-
1
-
-
0001744641
-
Multidrug resistance and pharmacological protection mediated by the breast cancer resistance protein (BCRP/ABCG2)
-
Allen J. D. and Schinkel A. H. (2002) Multidrug resistance and pharmacological protection mediated by the breast cancer resistance protein (BCRP/ABCG2). Mol. Cancer Ther. 1, 427-434.
-
(2002)
Mol. Cancer Ther.
, vol.1
, pp. 427-434
-
-
Allen, J.D.1
Schinkel, A.H.2
-
2
-
-
0000890967
-
Potent and specific inhibition of the breast cancer resistance protein multidrug transporter in vitro and in mouse intestine by a novel analogue of fumitremorgin C
-
Allen J. D., van Loevezijn A., Lakhai J. M., van der Valk M., van Tellingen O., Reid G., Schellens J. H., Koomen G. J. and Schinkel A. H. (2002) Potent and specific inhibition of the breast cancer resistance protein multidrug transporter in vitro and in mouse intestine by a novel analogue of fumitremorgin C. Mol. Cancer Ther. 1, 417-425.
-
(2002)
Mol. Cancer Ther.
, vol.1
, pp. 417-425
-
-
Allen, J.D.1
Van Loevezijn, A.2
Lakhai, J.M.3
Van Der Valk, M.4
Van Tellingen, O.5
Reid, G.6
Schellens, J.H.7
Koomen, G.J.8
Schinkel, A.H.9
-
3
-
-
0033794507
-
Blood-brain barrier is involved in the efflux transport of a neuroactive steroid, dehydroepiandrosterone sulfate, via organic anion transporting polypeptide 2
-
Asaba H., Hosoya K., Takanaga H., Ohtsuki S., Tamura E., Takizawa T. and Terasaki T. (2000) Blood-brain barrier is involved in the efflux transport of a neuroactive steroid, dehydroepiandrosterone sulfate, via organic anion transporting polypeptide 2. J. Neurochem. 75, 1907-1916.
-
(2000)
J. Neurochem.
, vol.75
, pp. 1907-1916
-
-
Asaba, H.1
Hosoya, K.2
Takanaga, H.3
Ohtsuki, S.4
Tamura, E.5
Takizawa, T.6
Terasaki, T.7
-
4
-
-
0032695270
-
Reversal of resistance by GF120918 in cell lines expressing the ABC half-transporter, MXR
-
de Bruin M., Miyake K., Litman T., Robey R. and Bates S. E. (1999) Reversal of resistance by GF120918 in cell lines expressing the ABC half-transporter, MXR. Cancer Leu. 146, 117-126.
-
(1999)
Cancer Leu.
, vol.146
, pp. 117-126
-
-
De Bruin, M.1
Miyake, K.2
Litman, T.3
Robey, R.4
Bates, S.E.5
-
5
-
-
0035101145
-
Cellular and molecular pharmacology of antiestrogen action and resistance
-
Clarke R., Leonessa F., Welch J. N. and Skaar T. C. (2001) Cellular and molecular pharmacology of antiestrogen action and resistance. Pharmacol Rev. 53, 25-71.
-
(2001)
Pharmacol Rev.
, vol.53
, pp. 25-71
-
-
Clarke, R.1
Leonessa, F.2
Welch, J.N.3
Skaar, T.C.4
-
6
-
-
0037113346
-
Localisation of breast cancer resistance protein in microvessel endothelium of human brain
-
Cooray H. C., Blackmore C. G., Maskell L. and Barrand M. A. (2002) Localisation of breast cancer resistance protein in microvessel endothelium of human brain. Neuroreport 13, 2059-2063.
-
(2002)
Neuroreport
, vol.13
, pp. 2059-2063
-
-
Cooray, H.C.1
Blackmore, C.G.2
Maskell, L.3
Barrand, M.A.4
-
7
-
-
1242293680
-
Identification of a novel estrogen response element in the breast cancer resistance protein (ABCG2) gene
-
Ee P. L., Kamalakaran S., Tonetti D., He X., Ross D. D. and Beck W. T. (2004) Identification of a novel estrogen response element in the breast cancer resistance protein (ABCG2) gene. Cancer Res. 64, 1247-1251.
-
(2004)
Cancer Res.
, vol.64
, pp. 1247-1251
-
-
Ee, P.L.1
Kamalakaran, S.2
Tonetti, D.3
He, X.4
Ross, D.D.5
Beck, W.T.6
-
8
-
-
0036351317
-
Analysis of gene function in somatic mammalian cells using small interfering RNAs
-
Elbashir S. M., Harborth J., Weber K. and Tuschl T. (2002) Analysis of gene function in somatic mammalian cells using small interfering RNAs. Methods 26, 199-213.
-
(2002)
Methods
, vol.26
, pp. 199-213
-
-
Elbashir, S.M.1
Harborth, J.2
Weber, K.3
Tuschl, T.4
-
9
-
-
0032859340
-
Localization of the organic anion transporting polypeptide 2 (Oatp2) in capillary endothelium and choroid plexus epithelium of rat brain
-
Gao B., Stieger B., Noe B., Fritschy J. M. and Meier P. J. (1999) Localization of the organic anion transporting polypeptide 2 (Oatp2) in capillary endothelium and choroid plexus epithelium of rat brain. J. Histochem. Cytochem. 47, 1255-1264.
-
(1999)
J. Histochem. Cytochem.
, vol.47
, pp. 1255-1264
-
-
Gao, B.1
Stieger, B.2
Noe, B.3
Fritschy, J.M.4
Meier, P.J.5
-
10
-
-
0037062951
-
RNA interference
-
Hannon G. J. (2002) RNA interference. Nature 418, 244-251.
-
(2002)
Nature
, vol.418
, pp. 244-251
-
-
Hannon, G.J.1
-
11
-
-
3342996554
-
Functional expression of rat ABCG2 on the luminal side of brain capillaries and its enhancement by astrocyte-derived soluble factor(s)
-
Hori S., Ohtsuki S., Tachikawa M., Kimura N., Kondo T., Watanabe M., Nakashima E. and Terasaki T. (2004) Functional expression of rat ABCG2 on the luminal side of brain capillaries and its enhancement by astrocyte-derived soluble factor(s). J. Neurochem. 90, 526-536.
-
(2004)
J. Neurochem.
, vol.90
, pp. 526-536
-
-
Hori, S.1
Ohtsuki, S.2
Tachikawa, M.3
Kimura, N.4
Kondo, T.5
Watanabe, M.6
Nakashima, E.7
Terasaki, T.8
-
12
-
-
0034452792
-
mRNA expression and transport characterization of conditionally immortalized rat brain capillary endothelial cell lines; a new in vitro BBB model for drug targeting
-
Hosoya K., Takashima T., Tetsuka K. et al. (2000a) mRNA expression and transport characterization of conditionally immortalized rat brain capillary endothelial cell lines; a new in vitro BBB model for drug targeting. J. Drug Target. 8, 357-370.
-
(2000)
J. Drug Target
, vol.8
, pp. 357-370
-
-
Hosoya, K.1
Takashima, T.2
Tetsuka, K.3
-
13
-
-
1042283687
-
Conditionally immortalized brain capillary endothelial cell lines established from a transgenic mouse harboring temperature-sensitive simian virus 40 large T-antigen gene
-
article 27. doi: 10.128/ps020327
-
Hosoya K., Tetsuka K., Nagase K. et al. (2000b) Conditionally immortalized brain capillary endothelial cell lines established from a transgenic mouse harboring temperature-sensitive simian virus 40 large T-antigen gene. AAPS Pharmsci. 2, article 27. doi: 10.128/ ps020327 Available: http://www.aapspharmsci.org
-
(2000)
AAPS Pharmsci.
, vol.2
-
-
Hosoya, K.1
Tetsuka, K.2
Nagase, K.3
-
14
-
-
0037032467
-
Recent advances in the brain-to-blood efflux transport across the blood-brain barrier
-
Hosoya K., Ohtsuki S. and Terasaki T. (2002) Recent advances in the brain-to-blood efflux transport across the blood-brain barrier. Int. J. Pharm. 248, 15-29.
-
(2002)
Int. J. Pharm.
, vol.248
, pp. 15-29
-
-
Hosoya, K.1
Ohtsuki, S.2
Terasaki, T.3
-
15
-
-
0027524642
-
In vitro and in vivo reversal of multidrug resistance by GF120918, an acridonecarboxamide derivative
-
Hyafil F., Vergely C., Du Vignaud P. and Grand-Perret T. (1993) in vitro and in vivo reversal of multidrug resistance by GF120918, an acridonecarboxamide derivative. Cancer Res. 53, 4595-4602.
-
(1993)
Cancer Res.
, vol.53
, pp. 4595-4602
-
-
Hyafil, F.1
Vergely, C.2
Du Vignaud, P.3
Grand-Perret, T.4
-
16
-
-
0037383621
-
Rat organic anion transporter 3 (rOAT3) is responsible for brain-to-blood efflux of homovanillic acid at the abluminal membrane of brain capillary endothelial cells
-
Mori S., Takanaga H., Ohtsuki S., Deguchi T., Kang Y. S., Hosoya K. and Terasaki T. (2003) Rat organic anion transporter 3 (rOAT3) is responsible for brain-to-blood efflux of homovanillic acid at the abluminal membrane of brain capillary endothelial cells. J. Cereb. Blood Flow Metab. 23, 432-440.
-
(2003)
J. Cereb. Blood Flow Metab.
, vol.23
, pp. 432-440
-
-
Mori, S.1
Takanaga, H.2
Ohtsuki, S.3
Deguchi, T.4
Kang, Y.S.5
Hosoya, K.6
Terasaki, T.7
-
17
-
-
2942655711
-
Mechanism and regulation of folate uptake by the human pancreatic epithelial MIA PaCa-2 cells
-
Nabokina S. M., Ma T. Y. and Said H. M. (2004) Mechanism and regulation of folate uptake by the human pancreatic epithelial MIA PaCa-2 cells. Am. J. Physiol. Cell Physiol. 287, C142-C148.
-
(2004)
Am. J. Physiol. Cell Physiol.
, vol.287
-
-
Nabokina, S.M.1
Ma, T.Y.2
Said, H.M.3
-
18
-
-
0033966957
-
Fumitremorgin C reverses multidrug resistance in cells transfected with the breast cancer resistance protein
-
Rabindran S. K., Ross D. D., Doyle L. A., Yang W. and Greenberger L. M. (2000) Fumitremorgin C reverses multidrug resistance in cells transfected with the breast cancer resistance protein. Cancer Res. 60, 47-50.
-
(2000)
Cancer Res.
, vol.60
, pp. 47-50
-
-
Rabindran, S.K.1
Ross, D.D.2
Doyle, L.A.3
Yang, W.4
Greenberger, L.M.5
-
19
-
-
1542336952
-
Rational siRNA design for RNA interference
-
Reynolds A., Leake D., Boese Q., Scaringe S., Marshall W. S. and Khvorova A. (2004) Rational siRNA design for RNA interference. Nat. Biotechnol. 22, 326-330.
-
(2004)
Nat. Biotechnol.
, vol.22
, pp. 326-330
-
-
Reynolds, A.1
Leake, D.2
Boese, Q.3
Scaringe, S.4
Marshall, W.S.5
Khvorova, A.6
-
21
-
-
0037225649
-
Multiple forms of estrogen receptor-alpha in cerebral blood vessels: Regulation by estrogen
-
Stirone C., Duckles S. P. and Krause D. N. (2003) Multiple forms of estrogen receptor-alpha in cerebral blood vessels: regulation by estrogen. Am. J. Physiol. Endocrinol Metab. 284, E184-E192.
-
(2003)
Am. J. Physiol. Endocrinol Metab.
, vol.284
-
-
Stirone, C.1
Duckles, S.P.2
Krause, D.N.3
-
22
-
-
0038265441
-
ABCG2 transports sulfated conjugates of steroids and xenobiotics
-
Suzuki M., Suzuki H., Sugimoto Y. and Sugiyama Y. (2003) ABCG2 transports sulfated conjugates of steroids and xenobiotics. J. Biol. Chem. 278, 22 644-22 649.
-
(2003)
J. Biol. Chem.
, vol.278
-
-
Suzuki, M.1
Suzuki, H.2
Sugimoto, Y.3
Sugiyama, Y.4
-
23
-
-
0033526186
-
The blood-brain barrier efflux transporters as a detoxifying system for the brain
-
Terasaki T. and Hosoya K. (1999) The blood-brain barrier efflux transporters as a detoxifying system for the brain. Adv. Drug Deliv. Rev. 36, 195-209.
-
(1999)
Adv. Drug Deliv. Rev.
, vol.36
, pp. 195-209
-
-
Terasaki, T.1
Hosoya, K.2
-
24
-
-
0141923651
-
New approaches to in vitro models of blood-brain barrier drug transport
-
Terasaki T., Ohtsuki S., Hori S., Takanaga H., Nakashima E. and Hosoya K. (2003) New approaches to in vitro models of blood-brain barrier drug transport. Drug Discov. Today 8, 944-954.
-
(2003)
Drug Discov. Today
, vol.8
, pp. 944-954
-
-
Terasaki, T.1
Ohtsuki, S.2
Hori, S.3
Takanaga, H.4
Nakashima, E.5
Hosoya, K.6
-
25
-
-
0036936117
-
Expression of P-glycoprotein in human cerebral cortex microvessels
-
Virgintino D., Robertson D., Errede M., Benagiano V., Girolamo F., Matorano E., Roncali L. and Bertossi M. (2002) Expression of P-glycoprotein in human cerebral cortex microvessels. J. Histochem. Cytochem. 50, 1671-1676.
-
(2002)
J. Histochem. Cytochem.
, vol.50
, pp. 1671-1676
-
-
Virgintino, D.1
Robertson, D.2
Errede, M.3
Benagiano, V.4
Girolamo, F.5
Matorano, E.6
Roncali, L.7
Bertossi, M.8
-
26
-
-
0037380839
-
Small interfering RNA-induced suppression of MDR1 (P-glycoprotein) restores sensitivity to multidrug-resistant cancer cells
-
Wu H., Hait W. N. and Yang J. M. (2003) Small interfering RNA-induced suppression of MDR1 (P-glycoprotein) restores sensitivity to multidrug-resistant cancer cells. Cancer Res. 63, 1515-1519.
-
(2003)
Cancer Res.
, vol.63
, pp. 1515-1519
-
-
Wu, H.1
Hait, W.N.2
Yang, J.M.3
-
27
-
-
1342306353
-
Effects on RNAi of the tight structure, sequence and position of the targeted region
-
Yoshinari K., Miyagishi M. and Taira K. (2004) Effects on RNAi of the tight structure, sequence and position of the targeted region. Nucl Acids Res. 32, 691-699.
-
(2004)
Nucl Acids Res
, vol.32
, pp. 691-699
-
-
Yoshinari, K.1
Miyagishi, M.2
Taira, K.3
-
28
-
-
0037693882
-
Steroid and bile acid conjugates are substrates of human multidrug-resistance protein (MRP)4 (ATP-binding cassette C4)
-
Zelcer N., Reid G., Wielinga P., Kuil A., van der Heijden I., Schuetz J. D. and Borst P. (2003) Steroid and bile acid conjugates are substrates of human multidrug-resistance protein (MRP)4 (ATP-binding cassette C4). Biochem. J. 371, 361-367.
-
(2003)
Biochem. J.
, vol.371
, pp. 361-367
-
-
Zelcer, N.1
Reid, G.2
Wielinga, P.3
Kuil, A.4
Van Der Heijden, I.5
Schuetz, J.D.6
Borst, P.7
-
29
-
-
1942523210
-
In vivo knockdown of gene expression in brain cancer with intravenous RNAi in adult rats
-
Zhang Y., Boado R. J. and Pardridge W. M. (2003) In vivo knockdown of gene expression in brain cancer with intravenous RNAi in adult rats. J. Gene Med. 5, 1039-1045.
-
(2003)
J. Gene Med.
, vol.5
, pp. 1039-1045
-
-
Zhang, Y.1
Boado, R.J.2
Pardridge, W.M.3
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