Mechanistic data and cancer risk assessment: The need for quantitative molecular endpoints

Environmental and Molecular Mutagenesis

Volumn 45, Issue 2-3, 2005, Pages 214-221

  Preston, R Julian ^a  

^a U S ENVIRONMENTAL PROTECTION AGENCY   (United States)

Author keywords

Biomarkers; Cancer; Comparative genomic hybridization; Fluorescence in situ hybridization; Genomics; Proteomics; Real time PCR; Risk assessment

Indexed keywords

BIOLOGICAL MARKER; CARCINOGEN; COMPLEMENTARY DNA; MESSENGER RNA;

ANGIOGENESIS; BIOINFORMATICS; CANCER RISK; CARCINOGENESIS; COLORECTAL CANCER; COMPARATIVE GENOMIC HYBRIDIZATION; DNA HYBRIDIZATION; ENVIRONMENTAL EXPOSURE; FLUORESCENCE IN SITU HYBRIDIZATION; GENE AMPLIFICATION; GENE EXPRESSION; GENE MUTATION; GENETIC TRANSCRIPTION; HUMAN; METASTASIS; NONHUMAN; PROTEOMICS; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; REVIEW; RISK ASSESSMENT; RNA ISOLATION; RODENT; SERIAL ANALYSIS OF GENE EXPRESSION;

CARCINOGENICITY TESTS; CARCINOGENS, ENVIRONMENTAL; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDPOINT DETERMINATION; GENOMICS; HUMANS; MUTATION; NEOPLASMS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PROTEOMICS; RISK ASSESSMENT; TUMOR MARKERS, BIOLOGICAL; UNITED STATES; UNITED STATES ENVIRONMENTAL PROTECTION AGENCY;

ANIMALIA; RODENTIA;

EID: 17044393118     PISSN: 08936692     EISSN: None     Source Type: Journal    
DOI: 10.1002/em.20093     Document Type: Review

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