메뉴 건너뛰기




Volumn 5, Issue 8, 1998, Pages 1079-1087

Lipid-mediated gene transfer of viral IL-10 prolongs vascularized cardiac allograft survival by inhibiting donor-specific cellular and humoral immune responses

Author keywords

Gene transfer; Immunotherapy; Transplantation; Viral interleukin 10 (vIL 10)

Indexed keywords

CATION; COLLAGEN; CYTOKINE; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M; INTERLEUKIN 10; LIPID; MONOCLONAL ANTIBODY;

EID: 0031667550     PISSN: 09697128     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.gt.3300694     Document Type: Article
Times cited : (75)

References (51)
  • 1
    • 0028963532 scopus 로고
    • Multiple vectors effectively achieve gene transfer in a murine cardiac transplantation model: Immunosuppression with TGF-βl or vIL-10
    • Qin L et al. Multiple vectors effectively achieve gene transfer in a murine cardiac transplantation model: immunosuppression with TGF-βl or vIL-10. Transplantation 1995; 59: 809-816.
    • (1995) Transplantation , vol.59 , pp. 809-816
    • Qin, L.1
  • 2
    • 13344249764 scopus 로고    scopus 로고
    • Retrovirus-mediated transfer of viral IL-10 gene prolongs murine cardiac ailograft survival
    • Qin L et al. Retrovirus-mediated transfer of viral IL-10 gene prolongs murine cardiac ailograft survival. J Immunol 1996; 156: 2316-2323.
    • (1996) J Immunol , vol.156 , pp. 2316-2323
    • Qin, L.1
  • 3
    • 0031865741 scopus 로고    scopus 로고
    • Interactions between the immune system and gene therapy vectors. Bidirectional regulation of response and expression
    • Bromberg JS, DeBruyne LA, Qin L. Interactions between the immune system and gene therapy vectors. Bidirectional regulation of response and expression. Adv Immunol 1998; 69: 353-408.
    • (1998) Adv Immunol , vol.69 , pp. 353-408
    • Bromberg, J.S.1    DeBruyne, L.A.2    Qin, L.3
  • 5
    • 0025335354 scopus 로고
    • Homology of cytokine synthesis inhibitory factor (IL-10) to the Epstein-Barr virus gene BCRFI
    • Moore KW et al. Homology of cytokine synthesis inhibitory factor (IL-10) to the Epstein-Barr virus gene BCRFI. Science 1990; 248: 1230-1234.
    • (1990) Science , vol.248 , pp. 1230-1234
    • Moore, K.W.1
  • 6
    • 0027513170 scopus 로고
    • Interleukin-10
    • Moore KW et al. Interleukin-10. Annu Rev Immunol 1993; 11: 165-190.
    • (1993) Annu Rev Immunol , vol.11 , pp. 165-190
    • Moore, K.W.1
  • 7
    • 0025733855 scopus 로고
    • The role of IL-10 in crossregulation of TH1 and TH2 responses
    • Mosmann TR, Moore KW. The role of IL-10 in crossregulation of TH1 and TH2 responses. Immunol Today 1991; 12: A49-53.
    • (1991) Immunol Today , vol.12
    • Mosmann, T.R.1    Moore, K.W.2
  • 8
    • 0027177008 scopus 로고
    • IL-12: Initiation cytokine for cell-mediated immunity
    • Scott P. IL-12: initiation cytokine for cell-mediated immunity. Science 1993; 260: 496-497.
    • (1993) Science , vol.260 , pp. 496-497
    • Scott, P.1
  • 9
    • 0027491655 scopus 로고
    • Interleukin 12 acts directly on CD4- T cells to enhance priming for interferon γ production and diminishes interleukin 4 inhibition of such priming
    • Seder RA, Gazzinelli R, Sher A, Paul WE. Interleukin 12 acts directly on CD4- T cells to enhance priming for interferon γ production and diminishes interleukin 4 inhibition of such priming. Proc Natl Acad Sci USA 1993; 90: 10188-10192.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 10188-10192
    • Seder, R.A.1    Gazzinelli, R.2    Sher, A.3    Paul, W.E.4
  • 10
    • 0026094306 scopus 로고
    • Interleukin 10 (IL-10) inhibits cytokine synthesis by human monocytes: An autoregulatory role of IL-10 produced by monocytes
    • de Waal Malefyt R et al. Interleukin 10 (IL-10) inhibits cytokine synthesis by human monocytes: an autoregulatory role of IL-10 produced by monocytes. J Exp Med 1991; 174: 1209-1220.
    • (1991) J Exp Med , vol.174 , pp. 1209-1220
    • Waal Malefyt, R.1
  • 11
    • 0025889028 scopus 로고
    • 1991. IL-10 inhibits cytokine production by activated macrophages
    • Fiorentino DF et al. 1991. IL-10 inhibits cytokine production by activated macrophages. J Immunol 1991; 147: 3815-3822.
    • (1991) J Immunol , vol.147 , pp. 3815-3822
    • Fiorentino, D.F.1
  • 12
    • 0026000892 scopus 로고
    • Interleukin 10 (IL-10) and viral IL-10 strongly reduce antigen-specific human T cell proliferation by diminishing the antigen-presenting capacity of monocytes via down-regulation of class II major histocompatibility complex expression
    • de Waal Malefyt R et al. Interleukin 10 (IL-10) and viral IL-10 strongly reduce antigen-specific human T cell proliferation by diminishing the antigen-presenting capacity of monocytes via down-regulation of class II major histocompatibility complex expression. J Exp Med 1991; 174: 915-924.
    • (1991) J Exp Med , vol.174 , pp. 915-924
    • De Waal Malefyt, R.1
  • 13
    • 0027320133 scopus 로고
    • Inhibition of Langerhans cell antigen-presenting function by IL-10. A role for IL-10 in induction of tolerance
    • Enk AH, Angeloni VL, Udey MC, Katz SI. Inhibition of Langerhans cell antigen-presenting function by IL-10. A role for IL-10 in induction of tolerance. J Immunol 1993; 151: 2390-2398.
    • (1993) J Immunol , vol.151 , pp. 2390-2398
    • Enk, A.H.1    Angeloni, V.L.2    Udey, M.C.3    Katz, S.I.4
  • 14
    • 0027239842 scopus 로고
    • IL-10 inhibits macrophage costimulatory activity by selectively inhibiting the up-regulation of B7 expression
    • Ding L et al. IL-10 inhibits macrophage costimulatory activity by selectively inhibiting the up-regulation of B7 expression. J Immunol 1993; 151: 1224-1234.
    • (1993) J Immunol , vol.151 , pp. 1224-1234
    • Ding, L.1
  • 15
    • 0028299069 scopus 로고
    • Interleukin-10 inhibits B7 and intercellular adhesion molecule-l expression on human monocytes
    • Willems F et al. Interleukin-10 inhibits B7 and intercellular adhesion molecule-l expression on human monocytes. Eur J Immunol 1994; 24: 1007-1009.
    • (1994) Eur J Immunol , vol.24 , pp. 1007-1009
    • Willems, F.1
  • 16
    • 0025820460 scopus 로고
    • IL-10: A novel cytotoxic T cell differentiation factor
    • Chen WF, Zlotnik A. IL-10: a novel cytotoxic T cell differentiation factor. J Immunol 1991; 147: 528-534.
    • (1991) J Immunol , vol.147 , pp. 528-534
    • Chen, W.F.1    Zlotnik, A.2
  • 17
    • 0026584291 scopus 로고
    • Interleukin 10 is a potent growth and differentiation factor for activated human B lymphocytes
    • Rousset F et al. Interleukin 10 is a potent growth and differentiation factor for activated human B lymphocytes. Proc Natl Acad Sci USA 1992; 89: 1890-1893.
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 1890-1893
    • Rousset, F.1
  • 18
    • 0025967870 scopus 로고
    • Interleukin 10: A novel stimulatory factor for mast cells and their progenitors
    • Thompson-Snipes L et al. Interleukin 10: a novel stimulatory factor for mast cells and their progenitors. J Exp Med 1991; 173: 507-510.
    • (1991) J Exp Med , vol.173 , pp. 507-510
    • Thompson-Snipes, L.1
  • 19
    • 0025224135 scopus 로고
    • Expression of interleukin-10 activity by EpsteinBarr virus protein BCRF1
    • Hsu D-H et al. Expression of interleukin-10 activity by EpsteinBarr virus protein BCRF1. Science 1990; 250: 830-832.
    • (1990) Science , vol.250 , pp. 830-832
    • Hsu, D.-H.1
  • 20
    • 0028122043 scopus 로고
    • Properties and functions of interleukin-10
    • Mosmann TR. Properties and functions of interleukin-10. Adv Immunol 1994; 56: 1-26.
    • (1994) Adv Immunol , vol.56 , pp. 1-26
    • Mosmann, T.R.1
  • 21
    • 0028346888 scopus 로고
    • Production of interleukin 10 fay islet cells accelerates immune-mediated destruction of beta cells in nonobese diabetic mice
    • Wogensen L, Lee MS, Sarvetnick N. Production of interleukin 10 fay islet cells accelerates immune-mediated destruction of beta cells in nonobese diabetic mice. J Exp Med 1994; 179: 1379-1384.
    • (1994) J Exp Med , vol.179 , pp. 1379-1384
    • Wogensen, L.1    Lee, M.S.2    Sarvetnick, N.3
  • 22
    • 0029100824 scopus 로고
    • Viral interleukin 10 (IL-10), the human herpes virus 4 cellular IL-10 homologue, induces local anergy to allogeneic and syngeneic tumors
    • Suzuki T et al. Viral interleukin 10 (IL-10), the human herpes virus 4 cellular IL-10 homologue, induces local anergy to allogeneic and syngeneic tumors. J Exp Med 1995; 182: 477-486.
    • (1995) J Exp Med , vol.182 , pp. 477-486
    • Suzuki, T.1
  • 23
    • 0027985597 scopus 로고
    • Gene transfer for transplantation: Prolongation of allograft survival with transforming growth factor-βl
    • Qin L et al. Gene transfer for transplantation: prolongation of allograft survival with transforming growth factor-βl. Ann Surg 1994; 220: 508-519.
    • (1994) Ann Surg , vol.220 , pp. 508-519
    • Qin, L.1
  • 24
    • 0029844582 scopus 로고    scopus 로고
    • Gene transfer of transforming growth factor-βl prolongs murine cardiac allograft survival by inhibiting cell-mediated immunity
    • Qin L, Ding Y, Bromberg JS. Gene transfer of transforming growth factor-βl prolongs murine cardiac allograft survival by inhibiting cell-mediated immunity. Hum Gene Ther 1996; 7: 1981-1988.
    • (1996) Hum Gene Ther , vol.7 , pp. 1981-1988
    • Qin, L.1    Ding, Y.2    Bromberg, J.S.3
  • 25
    • 0029856188 scopus 로고    scopus 로고
    • A new cationic liposome-DNA complex enhances the efficiency of arterial gene transfer in vivo
    • Stephan DJ et al. A new cationic liposome-DNA complex enhances the efficiency of arterial gene transfer in vivo. Hum Gene Ther 1996; 7: 1803-1812.
    • (1996) Hum Gene Ther , vol.7 , pp. 1803-1812
    • Stephan, D.J.1
  • 26
    • 0026680680 scopus 로고
    • Mobilization of T lymphocytes following cardiac transplantation. Evidence that CD4-positive cells are required for cytotoxic T lymphocyte activation, inflammatory endothelial development, graft infiltration, and acute allograft rejection
    • Bishop DK, Shelby J, Eichwald EJ. Mobilization of T lymphocytes following cardiac transplantation. Evidence that CD4-positive cells are required for cytotoxic T lymphocyte activation, inflammatory endothelial development, graft infiltration, and acute allograft rejection. Transplantation 1992; 53: 849-857.
    • (1992) Transplantation , vol.53 , pp. 849-857
    • Bishop, D.K.1    Shelby, J.2    Eichwald, E.J.3
  • 27
    • 0028018447 scopus 로고
    • Interleukin 10 up-regulates elastin gene expression in vivo and in vitro at the transcription level
    • Reitamo S et al. Interleukin 10 up-regulates elastin gene expression in vivo and in vitro at the transcription level. Biochem J 1994; 302: 331-333.
    • (1994) Biochem J , vol.302 , pp. 331-333
    • Reitamo, S.1
  • 28
    • 0025132571 scopus 로고
    • Site-specific gene expression in vivo by direct gene transfer into the arterial wall
    • Nabel EG, Plautz G, Nabel GJ. Site-specific gene expression in vivo by direct gene transfer into the arterial wall. Science 1990; 249: 1285-1288.
    • (1990) Science , vol.249 , pp. 1285-1288
    • Nabel, E.G.1    Plautz, G.2    Nabel, G.J.3
  • 29
    • 0028948817 scopus 로고
    • Direct gene transfer into donor hearts at the time of harvest
    • Ardehali A et al. Direct gene transfer into donor hearts at the time of harvest. J Thor Cardia Surg 1995; 109: 716-719.
    • (1995) J Thor Cardia Surg , vol.109 , pp. 716-719
    • Ardehali, A.1
  • 30
    • 0029569050 scopus 로고
    • Biologic modification of the immune response in mouse cardiac isografts using gene transfer
    • Fyfe Al et al. Biologic modification of the immune response in mouse cardiac isografts using gene transfer. J Heart Lung Transplant 1995; 14: S165-170.
    • (1995) J Heart Lung Transplant , vol.14
    • Al, F.1
  • 31
    • 0029889908 scopus 로고    scopus 로고
    • Ex vivo gene transfer to transplanted heart grafts using adenoviral vector
    • Gojo S et al. Ex vivo gene transfer to transplanted heart grafts using adenoviral vector. Transplant Proc 1996; 28: 1818-1819.
    • (1996) Transplant Proc , vol.28 , pp. 1818-1819
    • Gojo, S.1
  • 32
    • 0030066351 scopus 로고    scopus 로고
    • Cardiac gene transfer by intracoronary infusion of adenovirus vector-mediated reporter gene in the transplanted mouse heart
    • Lee J et al. Cardiac gene transfer by intracoronary infusion of adenovirus vector-mediated reporter gene in the transplanted mouse heart. J Thor Cardia Surg 1996; 111: 246-252.
    • (1996) J Thor Cardia Surg , vol.111 , pp. 246-252
    • Lee, J.1
  • 33
    • 0029798091 scopus 로고    scopus 로고
    • Adenovirus-mediated gene transfer using ex vivo perfusion of the heart graft
    • Shiraishi M et al. Adenovirus-mediated gene transfer using ex vivo perfusion of the heart graft. Surg Today 1996; 26: 624-628.
    • (1996) Surg Today , vol.26 , pp. 624-628
    • Shiraishi, M.1
  • 34
    • 0031001562 scopus 로고    scopus 로고
    • Ultrarapid, highly efficient viral gene transfer to the heart
    • Donahue JK et al. Ultrarapid, highly efficient viral gene transfer to the heart. Proc Natl Acad Sci USA 1997; 94: 4664-668.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 4664-4668
    • Donahue, J.K.1
  • 35
    • 0029987437 scopus 로고    scopus 로고
    • Adenovirus-mediated gene transfer into rat cardiac allografts
    • Wang J, Ma Y; Knechtle SJ. Adenovirus-mediated gene transfer into rat cardiac allografts. Transplantation 1996, 61: 1726-1729.
    • (1996) Transplantation , vol.61 , pp. 1726-1729
    • Wang, J.1    Ma, Y.2    Knechtle, S.J.3
  • 36
    • 0030764114 scopus 로고    scopus 로고
    • Adenovirus-mediated gene transfer of viral interleukin 10 inhibits the immune response to both alloantigen and adenoviral antigen
    • Qin L et al. Adenovirus-mediated gene transfer of viral interleukin 10 inhibits the immune response to both alloantigen and adenoviral antigen. Hum Gene Ther 1997; 8. 1365-1374.
    • (1997) Hum Gene Ther , vol.8 , pp. 1365-1374
    • Qin, L.1
  • 37
    • 0027209139 scopus 로고
    • Leukocyte extravasation into the pancreatic tissue in transgenic mice expressing interleukin 10 in the islets of Langerhans
    • Wogensen L, Huang X, Sarvetnick N. Leukocyte extravasation into the pancreatic tissue in transgenic mice expressing interleukin 10 in the islets of Langerhans. J Exp Med 1993; 178: 175-185.
    • (1993) J Exp Med , vol.178 , pp. 175-185
    • Wogensen, L.1    Huang, X.2    Sarvetnick, N.3
  • 38
    • 0028280636 scopus 로고
    • Pancreatic islet production of murine interleukin10 does not inhibit immune-mediated tissue destruction
    • Lee MS et al. Pancreatic islet production of murine interleukin10 does not inhibit immune-mediated tissue destruction. J Clin Invest 1994; 93: 1332-1338.
    • (1994) J Clin Invest , vol.93 , pp. 1332-1338
    • Lee, M.S.1
  • 39
    • 0030449531 scopus 로고    scopus 로고
    • Decreased alloreactivity to human islets secreting recombinant viral interleukin 10
    • Benhamou PY et al. Decreased alloreactivity to human islets secreting recombinant viral interleukin 10. Transplantation 1996; 62: 1306-1312.
    • (1996) Transplantation , vol.62 , pp. 1306-1312
    • Benhamou, P.Y.1
  • 40
    • 0029150496 scopus 로고
    • Transduction of hepatic allografts achieves local levels of viral IL-10 which suppress alloreactivity in vitro
    • Drazan KE et al. Transduction of hepatic allografts achieves local levels of viral IL-10 which suppress alloreactivity in vitro. J Surg Res 1995; 59: 219-223.
    • (1995) J Surg Res , vol.59 , pp. 219-223
    • Drazan, K.E.1
  • 41
    • 0031193452 scopus 로고    scopus 로고
    • Endogenous versus exogenous IL-10 in postoperative intraperitoneal adhesion formation in a murine model
    • Holschneider CH et al. Endogenous versus exogenous IL-10 in postoperative intraperitoneal adhesion formation in a murine model. J Surg Res 1997; 70: 138-143.
    • (1997) J Surg Res , vol.70 , pp. 138-143
    • Holschneider, C.H.1
  • 42
    • 0030971484 scopus 로고    scopus 로고
    • Interleukin-10 inhibits activation of coagulation and fibrinolysis during human endotoxemia
    • Pajkrt D. Interleukin-10 inhibits activation of coagulation and fibrinolysis during human endotoxemia. Blood 1997; 89: 2701-2705.
    • (1997) Blood , vol.89 , pp. 2701-2705
    • Pajkrt, D.1
  • 43
    • 0025104027 scopus 로고
    • TGF-β stimulation and inhibition of cell proliferation: New mechanistic insights
    • Moses HL, Yang EY, Pietenpol JA. TGF-β stimulation and inhibition of cell proliferation: new mechanistic insights. Cell 1990; 63: 245-247.
    • (1990) Cell , vol.63 , pp. 245-247
    • Moses, H.L.1    Yang, E.Y.2    Pietenpol, J.A.3
  • 44
    • 0025068931 scopus 로고
    • Transforming growth factor-β and its actions on cellular growth and differentiation
    • Nilsen-Hamilton M. Transforming growth factor-β and its actions on cellular growth and differentiation. Curr Top Develop Biol 1990; 24: 95-136.
    • (1990) Curr Top Develop Biol , vol.24 , pp. 95-136
    • Nilsen-Hamilton, M.1
  • 45
    • 0027138877 scopus 로고
    • Glomerulosclerosis induced by in vivo transfection of transforming growth factor-β or platelet-derived growth factor gene into rat kidney
    • Isaka Y et al. Glomerulosclerosis induced by in vivo transfection of transforming growth factor-β or platelet-derived growth factor gene into rat kidney. J Clin Invest 1993; 92: 2597-2601.
    • (1993) J Clin Invest , vol.92 , pp. 2597-2601
    • Isaka, Y.1
  • 46
    • 0028222954 scopus 로고
    • Efficient and sustained gene expression in primary T lymphocytes and primary and cultured tumor cells mediated by adeno-associated virus plasmid DNA complexed to cationic liposomes
    • Philip R et al. Efficient and sustained gene expression in primary T lymphocytes and primary and cultured tumor cells mediated by adeno-associated virus plasmid DNA complexed to cationic liposomes. Mol Cell Biol 1994; 14: 2411-2418.
    • (1994) Mol Cell Biol , vol.14 , pp. 2411-2418
    • Philip, R.1
  • 47
    • 0015866545 scopus 로고
    • Primarily vascularized allografts of hearts in mice
    • Corry RJ, Winn HS, Russell PS. Primarily vascularized allografts of hearts in mice. Transplantation 1973; 16: 343-350.
    • (1973) Transplantation , vol.16 , pp. 343-350
    • Corry, R.J.1    Winn, H.S.2    Russell, P.S.3
  • 48
    • 0028158319 scopus 로고
    • High levels of interleukin 10 production in vivo are associated with tolerance in SCID patients transplanted with HLA mismatched hematopoietic stem cells
    • Bacchetta R et al. High levels of interleukin 10 production in vivo are associated with tolerance in SCID patients transplanted with HLA mismatched hematopoietic stem cells. J Exp Med 1994; 179: 493-502.
    • (1994) J Exp Med , vol.179 , pp. 493-502
    • Bacchetta, R.1
  • 49
    • 0024536767 scopus 로고
    • Limiting dilution analysis for alloreactive, TCGF-secreting T cells: LDA methods that discriminate between unstimulated precursor T cells and in vivo alloactivated T cells
    • Bishop DK, Orosz CG. Limiting dilution analysis for alloreactive, TCGF-secreting T cells: LDA methods that discriminate between unstimulated precursor T cells and in vivo alloactivated T cells. Transplantation 1989; 47: 671-677.
    • (1989) Transplantation , vol.47 , pp. 671-677
    • Bishop, D.K.1    Orosz, C.G.2
  • 50
    • 0024576301 scopus 로고
    • Development and evaluation of an LDA technique that can discriminate in vivo alloactivated CTL from their naive CTL precursors
    • Orosz CG, Horstemeyer B, Zinn NE, Bishop DK. Development and evaluation of an LDA technique that can discriminate in vivo alloactivated CTL from their naive CTL precursors. Transplantation 1989; 47- 189-194.
    • (1989) Transplantation , vol.47 , pp. 189-194
    • Orosz, C.G.1    Horstemeyer, B.2    Zinn, N.E.3    Bishop, D.K.4
  • 51
    • 0019468220 scopus 로고
    • Limiting dilution assays for the determination of immunocompetent cell frequencies. I. Data analysis
    • Taswell C. Limiting dilution assays for the determination of immunocompetent cell frequencies. I. Data analysis. J Immunol 1981; 126: 1614-1619.
    • (1981) J Immunol , vol.126 , pp. 1614-1619
    • Taswell, C.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.