In defense of mucosal surfaces: Regulation and manipulation of the mucosal immune system

Advances in Experimental Medicine and Biology

Volumn 412, Issue , 1997, Pages 373-385

  Elson, C O ^a  

^a University of Alabama at Birmingham   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIGEN; BACTERIUM LIPOPOLYSACCHARIDE; CHOLERA TOXIN; ESCHERICHIA COLI ENTEROTOXIN; HORSERADISH PEROXIDASE; IMMUNOLOGICAL ADJUVANT; KEYHOLE LIMPET HEMOCYANIN; LIPID A; M PROTEIN; MURAMYL DIPEPTIDE; OIL; OVALBUMIN; TETANUS TOXOID; VACCINE; VIRUS HEMAGGLUTININ; WATER;

ARTICLE; DRUG DELIVERY SYSTEM; EMULSION; HOST RESISTANCE; HUMAN; IMMUNIZATION; IMMUNOLOGICAL TOLERANCE; IMMUNOREGULATION; INTESTINE EPITHELIUM; INTESTINE LYMPHATIC TISSUE; INTESTINE MUCOSA; LAMINA PROPRIA; MUCOSAL IMMUNITY; NONHUMAN; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL;

ARMORACIA RUSTICANA; BACTERIA (MICROORGANISMS); ESCHERICHIA COLI;

EID: 0030952462     PISSN: 00652598     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-1-4899-1828-4_60     Document Type: Article

References (68)

1. Abrams, G. D., Bauer, H. and Sprinz, H., 1963, Influence of the normal flora on mucosal morphology and cellular renewal in the ileum. Lab Invest 12: 355-364.
2. Banchereau, J., de Paoli, P., Valle, A., Garcia, E. and Roussett, F., 1991, Long-term human B cell lines dependent on interleukin-4 and antibody to CD40. Science 251: 70-72.
3. Beagley, K. W. and Elson, C. O., 1992, Cells and cytokines in mucosal immunity and inflammation. Gastroenterol Clin North Am . 21: 347-366.
4. Beagley, K. W., Fujihashi, K., Lagoo, A. S. and Elson, C. O., 1992, Regional differences in mucosal lymphoid cells of murine small vs. large bowel. Gastroenterology . 102: A593.
5. Bland, P. W. and Kambarage, D. M., 1991, Antigen handling by the epithelium and lamina propria macrophages. Gastroenterol Clin North Am . 20: 577-596.
6. Blumberg, R. S., Yockey, C. and Balk, S. P., 1992, Oligoclonal expansion of human intestinal alpha-beta T lymphocytes in epithelium and lamina propria. Gastroenterology . 102: A597.
7. Bockman, D. E., Boydston, W. R. and Beezhold, D. H., 1983, The role of epithelial cells in gut-associated immune reactivity. Ann N Y Acad Sci. 409: 129-143.
8. Brandtzaeg, P., 1985, Research in gastrointestinal immunology. State of the art. Scand J Gastroent . 20: 137-156.
9. Brandtzaeg, P., Valnes, K., Scott, H., Rognum, T. O., Bjerke, K. and Baklein, K., 1985, The human gastrointestinal secretory immune system in health and disease. Scand J Gastroent . 20: 17-38.
10. Brisken, M. J., McEvoy, L. M. and Butcher, E. C., 1993, MAdCAM-1 has homology to immunoglobulin and mucin-like adhesion receptors and to IgA1. Nature . 363: 461-464.
11. Cebra, J. J., Komisar, J. L. and Schweitzer, P. A., 1984, CH isotype switching during normal B-lymphocyte development. Ann Rev Immunol . 2: 493-548.
12. Sussan, N. and Guy-Grand, D., 1992, Intestinal Intraepithelial lymphocytes. Gastroenterol Clin North Am . 21: 549-576.
13. Cerf-Bensussan, N., Quaroni, A., Kurnick, J. T. and Bhan, A. K., 1984, Intraepithelial lymphocytes modulate la expression by intestinal epithelial cells. J Immunol . 132: 2244-2252.
14. Coffman, R. L., Lebman, D. A. and Shrader, B., 1989, Transforming growth factor beta specifically enhances IgA production by lipopolysaccharide-stimulated murine B lymphocytes. J Exp Med . 170: 1039-1044.
15. Crabbe, P. A., Bazin, H., Eyssen, H. and Heremans, J. F., 1968, The normal microbial flora as a major stimulus for proliferation of plasma cells synthesizing IgA in the gut. The germ-free intestinal tract. Int Arch Allergry . 34: 362-375.
16. Craig, S. W. and Cebra, J. J., 1971, Peyer's patches: an enriched source of precursors for IgA-producing immunocytes in the rabbit. J Exp Med . 134: 188-200.
17. Dertzbaugh, M. T. and Elson, C. O., 1993, Comparative effectiveness of the cholera toxin B subunit and alkaline phosphatase as carriers for oral vaccines. Infect Immun . 61: 48-55.
18. Eckmann, L., Kagnoff, M. F. and Fierer, J., 1993, Epithelial cells secrete the chemokine interleukin-8 in response to bacterial entry. Infect Immun . 61: 4569-4674.
19. Elson, C. O., 1985. Induction and control of the gastrointestinal immune system. Scand J Gastroent. 20: suppl. 114:1-15.
20. Elson, C. O., 1992, Cholera toxin as a mucosal adjuvant: effects of H-2 major histocompatibility complex and lps genes. Infect Immun . 60: 2874-2879.
21. Elson, C. O. and Dertzbaugh, M. T., 1994, Mucosal Adjuvants. In "Handbook of Mucosal Immunology". (P. L. Ogra, J. Mestecky, M. E. Lammet al, Ed.), pp. 391-402, Academic Press, San Diego.
22. Elson, C. O. and Ealding, W., 1984, Cholera toxin feeding did not induce oral tolerance in mice and abrogated oral tolerance to an unrelated protein antigen. J. Immunol. . 133: 2892-2897.
23. Elson, C. O. and McCabe, R. P. J., 1995, The immunology of inflammatory bowel disease. In "Inflammatory Bowel Disease". 4th, ed. (J. B. Kirsner and R. G. Shorter, Ed.), pp. 203-251, Williams & Wilkins, Baltimore.
24. Ferguson, A., 1977. Intraepithelial lymphocytes of the small intestine. Gut . 18: 921-937.
25. Gearhart, P. J. and Cebra, J. J., 1979, Differentiated B lymphocytes. Potential to express particular antibody variable and constant regions depends on site of lymphoid tissue and antigen load. J. Exp Med . 149: 216-227.
26. Goldblum, R. M., Ahlstedt, S., Carlsson, B., Hanson, L. A., Jodal, U., Lidin Janson, G. and Sohl-Ackerlund, A., 1975, Antibody forming cells in human colostrum after oral immunization. Nature (London) . 257: 797-799.
27. Guy-Grand, D., Griscelli, C. and Vassalli, P., 1974, The gut-associated lymphoid system: nature and properties of the large dividing cells. Eur J Immunol. 4: 435-443.
28. Guy-Grand, D., Griscelli, C. and Vassalli, P., 1975. Peyer's patches, gut IgA plasma cells and thymic function: Study in nude mice bearing thymic grafts. J Immunol . 115: 361-364.
29. Guy-Grand, D., Grisceili, C. and Vassalli, P., 1978. The mouse gut T lymphocyte, a novel type of T cell. Nature, origin, and traffic in mice in normal and graft-versus-host conditions. J Exp Med . 148: 1661-1667.
30. Heinzel, F., Sadick, M., Holoday, B., Coffman, R. and Locksley, R., 1989, Reciprocal expression of interferon gamma or interleukin 4 during the resolution or progression of murine leischmaniaisis. Evidence for expansion of distinct helper T cell subsets. J Exp Med. 169: 59-72.
31. Herbert, W. J., 1965. Multiple emulsions, A new form of mineral-oil antigen adjuvant. Lancet . 2: 771.
32. Hunter, R. L., Olsen, M. R. and Bennett, B., 1995. Copolymer adjuvants and Titermax. In "Theory and Practical Applications of Adjuvants". (D. E. S. Siewart-Tull, Ed.), pp. 52-94, John Wiley & Sons, New York.
33. James, S. P., 1992. Mucosal T-ecll function. Gastroenterol Clin N Am . 20: 597-612.
34. Kagnoff, M. F., 1977. Functional characteristics of Peyer's patch cells. IV. Effect of antigen feeding on the frequency of antigen-specific B cells. J Immunol . 118: 992-997.
35. Kawanishi, H., Saltzman, L. E. and Slrober, W., 1983, Mechanisms regulating IgA class-specific immunoglobulin production in murine gut-associated lymphoid tissues. I. T cells derived from Peyer's patches that switch slgM B cells in vitro. J Exp Med . 157: 433-449.
36. Khoury, S. J., Lider, O., Al-Sabbagh, A. and Weiner, H. L., 1990, Suppression of experimental autoimmune encephalomyelitis by oral administration of myelin basic protein. III. Synergistic effect of lipopolysaccharide. Cell Immunol. 131: 302 -310.
37. Kilian, M., Mestecky, J. and Russell, M. W., 1988, Defense mechanisms involving Fc-dependent functions of immunoglobulin A (IgA) and their subversion by bacterial immunoglobulin A proteases. Microbiol Rev . 52: 296-303.
38. Koizumi, M., King, N., Lobb, R., Benjamin, C. and Podolsky, D. K., 1992, Expression of vascular adhesion molecules in inflammatory bowel disease. Gastroenterology . 103; 840-847.
39. Koyama, S. Y. and Podolsky, D. K., 1989. Differential expression of transforming growth factors alpha and beta in rat intestinal epithelial cells. J Clin Invest . 83: 1768-1773.
40. Lebman, D. A., Lee, F. D. and Coffman, R. L., 1990, Mechanism for transforming growth factor beta and IL-2 enhancement of IgA expression in lipopolysaccharide-stimulated B cell cultures. J Immunol. 144: 952-958.
41. Lycke, N. and Holmgren, J., 1986, Intestinal mucosal memory and presence of memory cells in lamina propria and Peyer's patches in mice 2 years after oral immunization with cholera toxin. Scand J Immunol . 23: 611-616.
42. Lycke, N. and Holmgren, J., 1986, Strong adjuvant properties of cholera toxin on gut mucosal immune responses to orally presented antigens. Immunology . 59: 301-308.
43. Mattioli, C. A. and Tomasi, T. B. J., 1973. The life span of IgA plasma cells from the mouse intestine. J Exp Med . 138: 452-460.
44. McGee, D. W., Beagley, K. W., Aicher, W. K. and McGhee, J. R., 1992, Transforming growth factor-beta enhanced interleukin-6 secretion by intestinal epithelial cells. Immunology . 77: 7-12.
45. McGhee, J. R. and Mestecky, J., 1990, In defense of mucosal surfaces. Development of novel vaccines for IgA responses protective at portals of entry for microbial pathogens. Infect Dis Clin North Amer . 4: 315-341.
46. McGhee, J. R., Mestecky, J., Elson, C. O. and Kiyono, H., 1989, Regulation of IgA synthesis and immune response by T cells and interleukins. J Clin Immunol . 9: 175-199.
47. Miller, A., Lider, O., Roberts, A. B., Sporn, M. B. and Weiner, H. L., 1992, Suppressor T cells generated by oral tolerization to myelin basic protein suppress both in vitro and in vivo immune responses by the release of transforming growth factor beta after antigen-specific triggering. Proc Natl Acad Sci USA. 89: 421-425.
48. Mosley, R. L., Styre, D. and Klein, J. R., 1990, Differentiation and functional maturation of bone marrow-derived intestinal epithelial T cells expressing membrane T cell receptor in athymic radiation chimeras. J Immunol 145: 1369-1375.
49. Mosmann, T. R. and Coffman, R. L., 1989, Th1 and Th2 cells: different patterns of lymphokine secretion lead to different functional properties. Ann. Rev. Immunol. . 1: 145-174.
50. Owen, R. L., 1983, And now pathophysiology of M cells- good news and bad news from Peyer's patches. Gustroenterology . 85: 468-470.
51. Owen, R. L. and Jones, A. L., 1974, Epithelial cell specialization within human Peyer's patches: and ultrastructural study of intestinal lymphoid follicles. Gastroenterology . 66: 189-203.
52. Picker, L. J. and Butcher, E. C., 1992. Physiological and molecular mechanisms of lymphocyte homing. A unit Rev Immunol . 10: 561-591.
53. Qiao, L., Schurmann, G., Betzler, M. and Meuer, S. C., 1991, Activation and signaling status of human lamina propria T lymphocytes. Gastroenterology . 101: 1529-1536.
54. Raqib, R., Lindberg, A.A., Bjork, L., Bardhan, P.K., Wretlind, B., Andersson, U. and Andersson, A. 1995. Down regulation of gamma interferon. tumor necrosis factor type I, interleukin I (IL-1), type I, IL-3, IL-4, and transforming growth factor β type I receptors at the local site during the acute phase of Shigella infection. Infect Immun . 63: 3079-3087.
55. Salmi, M. and Jalkanen, S., 1991. Regulation of lymphocyte traffic to mucosa-associated lymphatic tissues. Gastroenterol Clin North Am . 20: 495-510.
56. Salomon, P., Pizzimenti, A., Panja, A., Reisman, A. and Mayer, L., 1991. The expression and regulation of class II antigens in normal and inflammatory bowel disease peripheral blood monocytes and intestinal epithelium. Autoimmunity . 9: 141-149.
57. Sanderson, I. R., Ouellette, A. J., Carter, E. A., Walker, W. A. and Harmatz, P. R., 1993. Differential regulation of B7 mRNA in enterocytes and lymphoid cells. Immunology . 79: 434-438.
58. Savage, D. C., 1977, Microbial ecology of the gastrointestinal tract. Annu Rev Microbiol . 31: 107-133.
59. Scicchitano, R., Stanisz, A., Ernst, P. and Bienenstock, J., 1988. A common mucosal immune system revisited. In "Migration and Homing of Lvmphoid Cells". (A. J. Husband, Ed.), pp. 1-35, CRC Press, Boca Rotan.
60. Shanahan, F., Brogan, M. and Targan, S., 1987, Human mucosal cytotoxic effector cells. Gastroenterology . 92: 1951-1957.
61. Spalding, D. M., Williamson, S. I., Koopman, W. J. and McGhee, J. R., 1984, Preferential induction of polyclonal IgA secretion by murine Peyer's patch dendritic cell-T cell mixtures. J Exp Med . 160: 941-.
62. Strober, W., Hanson, L. A. and Sell, K. W., Eds., "Recent advances in mucosal immunity. Raven Press, New York, 1982," pp. 1982.
63. Tomasi, M., Dertzbaugh, M., Hunter, H. and Elson, C., 1994, Use of multiple emulsions containing cholera toxin (CT) for mucosal immunization. FASEB Journal. 8: A283.
64. Trier, J. S., 1992, Structure and function of intestinal M cells. Gastroenterol Clin North Am . 20: 531-548.
65. Tseng, J., 1981, Transfer of lymphocytes of Peyer's patches between immunoglobulin allotype congenic mice: repopulation of the IgA plasma cells in the gut lamina propria. J Immunol. 127: 2039-2043.
66. Vajdy, M. and Lycke, N., 1993, Stimulation of antigen-specific T- and B-cell memory in local as well as systemic lymphoid tissues following oral immunization with cholera toxin adjuvant. Immunology . 80: 197-203.
67. Xu-Amano, J., Jackson, R. J., Staats, H. F., Fujihashi, K., Kiyono, H., Burrows, P. D., Elson, C. O., Pillai, S. and McGhee, J. R., 1993, Helper T cell subsets for IgA responses. Oral immunization with tetanus toxoid and cholera toxin as adjuvant selectively induces Th2 cells in mucosa-associated tissues. J Exp Med . 178: 1309-1320.
68. Zeitz, M., Quinn, T. C., Graeff, A. S. and James, S. P., 1988. Mucosal T cells provide helper function but do not proliferate when stimulated by specific antigen in lymphogranuloma venereum proctitis in nonhuman primates. Gastroenterology . 94: 353-366.