A Framework for Human Relevance Analysis of Information on Carcinogenic Modes of Action

Critical Reviews in Toxicology

Volumn 33, Issue 6, 2003, Pages 591-653

  Meek, M E ^a   Bucher, John R ^b   Cohen, Samuel M ^c   Dellarco, Vicki ^d   Hill, Richard N ^d   Lehman McKeeman, Lois D ^e   Longfellow, David G ^f   Pastoor, Timothy ^g   Seed, Jennifer ^d   Patton, Dorothy E ^h  

^a HEALTH CANADA   (Canada)

^b NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

^c UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

^d U S ENVIRONMENTAL PROTECTION AGENCY   (United States)

^e BRISTOL MYERS SQUIBB   (United States)

^f NATIONAL CANCER INSTITUTE   (United States)

^g SYNGENTA CROP PROTECTION   (United States)

^h ILSI Risk Science Institute   (United States)

Author keywords

Acrylonitrile; Atrazine; Carcinogenic mode of action; Chloroform; d limonene; Ethylene oxide; Human relevance of animal carcinogens; Melamine; Phenobarbital; Risk assessment

Indexed keywords

2 OXIRANECARBONITRILE; 8 HYDROXYDEOXYGUANOSINE; ACRYLONITRILE; ALKYLATING AGENT; ALPHA 2 MACROGLOBULIN; ATRAZINE; CARCINOGEN; CHLOROFORM; ETHYLENE OXIDE; ETHYLENE OXIDE DERIVATIVE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LIMONENE; LUTEINIZING HORMONE; MELAMINE; PHENOBARBITAL; THYROTROPIN; TUMOR PROTEIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; BRAIN TUMOR; CANCER RISK; CARCINOGENICITY; CELL PROLIFERATION; CHEMOTAXONOMY; CONTROLLED STUDY; CYTOTOXICITY; DATA ANALYSIS; DRUG CARCINOGENICITY; DRUG CLEARANCE; DRUG MECHANISM; EVALUATION; EXPERIMENTAL ANIMAL; FEMALE; HORMONAL REGULATION; HUMAN; HUMAN RELEVANCE ANALYSIS; KIDNEY TUMOR; LABORATORY DIAGNOSIS; MALE; MOUSE; NONHUMAN; ORGANIZATION; OUTCOMES RESEARCH; PREDICTION; PROCESS DESIGN; PROTEIN ANALYSIS; QUALITATIVE ANALYSIS; QUANTITATIVE ANALYSIS; RAT; RELIABILITY; REVIEW; RISK ASSESSMENT; RISK FACTOR; SPECIES COMPARISON; STATISTICAL ANALYSIS; TISSUE SPECIFICITY; TOXICOKINETICS; UNITED STATES; UROLITHIASIS;

ANIMALIA;

EID: 9144238300     PISSN: 10408444     EISSN: None     Source Type: Journal    
DOI: 10.1080/713608373     Document Type: Review

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