메뉴 건너뛰기




Volumn 6, Issue 2, 2005, Pages 65-77

Safety and efficacy of topical calcineurin inhibitors in the treatment of childhood atopic dermatitis

Author keywords

[No Author keywords available]

Indexed keywords

BETAMETHASONE VALERATE; CALCINEURIN INHIBITOR; CORTICOSTEROID; HYDROCORTISONE ACETATE; ITRACONAZOLE; LACTAM DERIVATIVE; MACROLACTAM; PIMECROLIMUS; TACROLIMUS; UNCLASSIFIED DRUG;

EID: 17244365003     PISSN: 11750561     EISSN: None     Source Type: Journal    
DOI: 10.2165/00128071-200506020-00001     Document Type: Review
Times cited : (92)

References (97)
  • 1
    • 0028929037 scopus 로고
    • Atopic dermatitis: The skin manifestation of atopy
    • Kapp A. Atopic dermatitis: the skin manifestation of atopy. Clin Exp Allergy 1995; 25: 210-9
    • (1995) Clin Exp Allergy , vol.25 , pp. 210-219
    • Kapp, A.1
  • 2
    • 0029871712 scopus 로고    scopus 로고
    • The occurrence of atopic dermatitis in North Europe: An international questionnaire study
    • Schultz Larsen F, Thomas T, Svensson A. The occurrence of atopic dermatitis in North Europe: an international questionnaire study. J Am Acad Dermatol 1996; 34: 760-4
    • (1996) J Am Acad Dermatol , vol.34 , pp. 760-764
    • Schultz Larsen, F.1    Thomas, T.2    Svensson, A.3
  • 3
    • 0026458409 scopus 로고
    • Is the prevalence of atopic dermatitis increasing?
    • Williams HC. Is the prevalence of atopic dermatitis increasing? Clin Exp Dermatol 1992; 17: 385-91
    • (1992) Clin Exp Dermatol , vol.17 , pp. 385-391
    • Williams, H.C.1
  • 5
    • 0037239101 scopus 로고    scopus 로고
    • Cost of illness of atopic dermatitis in children: A social perspective
    • Kemp AS. Cost of illness of atopic dermatitis in children: a social perspective. Pharmacoeconomics 2003; 21 (2): 105-13
    • (2003) Pharmacoeconomics , vol.21 , Issue.2 , pp. 105-113
    • Kemp, A.S.1
  • 6
    • 0035081867 scopus 로고    scopus 로고
    • What is the cost of atopic dermatitis in preschool children?
    • Emerson RM, Williams HC, Allen BR. What is the cost of atopic dermatitis in preschool children? Br J Dermatol 2001; 143: 514-22
    • (2001) Br J Dermatol , vol.143 , pp. 514-522
    • Emerson, R.M.1    Williams, H.C.2    Allen, B.R.3
  • 7
    • 2942576355 scopus 로고    scopus 로고
    • Late eczematous reactions to food in children with atopic dermatitis
    • Breuer K, Wulf A, Heratizadeh A, et al. Late eczematous reactions to food in children with atopic dermatitis. Clin Exp Allergy 2004; 34: 817-24
    • (2004) Clin Exp Allergy , vol.34 , pp. 817-824
    • Breuer, K.1    Wulf, A.2    Heratizadeh, A.3
  • 8
    • 0031830978 scopus 로고    scopus 로고
    • Environmental and other major provocation factors in atopic dermatitis
    • Werfel T, Kapp A. Environmental and other major provocation factors in atopic dermatitis. Allergy 1998; 53: 731-9
    • (1998) Allergy , vol.53 , pp. 731-739
    • Werfel, T.1    Kapp, A.2
  • 9
    • 0033044068 scopus 로고    scopus 로고
    • Evaluating the relevance of aeroallergen sensitization in atopic eczema with the atopy patch test: A randomized, double-blind multicenter study
    • Atopy Patch Test Study Group
    • Darsow U, Vieluf D, Ring J. Evaluating the relevance of aeroallergen sensitization in atopic eczema with the atopy patch test: a randomized, double-blind multicenter study. Atopy Patch Test Study Group. J Am Acad Dermatol 1999; 40: 187-93
    • (1999) J Am Acad Dermatol , vol.40 , pp. 187-193
    • Darsow, U.1    Vieluf, D.2    Ring, J.3
  • 10
    • 0022474944 scopus 로고
    • Challenge reactions in atopic dermatitis after percutaneous entry of mite allergen
    • Gondo A, Saeki NTY. Challenge reactions in atopic dermatitis after percutaneous entry of mite allergen. Br J Dermatol 1986; 115: 485-93
    • (1986) Br J Dermatol , vol.115 , pp. 485-493
    • Gondo, A.1    Saeki, N.T.Y.2
  • 11
    • 0032902616 scopus 로고    scopus 로고
    • Atopy patch test reactions are associated with T lymphocyte-mediated allergen-specific immune responses in atopic dermatitis
    • Wistokat-Wuelfing A, Schmidt P, Darsow U. et al. Atopy patch test reactions are associated with T lymphocyte-mediated allergen-specific immune responses in atopic dermatitis. Clin Exp Allergy 1999; 29: 513-21
    • (1999) Clin Exp Allergy , vol.29 , pp. 513-521
    • Wistokat-Wuelfing, A.1    Schmidt, P.2    Darsow, U.3
  • 12
    • 0027409867 scopus 로고
    • The involvement of eosinophils in the patch test reaction to aeroallergens in atopic dermatitis: Its relevance for the pathogenesis of atopic dermatitis
    • Bruijnzeel PL, Kuijper PH, Kapp A, et al. The involvement of eosinophils in the patch test reaction to aeroallergens in atopic dermatitis: its relevance for the pathogenesis of atopic dermatitis. Clin Exp Allergy 1993; 23: 97-109
    • (1993) Clin Exp Allergy , vol.23 , pp. 97-109
    • Bruijnzeel, P.L.1    Kuijper, P.H.2    Kapp, A.3
  • 13
    • 0025121175 scopus 로고
    • Immunohistochemical studies in mite-induced patch test site in atopic dermatitis
    • Tanaka Y, Anan S, Yoshida H. Immunohistochemical studies in mite-induced patch test site in atopic dermatitis. J Dermatol Sci 1990; 1: 361-8
    • (1990) J Dermatol Sci , vol.1 , pp. 361-368
    • Tanaka, Y.1    Anan, S.2    Yoshida, H.3
  • 14
    • 0026514978 scopus 로고
    • Human epidermal Langerhans cells express the high affinity receptor for immunoglobulin e (FcεRI)
    • Bieber T, de la Salle H, Wollenberg A, et al. Human epidermal Langerhans cells express the high affinity receptor for immunoglobulin E (FcεRI). J Exp Med 1992; 175: 1285-90
    • (1992) J Exp Med , vol.175 , pp. 1285-1290
    • Bieber, T.1    De La Salle, H.2    Wollenberg, A.3
  • 15
    • 0025098725 scopus 로고
    • Allergen presentation by epidermal Langerhans cells from patients with atopic dermatitis is mediated by IgE
    • Mudde GC, von Reijsen FC, Boland GJ, et al. Allergen presentation by epidermal Langerhans cells from patients with atopic dermatitis is mediated by IgE. Immunology 1990; 69: 335-41
    • (1990) Immunology , vol.69 , pp. 335-341
    • Mudde, G.C.1    Von Reijsen, F.C.2    Boland, G.J.3
  • 16
    • 0028176866 scopus 로고
    • Lesional expression of interferon-g in atopic eczema
    • Grewe M, Gyufko K, Schöpf E, et al. Lesional expression of interferon-g in atopic eczema. Lancet 1994; 343: 25-6
    • (1994) Lancet , vol.343 , pp. 25-26
    • Grewe, M.1    Gyufko, K.2    Schöpf, E.3
  • 17
    • 0029981818 scopus 로고    scopus 로고
    • Bi-phasic response against aeroallergen in atopic dermatitis showing a switch from initial TH2 response into a TH1 response in situ
    • Thepen T, Langeveld-Wiltschut EG, van Reijsen FC, et al. Bi-phasic response against aeroallergen in atopic dermatitis showing a switch from initial TH2 response into a TH1 response in situ. J Allergy Clin Immunol 1996; 97: 828-37
    • (1996) J Allergy Clin Immunol , vol.97 , pp. 828-837
    • Thepen, T.1    Langeveld-Wiltschut, E.G.2    Van Reijsen, F.C.3
  • 18
    • 0022642290 scopus 로고
    • Bacterial infection and atopic eczema
    • David TJ, Cambridge GC. Bacterial infection and atopic eczema. Arch Dis Child 1986; 81: 20-3
    • (1986) Arch Dis Child , vol.81 , pp. 20-23
    • David, T.J.1    Cambridge, G.C.2
  • 19
    • 0034748960 scopus 로고    scopus 로고
    • Bacterial infections and atopic dermatitis
    • Breuer K, Kapp A, Werfel T. Bacterial infections and atopic dermatitis. Allergy 2001; 56: 1034-41
    • (2001) Allergy , vol.56 , pp. 1034-1041
    • Breuer, K.1    Kapp, A.2    Werfel, T.3
  • 20
    • 0017888472 scopus 로고
    • Adverse effects from topical corticosteroids
    • Hill CJ, Rosenberg A. Adverse effects from topical corticosteroids. Cutis 1978; 21: 624-48
    • (1978) Cutis , vol.21 , pp. 624-648
    • Hill, C.J.1    Rosenberg, A.2
  • 21
    • 0020287253 scopus 로고
    • Systemic side-effects of topical preparation in children
    • Saurat JH. Systemic side-effects of topical preparation in children. Sem Hop 1982; 58: 1643-9
    • (1982) Sem Hop , vol.58 , pp. 1643-1649
    • Saurat, J.H.1
  • 22
    • 0016391335 scopus 로고
    • Adrenal unresponsiveness associated with clobetasol propionate
    • Feiwel M, Kelly WF. Adrenal unresponsiveness associated with clobetasol propionate. Lancet 1974; II: 112-3
    • (1974) Lancet , vol.2 , pp. 112-113
    • Feiwel, M.1    Kelly, W.F.2
  • 24
    • 0033987120 scopus 로고    scopus 로고
    • Ascomycins: Promising agents for the treatment of inflammatory skin diseases
    • Paul C, Graeber M, Stuetz A. Ascomycins: promising agents for the treatment of inflammatory skin diseases. Expert Opin Invest Drugs 2000; 9: 69-77
    • (2000) Expert Opin Invest Drugs , vol.9 , pp. 69-77
    • Paul, C.1    Graeber, M.2    Stuetz, A.3
  • 25
    • 0033698581 scopus 로고    scopus 로고
    • Manipulating immune responses with immunosuppressive agents that target NFAT
    • Kiani A, Rao A, Aramburu J. Manipulating immune responses with immunosuppressive agents that target NFAT. Immunity 2000; 12: 359-72
    • (2000) Immunity , vol.12 , pp. 359-372
    • Kiani, A.1    Rao, A.2    Aramburu, J.3
  • 26
    • 0032769627 scopus 로고    scopus 로고
    • A novel anti-inflammatory drug, SDZ ASM 981, for the treatment of skin diseases: In vitro pharmacology
    • Grassberger M, Baumruker T, Enz A, et al. A novel anti-inflammatory drug, SDZ ASM 981, for the treatment of skin diseases: in vitro pharmacology. Br J Dermatol 1999; 141: 264-73
    • (1999) Br J Dermatol , vol.141 , pp. 264-273
    • Grassberger, M.1    Baumruker, T.2    Enz, A.3
  • 27
    • 0025893168 scopus 로고
    • Calcineurin is a common target of cyclophilin-cyclosporine a and FKBP-FK506 complexes
    • Liu J, Farmer JD, Lane WS, et al. Calcineurin is a common target of cyclophilin-cyclosporine A and FKBP-FK506 complexes. Cell 1991; 66: 807-15
    • (1991) Cell , vol.66 , pp. 807-815
    • Liu, J.1    Farmer, J.D.2    Lane, W.S.3
  • 28
    • 0026575932 scopus 로고
    • The mechanism of action of cyclosporine A and FK506
    • Schreiber SL, Crabtree GR. The mechanism of action of cyclosporine A and FK506. Immunol Today 1992; 13: 136-42
    • (1992) Immunol Today , vol.13 , pp. 136-142
    • Schreiber, S.L.1    Crabtree, G.R.2
  • 29
    • 0028266839 scopus 로고
    • Regulation of interleukin-5 production by peripheral blood mononuclear cells from atopic patients with FK506, cyclosporine A and glucocorticoid
    • Mori A, Suko M, Nishizaki Y, et al. Regulation of interleukin-5 production by peripheral blood mononuclear cells from atopic patients with FK506, cyclosporine A and glucocorticoid. Int Arch Allergy Immunol 1994; 104 Suppl. 1: 32-5
    • (1994) Int Arch Allergy Immunol , vol.104 , Issue.1 SUPPL. , pp. 32-35
    • Mori, A.1    Suko, M.2    Nishizaki, Y.3
  • 30
    • 0026329354 scopus 로고
    • Characterization of the anti-inflammatory effect of FK506 on human mast cells
    • de Paulis A, Cirillo R, Ciccarelli A, et al. Characterization of the anti-inflammatory effect of FK506 on human mast cells. J Immunol 1991; 147: 4278-85
    • (1991) J Immunol , vol.147 , pp. 4278-4285
    • De Paulis, A.1    Cirillo, R.2    Ciccarelli, A.3
  • 31
    • 0026752175 scopus 로고
    • Anti-inflammatory effect of FK-506 on human skin mast cells
    • de Paulis A, Stellato C, Cirillo R, et al. Anti-inflammatory effect of FK-506 on human skin mast cells. J Invest Dermatol 1992; 99: 723-8
    • (1992) J Invest Dermatol , vol.99 , pp. 723-728
    • De Paulis, A.1    Stellato, C.2    Cirillo, R.3
  • 32
    • 0034909508 scopus 로고    scopus 로고
    • The ascomycin macrolactam pimecrolimus (Elidel, SDZ ASM 981) is a potent inhibitor of mediator release from human dermal mast cells and peripheral blood basophils
    • Zuberbier T, Chong SU, Grunow K, et al. The ascomycin macrolactam pimecrolimus (Elidel, SDZ ASM 981) is a potent inhibitor of mediator release from human dermal mast cells and peripheral blood basophils. J Allergy Clin Immunol 2001; 108: 275-80
    • (2001) J Allergy Clin Immunol , vol.108 , pp. 275-280
    • Zuberbier, T.1    Chong, S.U.2    Grunow, K.3
  • 33
    • 0035093545 scopus 로고    scopus 로고
    • Topical tacrolimus (FK506) leads to profound phenotypic and functional alterations of epidermal antigen-presenting dendritic cells in atopic dermatitis
    • Wollenberg A, Sharma S, von Bubnoff D, et al. Topical tacrolimus (FK506) leads to profound phenotypic and functional alterations of epidermal antigen-presenting dendritic cells in atopic dermatitis. J Allergy Clin Immunol 2001; 107: 519-25
    • (2001) J Allergy Clin Immunol , vol.107 , pp. 519-525
    • Wollenberg, A.1    Sharma, S.2    Von Bubnoff, D.3
  • 34
    • 0035116403 scopus 로고    scopus 로고
    • Human epidermal Langerhans' cells are targets for the immunosuppressive macrolide tacrolimus (FK506)
    • Panhans-Groß A, Novak N, Kraft S, et al. Human epidermal Langerhans' cells are targets for the immunosuppressive macrolide tacrolimus (FK506). J Allergy Clin Immunol 2001; 107: 345-52
    • (2001) J Allergy Clin Immunol , vol.107 , pp. 345-352
    • Panhans-Groß, A.1    Novak, N.2    Kraft, S.3
  • 35
    • 1842639441 scopus 로고    scopus 로고
    • Corticosteroids but not pimecrolimus affect viability, maturation and immune function of murine epidermal Langerhans cells
    • Hoetzenecker W, Meingassner JG, Ecker R, et al. Corticosteroids but not pimecrolimus affect viability, maturation and immune function of murine epidermal Langerhans cells. J Invest Dermatol 2004; 122 (3): 673-84
    • (2004) J Invest Dermatol , vol.122 , Issue.3 , pp. 673-684
    • Hoetzenecker, W.1    Meingassner, J.G.2    Ecker, R.3
  • 36
    • 0242550810 scopus 로고    scopus 로고
    • Pimecrolimus does not affect Langerhans cells in murine epidermis
    • Meingassner JG, Kowalski E, Schwendinger H, et al. Pimecrolimus does not affect Langerhans cells in murine epidermis. Br J Dermatol 2003; 149 (4): 853-7
    • (2003) Br J Dermatol , vol.149 , Issue.4 , pp. 853-857
    • Meingassner, J.G.1    Kowalski, E.2    Schwendinger, H.3
  • 37
    • 0023245677 scopus 로고
    • FK506 a novel immunosuppressant isolated from a Streptomyces I: Fermentation, isolation, and physico-chemical and biological characteristics
    • Tokyo
    • Kino T, Hatanaka H, Hashimoto M. FK506 a novel immunosuppressant isolated from a Streptomyces I: fermentation, isolation, and physico-chemical and biological characteristics. J Antibiot (Tokyo) 1987; 40: 1249-55
    • (1987) J Antibiot , vol.40 , pp. 1249-1255
    • Kino, T.1    Hatanaka, H.2    Hashimoto, M.3
  • 38
    • 0035096846 scopus 로고    scopus 로고
    • Staphylococcal colonization in atopic dermatitis treatment with topical tacrolimus (FK506)
    • Pournaras CC, Lübbe J, Saurat JH. Staphylococcal colonization in atopic dermatitis treatment with topical tacrolimus (FK506). J Invest Dermatol 2001; 116: 480-1
    • (2001) J Invest Dermatol , vol.116 , pp. 480-481
    • Pournaras, C.C.1    Lübbe, J.2    Saurat, J.H.3
  • 39
    • 0035144821 scopus 로고    scopus 로고
    • Tacrolimus ointment reduces the Staphylococcal colonization of atopic dermatitis lesions
    • Remitz A, Kyllönen H, Granlund H, et al. Tacrolimus ointment reduces the Staphylococcal colonization of atopic dermatitis lesions. J Allergy Clin Immunol 2001; 107: 196-7
    • (2001) J Allergy Clin Immunol , vol.107 , pp. 196-197
    • Remitz, A.1    Kyllönen, H.2    Granlund, H.3
  • 40
    • 0035116178 scopus 로고    scopus 로고
    • Tacrolimus (FK506): New treatment approach in superantigen-associated diseases like atopic dermatitis?
    • Hauk PJ, Leung DYM. Tacrolimus (FK506): new treatment approach in superantigen-associated diseases like atopic dermatitis? J Allergy Clin Immunol 2001; 107: 391-2
    • (2001) J Allergy Clin Immunol , vol.107 , pp. 391-392
    • Hauk, P.J.1    Leung, D.Y.M.2
  • 41
    • 0026648226 scopus 로고
    • Topical corticosteroids and Staphylococcus aureus in atopic dermatitis
    • Nilsson EJ, Henning CG, Magnusson J. Topical corticosteroids and Staphylococcus aureus in atopic dermatitis. J Am Acad Dermatol 1992; 27: 29-34
    • (1992) J Am Acad Dermatol , vol.27 , pp. 29-34
    • Nilsson, E.J.1    Henning, C.G.2    Magnusson, J.3
  • 42
    • 0035129118 scopus 로고    scopus 로고
    • Pyoderma gangraenosum: Successful topical therapy with tacrolimus (FK506)
    • Petering H, Kiehl P, Breuer K, et al. Pyoderma gangraenosum: successful topical therapy with tacrolimus (FK506). Hautarzt 2001; 52: 47-50
    • (2001) Hautarzt , vol.52 , pp. 47-50
    • Petering, H.1    Kiehl, P.2    Breuer, K.3
  • 43
    • 0034110810 scopus 로고    scopus 로고
    • SDZ ASM 981 is the first non-steroid that suppresses established nickel contact dermatitis elicited by allergen challenge
    • Queille-Roussel C, Graeber M, Thurston M, et al. SDZ ASM 981 is the first non-steroid that suppresses established nickel contact dermatitis elicited by allergen challenge. Contact Dermatitis 2000; 42: 349-50
    • (2000) Contact Dermatitis , vol.42 , pp. 349-350
    • Queille-Roussel, C.1    Graeber, M.2    Thurston, M.3
  • 44
    • 0036149321 scopus 로고    scopus 로고
    • Topical tacrolimus (FK506) and momethasone furoate in treatment of dyshidrotic palmar eczema: A randomized, observer-blinded trial
    • Schnopp C, Remling R, Möhrenschlager M, et al. Topical tacrolimus (FK506) and momethasone furoate in treatment of dyshidrotic palmar eczema: a randomized, observer-blinded trial. J Am Acad Dermatol 2002; 46: 73-7
    • (2002) J Am Acad Dermatol , vol.46 , pp. 73-77
    • Schnopp, C.1    Remling, R.2    Möhrenschlager, M.3
  • 45
    • 0036159587 scopus 로고    scopus 로고
    • Topical FK506 (tacrolimus) therapy for facial erythematous lesions of cutaneous lupus erythematosus
    • Yoshimasu T, Ohtani T, Sakamoto T, et al: Topical FK506 (tacrolimus) therapy for facial erythematous lesions of cutaneous lupus erythematosus. Eur J Dermatol 2002; 12: 50-2
    • (2002) Eur J Dermatol , vol.12 , pp. 50-52
    • Yoshimasu, T.1    Ohtani, T.2    Sakamoto, T.3
  • 46
    • 0032406844 scopus 로고    scopus 로고
    • The novel ascomycin derivate SDZ ASM 981 is effective for psoriasis when used topically under occlusion
    • Mrowietz U, Graeber M, Bräutigam M, et al. The novel ascomycin derivate SDZ ASM 981 is effective for psoriasis when used topically under occlusion. Br J Dermatol 1998; 139: 992-6
    • (1998) Br J Dermatol , vol.139 , pp. 992-996
    • Mrowietz, U.1    Graeber, M.2    Bräutigam, M.3
  • 47
    • 0036145480 scopus 로고    scopus 로고
    • Management of recalcitrant ulcerative oral lichen planus with topical tacrolimus
    • Kaliakatsou F, Hodgson TA, Lewsey JD, et al. Management of recalcitrant ulcerative oral lichen planus with topical tacrolimus. J Am Acad Dermatol 2002; 46: 35-41
    • (2002) J Am Acad Dermatol , vol.46 , pp. 35-41
    • Kaliakatsou, F.1    Hodgson, T.A.2    Lewsey, J.D.3
  • 48
    • 0036827765 scopus 로고    scopus 로고
    • Topical tacrolimus for repigmentation of vitiligo
    • Grimes PE, Soriano T, Dytoc MT. Topical tacrolimus for repigmentation of vitiligo. J Am Acad Dermatol 2002; 47: 789-91
    • (2002) J Am Acad Dermatol , vol.47 , pp. 789-791
    • Grimes, P.E.1    Soriano, T.2    Dytoc, M.T.3
  • 49
    • 0036063919 scopus 로고    scopus 로고
    • Cutaneous sarcoidosis successfully treated with topical tacrolimus
    • Katoh N, Mihara H, Yasuno H. Cutaneous sarcoidosis successfully treated with topical tacrolimus. Br J Dermatol 2002; 147: 154-6
    • (2002) Br J Dermatol , vol.147 , pp. 154-156
    • Katoh, N.1    Mihara, H.2    Yasuno, H.3
  • 50
    • 0034844209 scopus 로고    scopus 로고
    • Tacrolimus ointment in the treatment of chronic cutaneous graft-vs-host disease
    • Choi CJ, Nghiem P. Tacrolimus ointment in the treatment of chronic cutaneous graft-vs-host disease. Arch Dermatol 2001; 137: 1202-6
    • (2001) Arch Dermatol , vol.137 , pp. 1202-1206
    • Choi, C.J.1    Nghiem, P.2
  • 51
    • 3042848467 scopus 로고    scopus 로고
    • Topical pimecrolimus in the treatment of seborrheic dermatitis
    • Brownell I, Quan LT, Hsu S. Topical pimecrolimus in the treatment of seborrheic dermatitis. Dermatol Online J 2003; 9: 13
    • (2003) Dermatol Online J , vol.9 , pp. 13
    • Brownell, I.1    Quan, L.T.2    Hsu, S.3
  • 52
    • 0038723737 scopus 로고    scopus 로고
    • An open pilot study using tacrolimus ointment in the treatment of seborrheic dermatitis
    • Meshkinpour A, Sun J, Weinstein G. An open pilot study using tacrolimus ointment in the treatment of seborrheic dermatitis. J Am Acad Dermatol 2003; 49: 145-7
    • (2003) J Am Acad Dermatol , vol.49 , pp. 145-147
    • Meshkinpour, A.1    Sun, J.2    Weinstein, G.3
  • 53
    • 0035211722 scopus 로고    scopus 로고
    • Pimecrolimus (Elidel, SDZ ASM 981): Preclinical pharmacologic profile and skin selectivity
    • Stuetz A, Grassberger M, Meingassner JG. Pimecrolimus (Elidel, SDZ ASM 981): preclinical pharmacologic profile and skin selectivity. Semin Cutan Med Surg 2001; 20: 233-41
    • (2001) Semin Cutan Med Surg , vol.20 , pp. 233-241
    • Stuetz, A.1    Grassberger, M.2    Meingassner, J.G.3
  • 54
    • 0035034382 scopus 로고    scopus 로고
    • First experience of topical SDZ ASM 981 in children with atopic dermatitis
    • Harper J, Green A, Scott G, et al. First experience of topical SDZ ASM 981 in children with atopic dermatitis. Br J Dermatol 2001; 144: 781-7
    • (2001) Br J Dermatol , vol.144 , pp. 781-787
    • Harper, J.1    Green, A.2    Scott, G.3
  • 55
    • 0036169163 scopus 로고    scopus 로고
    • Low systemic exposure after repeated topical application of pimecrolimus (Elidel, SDZ ASM 981) in patients with atopic dermatitis
    • Van Leent EJM, Ebelin ME, Burtin PDB, et al. Low systemic exposure after repeated topical application of pimecrolimus (Elidel, SDZ ASM 981) in patients with atopic dermatitis. Dermatology 2002; 204: 63-8
    • (2002) Dermatology , vol.204 , pp. 63-68
    • Van Leent, E.J.M.1    Ebelin, M.E.2    Burtin, P.D.B.3
  • 56
    • 0036677154 scopus 로고    scopus 로고
    • Long-term management of atopic dermatitis in infants with topical pimecrolimus, a nonsteroid anti-inflammatory drug
    • Kapp A, Papp K, Bingham A, et al. Long-term management of atopic dermatitis in infants with topical pimecrolimus, a nonsteroid anti-inflammatory drug. J Allergy Clin Immunol 2002; 110: 277-84
    • (2002) J Allergy Clin Immunol , vol.110 , pp. 277-284
    • Kapp, A.1    Papp, K.2    Bingham, A.3
  • 57
    • 0036634394 scopus 로고    scopus 로고
    • Efficacy and safety of pimecrolimus cream in the long-term management of atopic dermatitis in children
    • Wahn U, Bos JD, Goodfield M, et al. Efficacy and safety of pimecrolimus cream in the long-term management of atopic dermatitis in children. Pediatrics 2002; 110: 1-8
    • (2002) Pediatrics , vol.110 , pp. 1-8
    • Wahn, U.1    Bos, J.D.2    Goodfield, M.3
  • 58
    • 19244366008 scopus 로고    scopus 로고
    • Pimecrolimus identifies a common genomic anti-inflammatory profile, is clinically highly effective in psoriasis and is well tolerated
    • Rappersberger K, Komar M, Ebelin ME, et al. Pimecrolimus identifies a common genomic anti-inflammatory profile, is clinically highly effective in psoriasis and is well tolerated. J Invest Dermatol 2002; 119: 876-87
    • (2002) J Invest Dermatol , vol.119 , pp. 876-887
    • Rappersberger, K.1    Komar, M.2    Ebelin, M.E.3
  • 59
    • 0031792219 scopus 로고    scopus 로고
    • A randomized, vehicle-controlled trial of tacrolimus ointment for treatment of atopic dermatitis in children
    • Boguniewicz M, Fiedler VC, Raimer S, et al. A randomized, vehicle-controlled trial of tacrolimus ointment for treatment of atopic dermatitis in children. J Allergy Clin Immunol 1998; 102: 637-44
    • (1998) J Allergy Clin Immunol , vol.102 , pp. 637-644
    • Boguniewicz, M.1    Fiedler, V.C.2    Raimer, S.3
  • 60
    • 0035164433 scopus 로고    scopus 로고
    • A 12-week study of tacrolimus ointment for the treatment of atopic dermatitis in pediatric patients
    • Paller A, Eichenfield LF, Leung DYM, et al. A 12-week study of tacrolimus ointment for the treatment of atopic dermatitis in pediatric patients. J Am Acad Dermatol 2001; 44: S47-57
    • (2001) J Am Acad Dermatol , vol.44
    • Paller, A.1    Eichenfield, L.F.2    Leung, D.Y.M.3
  • 61
    • 0036128526 scopus 로고    scopus 로고
    • Efficacy and safety of tacrolimus ointment compared with that of hydrocortisone acetate ointment in children with atopic dermatitis
    • Reitamo S, Van Leent EJM, Ho V, et al. Efficacy and safety of tacrolimus ointment compared with that of hydrocortisone acetate ointment in children with atopic dermatitis. J Allergy Clin Immunol 2002; 109: 539-46
    • (2002) J Allergy Clin Immunol , vol.109 , pp. 539-546
    • Reitamo, S.1    Van Leent, E.J.M.2    Ho, V.3
  • 62
    • 0035157535 scopus 로고    scopus 로고
    • Tacrolimus ointment for the treatment of atopic dermatitis in adult patients: Part I efficacy
    • Hanifin JM, Ling MR, Langley R, et al. Tacrolimus ointment for the treatment of atopic dermatitis in adult patients: part I efficacy. J Am Acad Dermatol 2001; 44 Suppl. 1: S28-38
    • (2001) J Am Acad Dermatol , vol.44 , Issue.1 SUPPL.
    • Hanifin, J.M.1    Ling, M.R.2    Langley, R.3
  • 63
    • 0242322394 scopus 로고    scopus 로고
    • A short-term trial of tacrolimus ointment for atopic dermatitis
    • European Tacrolimus Multicenter Atopic Dermatitis Study Group
    • Ruzicka T, Bieber T, Schoepf E, et al. A short-term trial of tacrolimus ointment for atopic dermatitis. European Tacrolimus Multicenter Atopic Dermatitis Study Group. N Engl J Med 1997; 337: 816-21
    • (1997) N Engl J Med , vol.337 , pp. 816-821
    • Ruzicka, T.1    Bieber, T.2    Schoepf, E.3
  • 64
    • 0036130451 scopus 로고    scopus 로고
    • Efficacy and safety of tacrolimus ointment compared with that of hydrocortisone butyrate ointment in adult patients with atopic dermatitis
    • Reitamo S, Rustin M, Ruzicka T, et al. Efficacy and safety of tacrolimus ointment compared with that of hydrocortisone butyrate ointment in adult patients with atopic dermatitis. J Allergy Clin Immunol 2002; 109: 547-55
    • (2002) J Allergy Clin Immunol , vol.109 , pp. 547-555
    • Reitamo, S.1    Rustin, M.2    Ruzicka, T.3
  • 65
    • 18544392044 scopus 로고    scopus 로고
    • Tacrolimus (FK506) ointment for atopic dermatitis: A phase I study in adults and children
    • Alaiti S, Kang S, Fiedler VC, et al. Tacrolimus (FK506) ointment for atopic dermatitis: a phase I study in adults and children. J Am Acad Dermatol 1998; 38: 69-76
    • (1998) J Am Acad Dermatol , vol.38 , pp. 69-76
    • Alaiti, S.1    Kang, S.2    Fiedler, V.C.3
  • 66
    • 0034123022 scopus 로고    scopus 로고
    • Tacrolimus: A further update of its pharmacology and therapeutic use in the management of organ transplantation
    • Plosker GL, Foster RH. Tacrolimus: a further update of its pharmacology and therapeutic use in the management of organ transplantation. Drugs 2000; 59: 323-89
    • (2000) Drugs , vol.59 , pp. 323-389
    • Plosker, G.L.1    Foster, R.H.2
  • 67
    • 0029849460 scopus 로고    scopus 로고
    • Relationship of FK506 whole blood concentration and efficacy and toxicity after liver and kidney transplantation
    • Kershner RP, Fitzsimmons WE. Relationship of FK506 whole blood concentration and efficacy and toxicity after liver and kidney transplantation. Transplantation 1996; 62: 920-5
    • (1996) Transplantation , vol.62 , pp. 920-925
    • Kershner, R.P.1    Fitzsimmons, W.E.2
  • 68
    • 0030904149 scopus 로고    scopus 로고
    • Initial experience with FK 506 in pediatric renal transplant recipients
    • McKee M, Segev D, Wise B. Initial experience with FK 506 in pediatric renal transplant recipients. J Pediatr Surg 1997; 32: 688-90
    • (1997) J Pediatr Surg , vol.32 , pp. 688-690
    • McKee, M.1    Segev, D.2    Wise, B.3
  • 69
    • 0034661894 scopus 로고    scopus 로고
    • The effect of immunosuppression on posttransplant lymphoproliferative disease in pediatric liver transplant patients
    • Younes BS, McDiarmid SV, Martin MG. The effect of immunosuppression on posttransplant lymphoproliferative disease in pediatric liver transplant patients. Transplantation 2000; 70: 94-9
    • (2000) Transplantation , vol.70 , pp. 94-99
    • Younes, B.S.1    McDiarmid, S.V.2    Martin, M.G.3
  • 70
    • 0034978116 scopus 로고    scopus 로고
    • Significant absorption of topical tacrolimus in 3 patients with Netherton syndrome
    • Allen A, Siegfried E, Silverman R, et al. Significant absorption of topical tacrolimus in 3 patients with Netherton syndrome. Arch Dermatol 2001; 137: 747-50
    • (2001) Arch Dermatol , vol.137 , pp. 747-750
    • Allen, A.1    Siegfried, E.2    Silverman, R.3
  • 71
    • 0032588114 scopus 로고    scopus 로고
    • Altered lamellar body secretion and stratum corneum membrane structure in Netherton syndrome
    • Fartasch M, Williams ML, Elias PM. Altered lamellar body secretion and stratum corneum membrane structure in Netherton syndrome. Arch Dermatol 1999; 135: 823-32
    • (1999) Arch Dermatol , vol.135 , pp. 823-832
    • Fartasch, M.1    Williams, M.L.2    Elias, P.M.3
  • 72
    • 0042635547 scopus 로고    scopus 로고
    • Topical treatment of Netherton's syndrome with tacrolimus ointment without significant systemic absorption
    • Boralevi F, Buzenet C, Taieb A. Topical treatment of Netherton's syndrome with tacrolimus ointment without significant systemic absorption. Br J Dermatol 2003; 149: 193-227
    • (2003) Br J Dermatol , vol.149 , pp. 193-227
    • Boralevi, F.1    Buzenet, C.2    Taieb, A.3
  • 73
    • 0028991403 scopus 로고
    • Successful treatment of resistant facial lesions of atopic dermatitis with 0.1% FK506 ointment
    • Aoyama H, Tabata N, Tanaka M, et al. Successful treatment of resistant facial lesions of atopic dermatitis with 0.1% FK506 ointment. Br J Dermatol 1995; 133: 492-500
    • (1995) Br J Dermatol , vol.133 , pp. 492-500
    • Aoyama, H.1    Tabata, N.2    Tanaka, M.3
  • 74
    • 2042444523 scopus 로고
    • Tacrolimus ointment for atopic dermatitis
    • Nakagawa H, Etoh T, Ishibashi Y, et al. Tacrolimus ointment for atopic dermatitis [letter]. Lancet 1994; 344 (8926): 883
    • (1994) Lancet , vol.344 , Issue.8926 , pp. 883
    • Nakagawa, H.1    Etoh, T.2    Ishibashi, Y.3
  • 75
    • 0035157388 scopus 로고    scopus 로고
    • Long-term safety and efficacy of tacrolimus ointment for the treatment of atopic dermatitis in children
    • Kang S, Lucky A, Pariser D, et al. Long-term safety and efficacy of tacrolimus ointment for the treatment of atopic dermatitis in children. J Am Acad Dermatol 2001; 44: S58-64
    • (2001) J Am Acad Dermatol , vol.44
    • Kang, S.1    Lucky, A.2    Pariser, D.3
  • 76
    • 0037222916 scopus 로고    scopus 로고
    • Treatment of atopic dermatitis and impact on quality of life: A review with emphasis on topical non-corticosteroids
    • Schiffner R, Schiffner-Rohe J, Landthaler M, et al. Treatment of atopic dermatitis and impact on quality of life: a review with emphasis on topical non-corticosteroids. Pharmacoeconomics 2003; 21 (3): 159-79
    • (2003) Pharmacoeconomics , vol.21 , Issue.3 , pp. 159-179
    • Schiffner, R.1    Schiffner-Rohe, J.2    Landthaler, M.3
  • 77
    • 0035153505 scopus 로고    scopus 로고
    • The impact of tacrolimus ointment on health-related quality of life in adults and pediatric patients with atopic dermatitis
    • Drake L, Prendergast M, Maher R, et al. The impact of tacrolimus ointment on health-related quality of life in adults and pediatric patients with atopic dermatitis. J Am Acad Dermatol 2001; 44: S65-72
    • (2001) J Am Acad Dermatol , vol.44
    • Drake, L.1    Prendergast, M.2    Maher, R.3
  • 78
    • 2642649496 scopus 로고    scopus 로고
    • Effectiveness of the ascomycin macrolactam SDZ ASM 981 in the topical treatment of atopic dermatitis
    • Van Leent EJM, Graeber M, Thurston M, et al. Effectiveness of the ascomycin macrolactam SDZ ASM 981 in the topical treatment of atopic dermatitis. Arch Dermatol 1998; 134: 805-9
    • (1998) Arch Dermatol , vol.134 , pp. 805-809
    • Van Leent, E.J.M.1    Graeber, M.2    Thurston, M.3
  • 79
    • 17744379151 scopus 로고    scopus 로고
    • SDZ ASM 981: An emerging safe and effective treatment for atopic dermatitis
    • Luger T, Van Leent EJM, Graeber M, et al. SDZ ASM 981: an emerging safe and effective treatment for atopic dermatitis. Br J Dermatol 2001; 144: 788-94
    • (2001) Br J Dermatol , vol.144 , pp. 788-794
    • Luger, T.1    Van Leent, E.J.M.2    Graeber, M.3
  • 80
    • 0036553479 scopus 로고    scopus 로고
    • Safety and efficacy of pimecrolimus (ASM 981) cream 1% in the treatment of mild and moderate atopic dermatitis in children and adolescents
    • Eichenfield LF, Lucky AW, Boguniewicz M, et al. Safety and efficacy of pimecrolimus (ASM 981) cream 1% in the treatment of mild and moderate atopic dermatitis in children and adolescents. J Am Acad Dermatol 2002; 138: 495-504
    • (2002) J Am Acad Dermatol , vol.138 , pp. 495-504
    • Eichenfield, L.F.1    Lucky, A.W.2    Boguniewicz, M.3
  • 81
    • 0037324145 scopus 로고    scopus 로고
    • Safety and efficacy of nonsteroid pimecrolimus cream 1% in the treatment of atopic dermatitis in infants
    • Ho V, Gupta A, Kaufmann R, et al. Safety and efficacy of nonsteroid pimecrolimus cream 1% in the treatment of atopic dermatitis in infants. J Pediatr 2003; 142: 155-62
    • (2003) J Pediatr , vol.142 , pp. 155-162
    • Ho, V.1    Gupta, A.2    Kaufmann, R.3
  • 82
    • 19044390564 scopus 로고    scopus 로고
    • Pimecrolimus cream in the long-term management of atopic dermatitis in adults: A six-month study
    • Meurer M, Folster-Holst R, Wozel G, et al. Pimecrolimus cream in the long-term management of atopic dermatitis in adults: a six-month study. Dermatology 2002; 205: 271-7
    • (2002) Dermatology , vol.205 , pp. 271-277
    • Meurer, M.1    Folster-Holst, R.2    Wozel, G.3
  • 83
    • 8344220598 scopus 로고    scopus 로고
    • Influence of pimecrolimus cream 1% on different morphological signs of eczema in infants with atopic dermatitis
    • Breuer K, Brautigam M, Kapp M, et al. Influence of pimecrolimus cream 1% on different morphological signs of eczema in infants with atopic dermatitis. Dermatology 2004; 209 (4): 314-20
    • (2004) Dermatology , vol.209 , Issue.4 , pp. 314-320
    • Breuer, K.1    Brautigam, M.2    Kapp, M.3
  • 84
    • 20844459817 scopus 로고    scopus 로고
    • A randomized investigator-blinded study comparing pimecrolimus cream 1% with tacrolimus ointment 0.03% in the treatment of pediatric patients with moderate atopic dermatitis
    • Kempers S, Boguniewicz M, Carter E, et al. A randomized investigator-blinded study comparing pimecrolimus cream 1% with tacrolimus ointment 0.03% in the treatment of pediatric patients with moderate atopic dermatitis. J Am Acad Dermatol 2004; 51 (4): 515-25
    • (2004) J Am Acad Dermatol , vol.51 , Issue.4 , pp. 515-525
    • Kempers, S.1    Boguniewicz, M.2    Carter, E.3
  • 85
    • 11144358531 scopus 로고    scopus 로고
    • 0.03% Tacrolimus ointment applied once or twice daily is more efficacious than 1% hydrocortisone acetate in children with moderate to severe atopic dermatitis: Results of a randomized double-blind controlled trial
    • Reitamo S, Harper J, Bos JD, et al. 0.03% Tacrolimus ointment applied once or twice daily is more efficacious than 1% hydrocortisone acetate in children with moderate to severe atopic dermatitis: results of a randomized double-blind controlled trial. Br J Dermatol 2004; 150 (3): 554-62
    • (2004) Br J Dermatol , vol.150 , Issue.3 , pp. 554-562
    • Reitamo, S.1    Harper, J.2    Bos, J.D.3
  • 86
    • 13444272116 scopus 로고    scopus 로고
    • Pimecrolimus for the treatment of atopic dermatitis
    • In press
    • Breuer K, Werfel T, Kapp A. Pimecrolimus for the treatment of atopic dermatitis. Therapy. In press
    • Therapy
    • Breuer, K.1    Werfel, T.2    Kapp, A.3
  • 87
    • 0033898753 scopus 로고    scopus 로고
    • Safety and efficacy of 1 year of tacrolimus ointment monotherapy in adults with atopic dermatitis
    • Reitamo S, Wollenberg A, Schoepf E, et al. Safety and efficacy of 1 year of tacrolimus ointment monotherapy in adults with atopic dermatitis. Arch Dermatol 2000; 136: 999-1006
    • (2000) Arch Dermatol , vol.136 , pp. 999-1006
    • Reitamo, S.1    Wollenberg, A.2    Schoepf, E.3
  • 89
    • 0036787041 scopus 로고    scopus 로고
    • Tacrolimus ointment for the treatment of atopic dermatitis is not associated with an increase in cutaneous infections
    • Fleischer AB, Ling M, Eichenfield L, et al. Tacrolimus ointment for the treatment of atopic dermatitis is not associated with an increase in cutaneous infections. J Am Acad Dermatol 2002; 47: 562-70
    • (2002) J Am Acad Dermatol , vol.47 , pp. 562-570
    • Fleischer, A.B.1    Ling, M.2    Eichenfield, L.3
  • 90
    • 0344687374 scopus 로고    scopus 로고
    • Teaching old drugs new tricks: Reincarnating immunosuppressants as antifungal drugs
    • Blankenship JR, Steinbach WJ, Perfect JR, et al. Teaching old drugs new tricks: reincarnating immunosuppressants as antifungal drugs. Curr Opin Invest Drugs 2003; 4: 192-9
    • (2003) Curr Opin Invest Drugs , vol.4 , pp. 192-199
    • Blankenship, J.R.1    Steinbach, W.J.2    Perfect, J.R.3
  • 92
    • 0013130764 scopus 로고    scopus 로고
    • Treatment with tacrolimus ointment is not associated with an increase in non-melanoma skin cancer
    • Rico MJ, Naylor M, Elmets CA, et al. Treatment with tacrolimus ointment is not associated with an increase in non-melanoma skin cancer [abstract]. J Eur Acad Dermatol Venerol 2003; 17 Suppl. 1: 53
    • (2003) J Eur Acad Dermatol Venerol , vol.17 , Issue.1 SUPPL. , pp. 53
    • Rico, M.J.1    Naylor, M.2    Elmets, C.A.3
  • 93
    • 0032435583 scopus 로고    scopus 로고
    • The molecular basis of glucocorti-coid-induced skin atrophy: Topical glucocorticoid apparently decreases both collagen synthesis and the corresponding collagen mRNA level in human skin in vitro
    • Oikarinen A, Haapasaari KM, Sutinen M, et al. The molecular basis of glucocorti-coid-induced skin atrophy: topical glucocorticoid apparently decreases both collagen synthesis and the corresponding collagen mRNA level in human skin in vitro. Br J Dermatol 1998; 139: 1106-10
    • (1998) Br J Dermatol , vol.139 , pp. 1106-1110
    • Oikarinen, A.1    Haapasaari, K.M.2    Sutinen, M.3
  • 94
    • 0002704768 scopus 로고    scopus 로고
    • Comparison of FK506 (tacrolimus) and glucocorticoid ointment on dermal hogeneity in rats
    • Hisatomi A, Mitamura T, Kimura M, et al. Comparison of FK506 (tacrolimus) and glucocorticoid ointment on dermal hogeneity in rats. J Toxicol Pathol 1997; 10: 97-102
    • (1997) J Toxicol Pathol , vol.10 , pp. 97-102
    • Hisatomi, A.1    Mitamura, T.2    Kimura, M.3
  • 95
    • 0031657805 scopus 로고    scopus 로고
    • Tacrolimus ointment does not affect collagen synthesis: Results of a single-center randomized trial
    • Reitamo S, Rissanen J, Remitz A, et al. Tacrolimus ointment does not affect collagen synthesis: results of a single-center randomized trial. J Invest Dermatol 1998; 111: 396-8
    • (1998) J Invest Dermatol , vol.111 , pp. 396-398
    • Reitamo, S.1    Rissanen, J.2    Remitz, A.3
  • 96
    • 0030827498 scopus 로고    scopus 로고
    • A novel anti-inflammatory drug, SDZ ASM 981, for the topical and oral treatment of skin diseases: In vivo pharmacology
    • Meingassner JG, Grassberger M, Fahrngruber H, et al. A novel anti-inflammatory drug, SDZ ASM 981, for the topical and oral treatment of skin diseases: in vivo pharmacology. Br J Dermatol 1997; 137: 568-76
    • (1997) Br J Dermatol , vol.137 , pp. 568-576
    • Meingassner, J.G.1    Grassberger, M.2    Fahrngruber, H.3
  • 97
    • 0035081866 scopus 로고    scopus 로고
    • The new topical ascomycin derivative SDZ ASM 981 does not induce skin atrophy when applied to normal skin for 4 weeks: A randomized, double-blind controlled study
    • Queille-Roussel C, Paul C, Duteil L, et al. The new topical ascomycin derivative SDZ ASM 981 does not induce skin atrophy when applied to normal skin for 4 weeks: a randomized, double-blind controlled study. Br J Dermatol 2001; 144: 507-13
    • (2001) Br J Dermatol , vol.144 , pp. 507-513
    • Queille-Roussel, C.1    Paul, C.2    Duteil, L.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.