-
1
-
-
0023858438
-
Enhancing effect of various hepatocarcinogens on induction of preneoplastic glutathione S-transferase placental form positive foci in rats - An approach for a new medium-term bioassay system
-
Ito,N., Tsuda,H., Tatematsu,M. er al. (1988) Enhancing effect of various hepatocarcinogens on induction of preneoplastic glutathione S-transferase placental form positive foci in rats - an approach for a new medium-term bioassay system. Carcinogenesis, 9, 387-394.
-
(1988)
Carcinogenesis
, vol.9
, pp. 387-394
-
-
Ito, N.1
Tsuda, H.2
Tatematsu, M.3
-
2
-
-
0024906387
-
Medium-term bioassay system for detection of carcinogens and modifiers of hepatocarcinogenesis utilizing the GST-P positive liver cell focus as an endpoint marker
-
Ito,N., Tatematsu,M., Hasegawa,R. and Tsuda,H. (1989) Medium-term bioassay system for detection of carcinogens and modifiers of hepatocarcinogenesis utilizing the GST-P positive liver cell focus as an endpoint marker. Toxicol. Pathol., 17, 630-641.
-
(1989)
Toxicol. Pathol.
, vol.17
, pp. 630-641
-
-
Ito, N.1
Tatematsu, M.2
Hasegawa, R.3
Tsuda, H.4
-
3
-
-
0027062789
-
Liver medium-term bioassay in rats for screening of carcinogens and modifying factors in hepatocarcinogenesis
-
Hasegawa,R. and Ito,N. (1992) Liver medium-term bioassay in rats for screening of carcinogens and modifying factors in hepatocarcinogenesis. Fd Chem. Toxicol., 30, 979-992.
-
(1992)
Fd Chem. Toxicol.
, vol.30
, pp. 979-992
-
-
Hasegawa, R.1
Ito, N.2
-
4
-
-
0024443942
-
Transgenic mice as future tools in risk assessment
-
Cordaro,J.C. (1989) Transgenic mice as future tools in risk assessment. Risk Analysis, 9, 157-168.
-
(1989)
Risk Analysis
, vol.9
, pp. 157-168
-
-
Cordaro, J.C.1
-
5
-
-
0028295634
-
Transgenic animals in toxicology
-
Goldsworthy,T., Recio,L., Brown,K., Donehower,L.A., Mirsalis,J.C., Tennant,R.W. and Purchase,I.F.H. (1994) Transgenic animals in toxicology. Fundam. Appl. Toxicol., 22, 8-19.
-
(1994)
Fundam. Appl. Toxicol.
, vol.22
, pp. 8-19
-
-
Goldsworthy, T.1
Recio, L.2
Brown, K.3
Donehower, L.A.4
Mirsalis, J.C.5
Tennant, R.W.6
Purchase, I.F.H.7
-
6
-
-
0021720781
-
Spontaneous mammary adenocarcinomas in transgenic mice that carry and express MTV/mvc fusion genes
-
Stewart,T.A., Pattengale,P.K. and Leder,P. (1984) Spontaneous mammary adenocarcinomas in transgenic mice that carry and express MTV/mvc fusion genes. Cell, 38, 627-637.
-
(1984)
Cell
, vol.38
, pp. 627-637
-
-
Stewart, T.A.1
Pattengale, P.K.2
Leder, P.3
-
7
-
-
0025372023
-
Development of mammary hyperplasia and neoplasia in MMTV-TGFα transgenic mice
-
Matsui,Y., Halter,S.A., Holt,J.T., Hogan,B.L.M. and Coffey,R.J. (1990) Development of mammary hyperplasia and neoplasia in MMTV-TGFα transgenic mice. Cell, 61, 1147-1155.
-
(1990)
Cell
, vol.61
, pp. 1147-1155
-
-
Matsui, Y.1
Halter, S.A.2
Holt, J.T.3
Hogan, B.L.M.4
Coffey, R.J.5
-
8
-
-
0028327183
-
Acceleration of mammary neoplasia in transforming growth factor α transgenic mice by 7,12-dimethylbenzanthracene
-
Coffey,R.J.,Jr. Meise,K.S., Matsui,Y, Hogan,B.L.M., Dempsey,P.J. and Halter,S.A. (1994) Acceleration of mammary neoplasia in transforming growth factor α transgenic mice by 7,12-dimethylbenzanthracene. Cancer Res., 54, 1678-1683.
-
(1994)
Cancer Res.
, vol.54
, pp. 1678-1683
-
-
Coffey Jr., R.J.1
Meise, K.S.2
Matsui, Y.3
Hogan, B.L.M.4
Dempsey, P.J.5
Halter, S.A.6
-
9
-
-
0024403228
-
Oncogene-induced liver neoplasia in transgenic mice
-
Sandgren,E.P., Quaife,C.J., Pinkert,C.A., Palmiter,R.D. and Brinster,R.L. (1989) Oncogene-induced liver neoplasia in transgenic mice. Oncogene, 4, 715-724.
-
(1989)
Oncogene
, vol.4
, pp. 715-724
-
-
Sandgren, E.P.1
Quaife, C.J.2
Pinkert, C.A.3
Palmiter, R.D.4
Brinster, R.L.5
-
10
-
-
0024399305
-
Transgenic mouse model for human gastric carcinoma
-
Koike,K., Hinrichs,S.H., Isselbacher,K.J. and Jay,G. (1989) Transgenic mouse model for human gastric carcinoma. Proc. Natl Acad. Sci. USA, 86, 5615-5619.
-
(1989)
Proc. Natl Acad. Sci. USA
, vol.86
, pp. 5615-5619
-
-
Koike, K.1
Hinrichs, S.H.2
Isselbacher, K.J.3
Jay, G.4
-
11
-
-
0022397571
-
A transgenic mouse model of the chronic hepatitis B surface antigen carrier state
-
Chisari,F.V., Pinkert,C.A., Milich,D.R., Filippi,P., McLachlan,A., Palmiter, R.D. and Brinster.R.L. (1985) A transgenic mouse model of the chronic hepatitis B surface antigen carrier state. Science, 230, 1157-1160.
-
(1985)
Science
, vol.230
, pp. 1157-1160
-
-
Chisari, F.V.1
Pinkert, C.A.2
Milich, D.R.3
Filippi, P.4
McLachlan, A.5
Palmiter, R.D.6
Brinster, R.L.7
-
12
-
-
0023228105
-
A transgenic mouse model for human neurofibromatosis
-
Hinrichs,S.H., Nerenberg,M., Reynolds,R.K., Khoury,G. and Jay,G. (1987) A transgenic mouse model for human neurofibromatosis. Science, 237, 1340-1343.
-
(1987)
Science
, vol.237
, pp. 1340-1343
-
-
Hinrichs, S.H.1
Nerenberg, M.2
Reynolds, R.K.3
Khoury, G.4
Jay, G.5
-
14
-
-
0021885503
-
6-Nitrochrysene is a potent tumorigen in newborn mice
-
Busby, W.F.J., Gamer,R.C., Chow,F.L., Martin,C.N., Stevens,E.K., Newbeme, P.M. and Wogan,G.N. (1985) 6-Nitrochrysene is a potent tumorigen in newborn mice. Carcinogenesis. 6, 801-803.
-
(1985)
Carcinogenesis
, vol.6
, pp. 801-803
-
-
Busby, W.F.J.1
Gamer, R.C.2
Chow, F.L.3
Martin, C.N.4
Stevens, E.K.5
Newbeme, P.M.6
Wogan, G.N.7
-
15
-
-
0023911068
-
Dose-response relationships of the tumorigenicity of cyclopenta[cd]pyrene, benzo[a]pyrene and 6-nitrochrysene in a newborn mouse lung adenoma bioassay
-
Busby,W.F.J., Stevens,E.K., Kellenbach,E.R., Cornelisse,J. and Lugtenburg,J. (1988) Dose-response relationships of the tumorigenicity of cyclopenta[cd]pyrene, benzo[a]pyrene and 6-nitrochrysene in a newborn mouse lung adenoma bioassay. Carcinogenesis, 9, 741-746.
-
(1988)
Carcinogenesis
, vol.9
, pp. 741-746
-
-
Busby, W.F.J.1
Stevens, E.K.2
Kellenbach, E.R.3
Cornelisse, J.4
Lugtenburg, J.5
-
16
-
-
0024494431
-
Comparative tumorigenicity of 6-nitrochrysene and its metabolites in newborn mice
-
El-Bayoumy,K., Shiue,G.-H. and Hecht,S.S. (1989) Comparative tumorigenicity of 6-nitrochrysene and its metabolites in newborn mice. Carcinogenesis. 10, 369-372.
-
(1989)
Carcinogenesis
, vol.10
, pp. 369-372
-
-
El-Bayoumy, K.1
Shiue, G.-H.2
Hecht, S.S.3
-
17
-
-
0026785360
-
Supercritical fluid extraction of nitrated polycyclic aromatic hydrocarbons and polycyclic aromatic hydrocarbons from diesel exhaust paniculate matter
-
Paschke,T., Hawthorne,S.B. and Miller,D.J. (1992) Supercritical fluid extraction of nitrated polycyclic aromatic hydrocarbons and polycyclic aromatic hydrocarbons from diesel exhaust paniculate matter. J. Chromatogr., 609, 333-340.
-
(1992)
J. Chromatogr.
, vol.609
, pp. 333-340
-
-
Paschke, T.1
Hawthorne, S.B.2
Miller, D.J.3
-
18
-
-
84910748811
-
Induction of pulmonary tumors in mice with ethyl carbamate (urethane)
-
Nettleship,A., Henshaw,P.S. and Meyer,H.L. (1943) Induction of pulmonary tumors in mice with ethyl carbamate (urethane). J. Natl Cancer Inst., 4, 309-319.
-
(1943)
J. Natl Cancer Inst.
, vol.4
, pp. 309-319
-
-
Nettleship, A.1
Henshaw, P.S.2
Meyer, H.L.3
-
19
-
-
0025121594
-
Most tumors in transgenic mice with human c-Ha-ras gene contained somatically activated transgenes
-
Saitoh,A., Kimura,M., Takahashi,R., Yokoyama,M., NomuraT., Izawa,M., Sekiya,T., Nishimura,S. and Katsuki,M. (1990) Most tumors in transgenic mice with human c-Ha-ras gene contained somatically activated transgenes. Oncogene, 5, 1195-1200.
-
(1990)
Oncogene
, vol.5
, pp. 1195-1200
-
-
Saitoh, A.1
Kimura, M.2
Takahashi, R.3
Yokoyama, M.4
Nomura, T.5
Izawa, M.6
Sekiya, T.7
Nishimura, S.8
Katsuki, M.9
-
20
-
-
0345353415
-
The nitration of diphenyl, chrysene, benzo[a]pyrene and anthanthene
-
Dewar,M.J.S., Mole,T., Urch,D.S. and Warford,E.W.T. (1956) The nitration of diphenyl, chrysene, benzo[a]pyrene and anthanthene. J. Chem. Soc., 3572-3575.
-
(1956)
J. Chem. Soc.
, pp. 3572-3575
-
-
Dewar, M.J.S.1
Mole, T.2
Urch, D.S.3
Warford, E.W.T.4
-
21
-
-
0024756969
-
Rapid sensitive detection of point mutations and DNA polymorphisms using the polymerase chain reaction
-
Orita,M., Suzuki,Y., Sekiya,T. and Hayashi,K. (1989) Rapid sensitive detection of point mutations and DNA polymorphisms using the polymerase chain reaction. Genomics, 5, 874-879.
-
(1989)
Genomics
, vol.5
, pp. 874-879
-
-
Orita, M.1
Suzuki, Y.2
Sekiya, T.3
Hayashi, K.4
-
22
-
-
0025293818
-
Detection of ras gene mutations in human lung cancers by single-strand conformation polymorphism analysis of polymerase chain reaction products
-
Suzuki,Y., Orita,M., Shiraishi,M., Hayashi,K. and Sekiya,T. (1990) Detection of ras gene mutations in human lung cancers by single-strand conformation polymorphism analysis of polymerase chain reaction products. Oncogene, 5, 1037-1043.
-
(1990)
Oncogene
, vol.5
, pp. 1037-1043
-
-
Suzuki, Y.1
Orita, M.2
Shiraishi, M.3
Hayashi, K.4
Sekiya, T.5
-
23
-
-
0028245344
-
Relationships of DNA adduct formation, K-ras activating mutations and tumorigenic activities of 6-nitrochrysene and its metabolites in the lungs of CD-1 mice
-
Li,E.E., Heflich,R.H., Bucci,T.J., Manjanatha,M.G., Blaydes,B.S. and Delclos,K.B. (1994) Relationships of DNA adduct formation, K-ras activating mutations and tumorigenic activities of 6-nitrochrysene and its metabolites in the lungs of CD-1 mice. Carcinogenesis, 15, 1377-1385.
-
(1994)
Carcinogenesis
, vol.15
, pp. 1377-1385
-
-
Li, E.E.1
Heflich, R.H.2
Bucci, T.J.3
Manjanatha, M.G.4
Blaydes, B.S.5
Delclos, K.B.6
-
24
-
-
0025670013
-
Specific Ki-ras codon 61 mutations may determine the development of urethane-induced mouse lung adenomas or adenocarcinomas
-
Nuzum,E.O., Malkinson,A.M. and Beer,D.G. (1990) Specific Ki-ras codon 61 mutations may determine the development of urethane-induced mouse lung adenomas or adenocarcinomas. Mol. Carcinogen., 3, 287-295.
-
(1990)
Mol. Carcinogen.
, vol.3
, pp. 287-295
-
-
Nuzum, E.O.1
Malkinson, A.M.2
Beer, D.G.3
-
25
-
-
0026538639
-
Multiple molecular alterations in mouse lung tumors
-
Re,F.C., Manenti,G., Borrello,M.G., Colombo,M.P., Fisher,J.H., Pierotti, M.A., Porta,G.D. and Dragani,T.A. (1992) Multiple molecular alterations in mouse lung tumors. Mol. Carcinogen., 5, 155-160.
-
(1992)
Mol. Carcinogen.
, vol.5
, pp. 155-160
-
-
Re, F.C.1
Manenti, G.2
Borrello, M.G.3
Colombo, M.P.4
Fisher, J.H.5
Pierotti, M.A.6
Porta, G.D.7
Dragani, T.A.8
-
26
-
-
0007142725
-
Activation of the Ki-ras protooncogene in spontaneously occurring and chemically induced lung tumors of the strain A mouse
-
You,M., Candrian,U., Maronpot,R.R., Stoner,G.D. and Anderson,M.W. (1989) Activation of the Ki-ras protooncogene in spontaneously occurring and chemically induced lung tumors of the strain A mouse. Proc. Natl Acad. Sci. USA, 86, 3070-3074.
-
(1989)
Proc. Natl Acad. Sci. USA
, vol.86
, pp. 3070-3074
-
-
You, M.1
Candrian, U.2
Maronpot, R.R.3
Stoner, G.D.4
Anderson, M.W.5
-
27
-
-
0024437222
-
Relationship between the formation of promutagenic adducts and the activation of the K-ras protooncogene in lung tumors from A/J mice treated with nitrosamines
-
Belinsky,S.A., Devereux,T.R., Maronpot,R.R., Stoner,G.D. and Anderson,M.W. (1989) Relationship between the formation of promutagenic adducts and the activation of the K-ras protooncogene in lung tumors from A/J mice treated with nitrosamines. Cancer Res., 49, 5305-5311.
-
(1989)
Cancer Res.
, vol.49
, pp. 5305-5311
-
-
Belinsky, S.A.1
Devereux, T.R.2
Maronpot, R.R.3
Stoner, G.D.4
Anderson, M.W.5
-
28
-
-
0026096577
-
Role of ras protooncogene activation in the formation of spontaneous and nitrosamine-induced lung tumors in the resistant C3H mouse
-
Devereux,T.R., Anderson,M.W. and Belinsky,S.A. (1991) Role of ras protooncogene activation in the formation of spontaneous and nitrosamine-induced lung tumors in the resistant C3H mouse. Carcinogenesis, 12, 299-303.
-
(1991)
Carcinogenesis
, vol.12
, pp. 299-303
-
-
Devereux, T.R.1
Anderson, M.W.2
Belinsky, S.A.3
-
29
-
-
0027332477
-
6-methylguanine DNA adduct levels and Ki-ras activation in lung tumors from resistant and susceptible mouse strains
-
6-methylguanine DNA adduct levels and Ki-ras activation in lung tumors from resistant and susceptible mouse strains. Mol. Carcinogen., 8, 177-185.
-
(1993)
Mol. Carcinogen.
, vol.8
, pp. 177-185
-
-
Devereux, T.R.1
Belinsky, S.A.2
Maronpot, R.R.3
White, C.M.4
Hegi, M.E.5
Patel, A.C.6
Foley, J.F.7
Greenwell, A.8
Anderson, M.W.9
-
30
-
-
0023707058
-
Incidence and possible clinical significance of K-ras oncogene activation in adenocarcinoma of the human lung
-
Rodenhuis,S., Slebos,R.J.C., Boot,A.J.M., Evers,S.G., Mooi,W.J., Wagenaar,S.S., van Bodegom,P.C. and Bos,J.L. (1988) Incidence and possible clinical significance of K-ras oncogene activation in adenocarcinoma of the human lung. Cancer Res., 48, 5738-5741.
-
(1988)
Cancer Res.
, vol.48
, pp. 5738-5741
-
-
Rodenhuis, S.1
Slebos, R.J.C.2
Boot, A.J.M.3
Evers, S.G.4
Mooi, W.J.5
Wagenaar, S.S.6
Van Bodegom, P.C.7
Bos, J.L.8
-
31
-
-
0028068406
-
Site-specific mutation of the human c-Ha-ras transgene induced by dimethylbenzanthracene causes tissue-specific tumors in mice
-
Doi,S.-T., Kimura,M. and Katsuki,M. (1994) Site-specific mutation of the human c-Ha-ras transgene induced by dimethylbenzanthracene causes tissue-specific tumors in mice. Jpn. J. Cancer Res., 85, 801-807.
-
(1994)
Jpn. J. Cancer Res.
, vol.85
, pp. 801-807
-
-
Doi, S.-T.1
Kimura, M.2
Katsuki, M.3
-
32
-
-
0026603434
-
Induction of colon adenocarcinomas in CD rats and lung adenomas in ICR mice by 6-nitrochrysene: Comparison of carcinogenicity and arylhydrocarbon hydroxylase induction in the target organs of each species
-
Imaida,K., Uneyama,C., Ogasawara,H., Hayashi,S., Fukuhara,K., Miyata, N. and Takahashi,M. (1992) Induction of colon adenocarcinomas in CD rats and lung adenomas in ICR mice by 6-nitrochrysene: comparison of carcinogenicity and arylhydrocarbon hydroxylase induction in the target organs of each species. Cancer Res., 52, 1542-1545.
-
(1992)
Cancer Res.
, vol.52
, pp. 1542-1545
-
-
Imaida, K.1
Uneyama, C.2
Ogasawara, H.3
Hayashi, S.4
Fukuhara, K.5
Miyata, N.6
Takahashi, M.7
-
33
-
-
0028178813
-
Caloric restriction profoundly inhibits liver tumor formation after initiation by 6-nitrochrysene in male mice
-
Fu,P.P., Dooley,K.L., Von Tungeln,L.S., Bucci,T., Hart,R.W. and Kadlubar,F.F. (1994) Caloric restriction profoundly inhibits liver tumor formation after initiation by 6-nitrochrysene in male mice. Carcinogenesis, 15, 159-161.
-
(1994)
Carcinogenesis
, vol.15
, pp. 159-161
-
-
Fu, P.P.1
Dooley, K.L.2
Von Tungeln, L.S.3
Bucci, T.4
Hart, R.W.5
Kadlubar, F.F.6
-
34
-
-
0027291195
-
Induction of mammary cancer by 6-nitrochrysene in female CD rats
-
El-Bayoumy,K., Rivenson,A., Upadhyaya,P., Chae,Y.-H. and Hecht,S.S. (1993) Induction of mammary cancer by 6-nitrochrysene in female CD rats. Cancer Res., 53, 3719-3722.
-
(1993)
Cancer Res.
, vol.53
, pp. 3719-3722
-
-
El-Bayoumy, K.1
Rivenson, A.2
Upadhyaya, P.3
Chae, Y.-H.4
Hecht, S.S.5
-
35
-
-
0026503353
-
Chemically induced forestomach papillomas in transgenic mice carry mutant human c-Ha-ras transgenes
-
Ando,K., Saitoh,A., Hino,O., Takahashi,R., Kimura,M. and Katsuki,M. (1992) Chemically induced forestomach papillomas in transgenic mice carry mutant human c-Ha-ras transgenes. Cancer Res., 52, 978-982.
-
(1992)
Cancer Res.
, vol.52
, pp. 978-982
-
-
Ando, K.1
Saitoh, A.2
Hino, O.3
Takahashi, R.4
Kimura, M.5
Katsuki, M.6
-
36
-
-
0028241533
-
Activation of Raf as a result of recruitment to the plasma membrane
-
Stokoe,D., Macdonald,S.G., Cadwallader,K., Symons,M. and Hancock,J.F. (1994) Activation of Raf as a result of recruitment to the plasma membrane. Science, 264, 1465-1467.
-
(1994)
Science
, vol.264
, pp. 1465-1467
-
-
Stokoe, D.1
Macdonald, S.G.2
Cadwallader, K.3
Symons, M.4
Hancock, J.F.5
-
37
-
-
0028272507
-
Requirement for Ras in Raf activation is overcome by targeting Raf to the plasma membrane
-
Leevers,S.J., Paterson,H.F. and Marshall.C.J. (1994) Requirement for Ras in Raf activation is overcome by targeting Raf to the plasma membrane. Nature, 369, 411-414.
-
(1994)
Nature
, vol.369
, pp. 411-414
-
-
Leevers, S.J.1
Paterson, H.F.2
Marshall, C.J.3
|