The origins of high-affinity enzyme binding to an extrahelical DNA base

Biochemistry

Volumn 44, Issue 16, 2005, Pages 5949-5959

  Krosky, Daniel J ^a   Song, Fenhong ^b   Stivers, James T ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b NATIONAL INSTITUTE OF STANDARDS AND TECHNOLOGY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMISTRY; CATALYSIS; DNA; FLUORESCENCE; HYDROGEN BONDS; REACTION KINETICS; THERMODYNAMICS;

DUPLEX STRUCTURE; ENZYME BINDING; FLIPPING MECHANISM; URACIL DNA GLYCOSYLASE (UDG);

ENZYMES;

ADENINE; CURVED DNA; DNA BASE; DOUBLE STRANDED DNA; POLYDEOXYRIBONUCLEOTIDE SYNTHASE; URACIL DNA GLYCOSYLTRANSFERASE;

ARTICLE; BASE PAIRING; CATALYSIS; ENZYME ACTIVE SITE; ENZYME BINDING; ENZYME SUBSTRATE COMPLEX; HYDROGEN BOND; MATHEMATICAL ANALYSIS; NONHUMAN; PRIORITY JOURNAL; THERMODYNAMICS;

BASE PAIRING; BASE SEQUENCE; BINDING SITES; DNA; DNA DAMAGE; DNA GLYCOSYLASES; DNA REPAIR; ESCHERICHIA COLI; HYDROGEN BONDING; KINETICS; MODELS, MOLECULAR; NUCLEIC ACID CONFORMATION; SPECTROMETRY, FLUORESCENCE; SUBSTRATE SPECIFICITY; THERMODYNAMICS; URACIL-DNA GLYCOSIDASE;

EID: 17644366825     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi050084u     Document Type: Article

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