Saccharopolyspora erythraea-catalyzed bioconversion of 6-deoxyerythronolide B analogs for production of novel erythromycins

Journal of Biotechnology

Volumn 92, Issue 3, 2002, Pages 217-228

  Carreras, Christopher ^a   Frykman, Scott ^a   Ou, Sally ^a   Cadapan, Lawrence ^a   Zavala, Stefan ^a   Woo, Elaine ^a   Leaf, Timothy ^a   Carney, John ^a   Burlingame, Mark ^a   Patel, Sajel ^a   Ashley, Gary ^a   Licari, Peter ^a  

^a KOSAN BIOSCIENCES INC   (United States)

Author keywords

Bioconversion; Erythromycin; Polyketide synthase; S. erythraea

Indexed keywords

CONDENSATION; GENETIC ENGINEERING; HYDROXYLATION; MUTAGENS; PH; THERMAL EFFECTS;

ERYTHROMYCIN ANALOGS;

BIOCONVERSION;

6 DEOXYERYTHRONOLIDE B DERIVATIVE; ERYTHROMYCIN B DERIVATIVE; ERYTHROMYCIN C DERIVATIVE; ERYTHROMYCIN D DERIVATIVE; ERYTHROMYCIN DERIVATIVE; ERYTHRONOLIDE DERIVATIVE; OXYGEN; POLYKETIDE; POLYKETIDE SYNTHASE; PROPIONIC ACID; UNCLASSIFIED DRUG;

ARTICLE; BACTERIUM MUTANT; BIOTRANSFORMATION; CATALYSIS; CONTROLLED STUDY; DRUG STRUCTURE; DRUG SYNTHESIS; GENETIC MANIPULATION; GLYCOSYLATION; HYDROXYLATION; METHYLATION; NONHUMAN; PH; PLASMID; POLYMERIZATION; PRECURSOR; PRIORITY JOURNAL; SACCHAROPOLYSPORA; STREPTOMYCES ERYTHRAEUS; TEMPERATURE;

BIOREACTORS; BIOTECHNOLOGY; BIOTRANSFORMATION; CULTURE MEDIA; ERYTHROMYCIN; KINETICS; MOLECULAR STRUCTURE; MULTIENZYME COMPLEXES; MUTATION; PLASMIDS; SACCHAROPOLYSPORA; STREPTOMYCES;

SACCHAROPOLYSPORA ERYTHRAEA; STREPTOMYCES COELICOLOR;

EID: 0037126850     PISSN: 01681656     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0168-1656(01)00372-8     Document Type: Article

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