Generation of a conditionally null allele of hnf4α

Genesis

Volumn 32, Issue 2, 2002, Pages 130-133

  Parviz, Fereshteh ^a   Li, Jixuan ^a   Kaestner, Klaus H ^b   Duncan, Stephen A ^a  

^a MEDICAL COLLEGE OF WISCONSIN   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CRE RECOMBINASE; DIPHTHERIA TOXIN; GANCICLOVIR; HEPATOCYTE NUCLEAR FACTOR 4;

ALLELE; ARTICLE; CHIMERA; DNA BINDING; DNA PROBE; EMBRYO DEVELOPMENT; GENE EXPRESSION; GENE LOCUS; GENETIC RECOMBINATION; GERM LINE; IMMUNOHISTOCHEMISTRY; INTRON; LIVER DEVELOPMENT; MORPHOGENESIS; MORULA; NULL ALLELE; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TETRAPLOIDY;

ANIMALS; DNA-BINDING PROTEINS; FEMALE; GENE EXPRESSION REGULATION; HEPATOCYTE NUCLEAR FACTOR 4; INTEGRASES; MALE; MICE; MICE, TRANSGENIC; PHOSPHOPROTEINS; SEQUENCE DELETION; TRANSCRIPTION FACTORS; VIRAL PROTEINS;

EID: 0036196060     PISSN: 1526954X     EISSN: None     Source Type: Journal    
DOI: 10.1002/gene.10058     Document Type: Article

References (8)

1. Disruption of the HNF-4 gene, expressed in visceral endoderm, leads to cell death in embryonic ectoderm and impaired gastrulation of mouse embryos
2. Murine gastrulation requires HNF-4 regulated gene expression in the visceral endoderm: Tetraploid rescue of HNF-4-/- embryos
3. Functional domains of the nuclear receptor hepatocyte nuclear factor 4
4. Mammalian hepatocyte differentiation requires the transcription factor HNF-4alpha
5. Derivation of completely cell culture-derived mice from early passage embryonic stem cells
6. Liver-enriched transcription factor HNF-4 is a novel member of the steroid hormone receptor superfamily
7. Hepatocyte nuclear factor 3beta (Foxa2) is dispensable for maintaining the differentiated state of the adult hepatocyte
8. Non-injection methods for the production of embryonic stem cellembryo chimaeras