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Volumn 34, Issue 3, 2004, Pages 806-816

The RhoA- and CDC42-specific exchange factor Dbs promotes expansion of immature thymocytes and deletion of double-positive and single-positive thymocytes

Author keywords

Rho GTPases; Thymocyte development

Indexed keywords

GUANINE NUCLEOTIDE EXCHANGE FACTOR; GUANINE NUCLEOTIDE EXCHANGE FACTOR DBS; MONOCLONAL ANTIBODY CD3; PROTEIN CDC42; RHO GUANINE NUCLEOTIDE BINDING PROTEIN; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; T LYMPHOCYTE RECEPTOR; UNCLASSIFIED DRUG; LYMPHOCYTE ANTIGEN RECEPTOR; MCF2L PROTEIN, MOUSE;

EID: 1642368421     PISSN: 00142980     EISSN: None     Source Type: Journal    
DOI: 10.1002/eji.200324400     Document Type: Article
Times cited : (5)

References (44)
  • 1
    • 0035313978 scopus 로고    scopus 로고
    • Signal strength in thymic selection and lineage commitment
    • Hogquist, K. A., Signal strength in thymic selection and lineage commitment. Curr. Opin. Immunol. 2001. 13: 225-231.
    • (2001) Curr. Opin. Immunol. , vol.13 , pp. 225-231
    • Hogquist, K.A.1
  • 4
    • 0034618566 scopus 로고    scopus 로고
    • T cell lineage fate: Instructed by receptor signals?
    • von Boehmer, H., T cell lineage fate: instructed by receptor signals? Curr. Biol. 2000. 10: R642-R645.
    • (2000) Curr. Biol. , vol.10
    • von Boehmer, H.1
  • 5
    • 0035236095 scopus 로고    scopus 로고
    • The Goldilocks conditions applied to T cell development
    • Yun, T. J. and Bevan, M. J., The Goldilocks conditions applied to T cell development. Nat. Immunol. 2001. 2: 13-14.
    • (2001) Nat. Immunol. , vol.2 , pp. 13-14
    • Yun, T.J.1    Bevan, M.J.2
  • 6
    • 0035366079 scopus 로고    scopus 로고
    • MAP-kinase signaling pathways in T cells
    • Rincon, M., MAP-kinase signaling pathways in T cells. Curr. Opin. Immunol. 2001. 13: 339-345.
    • (2001) Curr. Opin. Immunol. , vol.13 , pp. 339-345
    • Rincon, M.1
  • 7
    • 0035313993 scopus 로고    scopus 로고
    • Molecular determinants of TCR expression and selection
    • Berg, L. J. and Kang, J., Molecular determinants of TCR expression and selection. Curr. Opin. Immunol. 2001. 13: 232-241.
    • (2001) Curr. Opin. Immunol. , vol.13 , pp. 232-241
    • Berg, L.J.1    Kang, J.2
  • 8
    • 0036225712 scopus 로고    scopus 로고
    • T cell antigen receptor signal transduction
    • Cantrell, D. A., T cell antigen receptor signal transduction. Immunology 2002. 105: 369-374.
    • (2002) Immunology , vol.105 , pp. 369-374
    • Cantrell, D.A.1
  • 9
    • 0032055502 scopus 로고    scopus 로고
    • Networking Rho family GTPases in lymphocytes
    • Reif, K. and Cantrell, D. A., Networking Rho family GTPases in lymphocytes. Immunity 1998. 8: 395-401.
    • (1998) Immunity , vol.8 , pp. 395-401
    • Reif, K.1    Cantrell, D.A.2
  • 10
    • 0037069690 scopus 로고    scopus 로고
    • Rho GTPases in cell biology
    • Etienne-Manneville, S. and Hall, A., Rho GTPases in cell biology. Nature 2002. 420: 629-635.
    • (2002) Nature , vol.420 , pp. 629-635
    • Etienne-Manneville, S.1    Hall, A.2
  • 11
    • 0035996796 scopus 로고    scopus 로고
    • Understanding Rho/Rac biology in T cells using animal models
    • Bustelo, X. R., Understanding Rho/Rac biology in T cells using animal models. Bioessays 2002. 24: 602-612.
    • (2002) Bioessays , vol.24 , pp. 602-612
    • Bustelo, X.R.1
  • 12
    • 0036359608 scopus 로고    scopus 로고
    • Transgenic analysis of thymocyte signal transduction
    • Cantrell, D. A., Transgenic analysis of thymocyte signal transduction. Nat. Rev. Immunol. 2002. 2: 20-27.
    • (2002) Nat. Rev. Immunol. , vol.2 , pp. 20-27
    • Cantrell, D.A.1
  • 13
    • 0030946814 scopus 로고    scopus 로고
    • The GTPase Rho has a critical regulatory role in thymus development
    • Henning, S. W., Galandrini, R., Hall, A. and Cantrell, D. A., The GTPase Rho has a critical regulatory role in thymus development. EMBO J. 1997. 16: 2397-2407.
    • (1997) EMBO J. , vol.16 , pp. 2397-2407
    • Henning, S.W.1    Galandrini, R.2    Hall, A.3    Cantrell, D.A.4
  • 14
    • 0030806477 scopus 로고    scopus 로고
    • Different functions of the GTPase Rho in prothymocytes and late pre-T cells
    • Galandrini, R., Henning, S. W. and Cantrell, D. A., Different functions of the GTPase Rho in prothymocytes and late pre-T cells. Immunity 1997. 7: 163-174.
    • (1997) Immunity , vol.7 , pp. 163-174
    • Galandrini, R.1    Henning, S.W.2    Cantrell, D.A.3
  • 15
    • 0033578019 scopus 로고    scopus 로고
    • Inhibition of Rho at different stages of thymocyte development gives different perspectives on Rho function
    • Cleverley, S., Henning, S. and Cantrell, D., Inhibition of Rho at different stages of thymocyte development gives different perspectives on Rho function. Curr. Biol. 1999. 9: 657-660.
    • (1999) Curr. Biol. , vol.9 , pp. 657-660
    • Cleverley, S.1    Henning, S.2    Cantrell, D.3
  • 17
    • 0032494156 scopus 로고    scopus 로고
    • p56lck signals for regulating thymocyte development can be distinguished by their dependency on Rho function
    • Henning, S. W. and Cantrell, D. A., p56lck signals for regulating thymocyte development can be distinguished by their dependency on Rho function. J. Exp. Med. 1998. 188: 931-939.
    • (1998) J. Exp. Med. , vol.188 , pp. 931-939
    • Henning, S.W.1    Cantrell, D.A.2
  • 18
    • 0035476474 scopus 로고    scopus 로고
    • Analysis of thymocyte development reveals that the GTPase RhoA is a positive regulator of T cell receptor responses in vivo
    • Corre, I., Gomez, M., Vielkind, S. and Cantrell, D. A., Analysis of thymocyte development reveals that the GTPase RhoA is a positive regulator of T cell receptor responses in vivo. J. Exp. Med. 2001. 194: 903-914.
    • (2001) J. Exp. Med. , vol.194 , pp. 903-914
    • Corre, I.1    Gomez, M.2    Vielkind, S.3    Cantrell, D.A.4
  • 19
    • 0034305495 scopus 로고    scopus 로고
    • Control of pre-T cell proliferation and differentiation by the GTPase Rac-I
    • Gomez, M., Tybulewicz, V. and Cantrell, D. A., Control of pre-T cell proliferation and differentiation by the GTPase Rac-I. Nat. Immunol. 2000. 1: 348-352.
    • (2000) Nat. Immunol. , vol.1 , pp. 348-352
    • Gomez, M.1    Tybulewicz, V.2    Cantrell, D.A.3
  • 20
    • 0033598932 scopus 로고    scopus 로고
    • Expression of activated CDC42 induces T cell apoptosis in thymus and peripheral lymph organs via different pathways
    • Na, S., Li, B., Grewal, I. S., Enslen, H., Davis, R. J., Hanke, J. H. and Flavell, R. A., Expression of activated CDC42 induces T cell apoptosis in thymus and peripheral lymph organs via different pathways. Oncogene 1999. 18: 7966-7974.
    • (1999) Oncogene , vol.18 , pp. 7966-7974
    • Na, S.1    Li, B.2    Grewal, I.S.3    Enslen, H.4    Davis, R.J.5    Hanke, J.H.6    Flavell, R.A.7
  • 21
    • 0035652283 scopus 로고    scopus 로고
    • The GTPase Rac-1 controls cell fate in the thymus by diverting thymocytes from positive to negative selection
    • Gomez, M., Kioussis, D. and Cantrell, D. A., The GTPase Rac-1 controls cell fate in the thymus by diverting thymocytes from positive to negative selection. Immunity 2001. 15: 703-713.
    • (2001) Immunity , vol.15 , pp. 703-713
    • Gomez, M.1    Kioussis, D.2    Cantrell, D.A.3
  • 22
    • 0030772153 scopus 로고    scopus 로고
    • Enhanced apoptosis in the thymus of transgenic mice expressing constitutively activated forms of human Rac2GTPase
    • Lores, P., Morin, L., Luna, R. and Gacon, G., Enhanced apoptosis in the thymus of transgenic mice expressing constitutively activated forms of human Rac2GTPase. Oncogene 1997. 15: 601-605.
    • (1997) Oncogene , vol.15 , pp. 601-605
    • Lores, P.1    Morin, L.2    Luna, R.3    Gacon, G.4
  • 24
    • 0032191837 scopus 로고    scopus 로고
    • Differential roles of ERK and p38 MAP kinase pathways in positive and negative selection of T lymphocytes
    • Sugawara, T., Moriguchi, T., Nishida, E. and Takahama, Y., Differential roles of ERK and p38 MAP kinase pathways in positive and negative selection of T lymphocytes. Immunity 1998. 9: 565-574.
    • (1998) Immunity , vol.9 , pp. 565-574
    • Sugawara, T.1    Moriguchi, T.2    Nishida, E.3    Takahama, Y.4
  • 25
    • 0028948329 scopus 로고
    • Retroviral transduction and oncogenic selection of a cDNA encoding Dbs, a homolog of the Dbl guanine nucleotide exchange factor
    • Whitehead, I., Kirk, H. and Kay, R., Retroviral transduction and oncogenic selection of a cDNA encoding Dbs, a homolog of the Dbl guanine nucleotide exchange factor. Oncogene 1995. 10: 713-721.
    • (1995) Oncogene , vol.10 , pp. 713-721
    • Whitehead, I.1    Kirk, H.2    Kay, R.3
  • 28
    • 0028110120 scopus 로고
    • A novel oncogene, Ost, encodes a guanine nucleotide exchange factor that potentially links Rho and Rac signaling pathways
    • Horii, Y., Beeler, J. F., Sakaguchi, K., Tachibana, M. and Miki, T., A novel oncogene, Ost, encodes a guanine nucleotide exchange factor that potentially links Rho and Rac signaling pathways. EMBO J. 1994. 13: 4776-4786.
    • (1994) EMBO J. , vol.13 , pp. 4776-4786
    • Horii, Y.1    Beeler, J.F.2    Sakaguchi, K.3    Tachibana, M.4    Miki, T.5
  • 29
    • 0033584464 scopus 로고    scopus 로고
    • Distinct expression patterns and transforming properties of multiple isoforms of Ost, an exchange factor for RhoA and Cdc42
    • Lorenzi, M. V., Castagnino, P., Chen, Q., Hori, Y. and Miki, T., Distinct expression patterns and transforming properties of multiple isoforms of Ost, an exchange factor for RhoA and Cdc42. Oncogene 1999. 18: 4742-4755.
    • (1999) Oncogene , vol.18 , pp. 4742-4755
    • Lorenzi, M.V.1    Castagnino, P.2    Chen, Q.3    Hori, Y.4    Miki, T.5
  • 31
    • 0038418395 scopus 로고    scopus 로고
    • Critical role of the pleckstrin homology domain in dbs signaling and growth regulation
    • Fuentes, E. J., Karnoub, A. E., Booden, M. A., Der, C. J. and Campbell, S. L., Critical role of the pleckstrin homology domain in dbs signaling and growth regulation. J. Biol. Chem. 2003. 278: 21188-21196.
    • (2003) J. Biol. Chem. , vol.278 , pp. 21188-21196
    • Fuentes, E.J.1    Karnoub, A.E.2    Booden, M.A.3    Der, C.J.4    Campbell, S.L.5
  • 33
    • 0028115823 scopus 로고
    • Defective development of thymocytes overexpressing the costimulatory molecule, heat-stable antigen
    • Hough, M. R., Takei, F., Humphries, R. K. and Kay, R., Defective development of thymocytes overexpressing the costimulatory molecule, heat-stable antigen. J. Exp. Med. 1994. 179: 177-184.
    • (1994) J. Exp. Med. , vol.179 , pp. 177-184
    • Hough, M.R.1    Takei, F.2    Humphries, R.K.3    Kay, R.4
  • 34
    • 0032894087 scopus 로고    scopus 로고
    • Comparison of multiple assays for kinetic detection of apoptosis in thymocytes exposed to dexamethasone or diethylstilbesterol
    • Donner, K. J., Becker, K. M., Hissong, B. D. and Ahmed, S. A., Comparison of multiple assays for kinetic detection of apoptosis in thymocytes exposed to dexamethasone or diethylstilbesterol. Cytometry 1999. 35: 80-90.
    • (1999) Cytometry , vol.35 , pp. 80-90
    • Donner, K.J.1    Becker, K.M.2    Hissong, B.D.3    Ahmed, S.A.4
  • 36
    • 0028203979 scopus 로고
    • CD3 components at the surface of pro-T cells can mediate pre-T cell development in vivo
    • Jacobs, H., Vandeputte, D., Tolkamp, L., de Vries, E., Borst, J. and Berns, A., CD3 components at the surface of pro-T cells can mediate pre-T cell development in vivo. Eur. J. Immunol. 1994. 24: 934-939.
    • (1994) Eur. J. Immunol. , vol.24 , pp. 934-939
    • Jacobs, H.1    Vandeputte, D.2    Tolkamp, L.3    de Vries, E.4    Borst, J.5    Berns, A.6
  • 38
    • 0025897415 scopus 로고
    • In vivo administration of monoclonal anti-bodies to the CD3 T cell receptor complex induces cell death (apoptosis) in immature thymocytes
    • Shi, Y. F., Bissonnette, R. P., Parfrey, N., Szalay, M., Kubo, R. T. and Green, D. R., In vivo administration of monoclonal anti-bodies to the CD3 T cell receptor complex induces cell death (apoptosis) in immature thymocytes. J. Immunol. 1991. 146: 3340-3346.
    • (1991) J. Immunol. , vol.146 , pp. 3340-3346
    • Shi, Y.F.1    Bissonnette, R.P.2    Parfrey, N.3    Szalay, M.4    Kubo, R.T.5    Green, D.R.6
  • 40
    • 0036724188 scopus 로고    scopus 로고
    • Activation of rac and cdc42 video imaged by fluorescent resonance energy transfer-based single-molecule probes in the membrane of living cells
    • Itoh, R. E., Kurokawa, K., Ohba, Y., Yoshizaki, H., Mochizuki, N. and Matsuda, M., Activation of rac and cdc42 video imaged by fluorescent resonance energy transfer-based single-molecule probes in the membrane of living cells. Mol. Cell. Biol. 2002. 22: 6582-6591.
    • (2002) Mol. Cell. Biol. , vol.22 , pp. 6582-6591
    • Itoh, R.E.1    Kurokawa, K.2    Ohba, Y.3    Yoshizaki, H.4    Mochizuki, N.5    Matsuda, M.6
  • 41
    • 0027958423 scopus 로고
    • Cellular transformation and guanine nucleotide exchange activity are catalyzed by a common domain on the dbl oncogene product
    • Hart, M. J, Eva, A., Zangrilli, D., Aaronson, S. A., Evans, T., Cerione, R. A. and Zheng, Y., Cellular transformation and guanine nucleotide exchange activity are catalyzed by a common domain on the dbl oncogene product. J. Biol. Chem. 1994. 269: 62-65.
    • (1994) J. Biol. Chem. , vol.269 , pp. 62-65
    • Hart, M.J.1    Eva, A.2    Zangrilli, D.3    Aaronson, S.A.4    Evans, T.5    Cerione, R.A.6    Zheng, Y.7
  • 42
    • 0029166210 scopus 로고
    • Guanine nucleotide exchange catalyzed by dbl oncogene product
    • Zheng, Y., Hart, M. J. and Cerione, R. A., Guanine nucleotide exchange catalyzed by dbl oncogene product. Methods Enzymol. 1995. 256: 77-84.
    • (1995) Methods Enzymol. , vol.256 , pp. 77-84
    • Zheng, Y.1    Hart, M.J.2    Cerione, R.A.3
  • 43
    • 0037134436 scopus 로고    scopus 로고
    • Activation of clg, a novel dbl family guanine nucleotide exchange factor gene, by proviral insertion at evi24, a common integration site in B cell and myeloid leukemias
    • Himmel, K. L., Bi, F., Shen, H., Jenkins, N. A., Copeland, N. G., Zheng, Y. and Largaespada, D. A., Activation of clg, a novel dbl family guanine nucleotide exchange factor gene, by proviral insertion at evi24, a common integration site in B cell and myeloid leukemias. J. Biol. Chem. 2002. 277: 13463-13472.
    • (2002) J. Biol. Chem. , vol.277 , pp. 13463-13472
    • Himmel, K.L.1    Bi, F.2    Shen, H.3    Jenkins, N.A.4    Copeland, N.G.5    Zheng, Y.6    Largaespada, D.A.7


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