-
-
Johansen, J.1
-
41
-
-
18244382853
-
Stringent control of gene expression in vivo by using novel doxycycline-dependent trans-activators
-
Lamartina S et al. Stringent control of gene expression in vivo by using novel doxycycline-dependent trans activators. Hum Gene Ther 2002; 13: 199-210.
-
(2002)
Hum. Gene Ther.
, vol.13
, pp. 199-210
-
-
Lamartina, S.1
-
42
-
-
0042909334
-
Generating conditional mouse mutants via tetracyclin-controlled gene expression
-
Hofken MH, Dvan Deursen J (eds) Humana Press Inc.: Totowa, NJ
-
Schönig K, Bujard H. Generating conditional mouse mutants via tetracyclin-controlled gene expression. In: Hofken MH, Dvan Deursen J (eds) Transgenic Mouse - Methods and Protocols. Humana Press Inc.: Totowa, NJ, 2002, pp 69-104.
-
(2002)
Transgenic Mouse - Methods and Protocols
, pp. 69-104
-
-
Schönig, K.1
Bujard, H.2
-
43
-
-
0034159971
-
The tetracycline-responsive promoter contains functional interferon-inducible response elements
-
Rang A, Will H. The tetracycline-responsive promoter contains functional interferon-inducible response elements. Nucleic Acids Res 2000; 28: 1120-1125.
-
(2000)
Nucleic Acids Res.
, vol.28
, pp. 1120-1125
-
-
Rang, A.1
Will, H.2
-
44
-
-
0035080357
-
Genetic heterogeneity in the toxicity to systemic adenoviral gene transfer of interleukin-12
-
Mazzolini G et al. Genetic heterogeneity in the toxicity to systemic adenoviral gene transfer of interleukin-12. Gene Therapy 2001; 8: 259-267.
-
(2001)
Gene Therapy
, vol.8
, pp. 259-267
-
-
Mazzolini, G.1
-
45
-
-
0033088239
-
In vivo manipulation of interleukin-2 expression by a retroviral tetracycline (tet)-regulated system
-
Pitzer C et al. In vivo manipulation of interleukin-2 expression by a retroviral tetracycline (tet)-regulated system. Cancer Gene Ther 1999; 6: 139-146.
-
(1999)
Cancer Gene Ther.
, vol.6
, pp. 139-146
-
-
Pitzer, C.1
-
46
-
-
0035061224
-
Tetracycline-regulatable adenovirus vectors: Pharmacologic properties and clinical potential
-
Nakagawa S, Massie B, Hawley RG. Tetracycline-regulatable adenovirus vectors: pharmacologic properties and clinical potential. Eur J Pharm Sci 2001; 13: 53-60.
-
(2001)
Eur. J. Pharm. Sci.
, vol.13
, pp. 53-60
-
-
Nakagawa, S.1
Massie, B.2
Hawley, R.G.3
-
47
-
-
0031924393
-
Inhibition of hepatitis B virus replication during adenovirus and cytomegalovirus infections in transgenic mice
-
Cavanaugh VJ, Guidotti LG, Chisari FV. Inhibition of hepatitis B virus replication during adenovirus and cytomegalovirus infections in transgenic mice. J Virol 1998; 72: 2630-2637.
-
(1998)
J. Virol.
, vol.72
, pp. 2630-2637
-
-
Cavanaugh, V.J.1
Guidotti, L.G.2
Chisari, F.V.3
-
48
-
-
0343569832
-
Endotoxin stimulates liver macrophages to release mediators that inhibit an early step in hepadnavirus replication
-
Klöcker U, Schultz U, Schaller H, Protzer U. Endotoxin stimulates liver macrophages to release mediators that inhibit an early step in hepadnavirus replication. J Virol 2000; 74: 5525-5533.
-
(2000)
J. Virol.
, vol.74
, pp. 5525-5533
-
-
Klöcker, U.1
Schultz, U.2
Schaller, H.3
Protzer, U.4
-
50
-
-
0033998463
-
Intrahepatic induction of alpha/beta interferon eliminates viral RNA-containing capsids in hepatitis B virus transgenic mice
-
Wieland SF, Guidotti LG, Chisari FV. Intrahepatic induction of alpha/beta interferon eliminates viral RNA-containing capsids in hepatitis B virus transgenic mice. J Virol 2000; 74: 4165-4173.
-
(2000)
J. Virol.
, vol.74
, pp. 4165-4173
-
-
Wieland, S.F.1
Guidotti, L.G.2
Chisari, F.V.3
-
51
-
-
0035033218
-
Transfer of hepatitis B virus genome by adenovirus vectors into cultured cells and mice: Crossing the species barrier
-
Sprinzl MF, Oberwinkler H, Schaller H, Protzer U. Transfer of hepatitis B virus genome by adenovirus vectors into cultured cells and mice: crossing the species barrier. J Virol 2001; 75: 5108-5118.
-
(2001)
J. Virol.
, vol.75
, pp. 5108-5118
-
-
Sprinzl, M.F.1
Oberwinkler, H.2
Schaller, H.3
Protzer, U.4
-
52
-
-
0347928672
-
Inhibition of hepatitis B virus replication by drug-induced depletion of nucleocapsids
-
Deres K et al. Inhibition of hepatitis B virus replication by drug-induced depletion of nucleocapsids. Science 2003; 299: 893-896.
-
(2003)
Science
, vol.299
, pp. 893-896
-
-
Deres, K.1
|