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+ iodide showed no influence of complex formation on the vibration frequencies of the peptide's carbonyl groups. We take this as a further indication that the complexation of cations by 2 is due to cation-π interactions. More importantly, we recently were able to crystallize a complex of a quaternary ammonium ion and a cyclic hexapeptide which contains L-proline subunits instead of glutamic acid. We could detect no directed hydrogen bonds between the carbonyl groups of the peptide and the ammonium ion in the crystal structure. The properties of the L-proline-containing cyclopeptide will be published shortly.
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0344776596
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+-18-crown-6 2-tosylate seems to be reasonable.
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