The goal of intragraft gene therapy

Contributions to Nephrology

Volumn 146, Issue , 2005, Pages 143-150

  Tomasoni, Susanna ^a   Benigni, Ariela ^a  

^a MARIO NEGRI INSTITUTE FOR PHARMACOLOGICAL RESEARCH   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ALLOTRANSPLANTATION; ANIMAL; COMPARATIVE STUDY; DISEASE MODEL; FEMALE; GENE THERAPY; GENE TRANSFER; GRAFT REJECTION; GRAFT SURVIVAL; HUMAN; IMMUNOSUPPRESSIVE TREATMENT; MALE; METHODOLOGY; MOUSE; ORGAN TRANSPLANTATION; RAT; REVIEW; RISK ASSESSMENT; SENSITIVITY AND SPECIFICITY; TREATMENT OUTCOME;

ANIMALS; DISEASE MODELS, ANIMAL; FEMALE; GENE THERAPY; GENE TRANSFER TECHNIQUES; GRAFT REJECTION; GRAFT SURVIVAL; HUMANS; MALE; MICE; ORGAN TRANSPLANTATION; RATS; RISK ASSESSMENT; SENSITIVITY AND SPECIFICITY; TRANSPLANTATION CONDITIONING; TRANSPLANTATION, HOMOLOGOUS; TREATMENT OUTCOME;

EID: 16544376027     PISSN: 03025144     EISSN: None     Source Type: Book Series    
DOI: None     Document Type: Article

References (25)

1. Perico N, Remuzzi G: Prevention of transplant rejection. Current treatment guidelines and future developments. Drugs 1997;54:533-570.
2. Tomasoni S, Azzollini N, Casiraghi F, Capogrossi MC, Remuzzi G, Benigni A: CTLA4Ig gene transfer prolongs survival and induces donor-specific tolerance in a rat renal allograft. J Am Soc Nephrol 2000;11:747-752.
3. Olthoff KM, Judge TA, Gelman AE, Da Shen X, Hancock WW, Turka LA, Shaked A: Adenovirus-mediated gene transfer into cold-preserved liver allografts: Survival pattern and unresponsiveness following transduction with CTLA4Ig. Nat Med 1998;4:194-200.
4. Yang Z, Rostami S, Koeberlein B, Barker CF, Naji A: Cardiac allograft tolerance induced by intra-arterial infusion of recombinant adenoviral CTLA4Ig. Transplantation 1999;67:1517-1523.
5. Guillot C, Mathieu P, Coathalem H, Gerdes CA, Menoret S, Braudeau C, Tesson L, Renaudin K, Castro MG, Lowenstein PR, Anegon I: Tolerance to cardiac allografts via local and systemic mechanisms after adenovirus-mediated CTLA4Ig expression. J Immunol 2000;164:5258-5268.
6. Chang GJ, Liu T, Feng S, Bedolli M, O'rourke RW, Schmidt G, Roberts JP, Stock PG: Targeted gene therapy with CD40Ig to induce long-term acceptance of liver allografts. Surgery 2002;132:149-156.
7. Guillot C, Guillonneau C, Mathieu P, Gerdes CA, Menoret S, Braudeau C, Tesson L, Renaudin K, Castro MG, Lowenstein PR, Anegon I: Prolonged blockade of CD40-CD40 ligand interactions by gene transfer of CD40Ig results in long-term heart allograft survival and donor-specific hyporesponsiveness, but does not prevent chronic rejection. J Immunol 2002;168:1600-1609.
8. Kanaya K, Tsuchida Y, Inobe M, Murakami M, Hirose T, Kon S, Kawaguchi S, Wada T, Yamashita T, Ishii S, Uede T: Combined gene therapy with adenovirus vectors containing CTLA4Ig and CD40Ig prolongs survival of composite tissue allografts in rat model. Transplantation 2003;75:275-281.
9. Yamashita K, Masunaga T, Yanagida N, Takehara M, Hashimoto T, Kobayashi T, Echizenya H, Hua N, Fujita M, Murakami M, Furukawa H, Uede T, Todo S: Long-term acceptance of rat cardiac allografts on the basis of adenovirus mediated CD40Ig plus CTLA4Ig gene therapies. Transplantation 2003;76:1089-1096.
10. Swenson KM, Ke B, Wang T, Markowitz JS, Maggard MA, Spear GS, Imagawa DK, Goss JA, Busuttil RW, Seu P: Fas ligand gene transfer to renal allografts in rats. Transplantation 1998;65:155-160.
11. Ke B, Coito AJ, Kato H, Zhai Y, Wang T, Sawatzki B, Seu P, Busuttil RW, Kupiec-Weglinski JW: Fas ligand gene transfer prolongs rat renal allograft survival and down-regulates anti-apoptotic bag-1 in parallel with enhanced Th2-type cytokine expression. Transplantation 2000;69:1690-1694.
12. Qin L, Chavin KD, Ding Y, Tahara H, Favaro JP, Woodward JE, Suzuki T, Robbins PD, Lotze MT, Bromberg JS: Retrovirus-mediated transfer of viral IL-10 gene prolongs murine cardiac allograft survival. J Immunol 1996;156:2316-2323.
13. Zuo Z, Wang C, Carpenter D, Okada Y, Nicolaidou E, Yoyoda M, Trento A, Jordan SC: Prolongation of allograft survival with viral IL-10 transfection in a highly histoincompatible model of rat heart allograft rejection. Transplantation 2001;71:686-691.
14. DeBruyne LA, Li K, Chan SY, Qin L, Bishop DK, Bromberg JS: Lipid-mediated gene transfer of viral IL-10 prolongs vascularized cardiac allograft survival by inhibiting donor-specific cellular and humoral immune responses. Gene Ther 1998;5:1079-1087.
15. Adachi O, Yamato E, Kawamoto S, Yamamoto M, Tahara H, Tabayashi K, Miyazaki J-I: High-level expression of viral interleukin-10 in cardiac allografts fails to prolong graft survival. Transplantation 2002;74:1603-1608.
16. Tomasoni S, Longaretti L, Azzollini N, Gagliardini E, Mister M, Buehler T, Remuzzi G, Benigni A: Favorable effect of cotransfection with TGF-beta and CTLA4Ig of the donor kidney on allograft survival. Am J Nephrol 2004;24:275-283.
17. Shinozaki K, Yahata H, Tanji H, Sakaguchi T, Ito H, Dohi K: Allograft transduction of IL-10 prolongs survival following orthotopic liver transplantation. Gene Ther 1999;6:816-822.
18. Ke B, Shen XD, Zhai Y, Gao F, Busuttil RW, Volk H-D, Kupiec-Weglinski JW: Heme oxygenase 1 mediates the immunomodulatory and antiapoptotic effects of interleukin 13 gene therapy in vivo and in vitro. Hum Gene Ther 2002;13:1845-1857.
19. Qin L, Chavin KD, Ding Y, Favaro JP, Woodward JE, Lin J, Tahara H, Robbins PD, Shaked A, Ho DY, Sapolsky RM, Lotze MT, Bromberg JS: Multiple vectors effectively achieve gene transfer in a murine cardiac transplantation model. Transplantation 1995;59:809-816.
20. Chan SY, Goodman RE, Szmuszkovicz JR, Roessler B, Eichwald EJ, Bishop K: DNA-liposome versus adenoviral mediated gene transfer of transforming growth factor beta-1 in vascularized cardiac allografts: Differential sensitivity of CD4+ and CD8+ T cells to transforming growth factor beta-1. Transplantation 2000;70:1292-1301.
21. Yang J, Reutzel-Selke A, Steier C, Jurisch A, Tullius SG, Sawitzki B, Kolls J, Volk H-D, Ritter T: Targeting of macrophage activity by adenovirus-mediated intragraft overexpression of TNFRp55-Ig, IL-12p40, and vIL-10 ameliorates adenovirus-mediated chronic graft injury, whereas stimulation of macrophages by overexpression of IFN-g accelerates chronic graft injury in a rat renal allograft model. J Am Soc Nephrol 2003;14:214-225.
22. Lehmann TG, Wheeler MD, Schoonhoven R, Bunzendahl H, Samulski RJ, Thurman RG: Delivery of Cu/Zn-superoxide dismutase genes with a viral vector minimizes liver injury and improves survival after liver transplantation in the rat. Transplantation 2000;69:1051-1057.
23. Coito AJ, Buelow R, Shen XD, Amersi F, Moore C, Volk H-D, Busuttil RW, Kupiec-Weglinski JW: Heme oxygenase-1 gene transfer inhibits inducible nitric oxide synthase expression and protects genetically fat Zucker rat livers from ischemia-reperfusion injury. Transplantation 2002;74:96-102.
24. Ke B, Buelow R, Shen XD, Melinek J, Amersi F, Gao F, Ritter T, Volk H-D, Busuttil RW, Kupiec-Weglinski JW: Heme oxygenase 1 gene transfer prevents CD95/Fas ligand-mediated apoptosis and improves liver allograft survival via carbon monoxide signaling pathway. Hum Gene Ther 2002;13:1189-1199.
25. Braudeau C, Bouchet D, Tesson L, Iyer S, Rémy S, Buelow R, Anegon I, Chauveau C: Induction of long-term cardiac allograft survival by heme oxygenase-1 gene transfer. Gene Ther 2004;11:701-710.