메뉴 건너뛰기




Volumn 20, Issue 1, 2004, Pages 37-44

The nucleolus: Functions, assembly and pathology;Le nucléole: Structure, fonctions et maladies associées

Author keywords

[No Author keywords available]

Indexed keywords

NUCLEAR PROTEIN;

EID: 1642419805     PISSN: 07670974     EISSN: None     Source Type: Journal    
DOI: 10.1051/medsci/200420137     Document Type: Review
Times cited : (17)

References (52)
  • 3
    • 0033153298 scopus 로고    scopus 로고
    • Structure and function of the nucleolus
    • Scheer U, Hock R. Structure and function of the nucleolus. Curr Opin Cell Biol 1999; 11: 385-90.
    • (1999) Curr Opin Cell Biol , vol.11 , pp. 385-390
    • Scheer, U.1    Hock, R.2
  • 4
    • 0033258081 scopus 로고    scopus 로고
    • The nucleolus: A paradigm for cell proliferation and aging
    • Comai L. The nucleolus: a paradigm for cell proliferation and aging. Braz J Med Biol Res 1999; 32: 1473-8.
    • (1999) Braz J Med Biol Res , vol.32 , pp. 1473-1478
    • Comai, L.1
  • 5
    • 0032169650 scopus 로고    scopus 로고
    • The plurifunctional nucleolus
    • Pederson T. The plurifunctional nucleolus. Nucleic Acids Res 1998; 26: 3871-6.
    • (1998) Nucleic Acids Res , vol.26 , pp. 3871-3876
    • Pederson, T.1
  • 6
    • 0034098784 scopus 로고    scopus 로고
    • The nucleolus: The magician's hat for cell cycle tricks
    • Visintin R, Amon A. The nucleolus: the magician's hat for cell cycle tricks. Curr Opin Cell Biol 2000; 12: 372-7.
    • (2000) Curr Opin Cell Biol , vol.12 , pp. 372-377
    • Visintin, R.1    Amon, A.2
  • 7
    • 0037039159 scopus 로고    scopus 로고
    • Directed proteomic analysis of the human nucleolus
    • Andersen JS, Lyon CE, Fox AH, et al. Directed proteomic analysis of the human nucleolus. Curr Biol 2002; 12: 1-11.
    • (2002) Curr Biol , vol.12 , pp. 1-11
    • Andersen, J.S.1    Lyon, C.E.2    Fox, A.H.3
  • 8
    • 0037071545 scopus 로고    scopus 로고
    • In vivo analysis of NHPX reveals a novel nucleolar localization pathway involving a transient accumulation in splicing speckles
    • Leung AK, Lamond AI. In vivo analysis of NHPX reveals a novel nucleolar localization pathway involving a transient accumulation in splicing speckles. J Cell Biol 2002; 157: 615-29.
    • (2002) J Cell Biol , vol.157 , pp. 615-629
    • Leung, A.K.1    Lamond, A.I.2
  • 9
    • 0037039475 scopus 로고    scopus 로고
    • Paraspeckles: A novel nuclear domain
    • Fox AH, Lam YW, Leung AKL, et al. Paraspeckles: a novel nuclear domain. Curr Biol 2002; 12: 13-25.
    • (2002) Curr Biol , vol.12 , pp. 13-25
    • Fox, A.H.1    Lam, Y.W.2    Leung, A.K.L.3
  • 10
    • 0035316574 scopus 로고    scopus 로고
    • Chromosome territories, nuclear architecture and gene regulation in mammalian cells
    • Cremer T, Cremer C. Chromosome territories, nuclear architecture and gene regulation in mammalian cells. Nat Rev Genet 2001; 2: 292-301.
    • (2001) Nat Rev Genet , vol.2 , pp. 292-301
    • Cremer, T.1    Cremer, C.2
  • 11
    • 0029791261 scopus 로고    scopus 로고
    • Functional compartmentalization of the nucleus
    • Strouboulis J, Wolffe AP. Functional compartmentalization of the nucleus. J Cell Sci 1996; 109: 1991-2000.
    • (1996) J Cell Sci , vol.109 , pp. 1991-2000
    • Strouboulis, J.1    Wolffe, A.P.2
  • 12
    • 0029055194 scopus 로고
    • The nucleolus: An organelle formed by the act of building a ribosome
    • Mélèse T, Xue Z. The nucleolus: an organelle formed by the act of building a ribosome. Curr Opin Cell Biol 1995; 7: 319-24.
    • (1995) Curr Opin Cell Biol , vol.7 , pp. 319-324
    • Mélèse, T.1    Xue, Z.2
  • 13
    • 0343081680 scopus 로고    scopus 로고
    • Assembly and functional organization of the nucleolus: Ultrastructural analysis of Saccharomyces cerevisiae mutants
    • Trumtel S, Léger-Silvestre I, Giezes PE, Teulières F, Gas N. Assembly and functional organization of the nucleolus: ultrastructural analysis of Saccharomyces cerevisiae mutants. Mol Biol Cell 2000; 11: 2175-89.
    • (2000) Mol Biol Cell , vol.11 , pp. 2175-2189
    • Trumtel, S.1    Léger-Silvestre, I.2    Giezes, P.E.3    Teulières, F.4    Gas, N.5
  • 14
    • 0024392359 scopus 로고
    • Two different chromatin structures coexist in ribosomal RNA genes throughout the cell cycle
    • Conconi A, Widmer RM, Koller T, Sogo JM. Two different chromatin structures coexist in ribosomal RNA genes throughout the cell cycle. Cell 1989; 57: 753-61.
    • (1989) Cell , vol.57 , pp. 753-761
    • Conconi, A.1    Widmer, R.M.2    Koller, T.3    Sogo, J.M.4
  • 15
    • 0027270476 scopus 로고
    • Chromatin structures and transcription of rDNA in yeast Saccharomyces cerevisiae
    • Dommann R, Lucchini R, Koller T, Sogo JM. Chromatin structures and transcription of rDNA in yeast Saccharomyces cerevisiae. Nucleic Acids Res 1993; 21: 2331-8.
    • (1993) Nucleic Acids Res , vol.21 , pp. 2331-2338
    • Dommann, R.1    Lucchini, R.2    Koller, T.3    Sogo, J.M.4
  • 16
    • 17944383329 scopus 로고    scopus 로고
    • Net1 stimulates RNA polymerase I transcription and regulates nucleolar structure independently of controlling mitotic exit
    • Shou W, Sakomoto KM, Keener J, et al. Net1 stimulates RNA polymerase I transcription and regulates nucleolar structure independently of controlling mitotic exit. Mol Cell 2001; 8: 45-55.
    • (2001) Mol Cell , vol.8 , pp. 45-55
    • Shou, W.1    Sakomoto, K.M.2    Keener, J.3
  • 17
    • 0029112540 scopus 로고
    • Transcription in the yeast rRNA gene locus: Distribution of the active gene copies and chromatin structure of their flanking regulatory sequences
    • Dammann R, Lucchini R, Koller T, Sogo JM. Transcription in the yeast rRNA gene locus: distribution of the active gene copies and chromatin structure of their flanking regulatory sequences. Mol Cell Biol 1995; 15: 5294-303.
    • (1995) Mol Cell Biol , vol.15 , pp. 5294-5303
    • Dammann, R.1    Lucchini, R.2    Koller, T.3    Sogo, J.M.4
  • 18
    • 1842336265 scopus 로고    scopus 로고
    • Involvement of in situ conformation of ribosomal genes and selective distribution of UBF in rRNA transcription
    • Junéra HR, Masson C, Géraud G, Suja J, Hernandez-Verdun D. Involvement of in situ conformation of ribosomal genes and selective distribution of UBF in rRNA transcription. Mol Biol Cell 1997; 8: 145-56.
    • (1997) Mol Biol Cell , vol.8 , pp. 145-156
    • Junéra, H.R.1    Masson, C.2    Géraud, G.3    Suja, J.4    Hernandez-Verdun, D.5
  • 19
    • 0000654017 scopus 로고    scopus 로고
    • When rDNA transcription is arrested during mitosis, UBF is still associated with non-condensed rDNA
    • Gébrane-Younès J, Fomproix N, Hernandez-Verdun D. When rDNA transcription is arrested during mitosis, UBF is still associated with non-condensed rDNA. J Cell Sci 1997; 110: 2429-40.
    • (1997) J Cell Sci , vol.110 , pp. 2429-2440
    • Gébrane-Younès, J.1    Fomproix, N.2    Hernandez-Verdun, D.3
  • 20
    • 0032618597 scopus 로고    scopus 로고
    • Regulation of mammalian ribosomal gene transcription by RNA polymerase I
    • Grummt I. Regulation of mammalian ribosomal gene transcription by RNA polymerase I. Prog Nucleic Acids Res Mol Biol 1999; 62: 109-54.
    • (1999) Prog Nucleic Acids Res Mol Biol , vol.62 , pp. 109-154
    • Grummt, I.1
  • 21
    • 0037013144 scopus 로고    scopus 로고
    • TFIIH Mill plays on essential role in RNA polymerase I transcription
    • Iben S, Tschochner H, Bier M, et al. TFIIH Mill plays on essential role in RNA polymerase I transcription. Cell 2002; 109: 297-306.
    • (2002) Cell , vol.109 , pp. 297-306
    • Iben, S.1    Tschochner, H.2    Bier, M.3
  • 22
    • 0033367325 scopus 로고    scopus 로고
    • Ribosome synthesis in Saccharomyces cerevisiae
    • Venema J, Tollervey D. Ribosome synthesis in Saccharomyces cerevisiae. Annu Rev Genet 1999; 33: 261-311.
    • (1999) Annu Rev Genet , vol.33 , pp. 261-311
    • Venema, J.1    Tollervey, D.2
  • 23
    • 0036591884 scopus 로고    scopus 로고
    • Biogenesis of small nucleolar robonucleoproteins
    • Filipowicz W, Pogacic V. Biogenesis of small nucleolar robonucleoproteins. Curr Opin Cell Biol 2002; 14: 319-27.
    • (2002) Curr Opin Cell Biol , vol.14 , pp. 319-327
    • Filipowicz, W.1    Pogacic, V.2
  • 24
    • 0029939247 scopus 로고    scopus 로고
    • The 3' end of the yeast 5.8 rRNA is generated by an exonuclease processing mechanism
    • Mitchell P, Petfalski E, Tollervey D. The 3' end of the yeast 5.8 rRNA is generated by an exonuclease processing mechanism. Genes Dev 1996; 10: 502-13.
    • (1996) Genes Dev , vol.10 , pp. 502-513
    • Mitchell, P.1    Petfalski, E.2    Tollervey, D.3
  • 25
    • 0034857262 scopus 로고    scopus 로고
    • DExD/H box RNA helicases: From generic motors to specific dissociation functions
    • Tanner K, Linder P. DExD/H box RNA helicases: from generic motors to specific dissociation functions. Mol Cell 2001; 8: 251-62.
    • (2001) Mol Cell , vol.8 , pp. 251-262
    • Tanner, K.1    Linder, P.2
  • 27
    • 17944367764 scopus 로고    scopus 로고
    • Composition and functional characterization of yeast 66S ribosome assembly intermediates
    • Harnpicharnchai P, Jakovljevic J, Horsey E, et al. Composition and functional characterization of yeast 66S ribosome assembly intermediates. Mol Cell 2001; 8: 505-15.
    • (2001) Mol Cell , vol.8 , pp. 505-515
    • Harnpicharnchai, P.1    Jakovljevic, J.2    Horsey, E.3
  • 28
    • 0032562647 scopus 로고    scopus 로고
    • The role of the 3' external transcribed spacer in yeast pre-rRNA processing
    • Allmang C, Tollervey D. The role of the 3' external transcribed spacer in yeast pre-rRNA processing. J Mol Biol 1998; 278: 67-78.
    • (1998) J Mol Biol , vol.278 , pp. 67-78
    • Allmang, C.1    Tollervey, D.2
  • 29
    • 0037128933 scopus 로고    scopus 로고
    • Cyclin-dependent kinases govern formation and maintenance of the nucleolus
    • Sirri V, Hernandez-Verdun D, Roussel P. Cyclin-dependent kinases govern formation and maintenance of the nucleolus. J Cell Biol 2002; 156: 969-81.
    • (2002) J Cell Biol , vol.156 , pp. 969-981
    • Sirri, V.1    Hernandez-Verdun, D.2    Roussel, P.3
  • 30
    • 0026665603 scopus 로고
    • Alterations of nueleolar ultrastructure and ribosome biogenesis by actinomycin D. Implications for U3 snRNP function
    • Puvion-Dutilleu F, Mazan S, Nicoloso M, Pichard E, Bachellerie P, Puvion E. Alterations of nueleolar ultrastructure and ribosome biogenesis by actinomycin D. Implications for U3 snRNP function. Eur J Cell Biol 1992; 58: 149-62.
    • (1992) Eur J Cell Biol , vol.58 , pp. 149-162
    • Puvion-Dutilleu, F.1    Mazan, S.2    Nicoloso, M.3    Pichard, E.4    Bachellerie, P.5    Puvion, E.6
  • 31
    • 0030738274 scopus 로고    scopus 로고
    • Early stages of pre-rRNA formation within the nucleolar ultrastructure of mouse cells studied by in situ hybridization with 5'ETS leader probe
    • Puvion-Dutilleu F, Puvion E, Bachellerie JP. Early stages of pre-rRNA formation within the nucleolar ultrastructure of mouse cells studied by in situ hybridization with 5'ETS leader probe. Chromosoma 1997; 105: 496-505.
    • (1997) Chromosoma , vol.105 , pp. 496-505
    • Puvion-Dutilleu, F.1    Puvion, E.2    Bachellerie, J.P.3
  • 33
    • 0032866533 scopus 로고    scopus 로고
    • 3-D organization of single ribosomal transcription units after DRB inhibition of RNA polymerase II transcription
    • Le Panse S, Masson C, Héliot L, Chassery JM, Junéra HR, Hernandez-Verdun D. 3-D organization of single ribosomal transcription units after DRB inhibition of RNA polymerase II transcription. J Cell Sci 1999; 112: 2145-54.
    • (1999) J Cell Sci , vol.112 , pp. 2145-2154
    • Le Panse, S.1    Masson, C.2    Héliot, L.3    Chassery, J.M.4    Junéra, H.R.5    Hernandez-Verdun, D.6
  • 34
    • 0030005052 scopus 로고    scopus 로고
    • Inhibition of RNA polymerase II transcription causes chromatin decondensation, loss of nucleolar structure, and dispersion of chromosomal domains
    • Haaf T, Ward DC. Inhibition of RNA polymerase II transcription causes chromatin decondensation, loss of nucleolar structure, and dispersion of chromosomal domains. Exp Cell Res 1996; 224: 163-73.
    • (1996) Exp Cell Res , vol.224 , pp. 163-173
    • Haaf, T.1    Ward, D.C.2
  • 35
    • 0030006048 scopus 로고    scopus 로고
    • The rDNA transcription machinery is assembled during mitosis in active NORs and absent in inactive NORs
    • Roussel P, André C, Comai L, Hernandez-Verdun D. The rDNA transcription machinery is assembled during mitosis in active NORs and absent in inactive NORs. J Cell Biol 1996; 133: 235-46.
    • (1996) J Cell Biol , vol.133 , pp. 235-246
    • Roussel, P.1    André, C.2    Comai, L.3    Hernandez-Verdun, D.4
  • 36
    • 0032703098 scopus 로고    scopus 로고
    • The mitotically phosphorylated form of the transcription termination factor TTF-1 is associated with the repressed rDNA transcription machinery
    • Sirri V, Roussel P, Hernandez-Verdun D. The mitotically phosphorylated form of the transcription termination factor TTF-1 is associated with the repressed rDNA transcription machinery. J Cell Sci 1999; 112: 3259-68.
    • (1999) J Cell Sci , vol.112 , pp. 3259-3268
    • Sirri, V.1    Roussel, P.2    Hernandez-Verdun, D.3
  • 37
    • 0034707645 scopus 로고    scopus 로고
    • In vivo release of mitotic silencing of ribosomal gene transcription does not give rise to precursor ribosomal RNA processing
    • Sirri V, Roussel P, Hernandez-Verdun D. In vivo release of mitotic silencing of ribosomal gene transcription does not give rise to precursor ribosomal RNA processing. J Cell Biol 2000; 148: 259-70.
    • (2000) J Cell Biol , vol.148 , pp. 259-270
    • Sirri, V.1    Roussel, P.2    Hernandez-Verdun, D.3
  • 38
    • 14444283146 scopus 로고    scopus 로고
    • Presence of pre-rRNAs before activation of polymerase I transcription in the building process of nucleoli during early development of Xenopus laevis
    • Verheggen C, Le Panse S, Almouzni G, Hernandez-Verdun D. Presence of pre-rRNAs before activation of polymerase I transcription in the building process of nucleoli during early development of Xenopus laevis. J Cell Biol 1998; 142: 1167-80.
    • (1998) J Cell Biol , vol.142 , pp. 1167-1180
    • Verheggen, C.1    Le Panse, S.2    Almouzni, G.3    Hernandez-Verdun, D.4
  • 39
    • 0034678358 scopus 로고    scopus 로고
    • The ribosomal RNA processing machinery is recruited to the nucleolar domain before RNA polymerase I during Xenopus laevis development
    • Verheggen C, Almouzni G, Hernandez-Verdun D. The ribosomal RNA processing machinery is recruited to the nucleolar domain before RNA polymerase I during Xenopus laevis development. J Cell Biol 2000; 149: 293-305.
    • (2000) J Cell Biol , vol.149 , pp. 293-305
    • Verheggen, C.1    Almouzni, G.2    Hernandez-Verdun, D.3
  • 40
    • 0033118941 scopus 로고    scopus 로고
    • Phosphorylation by G1-specific cdk-cyclin complexes activates the nucleolar transcription factor UBF
    • Voit R, Hoffmann M, Grummt I. Phosphorylation by G1-specific cdk-cyclin complexes activates the nucleolar transcription factor UBF. EMBO J 1999; 18: 1891-9.
    • (1999) EMBO J , vol.18 , pp. 1891-1899
    • Voit, R.1    Hoffmann, M.2    Grummt, I.3
  • 41
    • 0035079628 scopus 로고    scopus 로고
    • A step subsequent to preinitiation complex assembly at the ribosomal RNA gene promoter is rate limiting for human RNA polymerase I-dependent transcription
    • Panov KI, Friedrich JK, Zomerdijk JCBM. A step subsequent to preinitiation complex assembly at the ribosomal RNA gene promoter is rate limiting for human RNA polymerase I-dependent transcription. Mol Cell Biol 2001; 21: 2641-9.
    • (2001) Mol Cell Biol , vol.21 , pp. 2641-2649
    • Panov, K.I.1    Friedrich, J.K.2    Zomerdijk, J.C.B.M.3
  • 43
    • 0035921777 scopus 로고    scopus 로고
    • Common and reversible regulation of wild-type p53 function and of ribosomal biogenesis by protein kinases in human cells
    • David-Pfeuty T, Nouvian-Dooghe Y, Sirri V, Roussel P, Hernandez-Verdun D. Common and reversible regulation of wild-type p53 function and of ribosomal biogenesis by protein kinases in human cells. Oncogene 2001; 20: 5951-63.
    • (2001) Oncogene , vol.20 , pp. 5951-5963
    • David-Pfeuty, T.1    Nouvian-Dooghe, Y.2    Sirri, V.3    Roussel, P.4    Hernandez-Verdun, D.5
  • 44
    • 0034977001 scopus 로고    scopus 로고
    • Evidence of p53-dependent cross-talk between ribosome biogenesis and cell cycle: Effects of nucleolar protein Bop1 on G1/5 transition
    • Pestov DG, Strezoska Z, Lau LF. Evidence of p53-dependent cross-talk between ribosome biogenesis and cell cycle: effects of nucleolar protein Bop1 on G1/5 transition. Mol Cell Biol 2001; 21: 4246-55.
    • (2001) Mol Cell Biol , vol.21 , pp. 4246-4255
    • Pestov, D.G.1    Strezoska, Z.2    Lau, L.F.3
  • 46
    • 0030820491 scopus 로고    scopus 로고
    • Accelerated aging and nucleolar fragmentation in yeast sgs1 mutants
    • Sinclair DA, Mills K, Guarente I. Accelerated aging and nucleolar fragmentation in yeast sgs1 mutants. Science 1997; 277: 1313-6.
    • (1997) Science , vol.277 , pp. 1313-1316
    • Sinclair, D.A.1    Mills, K.2    Guarente, I.3
  • 47
    • 85047699548 scopus 로고    scopus 로고
    • WRN helicase accelarates the transcription of ribosomal RNA as a component of an RNA polymerase I-associated complex
    • Shiratori M, Suzuki T, Itoh C, Goto M, Furuichi Y, Matsumoto T. WRN helicase accelarates the transcription of ribosomal RNA as a component of an RNA polymerase I-associated complex. Oncogene 2002; 21: 2447-54.
    • (2002) Oncogene , vol.21 , pp. 2447-2454
    • Shiratori, M.1    Suzuki, T.2    Itoh, C.3    Goto, M.4    Furuichi, Y.5    Matsumoto, T.6
  • 48
    • 0030903167 scopus 로고    scopus 로고
    • Identification of the complete coding requence and genomic organization of the Treacher Collins syndrome gene
    • Dixon J, Edwards SJ, Anderson I, Brass A, Scambler PJ, Dixon MJ. Identification of the complete coding requence and genomic organization of the Treacher Collins syndrome gene. Genome Res 1997; 7: 223-34.
    • (1997) Genome Res , vol.7 , pp. 223-234
    • Dixon, J.1    Edwards, S.J.2    Anderson, I.3    Brass, A.4    Scambler, P.J.5    Dixon, M.J.6
  • 49
    • 0034494767 scopus 로고    scopus 로고
    • Characterization of the nucleolar gene product, treacle, in Treacher Collins syndrome
    • Isaac C, Marsh KL, Paznekas WA, et al. Characterization of the nucleolar gene product, treacle, in Treacher Collins syndrome. Mol Biol Cell 2000; 11: 3061-71.
    • (2000) Mol Biol Cell , vol.11 , pp. 3061-3071
    • Isaac, C.1    Marsh, K.L.2    Paznekas, W.A.3
  • 50
    • 0035253526 scopus 로고    scopus 로고
    • Stable expression in yeast of the mature form of human telomerase RNA depends on its association with the box H/ACA small nucleolar RNP proteins Cbf5p, Nhp2p and Nop10p
    • Dez C, Henras A, Faucon B, Lafontaine D, Caizergues-Ferrer M, Henry Y. Stable expression in yeast of the mature form of human telomerase RNA depends on its association with the box H/ACA small nucleolar RNP proteins Cbf5p, Nhp2p and Nop10p. Nucleic Acids Res 2001; 29: 598-603.
    • (2001) Nucleic Acids Res , vol.29 , pp. 598-603
    • Dez, C.1    Henras, A.2    Faucon, B.3    Lafontaine, D.4    Caizergues-Ferrer, M.5    Henry, Y.6
  • 52
    • 0342669896 scopus 로고    scopus 로고
    • TTF-1 determines the chromatin architecture of the active rDNA promoter
    • Längst G, Becker PB, Grummt I. TTF-1 determines the chromatin architecture of the active rDNA promoter. EMBO J 1998; 17: 3135-43.
    • (1998) EMBO J , vol.17 , pp. 3135-3143
    • Längst, G.1    Becker, P.B.2    Grummt, I.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.