SDZ ASM 981 is the first non-steroid that suppresses established nickel contact dermatitis elicited by allergen challenge

Contact Dermatitis

Volumn 42, Issue 6, 2000, Pages 349-350

  Queille Roussel, C ^c   Graeber, M ^a   Thurston, M ^a   Lachapelle, J M ^b   Decroix, J ^c   De Cuyper, C ^c   Ortonne, J P ^c  

^a NOVARTIS PHARMA AG   (Switzerland)

^b UNIVERSITÉ CATHOLIQUE DE LOUVAIN   (Belgium)

^c NONE

Author keywords

Established allergic contact dermatitis; Nickel; SDZ ASM 981; Treatment

Indexed keywords

ALLERGEN; BETAMETHASONE VALERATE; CYCLOSPORIN A; DRUG VEHICLE; LACTAM DERIVATIVE; NICKEL SULFATE; PIMECROLIMUS; PLACEBO;

ARTICLE; CLINICAL TRIAL; CONTACT DERMATITIS; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CREAM; DRUG EFFICACY; DRUG FORMULATION; DRUG TOLERABILITY; HUMAN; HUMAN EXPERIMENT; MULTICENTER STUDY; NORMAL HUMAN; PROVOCATION TEST; RANDOMIZED CONTROLLED TRIAL; SYMPTOM; TREATMENT OUTCOME;

ADMINISTRATION, TOPICAL; ALLERGENS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; DERMATITIS, ALLERGIC CONTACT; DERMATOLOGIC AGENTS; HUMANS; NICKEL; OINTMENTS; PATCH TESTS; SKIN; TACROLIMUS;

EID: 0034110810     PISSN: 01051873     EISSN: None     Source Type: Journal    
DOI: 10.1034/j.1600-0536.2000.042006349.x     Document Type: Article

References (6)

1. 1. Van Leent E J M, Graeber M, Thurston M et al. Effectiveness of the ascomycin macrolactam SDZ ASM 981 in the topical treatment of atopic dermatitis. Arch Dermatol 1998: 134: 805-809.
2. 2. Mrowietz U, Graeber M, Brautigam M et al. The novel ascomycin derivative SDZ ASM 981 is effective for psoriasis when used topically under occlusion. Br J Dermatol 1998: 139: 992-996.
3. 3. Meingassner JG, Grassberger M, Fahrngruber H et al. A novel anti-inflammatory drug, SDZ ASM 981, for the topical and oral treatment of skin diseases: in vivo pharmacology. Br J Dermatol 1997: 137: 568-576.
4. 4. Schemper M. A generalised Friedman test for data defined by intervals. Biom J 1984: 26: 305-308.
5. 5. Schemper M. A generalised Wilcoxon test for data defined by intervals. Commun Statist Theor Math A 13: no 6.
6. 6. Menno A, De Rie M A, Meinardi M M H M, Bos J D. Lack of efficacy of topical cyclosporin A in atopic dermatitis and allergic contact dermatitis. Acta Dermato-venereologica 1991: 77: 452-454.