-
1
-
-
0032575688
-
The Bcl-2 protein family: Arbiters of cell survival
-
J.M. Adams, and S. Cory The Bcl-2 protein family: arbiters of cell survival Science 281 1998 1322 1326
-
(1998)
Science
, vol.281
, pp. 1322-1326
-
-
Adams, J.M.1
Cory, S.2
-
2
-
-
0035876483
-
BH3-only proteins that bind pro-survival Bcl-2 family members fail to induce apoptosis in the absence of Bax and Bak
-
W.-X. Zong, T. Lindsten, A.J. Ross, G.R. MacGregor, and C.B. Thompson BH3-only proteins that bind pro-survival Bcl-2 family members fail to induce apoptosis in the absence of Bax and Bak Genes Dev. 15 2001 1481 1486
-
(2001)
Genes Dev.
, vol.15
, pp. 1481-1486
-
-
Zong, W.-X.1
Lindsten, T.2
Ross, A.J.3
MacGregor, G.R.4
Thompson, C.B.5
-
3
-
-
0035957653
-
Proapoptotic BAX and BAK: A requisite gateway to mitochondrial dysfunction and death
-
M.C. Wei, W.-X. Zong, E.H. Cheng, T. Lindsten, V. Panoutsakopoulou, and A.J. Ross Proapoptotic BAX and BAK: a requisite gateway to mitochondrial dysfunction and death Science 292 2001 727 730
-
(2001)
Science
, vol.292
, pp. 727-730
-
-
Wei, M.C.1
Zong, W.-X.2
Cheng, E.H.3
Lindsten, T.4
Panoutsakopoulou, V.5
Ross, A.J.6
-
6
-
-
0037458540
-
Bcl-2 on the endoplasmic reticulum regulates Bax activity by binding to BH3-only proteins
-
M.J. Thomenius, N.S. Wang, E.Z. Reineks, Z. Wang, and C.W. Distelhorst Bcl-2 on the endoplasmic reticulum regulates Bax activity by binding to BH3-only proteins J. Biol. Chem. 278 2003 6243 6250
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 6243-6250
-
-
Thomenius, M.J.1
Wang, N.S.2
Reineks, E.Z.3
Wang, Z.4
Distelhorst, C.W.5
-
7
-
-
0345732497
-
L differentially protect human prostate cancer cells from induction of apoptosis by melanoma differentiation associated gene-7, mda-7/IL-24
-
L differentially protect human prostate cancer cells from induction of apoptosis by melanoma differentiation associated gene-7, mda-7/IL-24 Oncogene 22 2003 8758 8773
-
(2003)
Oncogene
, vol.22
, pp. 8758-8773
-
-
Lebedeva, I.V.1
Sarkar, D.2
Su, Z.Z.3
Kitada, S.4
Den, P.5
Stein, C.A.6
-
8
-
-
0030795866
-
L can differentially block chemotherapy-induced cell death
-
L can differentially block chemotherapy-induced cell death Blood 90 2000 1208 1216
-
(2000)
Blood
, vol.90
, pp. 1208-1216
-
-
Simonian, P.L.1
Didier, A.M.2
Nunez, G.3
-
10
-
-
4544343214
-
A Bcr/Abl-independent, Lyn-dependent form of imatinib mesylate (STI-571) resistance is associated with altered expression of Bcl-2
-
Y. Dai, M. Rahmani, S.J. Corey, P. Dent, and S. Grant A Bcr/Abl-independent, Lyn-dependent form of imatinib mesylate (STI-571) resistance is associated with altered expression of Bcl-2 J. Biol. Chem. 279 2004 34227 34239
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 34227-34239
-
-
Dai, Y.1
Rahmani, M.2
Corey, S.J.3
Dent, P.4
Grant, S.5
-
11
-
-
1442335327
-
Shooting at survivors: Bcl-2 family members as drug targets for cancer
-
P. Juin, O. Geneste, E. Raimbaud, and J.A. Hickman Shooting at survivors: Bcl-2 family members as drug targets for cancer Biochim. Biophys. Acta 1644 2004 251 260
-
(2004)
Biochim. Biophys. Acta
, vol.1644
, pp. 251-260
-
-
Juin, P.1
Geneste, O.2
Raimbaud, E.3
Hickman, J.A.4
-
12
-
-
0034654522
-
Cell permeable Bcl-2 binding peptides: A chemical approach to apoptosis induction in tumor cells
-
J.L. Wang, Z.J. Zhang, S. Choksi, S. Shan, Z. Lu, and C.M. Croce Cell permeable Bcl-2 binding peptides: a chemical approach to apoptosis induction in tumor cells Cancer Res. 60 2000 1498 1502
-
(2000)
Cancer Res.
, vol.60
, pp. 1498-1502
-
-
Wang, J.L.1
Zhang, Z.J.2
Choksi, S.3
Shan, S.4
Lu, Z.5
Croce, C.M.6
-
13
-
-
0034691130
-
Structure-based discovery of an organic compound that binds Bcl-2 protein and induces apoptosis of tumor cells
-
J.L. Wang, D. Liu, Z.J. Zhang, S. Shan, X. Han, and S.M. Srinivasula Structure-based discovery of an organic compound that binds Bcl-2 protein and induces apoptosis of tumor cells Proc. Natl Acad. Sci. USA 97 2000 7124 7129
-
(2000)
Proc. Natl Acad. Sci. USA
, vol.97
, pp. 7124-7129
-
-
Wang, J.L.1
Liu, D.2
Zhang, Z.J.3
Shan, S.4
Han, X.5
Srinivasula, S.M.6
-
14
-
-
2442508985
-
Critical upstream signals of cytochrome C release induced by a novel Bcl-2 inhibitor
-
J. An, Y. Chen, and Z. Huang Critical upstream signals of cytochrome C release induced by a novel Bcl-2 inhibitor J. Biol. Chem. 279 2004 19133 19140
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 19133-19140
-
-
An, J.1
Chen, Y.2
Huang, Z.3
-
15
-
-
2442685708
-
Bcl-2 inhibitors sensitize tumor necrosis factor-related apoptosis inducing ligand-induced apoptosis by uncoupling of mitochondrial respiration in human leukemic CEM cells
-
J.H. Hao, M. Yu, F.T. Liu, A.C. Newland, and L. Jia Bcl-2 inhibitors sensitize tumor necrosis factor-related apoptosis inducing ligand-induced apoptosis by uncoupling of mitochondrial respiration in human leukemic CEM cells Cancer Res. 64 2004 3607 3616
-
(2004)
Cancer Res.
, vol.64
, pp. 3607-3616
-
-
Hao, J.H.1
Yu, M.2
Liu, F.T.3
Newland, A.C.4
Jia, L.5
-
16
-
-
0036730823
-
Apoptotic response to photodynamic therapy versus the Bcl-2 antagonist HA14-1
-
D. Kessel, M. Castelli, and J.J. Reiners Jr. Apoptotic response to photodynamic therapy versus the Bcl-2 antagonist HA14-1 Photochem. Photobiol. 76 2002 314 319
-
(2002)
Photochem. Photobiol.
, vol.76
, pp. 314-319
-
-
Kessel, D.1
Castelli, M.2
Reiners Jr., J.J.3
-
17
-
-
0033789323
-
1 phase-dependent expression of Bcl-2 mRNA and protein correlates with chemoresistance of human cancer cells
-
1 phase-dependent expression of Bcl-2 mRNA and protein correlates with chemoresistance of human cancer cells Mol. Pharmacol. 58 2000 1001 1010
-
(2000)
Mol. Pharmacol.
, vol.58
, pp. 1001-1010
-
-
Gao, G.1
Dou, Q.P.2
-
19
-
-
0033609299
-
Loss of the Bcl-2 phosphorylation loop domain increases resistance of human leukemia cells (U937) to paclitaxel-mediated mitochondrial dysfunction and apoptosis
-
S. Wang, Z. Wang, L. Boise, P. Dent, and S. Grant Loss of the Bcl-2 phosphorylation loop domain increases resistance of human leukemia cells (U937) to paclitaxel-mediated mitochondrial dysfunction and apoptosis Biochem. Biophys. Res. Commun. 259 1999 67 72
-
(1999)
Biochem. Biophys. Res. Commun.
, vol.259
, pp. 67-72
-
-
Wang, S.1
Wang, Z.2
Boise, L.3
Dent, P.4
Grant, S.5
-
21
-
-
0142244338
-
The proteasome inhibitor bortezomib promotes mitochondrial injury and apoptosis induced by the small molecule Bcl-2 inhibitor HA14-1 in multiple myeloma cells
-
X.Y. Pei, Y. Dai, and S. Grant The proteasome inhibitor bortezomib promotes mitochondrial injury and apoptosis induced by the small molecule Bcl-2 inhibitor HA14-1 in multiple myeloma cells Leukemia 17 2003 2036 2045
-
(2003)
Leukemia
, vol.17
, pp. 2036-2045
-
-
Pei, X.Y.1
Dai, Y.2
Grant, S.3
-
22
-
-
0242475256
-
HA14-1 selectively induces apoptosis in Bcl-2 overexpressing leukemia/lymphoma cells, and enhances cytarabine-induced cell death
-
J.D. Lickiliter, N.J. Wood, L. Johnson, G. McHugh, J. Tan, and F. Wood HA14-1 selectively induces apoptosis in Bcl-2 overexpressing leukemia/lymphoma cells, and enhances cytarabine-induced cell death Leukemia 17 2003 2074 2080
-
(2003)
Leukemia
, vol.17
, pp. 2074-2080
-
-
Lickiliter, J.D.1
Wood, N.J.2
Johnson, L.3
McHugh, G.4
Tan, J.5
Wood, F.6
-
23
-
-
0037081329
-
Epothilone B analogue (BMS-247550)-mediated cytotoxicity through induction of Bax conformational change in human breast cancer cells
-
H. Yamaguchi, S.R. Paranawithana, M.W. Lee, Z. Huang, K.N. Bhalla, and H-G. Wang Epothilone B analogue (BMS-247550)-mediated cytotoxicity through induction of Bax conformational change in human breast cancer cells Cancer Res. 62 2002 466 471
-
(2002)
Cancer Res.
, vol.62
, pp. 466-471
-
-
Yamaguchi, H.1
Paranawithana, S.R.2
Lee, M.W.3
Huang, Z.4
Bhalla, K.N.5
Wang, H.-G.6
-
24
-
-
3042766027
-
The apoptotic effect of HA14-1, a Bcl-2-interacting small molecular compound, requires Bax translocation and is enhanced by PK11195
-
J. Chen, A. Freeman, J. Liu, Q. Dai, and R.M. Lee The apoptotic effect of HA14-1, a Bcl-2-interacting small molecular compound, requires Bax translocation and is enhanced by PK11195 Mol. Cancer Ther. 1 2002 961 967
-
(2002)
Mol. Cancer Ther.
, vol.1
, pp. 961-967
-
-
Chen, J.1
Freeman, A.2
Liu, J.3
Dai, Q.4
Lee, R.M.5
-
25
-
-
0036566242
-
Synergistic induction of apoptosis by simultaneous disruption of the Bcl-2 and MEK/MAPK pathways in acute myelogenous leukemia
-
M. Milella, Z. Estrov, S.M. Kornblau, B.Z. Carter, M. Konopleva, and A. Tari Synergistic induction of apoptosis by simultaneous disruption of the Bcl-2 and MEK/MAPK pathways in acute myelogenous leukemia Blood 99 2002 3461 3464
-
(2002)
Blood
, vol.99
, pp. 3461-3464
-
-
Milella, M.1
Estrov, Z.2
Kornblau, S.M.3
Carter, B.Z.4
Konopleva, M.5
Tari, A.6
-
26
-
-
0034823632
-
Therapeutic targeting of the MEK/MAPK signal transduction module in acute myeloid leukemia
-
M. Milella, S.M. Kornblau, Z. Estrov, B.Z. Carter, H. Lapillonne, and D. Harris Therapeutic targeting of the MEK/MAPK signal transduction module in acute myeloid leukemia J. Clin. Invest. 108 2001 851 859
-
(2001)
J. Clin. Invest.
, vol.108
, pp. 851-859
-
-
Milella, M.1
Kornblau, S.M.2
Estrov, Z.3
Carter, B.Z.4
Lapillonne, H.5
Harris, D.6
-
27
-
-
1842453948
-
Combined proteasome and histone deacetylase inhibition in non-small cell lung cancer
-
C.E. Denlinger, M.D. Keller, M.W. Mayo, R.M. Broad, and D.R. Jones Combined proteasome and histone deacetylase inhibition in non-small cell lung cancer J. Thorac. Cardiovasc. Surg. 127 2004 1078 1086
-
(2004)
J. Thorac. Cardiovasc. Surg.
, vol.127
, pp. 1078-1086
-
-
Denlinger, C.E.1
Keller, M.D.2
Mayo, M.W.3
Broad, R.M.4
Jones, D.R.5
-
29
-
-
0032841577
-
Suppression of cell cycle progression by flavonoids: Dependence on the aryl hydrocarbon receptor
-
J.J. Reiners Jr., R. Clift, and P. Mathieu Suppression of cell cycle progression by flavonoids: dependence on the aryl hydrocarbon receptor Carcinogenesis 20 1999 1561 1566
-
(1999)
Carcinogenesis
, vol.20
, pp. 1561-1566
-
-
Reiners Jr., J.J.1
Clift, R.2
Mathieu, P.3
-
30
-
-
0036732169
-
Release of cytochrome c and activation of pro-caspase-9 following lysosomal photodamage involves bid cleavage
-
J.J. Reiners Jr., J.A. Caruso, P. Mathieu, B. Chelladurai, X-M. Yin, and D. Kessel Release of cytochrome c and activation of pro-caspase-9 following lysosomal photodamage involves bid cleavage Cell Death Differ. 9 2002 934 944
-
(2002)
Cell Death Differ.
, vol.9
, pp. 934-944
-
-
Reiners Jr., J.J.1
Caruso, J.A.2
Mathieu, P.3
Chelladurai, B.4
Yin, X.-M.5
Kessel, D.6
-
31
-
-
0032146095
-
Extended survivability of prostate cancer cells in the absence of trophic factors: Increased proliferation, evasion of apoptosis, and the role of apoptosis proteins
-
D.G. Tang, L. Li, D.P. Chopra, and A.T. Porter Extended survivability of prostate cancer cells in the absence of trophic factors: increased proliferation, evasion of apoptosis, and the role of apoptosis proteins Cancer Res. 58 1998 3466 3479
-
(1998)
Cancer Res.
, vol.58
, pp. 3466-3479
-
-
Tang, D.G.1
Li, L.2
Chopra, D.P.3
Porter, A.T.4
-
32
-
-
0035353163
-
Cytokine-regulated expression of survivin in myeloid leukemia
-
B.Z. Carter, M. Milella, D.C. Albert, and M. Andreeff Cytokine-regulated expression of survivin in myeloid leukemia Blood 97 2001 2784 2790
-
(2001)
Blood
, vol.97
, pp. 2784-2790
-
-
Carter, B.Z.1
Milella, M.2
Albert, D.C.3
Andreeff, M.4
-
33
-
-
0345826036
-
Acute ablation of survivin uncovers p53-dependent mitotic checkpoint functions and control of mitochondrial apoptosis
-
E. Beltrami, J. Plescia, J.C. Wilkinson, C.S. Duckett, and D.C. Altieri Acute ablation of survivin uncovers p53-dependent mitotic checkpoint functions and control of mitochondrial apoptosis J. Biol. Chem. 279 2004 2077 2084
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 2077-2084
-
-
Beltrami, E.1
Plescia, J.2
Wilkinson, J.C.3
Duckett, C.S.4
Altieri, D.C.5
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