15-Amido erythromycins: Synthesis and in Vitro activity of a new class of macrolide antibiotics

Journal of Antibiotics

Volumn 58, Issue 3, 2005, Pages 167-177

  Shaw, Simon J ^a   Abbanat, Darren ^b   Ashley, Gary W ^a   Bush, Karen ^b   Foleno, Barbara ^b   Macielag, Mark ^b   Zhang, Dan ^a   Myles, David C ^a  

^a KOSAN BIOSCIENCES INC   (United States)

^b JOHNSON AND JOHNSON PHARMACEUTICAL RESEARCH AND DEVELOPMENT   (United States)

Author keywords

Antibacterial; Chemobiosynthesis; Diketide; Erythromycin

Indexed keywords

15 (3 INDOLYLACETAMIDO)ERYTHROMYCIN A; 15 (3 QUINOLYLCARBOXAMIDO)ERYTHROMYCIN A; 15 (4 QUINOLYLCARBOXAMIDO)ERYTHROMYCIN A; 15 (4'' CHLOROBIPHENYLACETAMIDO)ERYTHROMYCIN A; 15 (5 INDOLYLCARBOXAMIDO)ERYTHROMYCIN A; 15 (6 QUINOLYLCARBOXAMIDO)ERYTHROMYCIN A; 15 (BENZYLOXYACETAMIDO)ERYTHROMYCIN A; 15 (PHENYLACETAMIDO)ERYTHROMYCIN A; 15 (PHENYLPENTANAMIDO)ERYTHROMYCIN A; 15 (PHENYLPROPANAMIDO)ERYTHROMYCIN A; 15 AZIDO 2' ACETYLERYTHROMYCIN A; 15 [2 (2 FURANYL)PHENYLACETAMIDO]ERYTHROMYCIN A; 15 [3 (2 FURANYL)PHENYLACETAMIDO]ERYTHROMYCIN A; 15 [3 (3 FURANYL)PHENYLACETAMIDO]ERYTHROMYCIN A; 15 [3 (3 FURANYL)PHENYLPROPANAMIDO]ERYTHROMYCIN A; 15 [3 (3 PYRROLYL)PHENYLACETAMIDO]ERYTHROMYCIN A; 15 [3 (3 THIENYL)PHENYLACETAMIDO]ERYTHROMYCIN A; 15 [4 (2 FURANYL)PHENYLACETAMIDO]ERYTHROMYCIN A; 15 [4 (2 PHENYL 5 METHYLOXAZOLYL)ACETAMIDO]ERYTHROMYCIN A; AMIDE; ERYTHROMYCIN; ERYTHROMYCIN DERIVATIVE; MACROLIDE; UNCLASSIFIED DRUG;

ANTIBACTERIAL ACTIVITY; ARTICLE; DRUG STRUCTURE; DRUG SYNTHESIS; IN VITRO STUDY; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PRIORITY JOURNAL;

EID: 17044368876     PISSN: 00218820     EISSN: None     Source Type: Journal    
DOI: 10.1038/ja.2005.19     Document Type: Article

References (14)

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