Optimization of the binding properties of a synthetic anion receptor using rational and combinatorial strategies

Biosensors and Bioelectronics

Volumn 20, Issue 11, 2005, Pages 2364-2375

  Kubik, Stefan ^a,d   Goddard, Richard ^b   Otto, Sijbren ^c   Pohl, Susanne ^a   Reyheller, Carsten ^a   Stüwe, Sabine ^a  

^a HEINRICH HEINE UNIVERSITY   (Germany)

^b MAX PLANCK INSTITUT FÜR KOHLENFORSCHUNG   (Germany)

^c UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^d Rheinland Pfälzische Technische Universität Kaiserslautern Landau   (Germany)

Author keywords

Anion recognition; Conformational analysis; Cyclic peptides; Supramolecular chemistry; Synthetic receptors

Indexed keywords

COMPLEXATION; CONFORMATIONS; HYDROGEN BONDS; MIXTURES; NEGATIVE IONS; ORGANIC SOLVENTS;

CYCLOPEPTIDES; POLAR SOLVENTS; PROTIC SOLVENTS; SOLVENT POLARITY;

AMINO ACIDS;

6 AMINOPICOLINIC ACID; AMIDE; ANION; CHLOROFORM; CYCLOPEPTIDE; DEUTERIUM OXIDE; DIMETHYL SULFOXIDE; HEXAPEPTIDE; HYDROGEN; PICOLINIC ACID DERIVATIVE; PROLINE; PROTEIN SUBUNIT; RECEPTOR; SOLVENT; TETRAMER; UNCLASSIFIED DRUG; WATER;

ARTICLE; BINDING AFFINITY; CHEMICAL STRUCTURE; COMBINATORIAL CHEMISTRY; COMPLEX FORMATION; CONFORMATIONAL TRANSITION; COVALENT BOND; HYDROGEN BOND; MOLECULAR INTERACTION; POLARIZATION; PROTEIN CONFORMATION; PROTEIN STABILITY; RECEPTOR BINDING;

EID: 15944415696     PISSN: 09565663     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bios.2004.01.035     Document Type: Article

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