Transcriptional induction of cyclooxygenase-2 gene by okadaic acid inhibition of phosphatase activity in human chondrocytes: Co-stimulation of AP-1 and CRE nuclear binding proteins

Journal of Cellular Biochemistry

Volumn 69, Issue 4, 1998, Pages 392-413

  Miller, Caroline ^a   Zhang, Mengkun ^a,b   He, Yulan ^b   Zhao, Jie ^c,d   Pelletier, Jean Pierre ^b   Martel Pelletier, Johanne ^b   Di Battista, John A ^b  

^a UNIVERSITÉ DE MONTRÉAL   (Canada)

^b NOTRE DAME HOSPITAL   (Canada)

^c MCGILL UNIVERSITY   (Canada)

^d MCGILL UNIVERSITY   (Canada)

Author keywords

c Jun N terminal kinase; cAMP response element; Chondrocytes; Cyclooxygenase 2; Protein kinase A

Indexed keywords

CALPHOSTIN C; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; CYCLOOXYGENASE 2; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 6; KT 5720; MITOGEN ACTIVATED PROTEIN KINASE; OKADAIC ACID; OLIGONUCLEOTIDE; PHOSPHOPROTEIN PHOSPHATASE 1; PHOSPHOPROTEIN PHOSPHATASE 2A; PROTEIN KINASE C; TRANSCRIPTION FACTOR AP 1; TRANSCRIPTION FACTOR SP1;

ARTICLE; CARTILAGE CELL; CONTROLLED STUDY; CYCLIC AMP RESPONSIVE ELEMENT; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME SYNTHESIS; GENE EXPRESSION; GENE INDUCTION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN PHOSPHORYLATION; PROTO ONCOGENE; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION;

ANTIOXIDANTS; CA(2+)-CALMODULIN DEPENDENT PROTEIN KINASE; CELLS, CULTURED; CHONDROCYTES; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; CYCLIC AMP-DEPENDENT PROTEIN KINASES; CYCLOOXYGENASE 2; DNA; ENZYME INDUCTION; ENZYME INHIBITORS; HUMANS; ISOENZYMES; MEMBRANE PROTEINS; OKADAIC ACID; PHOSPHOPROTEIN PHOSPHATASE; PHOSPHORYLATION; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES; PROTEIN KINASE C; PROTO-ONCOGENES; PYRROLIDINES; RECOMBINANT FUSION PROTEINS; RNA, MESSENGER; SIGNAL TRANSDUCTION; THIOCARBAMATES; TRANS-ACTIVATION (GENETICS); TRANSCRIPTION FACTOR AP-1;

EID: 0031779836     PISSN: 07302312     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-4644(19980615)69:4<392::AID-JCB2>3.0.CO;2-I     Document Type: Article

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