Targeted gene therapy with CD40Ig to induce long-term acceptance of liver allografts

Surgery

Volumn 132, Issue 2, 2002, Pages 149-156

  Chang, George J ^a   Liu, Tao ^a   Feng, Sandy ^a   Bedolli, Melanie ^a   O'Rourke, Robert W ^a   Schmidt, Gregory ^a   Roberts, John P ^a   Stock, Peter G ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD40 ANTIGEN; CD40 LIGAND; CD40IG ANTIGEN; IMMUNOGLOBULIN FC FRAGMENT; IMMUNOGLOBULIN G2A; UNCLASSIFIED DRUG;

ADENOVIRUS; ALLOGRAFT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIGEN PRESENTING CELL; ARTICLE; CONTROLLED STUDY; GENE EXPRESSION; GENE THERAPY; GENE TRANSFER; GENETIC TRANSDUCTION; GRAFT SURVIVAL; IMMUNE RESPONSE; IMMUNOGLOBULIN BLOOD LEVEL; LIVER TRANSPLANTATION; LYMPHOCYTIC INFILTRATION; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SKIN TRANSPLANTATION; T LYMPHOCYTE; TRANSGENE; VIRUS PARTICLE; VIRUS RECOMBINANT;

EID: 0036673417     PISSN: 00396060     EISSN: None     Source Type: Journal    
DOI: 10.1067/msy.2002.125169     Document Type: Article

References (25)

1. Multiple vectors effectively achieve gene transfer in a murine cardiac transplantation model. Immunosuppression with TGF-beta 1 or vIL-10
2. Adenovirus-mediated gene transfer into cold-preserved liver allografts: Survival pattern and unresponsiveness following transduction with CTLA4Ig
3. Prolonged xenograft survival of islets infected with small doses of adenovirus expressing CTLA4Ig
4. Adenovirus-mediated gene transfer in the transplant setting. II. Successful expression of transferred cDNA in syngeneic liver grafts
5. A cell culture model for T lymphocyte clonal anergy
6. CD40-gp39 interactions play a critical role during allograft rejection. Suppression of allograft rejection by blockade of the CD40-gp39 pathway
7. New perspectives of CD28-B7-mediated T-cell costimulation
8. CTLA-4 is a second receptor for the B cell activation antigen BT
9. Functional CD40 on B lymphocytes and dendritic cells
10. Properties of mouse CD40: Cellular distribution of CD40 and B cell activation by monoclonal anti-mouse CD40 antibodies
11. A 39-kDa protein on activated helper T-cells binds CD40 and transduces the signal for cognate activation of B cells
12. Induction of immunologic tolerance for transplantation
13. Treatment with humanized monoclonal antibody against CD154 prevents acute renal allograft rejection in nonhuman primates
14. Long-term survival and function of intrahepatic islet allografts in baboons treated with humanized anti-CD154
15. Long-term survival and function of intrahepatic islet allografts in rhesus monkeys treated with humanized anti-CD154
16. Long-term acceptance of skin and cardiac allografts after blocking CD40 and CD28 pathways
17. Long-term survival of xenogeneic pancreatic islet grafts induced by CTLA41g
18. A surgical experience with five hundred thirty liver transplants in the rat
19. Construction of adenovirus vectors through Cre-lox recombination
20. A dendritic cell line genetically modified to express CTLA4-IG as a means to prolong islet allograft survival
21. Survival of mouse pancreatic islet allografts in recipients treated with allogeneic small lymphocytes and antibody to CD40 ligand
22. Induction of islet transplantation tolerance using donor specific transfusion and anti-CD154 monoclonal antibody
23. Prolonged survival of mouse skin allografts in recipients treated with donor splenocytes and antibody to CD40 ligand
24. The roles of CD28 and CD40 ligand in T-cell activation and tolerance
25. The role of CD40 ligand in costimulation and T-cell activation