메뉴 건너뛰기




Volumn 39, Issue 3, 2000, Pages 211-220

Kindling alters the anticonvulsant efficacy of phenytoin in Wistar rats

Author keywords

Anticonvulsant drugs; Epilepsy; Epileptogenesis; Fosphenytoin; Pharmacoresistance

Indexed keywords

FOSPHENYTOIN SODIUM; PHENYTOIN; PRODRUG;

EID: 0342264691     PISSN: 09201211     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0920-1211(00)00100-5     Document Type: Article
Times cited : (22)

References (26)
  • 1
    • 0017846870 scopus 로고
    • Effects of phenobarbital and SC-13504 on partially kindled seizures in rats
    • Albertson T., Peterson S., Stark L. Effects of phenobarbital and SC-13504 on partially kindled seizures in rats. Exp. Neurol. 61:1978;270-280.
    • (1978) Exp. Neurol. , vol.61 , pp. 270-280
    • Albertson, T.1    Peterson, S.2    Stark, L.3
  • 2
    • 0019461510 scopus 로고
    • The anticonvulsant effects of diazepam and phenobarbital in prekindled and kindled seizures in rats
    • Albertson T.E., Peterson S.L., Stark L.G. The anticonvulsant effects of diazepam and phenobarbital in prekindled and kindled seizures in rats. Neuropharmacology. 20:1981;597-603.
    • (1981) Neuropharmacology , vol.20 , pp. 597-603
    • Albertson, T.E.1    Peterson, S.L.2    Stark, L.G.3
  • 3
    • 0020695919 scopus 로고
    • Effects of carbamazepine, clonazepam, and phenytoin on seizure threshold in amygdala and cortex
    • Albright P.S. Effects of carbamazepine, clonazepam, and phenytoin on seizure threshold in amygdala and cortex. Exp. Neurol. 79:1983;11-17.
    • (1983) Exp. Neurol. , vol.79 , pp. 11-17
    • Albright, P.S.1
  • 4
    • 0031689439 scopus 로고    scopus 로고
    • Characterization of phenytoin-resistant kindled rats, a new model of drug-resistant partial epilepsy: Comparison of inbred strains
    • Cramer S., Ebert U., Löscher W. Characterization of phenytoin-resistant kindled rats, a new model of drug-resistant partial epilepsy: comparison of inbred strains. Epilepsia. 39:1998;1046-1053.
    • (1998) Epilepsia , vol.39 , pp. 1046-1053
    • Cramer, S.1    Ebert, U.2    Löscher, W.3
  • 5
    • 0030929440 scopus 로고    scopus 로고
    • Phenytoin's effect on the spread of seizure activity in the amygdala kindling model
    • Ebert U., Cramer S., Löscher W. Phenytoin's effect on the spread of seizure activity in the amygdala kindling model. Naunyn Schmiedeberg's Arch. Pharmacol. 356:1997;341-347.
    • (1997) Naunyn Schmiedeberg's Arch. Pharmacol. , vol.356 , pp. 341-347
    • Ebert, U.1    Cramer, S.2    Löscher, W.3
  • 6
    • 0033045047 scopus 로고    scopus 로고
    • Characterization of phenytoin-resistant rats, a new model of drug-resistant partial epilepsy: Influence of experimental and environmental factors
    • Ebert U., Rundfeldt C., Lehmann H., Löscher W. Characterization of phenytoin-resistant rats, a new model of drug-resistant partial epilepsy: influence of experimental and environmental factors. Epilepsy Res. 33:1999;199-215.
    • (1999) Epilepsy Res. , vol.33 , pp. 199-215
    • Ebert, U.1    Rundfeldt, C.2    Lehmann, H.3    Löscher, W.4
  • 7
    • 0344628691 scopus 로고    scopus 로고
    • Characterization of phenytoin-resistant kindled rats, a new model of drug-resistant partial epilepsy: Influence of genetic factors
    • Ebert U., Löscher W. Characterization of phenytoin-resistant kindled rats, a new model of drug-resistant partial epilepsy: influence of genetic factors. Epilepsy Res. 33:1999;217-226.
    • (1999) Epilepsy Res. , vol.33 , pp. 217-226
    • Ebert, U.1    Löscher, W.2
  • 8
    • 0010047912 scopus 로고
    • Epidemiology of intractable epilepsy in adults
    • S.I. Johannessen, L. Gram, M. Sillanpää, & T. Tomson. Petersfield: Wrightson Biomedical Publishing Ltd
    • Forsgren L. Epidemiology of intractable epilepsy in adults. Johannessen S.I., Gram L., Sillanpää M., Tomson T. Intractable Epilepsy. 1995;25-40 Wrightson Biomedical Publishing Ltd, Petersfield.
    • (1995) Intractable Epilepsy , pp. 25-40
    • Forsgren, L.1
  • 9
    • 0019854869 scopus 로고
    • The effect of interstimulation interval on the assessment and stability of kindled seizure threshold
    • Freeman F.G., Jarvis M.F. The effect of interstimulation interval on the assessment and stability of kindled seizure threshold. Brain Res. Bull. 7:1981;629-633.
    • (1981) Brain Res. Bull. , vol.7 , pp. 629-633
    • Freeman, F.G.1    Jarvis, M.F.2
  • 10
    • 0021260688 scopus 로고
    • Anticonvulsant effect of primidone in the gerbil. Time course and significance of the active metabolites
    • Frey H.-H., Löscher W., Reiche R., Schultz D. Anticonvulsant effect of primidone in the gerbil. Time course and significance of the active metabolites. Pharmacology. 28:1984;329-335.
    • (1984) Pharmacology , vol.28 , pp. 329-335
    • Frey, H.-H.1    Löscher, W.2    Reiche, R.3    Schultz, D.4
  • 11
    • 0029161428 scopus 로고
    • Kindling increases the sensitivity of rats to adverse effects of certain antiepileptic drugs
    • Hönack D., Löscher W. Kindling increases the sensitivity of rats to adverse effects of certain antiepileptic drugs. Epilepsia. 36:1995;763-771.
    • (1995) Epilepsia , vol.36 , pp. 763-771
    • Hönack, D.1    Löscher, W.2
  • 12
    • 0343223353 scopus 로고
    • Electrophysiological effects of antiepileptic drugs
    • H.-H. Frey, & D. Janz. Berlin: Springer
    • Jurna I. Electrophysiological effects of antiepileptic drugs. Frey H.-H., Janz D. Antiepileptic Drugs. 1985;611-658 Springer, Berlin.
    • (1985) Antiepileptic Drugs , pp. 611-658
    • Jurna, I.1
  • 13
    • 0343990077 scopus 로고    scopus 로고
    • Animal models of intractable epilepsy
    • Löscher W. Animal models of intractable epilepsy. Prog. Neurobiol. 53:1997;239-258.
    • (1997) Prog. Neurobiol. , vol.53 , pp. 239-258
    • Löscher, W.1
  • 14
    • 0026075949 scopus 로고
    • Kindling as a model of drug-resistant partial epilepsy: Selection of phenytoin-resistant and nonresistant rats
    • Löscher W., Rundfeldt C. Kindling as a model of drug-resistant partial epilepsy: selection of phenytoin-resistant and nonresistant rats. J. Pharmacol. Exp. Ther. 258:1991;483-489.
    • (1991) J. Pharmacol. Exp. Ther. , vol.258 , pp. 483-489
    • Löscher, W.1    Rundfeldt, C.2
  • 15
    • 0023897574 scopus 로고
    • Which animal models should be used in the search for new antiepileptic drugs? A proposal based on experimental and clinical considerations
    • Löscher W., Schmidt D. Which animal models should be used in the search for new antiepileptic drugs? A proposal based on experimental and clinical considerations. Epilepsy Res. 2:1988;145-181.
    • (1988) Epilepsy Res. , vol.2 , pp. 145-181
    • Löscher, W.1    Schmidt, D.2
  • 16
    • 0028220347 scopus 로고
    • Strategies in antiepileptic drug development: Is rational drug design superior to random screening and structural variation?
    • Löscher W., Schmidt D. Strategies in antiepileptic drug development: is rational drug design superior to random screening and structural variation? Epilepsy Res. 17:1994;95-134.
    • (1994) Epilepsy Res. , vol.17 , pp. 95-134
    • Löscher, W.1    Schmidt, D.2
  • 17
    • 0022455261 scopus 로고
    • Is amygdala kindling in rats a model for drug-resistant partial epilepsy?
    • Löscher W., Jäckel R., Czuczwar S.J. Is amygdala kindling in rats a model for drug-resistant partial epilepsy? Exp. Neurol. 93:1986;211-226.
    • (1986) Exp. Neurol. , vol.93 , pp. 211-226
    • Löscher, W.1    Jäckel, R.2    Czuczwar, S.J.3
  • 18
    • 0027242081 scopus 로고
    • Pharmacological characterization of phenytoin-resistant amygdala-kindled rats, a new model of drug-resistant partial epilepsy
    • Löscher W., Rundfeldt C., Hönack D. Pharmacological characterization of phenytoin-resistant amygdala-kindled rats, a new model of drug-resistant partial epilepsy. Epilepsy Res. 15:1993;207-219.
    • (1993) Epilepsy Res. , vol.15 , pp. 207-219
    • Löscher, W.1    Rundfeldt, C.2    Hönack, D.3
  • 19
    • 0031769296 scopus 로고    scopus 로고
    • Selection of phenytoin responders and nonresponders in male and female amygdala-kindled Sprague-Dawley rats
    • Löscher W., Cramer S., Ebert U. Selection of phenytoin responders and nonresponders in male and female amygdala-kindled Sprague-Dawley rats. Epilepsia. 39:1998a;1138-1147.
    • (1998) Epilepsia , vol.39 , pp. 1138-1147
    • Löscher, W.1    Cramer, S.2    Ebert, U.3
  • 20
    • 0345698731 scopus 로고    scopus 로고
    • Limbic epileptogenesis alters the anticonvulsant efficacy of phenytoin in Sprague-Dawley rats
    • Löscher W., Cramer S., Ebert U. Limbic epileptogenesis alters the anticonvulsant efficacy of phenytoin in Sprague-Dawley rats. Epilepsy Res. 31:1998b;175-186.
    • (1998) Epilepsy Res. , vol.31 , pp. 175-186
    • Löscher, W.1    Cramer, S.2    Ebert, U.3
  • 21
    • 0042929063 scopus 로고    scopus 로고
    • Anticonvulsant effect of fosphenytoin in amygdala-kindled rats: Comparison with phenytoin
    • Löscher W., Reissmüller E., Ebert U. Anticonvulsant effect of fosphenytoin in amygdala-kindled rats: comparison with phenytoin. Epilepsy Res. 30:1998c;69-76.
    • (1998) Epilepsy Res. , vol.30 , pp. 69-76
    • Löscher, W.1    Reissmüller, E.2    Ebert, U.3
  • 23
    • 0015309163 scopus 로고
    • Modification of seizure activity by electrical stimulation: II. Motor seizure
    • Racine R.J. Modification of seizure activity by electrical stimulation: II. Motor seizure. Electroencephalogr. Clin. Neurophysiol. 32:1972;281-294.
    • (1972) Electroencephalogr. Clin. Neurophysiol. , vol.32 , pp. 281-294
    • Racine, R.J.1
  • 24
    • 0025168396 scopus 로고
    • Phenytoin potently increases the threshold for focal seizures in amygdala-kindled rats
    • Rundfeldt C., Hönack D., Löscher W. Phenytoin potently increases the threshold for focal seizures in amygdala-kindled rats. Neuropharmacology. 29:1990;845-851.
    • (1990) Neuropharmacology , vol.29 , pp. 845-851
    • Rundfeldt, C.1    Hönack, D.2    Löscher, W.3
  • 25
    • 0024424210 scopus 로고
    • Pharmacology of ACC-9653 (phenytoin prodrug)
    • Smith R.D., Brown B.S., Maher R.W., Matier W.L. Pharmacology of ACC-9653 (phenytoin prodrug). Epilepsia. 30(Suppl. 2):1989;S15-S21.
    • (1989) Epilepsia , vol.30 , Issue.SUPPL. 2 , pp. 15-S21
    • Smith, R.D.1    Brown, B.S.2    Maher, R.W.3    Matier, W.L.4
  • 26
    • 0002429858 scopus 로고
    • Phenytoin-clinical use
    • R.H. Levy, R.H. Mattson, & B.S. Meldrum. New York: Raven Press
    • Wilder B.J. Phenytoin-clinical use. Levy R.H., Mattson R.H., Meldrum B.S. Antiepileptic Drugs. 4th edn. 1995;339-344 Raven Press, New York.
    • (1995) Antiepileptic Drugs 4th Edn. , pp. 339-344
    • Wilder, B.J.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.