Ubc9 interacts with chicken ovalbumin upstream promoter-transcription factor I and represses receptor-dependent transcription

Journal of Molecular Endocrinology

Volumn 32, Issue 1, 2004, Pages 69-86

  Kobayashi, S ^a   Shibata, Hirotaka ^a   Kurihara, I ^a   Yokota, K ^a   Suda, N ^a   Saito, I ^a   Saruta, T ^a  

^a KEIO UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CHICKEN OVALBUMIN UPSTREAM PROMOTER TRANSCRIPTION FACTOR; COMPLEMENTARY DNA; GLUTATHIONE TRANSFERASE; PROTEIN UBC9; STEROID 17ALPHA MONOOXYGENASE; SUMO 1 PROTEIN;

ADRENAL CORTEX ADENOMA; AMINO ACID SEQUENCE; ANIMAL CELL; ARTICLE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; DNA BINDING; DNA LIBRARY; ENZYME ACTIVITY; FLUORESCENCE ANALYSIS; GENE CONSTRUCT; GENE IDENTIFICATION; GENE OVEREXPRESSION; GENE REPRESSION; GENETIC CODE; GENETIC TRANSFECTION; HUMAN; HUMAN TISSUE; IMMUNOPRECIPITATION; MONKEY; NERVOUS SYSTEM DEVELOPMENT; NONHUMAN; NORTHERN BLOTTING; ORGANOGENESIS; PRIORITY JOURNAL; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; REGULATORY MECHANISM; STATISTICAL ANALYSIS; TRANSCRIPTION REGULATION; WESTERN BLOTTING; YEAST;

ANIMALS; CELL NUCLEUS; CERCOPITHECUS AETHIOPS; COS CELLS; COUP TRANSCRIPTION FACTORS; DNA-BINDING PROTEINS; GENE LIBRARY; MUTATION; PROMOTER REGIONS (GENETICS); RECEPTORS, STEROID; STEROID 17-ALPHA-HYDROXYLASE; SUMO-1 PROTEIN; TISSUE DISTRIBUTION; TRANSCRIPTION FACTORS; TWO-HYBRID SYSTEM TECHNIQUES; UBIQUITIN-CONJUGATING ENZYMES;

EID: 1542360838     PISSN: 09525041     EISSN: None     Source Type: Journal    
DOI: 10.1677/jme.0.0320069     Document Type: Article

References (72)

1. Achatz G, Holzl B, Speckmayer R, Hauser C, Sandhofer F & Paulweber B 1997 Functional domains of the human orphan receptor ARP-1/COUP-TFII involved in active repression and transrepression. Molecular and Cellular Biology 17 4914-4932.
2. Avram, D, Fields A, Pretty On Top K, Nevrivy DJ, Ishmael JE & Leid M 2000 Isolation of a novel family of C(2)H(2) zinc finger proteins implicated in transcriptional repression mediated by chicken ovalbumin upstream promoter transcription factor (COUP-TF) orphan nuclear receptors. Journal of Biological Chemistry 275 10315-10322.
3. Bailey PJ, Dowhan DH, Franke K, Burke LJ, Downes M & Muscat GE 1997 Transcriptional repression by COUP-TF II is dependent on the C-terminal domain and involves the N-CoR variant, RIP13 delta1. Journal of Steroid Biochemistry and Molecular Biology 63 165-174.
4. Bakke M & Lund J 1995 Mutually exclusive interactions of two nuclear orphan receptors determine activity of a cyclic adenosine 3′,5′-monophosphate-responsive sequence in the bovine CYP17 gene. Molecular Endocrinology 9 327-339.
5. Berrodin TJ, Marks MS, Ozato K, Linney E & Lazar MA 1992 Heterodimerization among thyroid hormone receptor, retinoic acid receptor, retinoid X receptor, chicken ovalbumin upstream promoter transcription factor, and an endogenous liver protein. Molecular Endocrinology 6 1468-1478.
6. Casanova J, Helmer E, Selmi-Ruby S, Qi JS, Au-Fliegner M, Desai-Yajnik V, Koudinova N, Yarm F, Raaka BM & Samuels HH 1994 Functional evidence for ligand-dependent dissociation of thyroid hormone and retinoic acid receptors from an inhibitory cellular factor. Molecular and Cellular Biology 14 5756-5765.
7. Chakrabarti SR, Sood R, Ganguly 8, Bohlander S, Shen Z & Nucifora G 1999 Modulation of TEL transcription activity by interaction with the ubiquitin-conjugating enzyme UBC9. Proceedings of the National Academy of Sciences of the United States of America 96 7467-7472.
8. Cooney AJ, Tsai SY, O'Malley BW & Tsai MJ 1992 Chicken ovalbumin upstream promoter transcription factor (COUP-TF) dimers bind to different GGTCA response elements, allowing COUP-TF to repress hormonal induction of the vitamin D3, thyroid hormone, and retinoic acid receptors. Molecular and Cellular Biology 12 4153-4163.
9. Cooney AJ, Leng X, Tsai SY, O'Malley BW & Tsai MJ 1993 Multiple mechanisms of chicken ovalbumin upstream promoter transcription factor-dependent repression of transactivation by the vitamin D, thyroid hormone, and retinoic acid receptors. Journal of Biological Chemistry 268 4152-4160.
10. Cooney AJ, Lee CT, Lin SC, Tsai SY & Tsai MJ 2001 Physiological function of the orphans GCNF and COUP-TF. Trends in Endocrinology and Metabolism 12 247-251.
11. David G, Neptune MA & DePinho RA 2002 SUMO-1 modification of histone deacetylase 1 (HDAC1) modulates its biological activities. Journal of Biological Chemistry 277 23658-23663.
12. Desterro, JM, Rodriguez MS & Hay RT 1998 SUMO-1 modification of IkappaBalpha inhibits NF-kappaB activation. Molecular Cell 2 233-239.
13. Dressel U, Thormeyer D, Altincicek B, Paululat A, Eggert M, Schneider S, Tenbaum SP, Renkawitz R & Baniahmad A 1999 Alien, a highly conserved protein with characteristics of a corepressor for members of the nuclear hormone receptor superfamily. Molecular and Cellular Biology 19 3383-3394.
14. Durfee T, Becherer K, Chen PL, Yeh SH, Yang Y, Kilburn AE, Lee WH & Elledge SJ 1993 The retinoblastoma protein associates with the protein phosphatase type 1 catalytic subunit. Genes and Development 7 555-569.
15. Goodson ML, Hong Y, Rogers R, Matunis MJ, Park-Sarge OK & Sarge KD 2001 Sumo-1 modification regulates the DNA binding activity of heat shock transcription factor 2, a promyelocytic leukemia nuclear body associated transcription factor. Journal of Biological Chemistry 276 18513-18518.
16. Gottlicher M, Heck S, Doucas V, Wade E, Kullmann M, Cato AC, Evans RM & Herrlich P 1996 Interaction of the Ubc9 human homologue with c-Jun and with the glucocorticoid receptor. Steroids 61 257-262.
17. Hardeland U, Steinacher R, Jiricny J & Schar P 2002 Modification of the human thymine-DNA glycosylase by ubiquitin-like proteins facilitates enzymatic turnover. EMBO Journal 21 1456-1464.
18. Hay RT 2001 Protein modification by SUMO. Trends in Biochemical Sciences 26 332-333.
19. Hayashi T, Seki M, Maeda D, Wang W, Kawabe Y, Seki T, Saitoh H, Fukagawa T, Yagi H & Enomoto T 2002 Ubc9 is essential for viability of higher eukaryotic cells. Experimental Cell Research 280 212-221.
20. Hermanson O, Glass CK & Rosenfeld MG 2002 Nuclear receptor coregulators: multiple modes of modification. Trends in Endocrinology and Metabolism 13 55-60.
21. Hochstrasser M 2001 Sp-ring for SUMO. New functions bloom for a ubiquitin-like protein. Cell 107 5-8.
22. Hoege C, Pfander B, Moldovan GL, Pyrowolakis G & Jentsch S 2002 RAD6-dependent DNA repair is linked to modification of PCNA by ubiquitin and SUMO. Nature 419 135-141.
23. Huang N, vom Baur E, Garnier JM, Lerouge T, Vonesch JL, Lutz Y, Chambon P & Losson R 1998 Two distinct nuclear receptor interaction domains in NSD1, a novel SET protein that exhibits characteristics of both corepressors and coactivators. EMBO Journal 17 3398-3412.
24. Huang SM & Stallcup MR 2000 Mouse Zac1, a transcriptional coactivator and repressor for nuclear receptors. Molecular and Cellular Biology 20 1855-1867.
25. Huggins GS, Bacani CJ, Boltax J, Aikawa R & Leiden JM 2001 Friend of GATA 2 physically interacts with chicken ovalbumin upstream promoter-TF2 (COUP-TF2) and COUP-TF3 and represses COUP-TF2-dependent activation of the atrial natriuretic factor promoter. Journal of Biological Chemistry 276 28029-28036.
26. Imai S, Armstrong CM, Kaeberlein M & Guarente L 2000 Transcriptional silencing and longevity protein Sir2 is NAD-dependent histone deacetylase. Nature 403 795-800.
27. Ing NH, Beekman JM, Tsai SY, Tsai MJ & O'Malley BW 1992 Members of the steroid hormone receptor superfamily interact with TFIIB (S300-II). Journal of Biological Chemistry 267 17617-17623.
28. Iniguez-Lluhi JA & Pearce D 2000 A common motif within the negative regulatory regions of multiple factors inhibits their transcriptional synergy. Molecular and Cellular Biology 20 6040-6050.
29. Jackson PK 2001 A new RING for SUMO: wrestling transcriptional responses into nuclear bodies with PIAS family E3 SUMO ligases. Genes and Development 15 3053-3058.
30. Kagey MH, Melhuish TA & Wotton D 2003 The polycomb protein Pc2 is a SUMO E3. Cell 113 127-137.
31. Kahyo T, Nishida T & Yasuda H 2001 Involvement of PIAS1 in the sumoylation of tumor suppressor p53. Molecular Cell 8 713-718.
32. Kaul S, Blackford JA Jr, Cho S & Simons SS Jr 2002 Ubc9 is a novel modulator of the induction properties of glucocorticoid receptors. Journal of Biological Chemistry 277 12541-12549.
33. Kim J, Cantwell CA, Johnson PF, Pfarr CM & Williams SC 2002 Transcriptional activity of CCAAT/enhancer binding proteins is controlled by a conserved inhibitory domain that is a target for sumoylation. Journal of Biological Chemistry 277 38037-38044.
34. Kirsh O, Seeler JS, Pichler A, Gast A, Muller S, Miska E, Mathieu M, Harel-Bellan A, Kouzarides T, Melchior F & Dejean A 2002 The SUMO E3 ligase RanBP2 promotes modification of the HDAC4 deacetylase. EMBO Journal 21 2682-2691.
35. Kliewer SA, Umesono K, Heyman RA, Mangelsdorf DJ, Dyck JA & Evans RM 1992a Retinoid X receptor-COUP-TF interactions modulate retinoic acid signaling. Proceedings of the National Academy of Sciences of the United States of America 89 1448-1452.
36. Kliewer SA, Umesono K, Noonan DJ, Heyman RA & Evans RM 1992b Convergence of 9-cis retinoic acid and peroxisome proliferator signalling pathways through heterodimer formation of their receptors. Nature 358 771-774.
37. Kovalenko OV, Plug AW, Haaf T, Gonda DK, Ashley T, Ward DC, Radding CM & Golub EI 1996 Mammalian ubiquitin-conjugating enzyme Ubc9 interacts with Rad51 recombination protein and localizes in synaptonemal complexes. Proceedings of the National Academy of Sciences of the United States of America 93 2958-2963.
38. Ladias JA & Karathanasis SK 1991 Regulation of the apolipoprotein AI gene by ARP-1, a novel member of the steroid receptor superfamily. Science 251 561-565.
39. Le Drean Y, Mincheneau N, Le Goff P & Michel D 2002 Potentiation of glucocorticoid receptor transcriptional activity by sumoylation. Endocrinology 143 3482-3489.
40. Leng X, Cooney AJ, Tsai SY & Tsai MJ 1996 Molecular mechanisms of COUP-TF-mediated transcriptional repression: evidence for transrepression and active repression. Molecular and Cellular Biology 16 2332-2340.
41. McKenna NJ & O'Malley BW 2002 Combinatorial control of gene expression by nuclear receptors and coregulators. Cell 108 465-474.
42. Malik S & Karathanasis S 1995 Transcriptional activation by the orphan nuclear receptor ARP-1. Nucleic Acids Research 23 1536-1543.
43. Marks PA, Rifkind RA, Richon VM, Breslow R, Miller T & Kelly WK 2001 Histone deacetylases and cancer: causes and therapies. Nature Reviews Cancer 1 194-202.
44. Matunis MJ, Wu J & Blobel G 1998 SUMO-1 modification and its role in targeting the Ran GTPase-activating protein, RanGAP1, to the nuclear pore complex. Journal of Cell Biology 140 499-509.
45. Melchior F 2000 SUMO-nonclassical ubiquitin. Annual Review of Cell and Developmental Biology 16 591-626.
46. Muller S, Hoege C, Pyrowolakis G & Jentsch S, 2001 SUMO, ubiquitin's mysterious cousin. Nature Reviews Molecular Cell Biology 2 202-210.
47. Pereira FA, Qiu Y, Tsai MJ & Tsai SY 1995 Chicken ovalbumin upstream promoter transcription factor (COUP-TF): expression during mouse embryogenesis. Journal of Steroid Biochemistry and Molecular Biology 53 503-508.
48. Pichler A & Melchior F 2002 Ubiquitin-related modifier SUMO1 and nucleocytoplasmic transport. Traffic 3 381-387.
49. Pichler A, Gast A, Seeler JS, Dejean A & Melchior F 2002 The nucleoporin RanBP2 has SUMO1 E3 ligase activity. Cell 108 109-120.
50. Pipaon C, Tsai SY & Tsai MJ 1999 COUP-TF upregulates NGFI-A gene expression through an Sp1 binding site. Molecular and Cellular Biology 19 2734-2745.
51. Poukka H, Aarnisalo P, Karvonen U, Palvimo JJ & Janne OA 1999 Ubc9 interacts with the androgen receptor and activates receptor-dependent transcription. Journal of Biological Chemistry 274 19441-19446.
52. Poukka H, Karvonen U, Janne OA & Palvimo JJ 2000 Covalent modification of the androgen receptor by small ubiquitin-like modifier 1 (SUMO-1). Proceedings of the National Academy of Sciences of the United States of America 97 14145-14150.
53. Seeler JS & Dejean A 2001 SUMO: of branched proteins and nuclear bodies. Oncogene 20 7243-7249.
54. Shibata H, Nawaz Z, Tsai SY, O'Malley BW & Tsai MJ 1997a Gene silencing by chicken ovalbumin upstream promoter-transcription factor I (COUP-TFI) is mediated by transcriptional corepressors, nuclear receptor-corepressor (N-CoR) and silencing mediator for retinoic acid receptor and thyroid hormone receptor (SMRT). Molecular Endocrinology & 11 714-724.
55. Shibata H, Spencer TE, Onate SA, Jenster G, Tsai SY, Tsai MJ & O'Malley BW 1997b Role of co-activators and co-repressors in the mechanism of steroid/thyroid receptor action. Recent Progress in Hormone Research 52 141-164.
56. Shibata H, Ando, T, Suzuki T, Kurihara I, Hayashi K, Hayashi M, Saito I, Murai M & Saruta T 1998 COUP-TFI expression in human adrenocortical adenomas: possible role in steroidogenesis. Journal of Clinical Endocrinology and Metabolism 83 4520-4523.
57. Shibata H, Ando T, Kurihara I, Suzuki T, Lund J, Morohashi K, Sasano H, Hayashi K, Hayashi M, Saito I & Saruta T 2000a Functional role of COUP-TFI, SF-1, and nuclear receptor coregulators in the steroidogenesis of adrenocortical adenomas, In Molecular Steroidogenesis, p 345-348. Eds M Okamoto, Y Ishimura & H Nawata. Tokyo: Universal Academy Press, Inc.
58. Shibata H, Ikeda Y, Morohashi K, Mukai T, Kurihara I, Ando T, Suzuki T, Kobayashi S, Hayashi K, Hayashi M, Saito I & Saruta T 2000b Orphan receptors COUP-TF and DAX-1 as targets in disordered CYP17 expression in adrenocortical tumors. Endocrine Research 26 1039-1044.
59. Shibata H, Ikeda Y, Mukai T, Morohashi K, Kurihara I, Ando T, Suzuki T, Kobayashi S, Murai M, Saito I & Saruta T 2001 Expression profiles of COUP-TF, DAX-1, and SF-1 in the human adrenal gland and adrenocortical tumors: possible implications in steroidogenesis. Molecular Genetics and Metabolism 74 206-216.
60. Shibata H, Kobayashi S, Kurihara I, Saito I & Saruta T 2003a Nuclear receptors and co-regulators in adrenal tumors. Hormone Research 59 (suppl 1) 85-93.
61. Shibata H, Kurihara I, Kobayashi S, Yokota K, Suda N, Saito I & Saruta T 2003b Regulation of differential COUP-TF-coregulator interactions in adrenal cortical steroidogenesis. Journal of Steroid Biochemistry and Molecular Biology 85 449-456.
62. Smirnov DA, Hou S & Ricciardi RP 2000 Association of histone deacetylase with COUP-TF in tumorigenic Ad12- transformed cells and its potential role in shut-off of MHC class I transcription. Virology 268 319-328.
63. Sugiyama T, Wang JC, Scott DK & Granner DK 2000 Transcription activation by the orphan nuclear receptor, chicken ovalbumin upstream promoter-transcription factor I (COUP-TFI). Definition of the domain involved in the glucocorticoid response of the phosphoenolpyruvate carboxykinase gene. Journal of Biological Chemistry 275 3446-3454.
64. Tran P, Zhang XK, Salbert G, Hermann T, Lehmann JM & Pfahl M 1992 COUP orphan receptors are negative regulators of retinoic acid response pathways. Molecular and Cellular Biology 12 4666-4676.
65. Tsai SY & Tsai MJ 1997 Chick ovalbumin upstream promoter-transcription factors (COUP-TFs): coming of age. Endocrine Review 18 229-240.
66. Tsai SY, Sagami I, Wang H, Tsai MJ & O'Malley BW 1987 Interactions between a DNA-binding transcription factor (COUP) and a non-DNA binding factor (S300-II). Cell 50 701-709.
67. Verger A, Perdomo J & Crossley M 2003 Modification with SUMO. EMBO Report 4 137-142.
68. Wang LH, Tsai SY, Cook RG, Beattie WG, Tsai MJ & O'Malley BW 1989 COUP transcription factor is a member of the steroid receptor superfamily. Nature 340 163-166.
69. Wang ZY, Qiu QQ, Seufert W, Taguchi T, Testa JR, Whitmore SA, Callen DF, Welsh D, Shenk T & Deuel TF 1996 Molecular cloning of the cDNA and chromosome localization of the gene for human ubiquitin-conjugating enzyme 9. Journal of Biological Chemistry 271 24811-24816.
70. Wilson VG & Rangasamy D 2001 Intracellular targeting of proteins by sumoylation. Experimental Cell Research 271 57-65.
71. Yang SH, Bumpass DC, Perkins ND & Sharrocks AD 2002 The ETS domain transcription factor Elk-1 contains a novel class of repression domain. Molecular and Cellular Biology 22 5036-5046.
72. Zhao HH, Herrera RE, Coronado-Heinsohn E, Yang MC, Ludes-Meyers JH, Seybold-Tilson KJ, Nawaz Z, Yee D, Barr FG, Diab SG, Brown PH, Fuqua SA & Osborne CK 2001 Forkhead homologue in rhabdomyosarcoma functions as a bifunctional nuclear receptor-interacting protein with both coactivator and corepressor functions. Journal of Biological Chemistry 276 27907-27912.