The nucleotide switch in Cdc42 modulates coupling between the GTPase-binding and allosteric equilibria of Wiskott-Aldrich syndrome protein

Proceedings of the National Academy of Sciences of the United States of America

Volumn 102, Issue 16, 2005, Pages 5685-5690

  Leung, Daisy W ^a   Rosen, Michael K ^a  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

Allostery; Signal transduction

Indexed keywords

ACTIN RELATED PROTEIN 2; ACTIN RELATED PROTEIN 3; GUANOSINE DIPHOSPHATE; GUANOSINE TRIPHOSPHATASE; GUANOSINE TRIPHOSPHATE; NUCLEOTIDE; PROTEIN CDC42; RAS PROTEIN; RHO GUANINE NUCLEOTIDE BINDING PROTEIN; WISKOTT ALDRICH SYNDROME PROTEIN;

ALLOSTERISM; ARTICLE; BINDING AFFINITY; COMPARATIVE STUDY; EQUILIBRIUM CONSTANT; MEMBRANE; MODEL; NUCLEIC ACID BASE SUBSTITUTION; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION;

ACTIN-RELATED PROTEIN 2; ACTIN-RELATED PROTEIN 3; ALLOSTERIC REGULATION; CDC42 GTP-BINDING PROTEIN; CYTOSKELETAL PROTEINS; HUMANS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PROTEIN STRUCTURE, TERTIARY; PROTEINS; WISKOTT-ALDRICH SYNDROME PROTEIN;

EID: 17644377914     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0406472102     Document Type: Article

References (32)

1. Bourne, H. R. (1995) Philos. Trans. K. Soc. London B 349, 283-289.
2. Buchwald, G., Hostinova, E., Rudolph, M. G., Kraemer, A., Sickmann, A., Meyer, H. E., Scheffzek, K. & Wittinghofer, A. (2001) Mol. Cell. Biol. 21, 5179-5189.
3. Buck, M., Xu, W. & Rosen, M. K. (2001) Biochemistry 40, 14115-14122.
4. Hoffman, G. R. & Cerione, R. A. (2000) Cell 102, 403-406.
5. Vetter, I. R. & Wittinghofer, A. (2001) Science 294, 1299-1304.
6. Lei, M., Lu, W., Meng, W., Parrini, M. C., Eck, M. J., Mayer, B. J. & Harrison, S. C. (2000) Cell 102, 387-397.
7. Etienne-Manneville, S. & Hall, A. (2002) Nature 420, 629-635.
8. Higgs, H. N. & Pollard, T. D. (2001) Annu. Rev. Biochem. 70, 649-676.
9. Kim, A. S., Kakalis, L. T., Abdul-Manan, N., Liu, G. A & Rosen, M. K. (2000) Nature 404, 151-158.
10. Buck, M., Xu, W. & Rosen, M. K. (2004) J. Mol. Biol. 338, 271-285.
11. Abdul-Manan, N., Aghazadeh, B., Liu, G. A., Majumdar, A., Ouerfelli, O., Siminovitch, K. A. & Rosen, M. K. (1999) Nature 399, 379-383.
12. Higgs, H. N., Blanchoin, L. & Pollard, T. D. (1999) Biochemistry 38, 15212-15222.
13. Pardee, J. D. & Spudich, J. A. (1982) Methods Enzymol. 85, 164-181.
14. Pace, C. N. (1990) Trends Biotechnol. 8, 93-98.
15. Marchand, J. B., Kaiser, D. A., Pollard, T. D. & Higgs, H. N. (2001) Nat. Cell Biol. 3, 76-82.
16. Rudolph, M. G., Linnemann, T., Grunewald, P., Wittinghofer, A., Vetter, I. R. & Herrmann, C. (2001) J. Biol. Chem. 276, 23914-23921.
17. Seth, A., Otomo, T., Yin, H. L. & Rosen, M. K. (2003) Biochemistry 42, 3997-4008.
18. Muhandiram, D. R. & Kay, L. E. (1994) J. Magn. Reson. Ser. B 103, 203-216.
19. Delaglio, F., Grzesiek, S., Vuister, G. W., Zhu, G., Pfeifer, J. & Bax, A. (1995) J. Biomol. NMR 6, 277-293.
20. Johnson, B. A. & Blevins, R. A. (1994) J. Biomol. NMR 4, 603-614.
21. Monod, J., Wyman, J. & Changeux, J. P. (1965) J. Mol. Biol. 12, 88-118.
22. Fersht, A. (1999) Structure and Mechanism in Protein Science: A Guide to Enzyme Catalysis and Protein Folding (Freeman, New York).
23. Prehoda, K. E., Scott, J. A., Mullins, R. D. & Lim, W. A. (2000) Science 290, 801-806.
24. Rohatgi, R., Ho, H. Y. & Kirschner, M. W. (2000) J. Cell Biol. 150, 1299-1310.
25. Peterson, J. R., Bickford, L. C., Morgan, D., Kim, A. S., Ouerfelli, O., Kirschner, M. W. & Rosen, M. K. (2004) Nat. Struct. Mol. Biol. 11, 747-755.
26. Ho, H. Y., Rohatgi, R., Lebensohn, A. M., Le, M., Li, J., Gygi, S. P. & Kirschner, M. W. (2004) Cell 118, 203-216.
27. Martinez-Quiles, N., Rohatgi, R., Anton, I. M., Medina, M., Seville, S. P., Miki, H., Yamaguchi, H., Takenawa, T., Hartwig, J. H., Geha, R. S. & Ramesh, N. (2001) Nat. Cell Biol. 3, 484-491.
28. Hatley, M. E., Lockless, S. W., Gibson, S. K., Gilman, A. G. & Ranganathan, R. (2003) Proc. Natl. Acad. Sci. USA 100, 14445-14450.
29. Labno, C. M., Lewis, C. M., You, D., Leung, D. W., Takesono, A., Kamberos, N., Seth, A., Finkelstein, L. D., Rosen, M. K., Schwartzberg, P. L. & Burkhardt, J. K. (2003) Curr. Biol. 13, 1619-1624.
30. Cannon, J. L. & Burkhardt, J. K. (2002) Immunol. Rev. 186, 90-99.
31. Cannon, J. L., Labno, C. M., Bosco, G., Seth, A., McGavin, M. H., Siminovitch, K. A., Rosen, M. K. & Burkhardt, J. K. (2001) Immunity 15, 249-259.
32. Hoffman, G. R., Nassar, N. & Cerione, R. A. (2000) Cell 100, 345-356.