Mutation and overexpression of the transgene in ethylnitrosourea-induced tumors in mice carrying a human prototype c-Ha-ras gene

Toxicologic Pathology

Volumn 31, Issue 5, 2003, Pages 491-495

  Toyosawa, Kaoru ^a   Tanaka, Kohji ^a   Imai, Toshio ^b   Yasuhara, Kazuo ^b   Koujitani, Takatoshi ^a,b   Hirose, Masao ^b   Mitsumori, Kunitoshi ^b,c  

^a DAINIPPON SUMITOMO PHARMA CO LTD   (Japan)

^b NATIONAL INSTITUTE OF HEALTH SCIENCES   (Japan)

^c TOKYO UNIVERSITY OF AGRICULTURE AND TECHNOLOGY   (Japan)

Author keywords

Ethylnitrosourea (ENU); Human prototype c Ha ras transgenic mouse; Mutation; Overexpression; rasH2 mouse; Transgene

Indexed keywords

ESTRADIOL BENZOATE; ETHYLNITROSOUREA; MESSENGER RNA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CHEMICAL CARCINOGENESIS; CODON; CONTROLLED STUDY; FEMALE; GENE AMPLIFICATION; GENE FUNCTION; GENE MUTATION; GENE OVEREXPRESSION; HUMAN; LUNG ADENOCARCINOMA; NONHUMAN; ONCOGENE C H RAS; PRIORITY JOURNAL; PROTO ONCOGENE; SKIN CARCINOMA; SQUAMOUS CELL CARCINOMA; STOMACH CARCINOMA; TRANSGENE;

ADENOCARCINOMA; ANIMALS; CARCINOGENS; CARCINOMA, SQUAMOUS CELL; CODON; ETHYLNITROSOUREA; FEMALE; GENE EXPRESSION; GENES, RAS; HUMANS; LIVER; LUNG NEOPLASMS; MICE; MICE, TRANSGENIC; MUTATION; RNA, MESSENGER; SKIN NEOPLASMS; STOMACH NEOPLASMS; TRANSGENES;

ANIMALIA; MUS MUSCULUS;

EID: 0141453257     PISSN: 01926233     EISSN: None     Source Type: Journal    
DOI: 10.1080/01926230309796     Document Type: Article

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