메뉴 건너뛰기




Volumn 41, Issue SUPPL. 1, 2000, Pages 30-34

Concentration-effect studies with topiramate on selected enzymes and intermediates of the GABA shunt

Author keywords

Antiepileptic drugs; Epilepsy; GABA; Glutamate; Topiramate

Indexed keywords

4 AMINOBUTYRATE AMINOTRANSFERASE; 4 AMINOBUTYRIC ACID; 4 AMINOBUTYRIC ACID RECEPTOR; CARBONATE DEHYDRATASE; GLUTAMATE DECARBOXYLASE; GLUTAMATE RECEPTOR; GLUTAMIC ACID; GLUTAMINE; SODIUM; SODIUM CHANNEL; TOPIRAMATE;

EID: 0034087350     PISSN: 00139580     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1528-1157.2000.tb02168.x     Document Type: Article
Times cited : (29)

References (24)
  • 2
    • 0030710582 scopus 로고    scopus 로고
    • Topiramate: A review of its pharmacodynamic and pharmacokinetic properties and clinical efficacy in the management of epilepsy
    • Langtry HD, Gillis JC, Davis R. Topiramate: a review of its pharmacodynamic and pharmacokinetic properties and clinical efficacy in the management of epilepsy. Drugs 1997;54:752-73.
    • (1997) Drugs , vol.54 , pp. 752-773
    • Langtry, H.D.1    Gillis, J.C.2    Davis, R.3
  • 3
    • 0028221989 scopus 로고
    • Topiramate: Preclinical evaluation of a structurally novel anticonvulsant
    • Shank RP, Gardocki JF, Vaught JL, et al. Topiramate: preclinical evaluation of a structurally novel anticonvulsant. Epilepsia 1994; 35:450-60.
    • (1994) Epilepsia , vol.35 , pp. 450-460
    • Shank, R.P.1    Gardocki, J.F.2    Vaught, J.L.3
  • 4
    • 0029899076 scopus 로고    scopus 로고
    • Topiramate: A potent anticonvulsant in the amygdala-kindled rat
    • Wauquier A, Zhou S. Topiramate: a potent anticonvulsant in the amygdala-kindled rat. Epilepsy Res 1996;24:73-7.
    • (1996) Epilepsy Res , vol.24 , pp. 73-77
    • Wauquier, A.1    Zhou, S.2
  • 5
    • 1842422933 scopus 로고    scopus 로고
    • Effect of topiramate (TPM) on pentylenetetrazol (PTZ) seizure threshold
    • White US, Woodhead JH, Wolf HH. Effect of topiramate (TPM) on pentylenetetrazol (PTZ) seizure threshold. Epilepsia 1996;37 (suppl 5):26.
    • (1996) Epilepsia , vol.37 , Issue.5 SUPPL. , pp. 26
    • White, U.S.1    Woodhead, J.H.2    Wolf, H.H.3
  • 6
    • 0344625216 scopus 로고    scopus 로고
    • Anticonvulsant activity of topiramate and phenytoin in a rat model of ischaemia-induced epilepsy
    • Edmonds HL, Jiang JD, Zhang PY, Shank RP. Anticonvulsant activity of topiramate and phenytoin in a rat model of ischaemia-induced epilepsy. Life Sci 1996;59:PL127-31.
    • (1996) Life Sci , vol.59
    • Edmonds, H.L.1    Jiang, J.D.2    Zhang, P.Y.3    Shank, R.P.4
  • 7
    • 0028348398 scopus 로고
    • Inhibition by topiramate of seizures in spontaneously epileptic rats and DBA/2 mice
    • Nakamura J, Tamura S, Kanda T, et al. Inhibition by topiramate of seizures in spontaneously epileptic rats and DBA/2 mice. Eur J Pharmacol 1994;254:83-9.
    • (1994) Eur J Pharmacol , vol.254 , pp. 83-89
    • Nakamura, J.1    Tamura, S.2    Kanda, T.3
  • 8
    • 0000337336 scopus 로고
    • Selective effects of topiramate on sustained repetitive firing and spontaneous bursting in cultured hippocampal neurons
    • Coulter DA, Sombati S, DeLorenzo RJ. Selective effects of topiramate on sustained repetitive firing and spontaneous bursting in cultured hippocampal neurons. Epilepsia 1993;34(suppl 2):123.
    • (1993) Epilepsia , vol.34 , Issue.2 SUPPL. , pp. 123
    • Coulter, D.A.1    Sombati, S.2    DeLorenzo, R.J.3
  • 9
    • 8244231508 scopus 로고    scopus 로고
    • Topiramate depresses intrinsic bursts in the rat subiculum in vitro
    • Kawasaki H, Lopantsev V, Zona C, Avoli M. Topiramate depresses intrinsic bursts in the rat subiculum in vitro. Epilepsia 1996;37(suppl 5):26.
    • (1996) Epilepsia , vol.37 , Issue.5 SUPPL. , pp. 26
    • Kawasaki, H.1    Lopantsev, V.2    Zona, C.3    Avoli, M.4
  • 10
    • 0030867764 scopus 로고    scopus 로고
    • Topiramate attenuates voltage-gated sodium currents in rat cerebellar granule cells
    • Zona C, Ciotti MT, Avoli M. Topiramate attenuates voltage-gated sodium currents in rat cerebellar granule cells. Neurosci Lett 1997; 231:123-6.
    • (1997) Neurosci Lett , vol.231 , pp. 123-126
    • Zona, C.1    Ciotti, M.T.2    Avoli, M.3
  • 11
    • 0002836373 scopus 로고
    • Topiramate effects on excitatory amino acid-mediated responses in cultured hippocampal neurons: Selective blockade of kainate currents
    • Coulter DA, Sombati S, DeLorenzo RJ. Topiramate effects on excitatory amino acid-mediated responses in cultured hippocampal neurons: selective blockade of kainate currents. Epilepsia 1995;36 (suppl 3):S40.
    • (1995) Epilepsia , vol.36 , Issue.3 SUPPL.
    • Coulter, D.A.1    Sombati, S.2    DeLorenzo, R.J.3
  • 12
    • 0030758984 scopus 로고    scopus 로고
    • Topiramate enhances GABA-mediated chloride flux and GABA-evoked chloride currents in murine brain neurons and increases seizure threshold
    • White HS, Brown SD, Woodhead JH, Skeen GA, Wolf HH. Topiramate enhances GABA-mediated chloride flux and GABA-evoked chloride currents in murine brain neurons and increases seizure threshold. Epilepsy Res 1997;28:167-79.
    • (1997) Epilepsy Res , vol.28 , pp. 167-179
    • White, H.S.1    Brown, S.D.2    Woodhead, J.H.3    Skeen, G.A.4    Wolf, H.H.5
  • 13
    • 0031754191 scopus 로고    scopus 로고
    • Topiramate increases cerebral GABA in healthy humans
    • Kuzniecky R, Hetherington H, Ho S, et al. Topiramate increases cerebral GABA in healthy humans. Neurology 1998;51:627-9.
    • (1998) Neurology , vol.51 , pp. 627-629
    • Kuzniecky, R.1    Hetherington, H.2    Ho, S.3
  • 14
    • 0033011122 scopus 로고    scopus 로고
    • Topiramate increases brain GABA, homocarnosine, and pyrrolidinone in patients with epilepsy
    • Petroff OAC, Hyder F, Mattson RH. Topiramate increases brain GABA, homocarnosine, and pyrrolidinone in patients with epilepsy. Neurology 1999;52:473-8.
    • (1999) Neurology , vol.52 , pp. 473-478
    • Petroff, O.A.C.1    Hyder, F.2    Mattson, R.H.3
  • 16
    • 0029922566 scopus 로고    scopus 로고
    • Topiramate placebo-controlled dose-ranging trial in refractory partial epilepsy using 200-, 400-, and 600-mg daily dosages
    • Faught E, Wilder BJ, Ramsay RE, et al. Topiramate placebo-controlled dose-ranging trial in refractory partial epilepsy using 200-, 400-, and 600-mg daily dosages. Neurology 1996;46:1684-90.
    • (1996) Neurology , vol.46 , pp. 1684-1690
    • Faught, E.1    Wilder, B.J.2    Ramsay, R.E.3
  • 17
    • 0029884747 scopus 로고    scopus 로고
    • Topiramate placebo-controlled dose-ranging trial in refractory partial epilepsy using 600-, 800-, and 1000-mg daily dosages
    • Privitera M, Fincham R, Penry J, et al. Topiramate placebo-controlled dose-ranging trial in refractory partial epilepsy using 600-, 800-, and 1000-mg daily dosages. Neurology 1996;46:1678-83.
    • (1996) Neurology , vol.46 , pp. 1678-1683
    • Privitera, M.1    Fincham, R.2    Penry, J.3
  • 18
    • 0016590785 scopus 로고
    • Epilepsy and γ-aminobutyric acid-mediated inhibition
    • Meldrum BS. Epilepsy and γ-aminobutyric acid-mediated inhibition. Int Rev Neurobiol 1975;17:1-36.
    • (1975) Int Rev Neurobiol , vol.17 , pp. 1-36
    • Meldrum, B.S.1
  • 19
    • 0019347565 scopus 로고
    • Transport and metabolism of glutamate and GABA in neurons and glial cells
    • Schousboe A. Transport and metabolism of glutamate and GABA in neurons and glial cells. Int Rev Neurobiol 1981;22:1-45.
    • (1981) Int Rev Neurobiol , vol.22 , pp. 1-45
    • Schousboe, A.1
  • 22
    • 0017553966 scopus 로고
    • γ-Vinyl GABA (4-amino-hex-5-enoic acid), a new selective irreversible inhibitor of GABA-T: Effects on brain GABA metabolism in mice
    • Jung MJ, Lippert B, Metcalf BW, Böhlen P, Schechter PJ. γ-Vinyl GABA (4-amino-hex-5-enoic acid), a new selective irreversible inhibitor of GABA-T: effects on brain GABA metabolism in mice. J Neurochem 1977;29:797-802.
    • (1977) J Neurochem , vol.29 , pp. 797-802
    • Jung, M.J.1    Lippert, B.2    Metcalf, B.W.3    Böhlen, P.4    Schechter, P.J.5
  • 23
    • 0031883542 scopus 로고    scopus 로고
    • A summary of mechanistic hypotheses of gabapentin pharmacology
    • Taylor CP, Gee NS, Su T-Z, et al. A summary of mechanistic hypotheses of gabapentin pharmacology. Epilepsy Res 1998;29: 233-49.
    • (1998) Epilepsy Res , vol.29 , pp. 233-249
    • Taylor, C.P.1    Gee, N.S.2    Su, T.-Z.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.