Rac2D57N, a dominant inhibitory Rac2 mutant that inhibits p38 kinase signaling and prevents surface ruffling in bone-marrow-derived macrophages

Journal of Cell Science

Volumn 117, Issue 2, 2004, Pages 243-255

  Abell, Amy N ^a,d   DeCathelineau, Aimee M ^c   Weed, Scott A ^a   Ambruso, Daniel R ^b   Riches, David W ^c   Johnson, Gary L ^a,d  

^a UNIVERSITY OF COLORADO   (United States)

^b Children's Hospital Colorado   (United States)

^c NATIONAL JEWISH MEDICAL AND RESEARCH CENTER   (United States)

^d UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

Author keywords

Actin; Bone marrow derived macrophage; Human mutation; p38 kinase; Rac2

Indexed keywords

ACTIN; ASPARAGINE; ASPARTIC ACID; GUANINE NUCLEOTIDE; GUANOSINE DIPHOSPHATE; GUANOSINE TRIPHOSPHATE; LIPOPOLYSACCHARIDE; MITOGEN ACTIVATED PROTEIN KINASE P38; RAC1 PROTEIN; RECOMBINANT ENZYME; RHO GUANINE NUCLEOTIDE BINDING PROTEIN; GUANINE NUCLEOTIDE EXCHANGE FACTOR; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN; RAC PROTEIN; RAC2 PROTEIN; TIAM1 PROTEIN, MOUSE;

ACTIN FILAMENT; ALLELE; AMINO ACID SUBSTITUTION; ANIMAL CELL; ARTICLE; BACTERIAL INFECTION; BINDING AFFINITY; CELL SURFACE; CONTROLLED STUDY; DISEASE SEVERITY; ENZYME ACTIVATION; IMMUNE DEFICIENCY; IMMUNOPRECIPITATION; MACROPHAGE; MICROTUBULE; NEUTROPHIL; NONHUMAN; PINOCYTOSIS; POINT MUTATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; ANIMAL; BONE MARROW; CELL SIZE; CELL STRAIN COS1; CERCOPITHECUS; CYTOSKELETON; ENZYME INDUCTION; FLUORESCENCE MICROSCOPY; GENETICS; METABOLISM; MOUSE; MUTATION; PROTEIN BINDING;

ANIMALIA; BACTERIA (MICROORGANISMS); MURINAE;

ACTINS; ANIMALS; BONE MARROW; CELL SIZE; CELL SURFACE EXTENSIONS; CERCOPITHECUS AETHIOPS; COS CELLS; CYTOSKELETON; ENZYME INDUCTION; GUANINE NUCLEOTIDE EXCHANGE FACTORS; GUANINE NUCLEOTIDES; MACROPHAGES; MICE; MICROSCOPY, FLUORESCENCE; MICROTUBULES; MITOGEN-ACTIVATED PROTEIN KINASES; MUTATION; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PROTEIN BINDING; PROTEINS; RAC GTP-BINDING PROTEINS; RAC1 GTP-BINDING PROTEIN;

EID: 1642462398     PISSN: 00219533     EISSN: None     Source Type: Journal    
DOI: 10.1242/jcs.00853     Document Type: Article

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