Behavior of diphtheria toxin T domain containing substitutions that block normal membrane insertion at Pro345 and Leu307: Control of deep membrane insertion and coupling between deep insertion of hydrophobic subdomains

Biochemistry

Volumn 44, Issue 11, 2005, Pages 4488-4498

  Zhao, Gang ^a   London, Erwin ^a  

^a NONE

Author keywords

[No Author keywords available]

Indexed keywords

FLUORESCENCE; HYDROPHOBICITY; LIPIDS; SUBSTITUTION REACTIONS; TOXICITY;

DIPTHERIA TOXIN; NONTRANSMEMBRANE STRUCTURE; PORE FORMATION; TRANSMEMBRANE HAIRPIN;

BIOLOGICAL MEMBRANES;

ASPARAGINE; BIOTIN; DIPHTHERIA TOXIN; DIPHTHERIA TOXIN A CHAIN; GLUTAMIC ACID; GLYCINE; LEUCINE; PROLINE; STREPTAVIDIN; UNCLASSIFIED DRUG;

AMINO ACID SUBSTITUTION; ARTICLE; BIOASSAY; CHANNEL GATING; FLUORESCENCE; LIPID BILAYER; LIPID MEMBRANE; MUTATION; PRIORITY JOURNAL; PROTEIN DOMAIN; TOXICITY; TOXIN ANALYSIS; TOXIN STRUCTURE;

AMINO ACID SUBSTITUTION; BORON COMPOUNDS; DIPHTHERIA TOXIN; DNA MUTATIONAL ANALYSIS; FLUORESCENT DYES; HYDROPHOBICITY; LEUCINE; LIPID BILAYERS; MEMBRANE PROTEINS; MUTAGENESIS, SITE-DIRECTED; PROLINE; PROTEIN CONFORMATION; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; PROTEIN TRANSPORT; SPECTROMETRY, FLUORESCENCE;

EID: 15544385169     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi047705o     Document Type: Article

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