IL-12 or IL-4 prime human NK cells to mediate functionally divergent interactions with dendritic cells or tumors

Journal of Immunology

Volumn 174, Issue 7, 2005, Pages 3992-3998

  Marcenaro, Emanuela ^a   Della Chiesa, Mariella ^a   Bellora, Francesca ^b   Parolini, Silvia ^c   Millo, Romano ^a   Moretta, Lorenzo ^a,b   Moretta, Alessandro ^a  

^a UNIVERSITY OF GENOA   (Italy)

^b G GASLINI INSTITUTE   (Italy)

^c UNIVERSITY OF BRESCIA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERLEUKIN 12; INTERLEUKIN 13; INTERLEUKIN 4; INTERLEUKIN 5; TUMOR NECROSIS FACTOR ALPHA;

ANTINEOPLASTIC ACTIVITY; ARTICLE; BLOOD CELL; BONE MARROW CELL; CELL CULTURE; CELL INTERACTION; CELL KILLING; CELL MATURATION; CELL STIMULATION; CELL SURFACE; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; CYTOLYSIS; DENDRITIC CELL; HUMAN; HUMAN CELL; INCUBATION TIME; NATURAL KILLER CELL; PRIORITY JOURNAL; PROTEIN ANALYSIS; TUMOR CELL;

EID: 15444363620     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.174.7.3992     Document Type: Article

References (47)

1. Moretta, A. 2002. Natural killer cells and dendritic cells: rendezvous in abused tissues. Nat. Rev. Immunol. 2 957.
2. Zitvogel, L. 2002. Dendritic and natural killer cells cooperate in the control/switch of innate immunity. J. Exp. Med. 195:9.
3. Cooper, M. A., T. A. Fehniger, A. Fuchs, M. Colonna, and M. A. Caligiuri. 2004. NK cell and DC interactions. Trends Immunol. 25:47.
4. Ferlazzo, G., M. L. Tsang, L. Moretta, G. Melioli, R. M. Steinman, and C. Munz. 2002. Human dendritic cells activate resting natural killer (NK) cells and are recognized via the NKp30 receptor by activated NK cells. J. Exp. Med. 195:343.
5. Piccioli, D., S. Sbrana, E. Melandri, and N. M. Valiante. 2002. Contact-dependent stimulation and inhibition of dendritic cells by natural killer cells. J. Exp. Med. 195:335.
6. Gerosa, F., B. Baldani-Guerra, C. Nisii, V. Marchesini, G. Carra, and G. Trinchieri. 2002. Reciprocal activating interaction between NK cells and dendritic cells. J. Exp. Med. 195:327.
7. Della Chiesa, M., M. Vitale, S. Carlomagno, G. Ferlazzo, L. Moretta, and A. Moretta. 2003. The natural killer cell mediated killing of autologous dendritic cells is confined to a cell subset expressing CD94/NKG2A, but lacking inhibitory killer Ig-like receptors. Eur. J. Immunol. 33:1657.
8. - natural killer cells is selectively responsible for both cell proliferation and interferon-γ production upon interaction with dendritic cells. Eur. J. Immunol. 34:1715.
9. Wilson, J. L., L. C. Heffler, J. Charo, A. Scheynius, M. T. Bejarano, and H. G. Ljunggren. 1999. Targeting of human dendritic cells by autologous NK cells. J. Immunol. 163:6365.
10. Sivori, S., M. Falco, M. Della Chiesa, S. Carlomagno, M. Vitale, L. Moretta, and A. Moretta. 2004. CpG and double-stranded RNA trigger human NK cells by Toll-like receptors: induction of cytokine release and cytotoxicity against tumors and dendritic cells. Proc. Natl. Acad. Sci. USA 101:10116.
11. Martin-Fontecha, A., L. L. Thomsen, S. Brett, C. Gerard, M. Lipp, A. Lanzavecchia, and F. Sallusto. 2004. Induced recruitment of NK cells to lymph nodes provides IFN-γ for Th1 priming. Nat. Immunol. 5:1260.
12. Peritt, D., S. Robertson, G. Gri, L. Showe, M. Aste-Amezaga, and G. Trinchieri. 1998. Differentiation of human NK cells into NK1 and NK2 subsets. J. Immunol. 161:5821.
13. Deniz, G., M. Akdis, E. Aktas, K. Blaser, and C. A. Akdis. 2002. Human NK1 and NK2 subsets determined by purification of IFN-γ-secreting and IFN-γ-non-secreting NK cells. Eur. J. Immunol. 32:879.
14. Janeway, C. A., Jr., and R. Medzhitov. 2002. Innate immune recognition. Annu. Rev. Immunol. 20:197.
15. Medzhitov, R., and C. A. Janeway, Jr. 1999. Innate immune induction of the adaptive immune response. Cold Spring Harb. Symp. Quant. Biol. 64:429.
16. Loza, M. J., and B. Perussia. 2001. Final step of natural killer cell maturation: a model for type 1-type 2 differentiation? Nat. Immunol. 2:917.
17. Loza, M. J., L. Zamai, L. Azzoni, E. Rosati, and B. Perussia. 2002. Expression of type 1 (interferon γ) and type 2 (interleukin-13, interleukin-5) cytokines at distinct stages of natural killer cell differentiation. Blood 99:1273.
18. + natural killer cells and regulation of their pool size by IL-4. Eur. J. Immunol. 32:413.
19. Liu, Y. J., N. Kadowak, M. C. Rissoan, and V. Soumelis. 2000. T cell activation and polarization by DC1 and DC2. Curr. Top. Microbiol. Immunol. 25:149.
20. Ito, T., R. Amakawa, M. Inaba, T. Hori, M. Ota, K. Nakamura, M. Takebayashi, M. Miyaji, T. Yoshimura, K. Inaba, et al. 2004. Plasmacytoid dendritic cells regulate Th cell responses through OX40 ligand and type I IFNs. J. Immunol. 172:4253.
21. Romani, L. 2004. Immunity to fungal infections. Nat. Rev. Immunol. 4:1.
22. Langenkamp, A., M. Messi, A. Lanzavecchia, and F. Sallusto. 2000. Kinetic of dendritic cell activation: impact on priming of TH1, TH2 and nonpolarized T cells. Nat. Immunol. 1:311.
23. Biron, C. A., K. B. Nguyen, G. C. Pien, L. P. Cousens, and T. P. Salazar-Mather. 1999. Natural killer cells in antiviral defense: function and regulation by innate cytokines. Annu. Rev. Immunol. 17:189.
24. + T cell responses: the alternative approaches. Annu. Rev. Immunol. 15:297.
25. Marcenaro, E., R. Augugliaro, M. Falco, R. Castriconi, S. Parolini, S. Sivori, E. Romeo, R. Millo, L. Moretta, C. Bottino, et al. 2003. CD59 is physically and functionally associated with natural cytotoxicity receptors and activates human NK cell-mediated cytotoxicity. Eur. J. Immunol. 33:3367.
26. Moretta, A., C. Bottino, M. Vitale, D. Pende, C. Cantoni, M.C. Mingari, R. Biassoni, and L. Moretta. 2001. Activating receptors and co-receptors involved in human natural killer cell-mediated cytolysis. Annu. Rev. Immunol. 19:197.
27. Cooper, M. A., T. A Fehniger, and M. A Caligiuri. 2001. The biology of human natural killer-cell subsets. Trends Immunol. 22:633.
28. Chan, S. H., B. Perussia, J. W. Gupta, M. Kobayashi, M. Pospisil, H. A. Young, S. F. Wolf, D. Young, S. C. Clark, and G. Trinchieri. 1991. Induction of interferon γ production by natural killer cell stimulatory factor: characterization of the responder cells and synergy with other inducers. J. Exp. Med. 173:869.
29. Nagler, A., L. L. Lanier, and J. H. Phillips. 1988. The effects of IL-4 on human natural killer cells: a potent regulator of IL-2 activation and proliferation. J. Immunol. 141:2349.
30. Moretta, L., C. Bottino, D. Pende, M. Vitale, M. C. Mingari, and A. Moretta. 2004. Different checkpoints in NK cell activation. Trends Immunol. 25:670.
31. Ferlazzo, G., D. Thomas, S. L. Lin, K. Goodman, B. Morandi, W. A. Muller, A. Moretta, and C. Munz. 2004. The abundant NK cells in human secondary lymphoid tissues require activation to express killer cell Ig-like receptors and become cytolytic. J. Immunol. 172:1455.
32. Ferlazzo, G., and C. Munz. 2004. NK cell compartments and their activation by dendritic cells. J. Immunol. 172:1333.
33. Banchereau, J., and R. M. Steinman. 1998. Dendritic cells and the control of immunity. Nature 392:245.
34. Banchereau, J., F. Briere, C. Caux, J. Davoust, S. Lebecque, Y. J. Liu, B. Pulendran, and K. Palucka. 2000. Immunobiology of dendritic cells. Annu. Rev. Immunol. 18: 767.
35. Sallusto, F., and A. Lanzavecchia. 1999. Mobilizing dendritic cells for tolerance, priming, and chronic inflammation. J. Exp. Med. 189:611.
36. - dendritic cell activation status plays an integral role in influencing Th2 response development. J. Immunol. 167:1982.
37. d'Ostiani, C. F., G. Del Sero, A. Bacci, C. Montagnoli, A. Spreca, A. Mencacci, P. Ricciardi-Castagnoli, and L. Romani. 2000. Dendritic cells discriminate between yeasts and hyphae of the fungus Candida albicans: implications for initiation of T helper cell immunity in vitro and in vivo. J. Exp. Med. 191:1661.
38. Pulendran, B., P. Kumar, C. W. Cutler, M. Mohamadzadeh, T. Van Dyke, and J. Banchereau. 2001. Lipopolysaccharides from distinct pathogens induce different classes of immune responses in vivo. J. Immunol. 167:5067.
39. bright subset. Blood 97:3146.
40. Mailliard, R. B., Y. I. Son, R. Redlinger, P. T. Coates, A. Giermasz, P. A. Morel, W. J. Storkus, and P. Kalinski. 2003. Dendritic cells mediate NK cell help for Th1 and CTL responses: two-signal requirement for the induction of NK cell helper function. J. Immunol. 171:2366.
41. Byrne, P., P. McGuirk, S. Todryk, and K. H. G. Mills. 2004. Depletion of NK cells results in disseminating lethal infection with Bordetella pertussis associated with a reduction of antigen-specific Th1 and enhancement of Th2, but not Tr1. Eur. J. Immunol. 34:2579.
42. Lanzavecchia, A., and F. Sallusto. 2001. The instructive role of dendritic cells on T cell responses: lineages, plasticity and kinetics. Curr. Opin. Immunol. 13:291.
43. bright natural killer cells are present in human lymph nodes and are activated by T cell-derived IL-2: a potential new link between adaptive and innate immunity. Blood 101:3052.
44. de Vries, E., H. R. Koene, J. M. Vossen, J. W. Gratama, A. E. von dem Borne, J. L. Waaijer, A. Haraldsson, M. de Haas, and M. J. van Tol. 1996. Identification of an unusual Fcγ receptor IIIa (CD16) on natural killer cells in a patient with recurrent infections. Blood 88:3022.
45. Biron, C. A., K. S. Byron, and J. L. Sullivan. 1989. Severe herpesvirus infections in an adolescent without natural killer cells. N. Engl. J. Med. 320:1731.
46. Doherty, P. C., and J. E. Allan. 1987. Anti-asialo GM1 eliminates both inflammatory process and cytotoxic T-cell function in the lymphocytic choriomeningitis adoptive transfer model. Cell. Immunol. 107:1.
47. Coudert, J. D., C. Coureau, and J. C. Guery. 2002. Preventing NK cell activation by donor dendritic cells enhances allospecific CD4 T cell priming and promotes Th type 2 responses to transplantation antigens. J. Immunol. 169:2979.