메뉴 건너뛰기




Volumn 122, Issue 4, 2005, Pages 479-486

Ligand-binding and signaling properties of the Ax[M1] form of Notch

Author keywords

Notch; Pattern formation; Signal transduction

Indexed keywords

JAGGED1; LIGAND; NOTCH RECEPTOR; PROTEIN ABRUPTEX M1; PROTEIN DELTA; PROTEIN DERIVATIVE; PROTEIN FRINGE; RECEPTOR PROTEIN; UNCLASSIFIED DRUG;

EID: 15944414578     PISSN: 09254773     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mod.2004.12.007     Document Type: Article
Times cited : (15)

References (45)
  • 1
    • 0029670476 scopus 로고    scopus 로고
    • Interaction between Wingless and Notch signaling pathways mediated by Dishevelled
    • J.D. Axelrod, K. Matsuno, S. Artavanis-Tsakonas, and N. Perrimon Interaction between Wingless and Notch signaling pathways mediated by Dishevelled Science 271 1996 1826 1832
    • (1996) Science , vol.271 , pp. 1826-1832
    • Axelrod, J.D.1    Matsuno, K.2    Artavanis-Tsakonas, S.3    Perrimon, N.4
  • 2
    • 0034646417 scopus 로고    scopus 로고
    • Notch signaling directly controls cell proliferation in the Drosophila wing disc
    • A. Baonza, and A. Garcia-Bellido Notch signaling directly controls cell proliferation in the Drosophila wing disc Proc. Natl Acad. Sci. 97 1999 2609 2614
    • (1999) Proc. Natl Acad. Sci. , vol.97 , pp. 2609-2614
    • Baonza, A.1    Garcia-Bellido, A.2
  • 3
    • 0037376416 scopus 로고    scopus 로고
    • An overview of the Notch signalling pathway
    • M. Baron An overview of the Notch signalling pathway Semin. Cell Dev. Biol. 14 2003 113 119
    • (2003) Semin. Cell Dev. Biol. , vol.14 , pp. 113-119
    • Baron, M.1
  • 4
    • 0028286635 scopus 로고
    • The role of apterous in the control of dorsoventral compartmentalization and PS integrin gene expression in the developing wing of Drosophila
    • S.S. Blair, D.L. Brower, J.B. Thomas, and M. Zavortink The role of apterous in the control of dorsoventral compartmentalization and PS integrin gene expression in the developing wing of Drosophila Development 120 1994 1805 1815
    • (1994) Development , vol.120 , pp. 1805-1815
    • Blair, S.S.1    Brower, D.L.2    Thomas, J.B.3    Zavortink, M.4
  • 5
    • 0030929259 scopus 로고    scopus 로고
    • A functional analysis of Notch mutations in Drosophila
    • K. Brennan, R. Tateson, K. Lewis, and A. Martinez Arias A functional analysis of Notch mutations in Drosophila Genetics 147 1997 177 188
    • (1997) Genetics , vol.147 , pp. 177-188
    • Brennan, K.1    Tateson, R.2    Lewis, K.3    Martinez Arias, A.4
  • 6
    • 0029795757 scopus 로고    scopus 로고
    • Antagonistic interactions between Wingless and Decapentaplegic responsible for dorsal-ventral pattern in the Drosophila leg
    • W.J. Brook, and S.M. Cohen Antagonistic interactions between Wingless and Decapentaplegic responsible for dorsal-ventral pattern in the Drosophila leg Science 273 1996 1373 1377
    • (1996) Science , vol.273 , pp. 1373-1377
    • Brook, W.J.1    Cohen, S.M.2
  • 7
    • 0242593940 scopus 로고    scopus 로고
    • Glycosytransferase activity of Fringe modulates Notch-Delta interactions
    • K. Brückner, L. Perez, H. Clausen, and S.M. Cohen Glycosytransferase activity of Fringe modulates Notch-Delta interactions Nature 406 2000 411 415
    • (2000) Nature , vol.406 , pp. 411-415
    • Brückner, K.1    Perez, L.2    Clausen, H.3    Cohen, S.M.4
  • 8
    • 0035923524 scopus 로고    scopus 로고
    • Fringe modulation of Jagged1-induced Notch signaling requires the action of beta 4galactosyltransferase-1
    • J. Chen, D.J. Moloney, and P. Stanley Fringe modulation of Jagged1-induced Notch signaling requires the action of beta 4galactosyltransferase-1 Proc. Natl Acad. Sci. USA 98 2001 13716 13721
    • (2001) Proc. Natl Acad. Sci. USA , vol.98 , pp. 13716-13721
    • Chen, J.1    Moloney, D.J.2    Stanley, P.3
  • 9
    • 0030776397 scopus 로고    scopus 로고
    • Feed-back mechanisms affecting Notch activation at the dorsoventral boundary in the Drosophila wing
    • J.F. de Celis, and S. Bray Feed-back mechanisms affecting Notch activation at the dorsoventral boundary in the Drosophila wing Development 124 1997 3241 3251
    • (1997) Development , vol.124 , pp. 3241-3251
    • De Celis, J.F.1    Bray, S.2
  • 10
    • 0034038237 scopus 로고    scopus 로고
    • The Abruptex domain of Notch regulates negative interactions between Notch, its ligands and Fringe
    • J.F. de Celis, and S. Bray The Abruptex domain of Notch regulates negative interactions between Notch, its ligands and Fringe Development 127 2000 1291 1302
    • (2000) Development , vol.127 , pp. 1291-1302
    • De Celis, J.F.1    Bray, S.2
  • 11
    • 0028082218 scopus 로고
    • Modifications of Notch function by Abruptex mutations in Drosophila melanogaster
    • J.F. de Celis, and A. Garcia-Bellido Modifications of Notch function by Abruptex mutations in Drosophila melanogaster Genetics 136 1994 183 194
    • (1994) Genetics , vol.136 , pp. 183-194
    • De Celis, J.F.1    Garcia-Bellido, A.2
  • 12
    • 0027192017 scopus 로고
    • Genetic and molecular characterization of a Notch mutation in its Delta and Serrate binding domain in Drosophila
    • J.F. de Celis, R. Barrio, A. del Arco, and A. Garcia-Bellido Genetic and molecular characterization of a Notch mutation in its Delta and Serrate binding domain in Drosophila Proc. Natl Acad. Sci. 90 1993 4037 4041
    • (1993) Proc. Natl Acad. Sci. , vol.90 , pp. 4037-4041
    • De Celis, J.F.1    Barrio, R.2    Del Arco, A.3    Garcia-Bellido, A.4
  • 13
    • 0029819667 scopus 로고    scopus 로고
    • Functional relationships between Notch, Su(H) and the bHLH genes of the E(spl) complex: The E(spl) genes mediate only a subset of Notch activities during imaginal development
    • J.F. de Celis, J. de Celis, P. Ligoxygakis, A. Preiss, C. Delidakis, and S. Bray Functional relationships between Notch, Su(H) and the bHLH genes of the E(spl) complex: the E(spl) genes mediate only a subset of Notch activities during imaginal development Development 122 1996 2719 2728
    • (1996) Development , vol.122 , pp. 2719-2728
    • De Celis, J.F.1    De Celis, J.2    Ligoxygakis, P.3    Preiss, A.4    Delidakis, C.5    Bray, S.6
  • 14
    • 0027504573 scopus 로고
    • Interaction between dorsal and ventral cells in the imaginal disc directs wing development in Drosophila
    • F.J. Diaz-Benjumea, and S.M. Cohen Interaction between dorsal and ventral cells in the imaginal disc directs wing development in Drosophila Cell 75 1993 741 752
    • (1993) Cell , vol.75 , pp. 741-752
    • Diaz-Benjumea, F.J.1    Cohen, S.M.2
  • 15
    • 0029585601 scopus 로고
    • Serrate signals through Notch to establish a Wingless-dependent organizer at the dorsal/ventral compartment boundary of the Drosophila wing
    • F.J. Diaz-Benjumea, and S.M. Cohen Serrate signals through Notch to establish a Wingless-dependent organizer at the dorsal/ventral compartment boundary of the Drosophila wing Development 121 1995 4215 4225
    • (1995) Development , vol.121 , pp. 4215-4225
    • Diaz-Benjumea, F.J.1    Cohen, S.M.2
  • 16
    • 0029960107 scopus 로고    scopus 로고
    • Dorsal and ventral cells respond differently to the Notch ligands Delta and Serrate during Drosophila wing development
    • D. Doherty, G. Fenger, S. Younger-Shepherd, L.-Y. Jan, and Y.-N. Jan Dorsal and ventral cells respond differently to the Notch ligands Delta and Serrate during Drosophila wing development Genes Dev. 10 1996 421 434
    • (1996) Genes Dev. , vol.10 , pp. 421-434
    • Doherty, D.1    Fenger, G.2    Younger-Shepherd, S.3    Jan, L.-Y.4    Jan, Y.-N.5
  • 17
    • 0030845799 scopus 로고    scopus 로고
    • Serrate-mediated activation of Notch is specifically blocked by the product of the gene fringe in the dorsal compartment of the Drosophila wing imaginal disc
    • R.J. Fleming, Y. Gu, and N.A. Hukriede Serrate-mediated activation of Notch is specifically blocked by the product of the gene fringe in the dorsal compartment of the Drosophila wing imaginal disc Development 124 1997 2973 2981
    • (1997) Development , vol.124 , pp. 2973-2981
    • Fleming, R.J.1    Gu, Y.2    Hukriede, N.A.3
  • 18
    • 0036727125 scopus 로고    scopus 로고
    • Gamma-secretase-mediated proteolysis in cell-surface-receptor signalling
    • M.E. Fortini Gamma-secretase-mediated proteolysis in cell-surface- receptor signalling Nat. Rev. Mol. Cell Biol. 3 2002 673 684
    • (2002) Nat. Rev. Mol. Cell Biol. , vol.3 , pp. 673-684
    • Fortini, M.E.1
  • 19
    • 0035177388 scopus 로고    scopus 로고
    • A model Notch response element detects Suppressor of Hairless-dependent molecular switch
    • M. Furriols, and S. Bray A model Notch response element detects Suppressor of Hairless-dependent molecular switch Curr. Biol. 11 2001 60 64
    • (2001) Curr. Biol. , vol.11 , pp. 60-64
    • Furriols, M.1    Bray, S.2
  • 20
    • 0347765662 scopus 로고    scopus 로고
    • Wingless and Notch signaling provide cell survival cues and control cell proliferation during wing development
    • A.J. Giraldez, and S.M. Cohen Wingless and Notch signaling provide cell survival cues and control cell proliferation during wing development Development 130 2003 6533 6543
    • (2003) Development , vol.130 , pp. 6533-6543
    • Giraldez, A.J.1    Cohen, S.M.2
  • 21
    • 0027536121 scopus 로고
    • Altered epidermal growth factor-like sequences provide evidence for a role of Notch as a receptor in cell fate decisions
    • P. Heitzler, and P. Simpson Altered epidermal growth factor-like sequences provide evidence for a role of Notch as a receptor in cell fate decisions Development 117 1993 1113 1123
    • (1993) Development , vol.117 , pp. 1113-1123
    • Heitzler, P.1    Simpson, P.2
  • 23
    • 0027945519 scopus 로고
    • Fringe, a boundary specific signalling molecule, mediates interactions between dorsal and ventral cells during Drosophila wing development
    • K. Irvine, and E. Wieschaus fringe, a boundary specific signalling molecule, mediates interactions between dorsal and ventral cells during Drosophila wing development Cell 79 1994 595 606
    • (1994) Cell , vol.79 , pp. 595-606
    • Irvine, K.1    Wieschaus, E.2
  • 24
    • 0041689540 scopus 로고    scopus 로고
    • Wingless promotes cell survival but constrains growth during Drosophila wing development
    • L.A. Johnston, and A.L. Sanders Wingless promotes cell survival but constrains growth during Drosophila wing development Nat. Cell Biol. 5 2003 827 833
    • (2003) Nat. Cell Biol. , vol.5 , pp. 827-833
    • Johnston, L.A.1    Sanders, A.L.2
  • 25
    • 0030744231 scopus 로고    scopus 로고
    • A family of mammalian Fringe genes implicated in boundary determination and the Notch pathway
    • S.H. Johnston, C. Rauskolb, R. Wilson, B. Prabhakaran, K.D. Irvine, and T.F. Vogt A family of mammalian Fringe genes implicated in boundary determination and the Notch pathway Development 124 1997 2245 2254
    • (1997) Development , vol.124 , pp. 2245-2254
    • Johnston, S.H.1    Rauskolb, C.2    Wilson, R.3    Prabhakaran, B.4    Irvine, K.D.5    Vogt, T.F.6
  • 27
    • 0029093437 scopus 로고
    • Cell recognition, signal induction and symmetrical gene activation at the dorsal/ventral boundary of the developing Drosophila wing
    • J. Kim, K.D. Irvine, and S.B. Carroll Cell recognition, signal induction and symmetrical gene activation at the dorsal/ventral boundary of the developing Drosophila wing Cell 82 1995 795 802
    • (1995) Cell , vol.82 , pp. 795-802
    • Kim, J.1    Irvine, K.D.2    Carroll, S.B.3
  • 28
    • 0031238781 scopus 로고    scopus 로고
    • An intrinsic dominant negative activity of serrate that is modulated during wing development in Drosophila
    • T. Klein, K. Brennan, and A.M. Arias An intrinsic dominant negative activity of serrate that is modulated during wing development in Drosophila Dev. Biol. 189 1997 123 134
    • (1997) Dev. Biol. , vol.189 , pp. 123-134
    • Klein, T.1    Brennan, K.2    Arias, A.M.3
  • 29
    • 0027954477 scopus 로고
    • The Drosophila segment polarity gene dishevelled encodes a novel protein required for response to the wingless signal
    • J. Klingensmith, R. Nusse, and N. Perrimon The Drosophila segment polarity gene dishevelled encodes a novel protein required for response to the wingless signal Genes Dev. 8 1994 118 130
    • (1994) Genes Dev. , vol.8 , pp. 118-130
    • Klingensmith, J.1    Nusse, R.2    Perrimon, N.3
  • 30
    • 0026495506 scopus 로고
    • Single amino acid substitutions in EGF-like elements of Notch and Delta modify Drosophila development and affect cell adhesion in vitro
    • T. Lieber, C.S. Wesley, E. Alcamo, B. Hassel, J.F. Krane, J.A. Campos-Ortega, and M.W. Young Single amino acid substitutions in EGF-like elements of Notch and Delta modify Drosophila development and affect cell adhesion in vitro Neuron 9 1992 847 859
    • (1992) Neuron , vol.9 , pp. 847-859
    • Lieber, T.1    Wesley, C.S.2    Alcamo, E.3    Hassel, B.4    Krane, J.F.5    Campos-Ortega, J.A.6    Young, M.W.7
  • 31
    • 0030918403 scopus 로고    scopus 로고
    • The function and regulation of cut expression on the wing margin of Drosophila: Notch, Wingless and a dominant negative role for Delta and Serrate
    • C.A. Micchelli, E.J. Rulifson, and S.S. Blair The function and regulation of cut expression on the wing margin of Drosophila: Notch, Wingless and a dominant negative role for Delta and Serrate Development 124 1997 1485 1495
    • (1997) Development , vol.124 , pp. 1485-1495
    • Micchelli, C.A.1    Rulifson, E.J.2    Blair, S.S.3
  • 33
    • 0029960417 scopus 로고    scopus 로고
    • A hierarchy of cross-regulation involving Notch, wingless, vestigial and cut organizes the dorsal/ventral axis of the Drosophila wing
    • C.J. Neumann, and S.M. Cohen A hierarchy of cross-regulation involving Notch, wingless, vestigial and cut organizes the dorsal/ventral axis of the Drosophila wing Development 122 1996 3477 3485
    • (1996) Development , vol.122 , pp. 3477-3485
    • Neumann, C.J.1    Cohen, S.M.2
  • 34
    • 0032540875 scopus 로고    scopus 로고
    • Boundary formation in the Drosophila wing: The POU-domain protein Nubbin attenuates Notch activity
    • C.J. Neumann, and S.M. Cohen Boundary formation in the Drosophila wing: the POU-domain protein Nubbin attenuates Notch activity Science 281 1998 409 413
    • (1998) Science , vol.281 , pp. 409-413
    • Neumann, C.J.1    Cohen, S.M.2
  • 35
    • 0028176875 scopus 로고
    • Dishevelled and armadillo act in the Wingless signalling pathway in Drosophila
    • J. Noordermeer, J. Klingensmith, N. Perrimon, and R. Nusse dishevelled and armadillo act in the Wingless signalling pathway in Drosophila Nature 367 1994 80 83
    • (1994) Nature , vol.367 , pp. 80-83
    • Noordermeer, J.1    Klingensmith, J.2    Perrimon, N.3    Nusse, R.4
  • 36
    • 0037074006 scopus 로고    scopus 로고
    • Regulation of notch signaling by o-linked fucose
    • T. Okajima, and K.D. Irvine Regulation of notch signaling by o-linked fucose Cell 111 2002 893 904
    • (2002) Cell , vol.111 , pp. 893-904
    • Okajima, T.1    Irvine, K.D.2
  • 37
    • 0141922141 scopus 로고    scopus 로고
    • Modulation of notch-ligand binding by protein O-fucosyltransferase 1 and fringe
    • T. Okajima, A. Xu, and K.D. Irvine Modulation of notch-ligand binding by protein O-fucosyltransferase 1 and fringe J. Biol. Chem. 278 2003 42340 42345
    • (2003) J. Biol. Chem. , vol.278 , pp. 42340-42345
    • Okajima, T.1    Xu, A.2    Irvine, K.D.3
  • 39
    • 0026086474 scopus 로고
    • Specific EGF repeats of Notch mediate interactions with Delta and Serrate: Implications for Notch as a multifunctional receptor
    • I. Rebay, R.J. Fleming, R.G. Fehon, L. Cherbas, P. Cherbas, and S. Artavanis-Tsakonas Specific EGF repeats of Notch mediate interactions with Delta and Serrate: implications for Notch as a multifunctional receptor Cell 67 1991 687 699
    • (1991) Cell , vol.67 , pp. 687-699
    • Rebay, I.1    Fleming, R.J.2    Fehon, R.G.3    Cherbas, L.4    Cherbas, P.5    Artavanis-Tsakonas, S.6
  • 40
    • 0029080346 scopus 로고
    • Notch regulates wingless expression and is not required for reception of the paracrine wingless signal during wing margin neurogenesis in Drosophila
    • E.J. Rulifson, and S.S. Blair Notch regulates wingless expression and is not required for reception of the paracrine wingless signal during wing margin neurogenesis in Drosophila Development 121 1995 2813 2824
    • (1995) Development , vol.121 , pp. 2813-2824
    • Rulifson, E.J.1    Blair, S.S.2
  • 41
    • 0029904837 scopus 로고    scopus 로고
    • Wingless refines its own expression domain on the Drosophila wing margin
    • E.J. Rulifson, C.A. Micchelli, J.D. Axelrod, N. Perrimon, and S.S. Blair wingless refines its own expression domain on the Drosophila wing margin Nature 384 1996 72 74
    • (1996) Nature , vol.384 , pp. 72-74
    • Rulifson, E.J.1    Micchelli, C.A.2    Axelrod, J.D.3    Perrimon, N.4    Blair, S.S.5
  • 42
    • 0037081076 scopus 로고    scopus 로고
    • Intracellular cell-autonomous association of Notch and its ligands: A novel mechanism of Notch signal modification
    • K. Sakamoto, O. Ohara, M. Takagi, S. Takeda, and K. Katsube Intracellular cell-autonomous association of Notch and its ligands: a novel mechanism of Notch signal modification Dev. Biol. 241 2002 313 326
    • (2002) Dev. Biol. , vol.241 , pp. 313-326
    • Sakamoto, K.1    Ohara, O.2    Takagi, M.3    Takeda, S.4    Katsube, K.5
  • 43
    • 0041355557 scopus 로고    scopus 로고
    • Notch and Presenilin: Regulated intramembrane proteolysis links development and degeneration
    • D. Selkoe, and R. Kopan Notch and Presenilin: regulated intramembrane proteolysis links development and degeneration Annu. Rev. Neurosci. 26 2003 565 597
    • (2003) Annu. Rev. Neurosci. , vol.26 , pp. 565-597
    • Selkoe, D.1    Kopan, R.2
  • 44
    • 0037424256 scopus 로고    scopus 로고
    • Fringe modifies O-fucose on mouse Notch1 at epidermal growth factor-like repeats within the ligand-binding site and the Abruptex region
    • L. Shao, D.J. Moloney, and R. Haltiwanger Fringe modifies O-fucose on mouse Notch1 at epidermal growth factor-like repeats within the ligand-binding site and the Abruptex region J. Biol. Chem. 278 2003 7775 7782
    • (2003) J. Biol. Chem. , vol.278 , pp. 7775-7782
    • Shao, L.1    Moloney, D.J.2    Haltiwanger, R.3
  • 45
    • 0035199155 scopus 로고    scopus 로고
    • Regulation of Apterous activity in Drosophila wing development
    • U. Weihe, M. Milan, and S.M. Cohen Regulation of Apterous activity in Drosophila wing development Development 128 2001 4615 4622
    • (2001) Development , vol.128 , pp. 4615-4622
    • Weihe, U.1    Milan, M.2    Cohen, S.M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.