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Volumn 93, Issue 1, 2005, Pages 63-71

Selective gene silencing of rat ATP-binding cassette G2 transporter in an in vitro blood-brain barrier model by short interfering RNA

Author keywords

17 estradiol; ABC transporter; ATP binding cassette transporter G2; Blood brain barrier; In vitro blood brain barrier model; Short interfering RNA

Indexed keywords

ABC TRANSPORTER; ABC TRANSPORTER C1; ABC TRANSPORTER G1; BREAST CANCER RESISTANCE PROTEIN; ESTRADIOL; MULTIDRUG RESISTANCE PROTEIN 1; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

EID: 16244415183     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2004.02994.x     Document Type: Article
Times cited : (14)

References (29)
  • 1
    • 0001744641 scopus 로고    scopus 로고
    • Multidrug resistance and pharmacological protection mediated by the breast cancer resistance protein (BCRP/ABCG2)
    • Allen J. D. and Schinkel A. H. (2002) Multidrug resistance and pharmacological protection mediated by the breast cancer resistance protein (BCRP/ABCG2). Mol. Cancer Ther. 1, 427-434.
    • (2002) Mol. Cancer Ther. , vol.1 , pp. 427-434
    • Allen, J.D.1    Schinkel, A.H.2
  • 2
  • 3
    • 0033794507 scopus 로고    scopus 로고
    • Blood-brain barrier is involved in the efflux transport of a neuroactive steroid, dehydroepiandrosterone sulfate, via organic anion transporting polypeptide 2
    • Asaba H., Hosoya K., Takanaga H., Ohtsuki S., Tamura E., Takizawa T. and Terasaki T. (2000) Blood-brain barrier is involved in the efflux transport of a neuroactive steroid, dehydroepiandrosterone sulfate, via organic anion transporting polypeptide 2. J. Neurochem. 75, 1907-1916.
    • (2000) J. Neurochem. , vol.75 , pp. 1907-1916
    • Asaba, H.1    Hosoya, K.2    Takanaga, H.3    Ohtsuki, S.4    Tamura, E.5    Takizawa, T.6    Terasaki, T.7
  • 4
    • 0032695270 scopus 로고    scopus 로고
    • Reversal of resistance by GF120918 in cell lines expressing the ABC half-transporter, MXR
    • de Bruin M., Miyake K., Litman T., Robey R. and Bates S. E. (1999) Reversal of resistance by GF120918 in cell lines expressing the ABC half-transporter, MXR. Cancer Leu. 146, 117-126.
    • (1999) Cancer Leu. , vol.146 , pp. 117-126
    • De Bruin, M.1    Miyake, K.2    Litman, T.3    Robey, R.4    Bates, S.E.5
  • 5
    • 0035101145 scopus 로고    scopus 로고
    • Cellular and molecular pharmacology of antiestrogen action and resistance
    • Clarke R., Leonessa F., Welch J. N. and Skaar T. C. (2001) Cellular and molecular pharmacology of antiestrogen action and resistance. Pharmacol Rev. 53, 25-71.
    • (2001) Pharmacol Rev. , vol.53 , pp. 25-71
    • Clarke, R.1    Leonessa, F.2    Welch, J.N.3    Skaar, T.C.4
  • 6
    • 0037113346 scopus 로고    scopus 로고
    • Localisation of breast cancer resistance protein in microvessel endothelium of human brain
    • Cooray H. C., Blackmore C. G., Maskell L. and Barrand M. A. (2002) Localisation of breast cancer resistance protein in microvessel endothelium of human brain. Neuroreport 13, 2059-2063.
    • (2002) Neuroreport , vol.13 , pp. 2059-2063
    • Cooray, H.C.1    Blackmore, C.G.2    Maskell, L.3    Barrand, M.A.4
  • 7
    • 1242293680 scopus 로고    scopus 로고
    • Identification of a novel estrogen response element in the breast cancer resistance protein (ABCG2) gene
    • Ee P. L., Kamalakaran S., Tonetti D., He X., Ross D. D. and Beck W. T. (2004) Identification of a novel estrogen response element in the breast cancer resistance protein (ABCG2) gene. Cancer Res. 64, 1247-1251.
    • (2004) Cancer Res. , vol.64 , pp. 1247-1251
    • Ee, P.L.1    Kamalakaran, S.2    Tonetti, D.3    He, X.4    Ross, D.D.5    Beck, W.T.6
  • 8
    • 0036351317 scopus 로고    scopus 로고
    • Analysis of gene function in somatic mammalian cells using small interfering RNAs
    • Elbashir S. M., Harborth J., Weber K. and Tuschl T. (2002) Analysis of gene function in somatic mammalian cells using small interfering RNAs. Methods 26, 199-213.
    • (2002) Methods , vol.26 , pp. 199-213
    • Elbashir, S.M.1    Harborth, J.2    Weber, K.3    Tuschl, T.4
  • 9
    • 0032859340 scopus 로고    scopus 로고
    • Localization of the organic anion transporting polypeptide 2 (Oatp2) in capillary endothelium and choroid plexus epithelium of rat brain
    • Gao B., Stieger B., Noe B., Fritschy J. M. and Meier P. J. (1999) Localization of the organic anion transporting polypeptide 2 (Oatp2) in capillary endothelium and choroid plexus epithelium of rat brain. J. Histochem. Cytochem. 47, 1255-1264.
    • (1999) J. Histochem. Cytochem. , vol.47 , pp. 1255-1264
    • Gao, B.1    Stieger, B.2    Noe, B.3    Fritschy, J.M.4    Meier, P.J.5
  • 10
    • 0037062951 scopus 로고    scopus 로고
    • RNA interference
    • Hannon G. J. (2002) RNA interference. Nature 418, 244-251.
    • (2002) Nature , vol.418 , pp. 244-251
    • Hannon, G.J.1
  • 11
    • 3342996554 scopus 로고    scopus 로고
    • Functional expression of rat ABCG2 on the luminal side of brain capillaries and its enhancement by astrocyte-derived soluble factor(s)
    • Hori S., Ohtsuki S., Tachikawa M., Kimura N., Kondo T., Watanabe M., Nakashima E. and Terasaki T. (2004) Functional expression of rat ABCG2 on the luminal side of brain capillaries and its enhancement by astrocyte-derived soluble factor(s). J. Neurochem. 90, 526-536.
    • (2004) J. Neurochem. , vol.90 , pp. 526-536
    • Hori, S.1    Ohtsuki, S.2    Tachikawa, M.3    Kimura, N.4    Kondo, T.5    Watanabe, M.6    Nakashima, E.7    Terasaki, T.8
  • 12
    • 0034452792 scopus 로고    scopus 로고
    • mRNA expression and transport characterization of conditionally immortalized rat brain capillary endothelial cell lines; a new in vitro BBB model for drug targeting
    • Hosoya K., Takashima T., Tetsuka K. et al. (2000a) mRNA expression and transport characterization of conditionally immortalized rat brain capillary endothelial cell lines; a new in vitro BBB model for drug targeting. J. Drug Target. 8, 357-370.
    • (2000) J. Drug Target , vol.8 , pp. 357-370
    • Hosoya, K.1    Takashima, T.2    Tetsuka, K.3
  • 13
    • 1042283687 scopus 로고    scopus 로고
    • Conditionally immortalized brain capillary endothelial cell lines established from a transgenic mouse harboring temperature-sensitive simian virus 40 large T-antigen gene
    • article 27. doi: 10.128/ps020327
    • Hosoya K., Tetsuka K., Nagase K. et al. (2000b) Conditionally immortalized brain capillary endothelial cell lines established from a transgenic mouse harboring temperature-sensitive simian virus 40 large T-antigen gene. AAPS Pharmsci. 2, article 27. doi: 10.128/ ps020327 Available: http://www.aapspharmsci.org
    • (2000) AAPS Pharmsci. , vol.2
    • Hosoya, K.1    Tetsuka, K.2    Nagase, K.3
  • 14
    • 0037032467 scopus 로고    scopus 로고
    • Recent advances in the brain-to-blood efflux transport across the blood-brain barrier
    • Hosoya K., Ohtsuki S. and Terasaki T. (2002) Recent advances in the brain-to-blood efflux transport across the blood-brain barrier. Int. J. Pharm. 248, 15-29.
    • (2002) Int. J. Pharm. , vol.248 , pp. 15-29
    • Hosoya, K.1    Ohtsuki, S.2    Terasaki, T.3
  • 15
    • 0027524642 scopus 로고
    • In vitro and in vivo reversal of multidrug resistance by GF120918, an acridonecarboxamide derivative
    • Hyafil F., Vergely C., Du Vignaud P. and Grand-Perret T. (1993) in vitro and in vivo reversal of multidrug resistance by GF120918, an acridonecarboxamide derivative. Cancer Res. 53, 4595-4602.
    • (1993) Cancer Res. , vol.53 , pp. 4595-4602
    • Hyafil, F.1    Vergely, C.2    Du Vignaud, P.3    Grand-Perret, T.4
  • 16
    • 0037383621 scopus 로고    scopus 로고
    • Rat organic anion transporter 3 (rOAT3) is responsible for brain-to-blood efflux of homovanillic acid at the abluminal membrane of brain capillary endothelial cells
    • Mori S., Takanaga H., Ohtsuki S., Deguchi T., Kang Y. S., Hosoya K. and Terasaki T. (2003) Rat organic anion transporter 3 (rOAT3) is responsible for brain-to-blood efflux of homovanillic acid at the abluminal membrane of brain capillary endothelial cells. J. Cereb. Blood Flow Metab. 23, 432-440.
    • (2003) J. Cereb. Blood Flow Metab. , vol.23 , pp. 432-440
    • Mori, S.1    Takanaga, H.2    Ohtsuki, S.3    Deguchi, T.4    Kang, Y.S.5    Hosoya, K.6    Terasaki, T.7
  • 17
    • 2942655711 scopus 로고    scopus 로고
    • Mechanism and regulation of folate uptake by the human pancreatic epithelial MIA PaCa-2 cells
    • Nabokina S. M., Ma T. Y. and Said H. M. (2004) Mechanism and regulation of folate uptake by the human pancreatic epithelial MIA PaCa-2 cells. Am. J. Physiol. Cell Physiol. 287, C142-C148.
    • (2004) Am. J. Physiol. Cell Physiol. , vol.287
    • Nabokina, S.M.1    Ma, T.Y.2    Said, H.M.3
  • 18
    • 0033966957 scopus 로고    scopus 로고
    • Fumitremorgin C reverses multidrug resistance in cells transfected with the breast cancer resistance protein
    • Rabindran S. K., Ross D. D., Doyle L. A., Yang W. and Greenberger L. M. (2000) Fumitremorgin C reverses multidrug resistance in cells transfected with the breast cancer resistance protein. Cancer Res. 60, 47-50.
    • (2000) Cancer Res. , vol.60 , pp. 47-50
    • Rabindran, S.K.1    Ross, D.D.2    Doyle, L.A.3    Yang, W.4    Greenberger, L.M.5
  • 21
    • 0037225649 scopus 로고    scopus 로고
    • Multiple forms of estrogen receptor-alpha in cerebral blood vessels: Regulation by estrogen
    • Stirone C., Duckles S. P. and Krause D. N. (2003) Multiple forms of estrogen receptor-alpha in cerebral blood vessels: regulation by estrogen. Am. J. Physiol. Endocrinol Metab. 284, E184-E192.
    • (2003) Am. J. Physiol. Endocrinol Metab. , vol.284
    • Stirone, C.1    Duckles, S.P.2    Krause, D.N.3
  • 22
    • 0038265441 scopus 로고    scopus 로고
    • ABCG2 transports sulfated conjugates of steroids and xenobiotics
    • Suzuki M., Suzuki H., Sugimoto Y. and Sugiyama Y. (2003) ABCG2 transports sulfated conjugates of steroids and xenobiotics. J. Biol. Chem. 278, 22 644-22 649.
    • (2003) J. Biol. Chem. , vol.278
    • Suzuki, M.1    Suzuki, H.2    Sugimoto, Y.3    Sugiyama, Y.4
  • 23
    • 0033526186 scopus 로고    scopus 로고
    • The blood-brain barrier efflux transporters as a detoxifying system for the brain
    • Terasaki T. and Hosoya K. (1999) The blood-brain barrier efflux transporters as a detoxifying system for the brain. Adv. Drug Deliv. Rev. 36, 195-209.
    • (1999) Adv. Drug Deliv. Rev. , vol.36 , pp. 195-209
    • Terasaki, T.1    Hosoya, K.2
  • 26
    • 0037380839 scopus 로고    scopus 로고
    • Small interfering RNA-induced suppression of MDR1 (P-glycoprotein) restores sensitivity to multidrug-resistant cancer cells
    • Wu H., Hait W. N. and Yang J. M. (2003) Small interfering RNA-induced suppression of MDR1 (P-glycoprotein) restores sensitivity to multidrug-resistant cancer cells. Cancer Res. 63, 1515-1519.
    • (2003) Cancer Res. , vol.63 , pp. 1515-1519
    • Wu, H.1    Hait, W.N.2    Yang, J.M.3
  • 27
    • 1342306353 scopus 로고    scopus 로고
    • Effects on RNAi of the tight structure, sequence and position of the targeted region
    • Yoshinari K., Miyagishi M. and Taira K. (2004) Effects on RNAi of the tight structure, sequence and position of the targeted region. Nucl Acids Res. 32, 691-699.
    • (2004) Nucl Acids Res , vol.32 , pp. 691-699
    • Yoshinari, K.1    Miyagishi, M.2    Taira, K.3
  • 28
    • 0037693882 scopus 로고    scopus 로고
    • Steroid and bile acid conjugates are substrates of human multidrug-resistance protein (MRP)4 (ATP-binding cassette C4)
    • Zelcer N., Reid G., Wielinga P., Kuil A., van der Heijden I., Schuetz J. D. and Borst P. (2003) Steroid and bile acid conjugates are substrates of human multidrug-resistance protein (MRP)4 (ATP-binding cassette C4). Biochem. J. 371, 361-367.
    • (2003) Biochem. J. , vol.371 , pp. 361-367
    • Zelcer, N.1    Reid, G.2    Wielinga, P.3    Kuil, A.4    Van Der Heijden, I.5    Schuetz, J.D.6    Borst, P.7
  • 29
    • 1942523210 scopus 로고    scopus 로고
    • In vivo knockdown of gene expression in brain cancer with intravenous RNAi in adult rats
    • Zhang Y., Boado R. J. and Pardridge W. M. (2003) In vivo knockdown of gene expression in brain cancer with intravenous RNAi in adult rats. J. Gene Med. 5, 1039-1045.
    • (2003) J. Gene Med. , vol.5 , pp. 1039-1045
    • Zhang, Y.1    Boado, R.J.2    Pardridge, W.M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.