Possible mechanism on enhanced carcinogenesis of genotoxic carcinogens and unsolved mechanisms on lesser carcinogenic susceptibility to some carcinogens in rasH2 mice

Journal of Toxicological Sciences

Volumn 28, Issue 5, 2003, Pages 371-383

  Mitsumori, Kunitoshi ^a  

^a TOKYO UNIVERSITY OF AGRICULTURE AND TECHNOLOGY   (Japan)

Author keywords

Enhanced carcinogenicity; Genotoxic carcinogen; Mechanism; rasH2 mice

Indexed keywords

1,2 DIMETHYLHYDRAZINE; 4 HYDROXYAMINOQUINOLINE 1 OXIDE; 4 NITROQUINOLINE 1 OXIDE; ANILINE DERIVATIVE; CARBAMIC ACID DERIVATIVE; CARCINOGEN; CHRYSENE DERIVATIVE; CYCLOHEXENE DERIVATIVE; CYCLOPHOSPHAMIDE; DIETHYLNITROSAMINE; DIMETHYLBENZ[A]ANTHRACENE; MELPHALAN; METHYLAZOXYMETHANOL; METHYLNITRONITROSOGUANIDINE; METHYLNITROSOUREA; NITROSAMINE; PHENACETIN; PROCARBAZINE; THIOTEPA; URETHAN; VINYL DERIVATIVE;

ANGIOSARCOMA; ANIMAL MODEL; CARCINOGENESIS; CHEMICAL CARCINOGENESIS; GENE MUTATION; GENOTOXICITY; LIVER CARCINOMA; LUNG CARCINOMA; MOUSE; NONHUMAN; ONCOGENE C H RAS; POINT MUTATION; POLYMERASE CHAIN REACTION; PROMOTER REGION; REVIEW; SINGLE STRAND CONFORMATION POLYMORPHISM; SKIN PAPILLOMA; SOMATIC MUTATION; STOMACH TUMOR; TRANSGENIC MOUSE; TUMOR SUPPRESSOR GENE;

ANIMALIA; MUS MUSCULUS;

EID: 1642512644     PISSN: 03881350     EISSN: 18803989     Source Type: Journal    
DOI: 10.2131/jts.28.371     Document Type: Review

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